Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Breast cancer 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
2 Breast cancer 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
3 Breast cancer 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
4 Breast cancer 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
5 Breast cancer 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
6 Breast cancer 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
7 Breast cancer 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
8 Breast cancer 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
9 Breast cancer 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
10 Breast cancer 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
11 Breast cancer 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
12 Breast cancer 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
13 Breast cancer 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
14 Breast cancer 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
15 Breast cancer 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
16 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
17 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
18 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
19 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
20 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
21 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
22 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
23 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
24 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
25 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
26 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
27 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
28 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
29 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
30 Chemical carcinogenesis - receptor activation 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
31 Estrogen signaling pathway 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
32 Estrogen signaling pathway 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
33 Estrogen signaling pathway 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
34 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
35 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
36 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
37 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
38 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
39 Estrogen signaling pathway 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
40 Estrogen signaling pathway 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
41 Estrogen signaling pathway 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
42 Estrogen signaling pathway 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
43 Estrogen signaling pathway 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
44 Estrogen signaling pathway 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
45 Estrogen signaling pathway 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
46 GnRH secretion 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
47 GnRH secretion 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
48 GnRH secretion 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
49 GnRH secretion 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
50 GnRH secretion 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
51 GnRH secretion 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
52 GnRH secretion 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
53 GnRH secretion 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
54 GnRH secretion 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
55 GnRH secretion 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
56 GnRH secretion 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
57 GnRH secretion 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
58 GnRH secretion 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
59 GnRH secretion 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
60 GnRH secretion 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
61 Hormone signaling 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
62 Hormone signaling 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
63 Hormone signaling 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
64 Hormone signaling 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
65 Hormone signaling 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
66 Hormone signaling 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
67 Hormone signaling 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
68 Hormone signaling 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
69 Hormone signaling 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
70 Hormone signaling 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
71 Hormone signaling 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
72 Hormone signaling 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
73 Hormone signaling 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
74 Hormone signaling 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
75 Hormone signaling 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
76 Pathways in cancer 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
77 Pathways in cancer 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
78 Pathways in cancer 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
79 Pathways in cancer 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
80 Pathways in cancer 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
81 Pathways in cancer 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
82 Pathways in cancer 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
83 Pathways in cancer 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
84 Pathways in cancer 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
85 Pathways in cancer 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
86 Pathways in cancer 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
87 Pathways in cancer 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
88 Pathways in cancer 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
89 Pathways in cancer 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
90 Pathways in cancer 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
91 Prolactin signaling pathway 💬
 [1] ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
92 Prolactin signaling pathway 💬
 [1] ESR2 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
93 Prolactin signaling pathway 💬
 [1] ESR2 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
94 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
95 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estetrol 💬 Estetrol [1] 53 💬
96 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
97 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
98 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estriol 💬 Estriol [2] 13, 227 💬
99 Prolactin signaling pathway 💬
 [1] ESR2 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
100 Prolactin signaling pathway 💬
 [1] ESR2 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
101 Prolactin signaling pathway 💬
 [1] ESR2 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
102 Prolactin signaling pathway 💬
 [1] ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
103 Prolactin signaling pathway 💬
 [1] ESR2 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
104 Prolactin signaling pathway 💬
 [1] ESR2 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
105 Prolactin signaling pathway 💬
 [1] ESR2 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬

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