Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Amphetamine addiction 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
2 Amphetamine addiction 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
3 Amphetamine addiction 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
4 Amphetamine addiction 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
5 Amphetamine addiction 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
6 Amphetamine addiction 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
7 Amphetamine addiction 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
8 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
9 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
10 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
11 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
12 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
13 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
14 Amyotrophic lateral sclerosis 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
15 cAMP signaling pathway 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
16 cAMP signaling pathway 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
17 cAMP signaling pathway 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
18 cAMP signaling pathway 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
19 cAMP signaling pathway 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
20 cAMP signaling pathway 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
21 cAMP signaling pathway 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
22 Circadian entrainment 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
23 Circadian entrainment 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
24 Circadian entrainment 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
25 Circadian entrainment 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
26 Circadian entrainment 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
27 Circadian entrainment 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
28 Circadian entrainment 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
29 Cocaine addiction 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
30 Cocaine addiction 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
31 Cocaine addiction 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
32 Cocaine addiction 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
33 Cocaine addiction 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
34 Cocaine addiction 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
35 Cocaine addiction 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
36 Dopaminergic synapse 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
37 Dopaminergic synapse 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
38 Dopaminergic synapse 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
39 Dopaminergic synapse 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
40 Dopaminergic synapse 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
41 Dopaminergic synapse 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
42 Dopaminergic synapse 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
43 Glutamatergic synapse 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
44 Glutamatergic synapse 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
45 Glutamatergic synapse 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
46 Glutamatergic synapse 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
47 Glutamatergic synapse 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
48 Glutamatergic synapse 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
49 Glutamatergic synapse 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
50 Huntington disease 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
51 Huntington disease 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
52 Huntington disease 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
53 Huntington disease 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
54 Huntington disease 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
55 Huntington disease 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
56 Huntington disease 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
57 Long-term depression 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
58 Long-term depression 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
59 Long-term depression 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
60 Long-term depression 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
61 Long-term depression 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
62 Long-term depression 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
63 Long-term depression 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
64 Long-term potentiation 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
65 Long-term potentiation 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
66 Long-term potentiation 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
67 Long-term potentiation 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
68 Long-term potentiation 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
69 Long-term potentiation 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
70 Long-term potentiation 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
71 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
72 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
73 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
74 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
75 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
76 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
77 Neuroactive ligand signaling 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
78 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
79 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
80 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
81 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
82 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
83 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
85 Nicotine addiction 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
86 Nicotine addiction 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
87 Nicotine addiction 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
88 Nicotine addiction 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
89 Nicotine addiction 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
90 Nicotine addiction 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
91 Nicotine addiction 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
92 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
93 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
94 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
95 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
96 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
97 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
98 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
99 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
100 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
101 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
102 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
103 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
104 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
105 Retrograde endocannabinoid signaling 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
106 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
107 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
108 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
109 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
110 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
111 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Troriluzole 💬 Troriluzole [1] 18 💬
112 Spinocerebellar ataxia 💬
 [1] GRIA2 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬

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