Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 cAMP signaling pathway 💬
 [1] HTR1 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
2 cAMP signaling pathway 💬
 [1] HTR1 💬 Buspirone hydrochloride 💬 Buspirone [3]  6 , 51, 179 💬
3 cAMP signaling pathway 💬
 [1] HTR1 💬 Buspirone 💬 Buspirone [3]  6 , 51, 179 💬
4 cAMP signaling pathway 💬
 [1] HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox [1]  6  💬
5 cAMP signaling pathway 💬
 [1] HTR1 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
6 cAMP signaling pathway 💬
 [1] HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan [2]  6 , 156 💬
7 cAMP signaling pathway 💬
 [1] HTR1 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
8 cAMP signaling pathway 💬
 [1] HTR1 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
9 cAMP signaling pathway 💬
 [1] HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
10 cAMP signaling pathway 💬
 [1] HTR1 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
11 cAMP signaling pathway 💬
 [2] HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬
12 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
13 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Buspirone hydrochloride 💬 Buspirone [3]  6 , 51, 179 💬
14 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Buspirone 💬 Buspirone [3]  6 , 51, 179 💬
15 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox [1]  6  💬
16 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
17 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan [2]  6 , 156 💬
18 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
19 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
20 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
21 Neuroactive ligand signaling 💬
 [1] HTR1 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
22 Neuroactive ligand signaling 💬
 [2] HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬
23 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
24 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Buspirone hydrochloride 💬 Buspirone [3]  6 , 51, 179 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Buspirone 💬 Buspirone [3]  6 , 51, 179 💬
26 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox [1]  6  💬
27 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
28 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan [2]  6 , 156 💬
29 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
30 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
31 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
32 Neuroactive ligand-receptor interaction 💬
 [1] HTR1 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
33 Neuroactive ligand-receptor interaction 💬
 [2] HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬
34 Serotonergic synapse 💬
 [1] HTR1 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
35 Serotonergic synapse 💬
 [1] HTR1 💬 Buspirone hydrochloride 💬 Buspirone [3]  6 , 51, 179 💬
36 Serotonergic synapse 💬
 [1] HTR1 💬 Buspirone 💬 Buspirone [3]  6 , 51, 179 💬
37 Serotonergic synapse 💬
 [1] HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox [1]  6  💬
38 Serotonergic synapse 💬
 [1] HTR1 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
39 Serotonergic synapse 💬
 [1] HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan [2]  6 , 156 💬
40 Serotonergic synapse 💬
 [1] HTR1 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
41 Serotonergic synapse 💬
 [1] HTR1 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
42 Serotonergic synapse 💬
 [1] HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
43 Serotonergic synapse 💬
 [1] HTR1 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
44 Serotonergic synapse 💬
 [2] HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬
45 Taste transduction 💬
 [1] HTR1 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
46 Taste transduction 💬
 [1] HTR1 💬 Buspirone hydrochloride 💬 Buspirone [3]  6 , 51, 179 💬
47 Taste transduction 💬
 [1] HTR1 💬 Buspirone 💬 Buspirone [3]  6 , 51, 179 💬
48 Taste transduction 💬
 [1] HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox [1]  6  💬
49 Taste transduction 💬
 [1] HTR1 💬 Pardoprunox 💬 Pardoprunox [1]  6  💬
50 Taste transduction 💬
 [1] HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan [2]  6 , 156 💬
51 Taste transduction 💬
 [1] HTR1 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
52 Taste transduction 💬
 [1] HTR1 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
53 Taste transduction 💬
 [1] HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
54 Taste transduction 💬
 [1] HTR1 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
55 Taste transduction 💬
 [2] HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan [1]  6  💬

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