Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
2 Alcoholism 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
3 Alcoholism 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
4 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
5 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
6 Amphetamine addiction 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
7 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
8 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
9 ATP-dependent chromatin remodeling 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
10 Cell cycle 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
11 Cell cycle 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
12 Cell cycle 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
13 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
14 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
15 Chronic myeloid leukemia 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
16 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
17 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
18 Epstein-Barr virus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
19 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
20 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
21 Human papillomavirus infection 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
22 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
23 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
24 Huntington disease 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
25 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
26 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
27 Longevity regulating pathway - multiple species 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
28 MicroRNAs in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
29 MicroRNAs in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
30 MicroRNAs in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
31 Neutrophil extracellular trap formation 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
32 Neutrophil extracellular trap formation 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
33 Neutrophil extracellular trap formation 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
34 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
35 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
36 Notch signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
37 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
38 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
39 Pathways in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
40 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
41 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
42 Polycomb repressive complex 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
43 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
44 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
45 TGF-beta signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
46 Thyroid hormone signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
47 Thyroid hormone signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
48 Thyroid hormone signaling pathway 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
49 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
50 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
51 Transcriptional misregulation in cancer 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
52 Viral carcinogenesis 💬
 [2] HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat [1] 75 💬
53 Viral carcinogenesis 💬
 [2] HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat [2] 107, 113 💬
54 Viral carcinogenesis 💬
 [2] HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬

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