Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
2 Adherens junction 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
3 Adherens junction 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
4 Bladder cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
5 Bladder cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
6 Bladder cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
7 Breast cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
8 Breast cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
9 Breast cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
10 Calcium signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
11 Calcium signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
12 Calcium signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
13 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
14 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
15 Central carbon metabolism in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
16 EGFR tyrosine kinase inhibitor resistance 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
17 EGFR tyrosine kinase inhibitor resistance 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
18 EGFR tyrosine kinase inhibitor resistance 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
19 Endocrine resistance 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
20 Endocrine resistance 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
21 Endocrine resistance 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
22 Endometrial cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
23 Endometrial cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
24 Endometrial cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
25 ErbB signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
26 ErbB signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
27 ErbB signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
28 Focal adhesion 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
29 Focal adhesion 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
30 Focal adhesion 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
31 Gastric cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
32 Gastric cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
33 Gastric cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
34 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
35 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
36 HIF-1 signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
37 MAPK signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
38 MAPK signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
39 MAPK signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
40 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
41 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
42 MicroRNAs in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
43 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
44 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
45 Non-small cell lung cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
46 Pancreatic cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
47 Pancreatic cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
48 Pancreatic cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
49 Pathways in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
50 Pathways in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
51 Pathways in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
52 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
53 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
54 PI3K-Akt signaling pathway 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
55 Platinum drug resistance 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
56 Platinum drug resistance 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
57 Platinum drug resistance 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
58 Prostate cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
59 Prostate cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
60 Prostate cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
61 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
62 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
63 Proteoglycans in cancer 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
64 Tight junction 💬
 [1] ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
65 Tight junction 💬
 [1] ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬
66 Tight junction 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬

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