Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
2 Adherens junction 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
3 Adherens junction 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
4 Adherens junction 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
5 Adherens junction 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
6 Adherens junction 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
7 Adherens junction 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
8 Bladder cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
9 Bladder cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
10 Bladder cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
11 Bladder cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
12 Bladder cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
13 Bladder cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
14 Bladder cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
15 Breast cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
16 Breast cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
17 Breast cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
18 Breast cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
19 Breast cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
20 Breast cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
21 Breast cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
22 Calcium signaling pathway 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
23 Calcium signaling pathway 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
24 Calcium signaling pathway 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
25 Calcium signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
26 Calcium signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
27 Calcium signaling pathway 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
28 Calcium signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
29 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
30 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
31 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
32 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
33 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
34 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
35 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
36 Endometrial cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
37 Endometrial cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
38 Endometrial cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
39 Endometrial cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
40 Endometrial cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
41 Endometrial cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
42 Endometrial cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
43 ErbB signaling pathway 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
44 ErbB signaling pathway 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
45 ErbB signaling pathway 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
46 ErbB signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
47 ErbB signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
48 ErbB signaling pathway 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
49 ErbB signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
50 Focal adhesion 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
51 Focal adhesion 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
52 Focal adhesion 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
53 Focal adhesion 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
54 Focal adhesion 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
55 Focal adhesion 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
56 Focal adhesion 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
57 Gastric cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
58 Gastric cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
59 Gastric cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
60 Gastric cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
61 Gastric cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
62 Gastric cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
63 Gastric cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
64 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
65 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
66 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
67 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
68 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
69 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
70 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
71 MAPK signaling pathway 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
72 MAPK signaling pathway 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
73 MAPK signaling pathway 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
74 MAPK signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
75 MAPK signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
76 MAPK signaling pathway 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
77 MAPK signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
78 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
79 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
80 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
81 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
82 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
83 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
84 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
85 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
86 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
87 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
88 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
89 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
90 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
91 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
92 Pancreatic cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
93 Pancreatic cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
94 Pancreatic cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
95 Pancreatic cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
96 Pancreatic cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
97 Pancreatic cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
98 Pancreatic cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
99 Pathways in cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
100 Pathways in cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
101 Pathways in cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
102 Pathways in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
103 Pathways in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
104 Pathways in cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
105 Pathways in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
106 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
107 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
108 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
109 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
110 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
111 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
112 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
113 Prostate cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
114 Prostate cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
115 Prostate cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
116 Prostate cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
117 Prostate cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
118 Prostate cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
119 Prostate cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
120 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
121 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
122 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
123 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
124 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
125 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
126 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
127 Tight junction 💬
 [1] ERBB2 💬 Afatinib 💬 Afatinib [1] 285 💬
128 Tight junction 💬
 [1] ERBB2 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
129 Tight junction 💬
 [1] ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
130 Tight junction 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
131 Tight junction 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
132 Tight junction 💬
 [1] ERBB2 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
133 Tight junction 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬

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