About Icons

Icon	Function
💬	A pop-up explanation appears when you mouse-over the text beside this icon. Also, an explanation window appears when you click this icon.
	The links beside this icon are links to external sites.
	Clicking this icon sorts the table by the item with this icon (Numerical or alphabetical order). Each click toggles between ascending and descending order.
	A text longer than 100 characters is fully displayed or collapsed.
	The contents of the displayed table are downloaded as a file named "table.csv".

Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

cAMP signaling pathway 💬

[1] GLP1R 💬

Dulaglutide 💬

[1] 299 💬

2

cAMP signaling pathway 💬

[1] GLP1R 💬

[5] 6 , 17, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

3

cAMP signaling pathway 💬

[1] GLP1R 💬

Liraglutide 💬

[5] 6 , 13, 75, 77, 193 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
75	Cushing disease;Cushing syndrome;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
193	Prader-Willi syndrome;

4

cAMP signaling pathway 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

5

cAMP signaling pathway 💬

[1] GLP1R 💬

Semaglutide 💬

[4] 6 , 51, 84, 299 💬

6

cAMP signaling pathway 💬

[1] GLP1R 💬

Tirzepatide 💬

[5] 67, 96, 97, 193, 233 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

7

Hormone signaling 💬

[1] GLP1R 💬

Dulaglutide 💬

[1] 299 💬

8

Hormone signaling 💬

[1] GLP1R 💬

[5] 6 , 17, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

9

Hormone signaling 💬

[1] GLP1R 💬

Liraglutide 💬

[5] 6 , 13, 75, 77, 193 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
75	Cushing disease;Cushing syndrome;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
193	Prader-Willi syndrome;

10

Hormone signaling 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

11

Hormone signaling 💬

[1] GLP1R 💬

Semaglutide 💬

[4] 6 , 51, 84, 299 💬

12

Hormone signaling 💬

[1] GLP1R 💬

Tirzepatide 💬

[5] 67, 96, 97, 193, 233 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

13

Insulin secretion 💬

[1] GLP1R 💬

Dulaglutide 💬

[1] 299 💬

14

Insulin secretion 💬

[1] GLP1R 💬

[5] 6 , 17, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

15

Insulin secretion 💬

[1] GLP1R 💬

Liraglutide 💬

[5] 6 , 13, 75, 77, 193 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
75	Cushing disease;Cushing syndrome;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
193	Prader-Willi syndrome;

16

Insulin secretion 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

17

Insulin secretion 💬

[1] GLP1R 💬

Semaglutide 💬

[4] 6 , 51, 84, 299 💬

18

Insulin secretion 💬

[1] GLP1R 💬

Tirzepatide 💬

[5] 67, 96, 97, 193, 233 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

19

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Dulaglutide 💬

[1] 299 💬

20

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

[5] 6 , 17, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

21

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Liraglutide 💬

[5] 6 , 13, 75, 77, 193 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
75	Cushing disease;Cushing syndrome;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;Acromegaly;
193	Prader-Willi syndrome;

22

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Lixisenatide 💬

[1] 6 💬

23

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Semaglutide 💬

[4] 6 , 51, 84, 299 💬

24

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Tirzepatide 💬

[5] 67, 96, 97, 193, 233 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;