Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
2 Alcoholism 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
3 Alcoholism 💬
 [10] HDAC10, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
4 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
5 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
6 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
7 Amyotrophic lateral sclerosis 💬
 [1] HDAC6 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
8 Amyotrophic lateral sclerosis 💬
 [1] HDAC6 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
9 Amyotrophic lateral sclerosis 💬
 [1] HDAC6 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
10 Apelin signaling pathway 💬
 [2] HDAC4_5, HDAC4_5 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
11 Apelin signaling pathway 💬
 [2] HDAC4_5, HDAC4_5 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
12 Apelin signaling pathway 💬
 [2] HDAC4_5, HDAC4_5 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
13 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
14 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
15 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
16 Cell cycle 💬
 [3] HDAC1_2, HDAC1_2, HDAC8 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
17 Cell cycle 💬
 [3] HDAC1_2, HDAC1_2, HDAC8 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
18 Cell cycle 💬
 [3] HDAC1_2, HDAC1_2, HDAC8 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
19 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
20 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
21 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
22 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
23 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
24 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
25 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
26 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
27 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
28 Huntington disease 💬
 [1] HD 💬 Tominersen 💬 Tominersen [1]  8  💬
29 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
30 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
31 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
32 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
33 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
34 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
35 MicroRNAs in cancer 💬
 [4] HDAC1_2, HDAC1_2, HDAC4_5, HDAC4_5 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
36 MicroRNAs in cancer 💬
 [4] HDAC1_2, HDAC1_2, HDAC4_5, HDAC4_5 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
37 MicroRNAs in cancer 💬
 [4] HDAC1_2, HDAC1_2, HDAC4_5, HDAC4_5 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
38 Neutrophil extracellular trap formation 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
39 Neutrophil extracellular trap formation 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
40 Neutrophil extracellular trap formation 💬
 [10] HDAC10, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
41 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
42 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
43 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
44 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
45 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
46 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
47 Pathways of neurodegeneration - multiple diseases 💬
 [1] HD 💬 Tominersen 💬 Tominersen [1]  8  💬
48 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
49 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
50 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
51 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
52 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
53 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
54 Thyroid hormone signaling pathway 💬
 [3] HDAC1_2, HDAC1_2, HDAC3 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
55 Thyroid hormone signaling pathway 💬
 [3] HDAC1_2, HDAC1_2, HDAC3 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
56 Thyroid hormone signaling pathway 💬
 [3] HDAC1_2, HDAC1_2, HDAC3 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
57 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
58 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
59 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
60 Viral carcinogenesis 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
61 Viral carcinogenesis 💬
 [11] HDAC10, HDAC11, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
62 Viral carcinogenesis 💬
 [10] HDAC10, HDAC1_2, HDAC1_2, HDAC3, HDAC4_5, HDAC4_5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬

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