Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
2 Calcium signaling pathway 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
3 Calcium signaling pathway 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
4 Calcium signaling pathway 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
5 Calcium signaling pathway 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
6 Calcium signaling pathway 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
7 Calcium signaling pathway 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
8 Calcium signaling pathway 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
9 Calcium signaling pathway 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
10 Calcium signaling pathway 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
11 Calcium signaling pathway 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
12 Calcium signaling pathway 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
13 Calcium signaling pathway 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
14 Calcium signaling pathway 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
15 Calcium signaling pathway 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
16 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
17 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
18 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
19 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
20 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
21 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
22 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
23 Calcium signaling pathway 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
24 Gap junction 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
25 Gap junction 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
26 Gap junction 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
27 Gap junction 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
28 Gap junction 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
29 Gap junction 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
30 Gap junction 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
31 Gap junction 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
32 Gap junction 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
33 Gap junction 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
34 Gap junction 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
35 Gap junction 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
36 Gap junction 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
37 Gap junction 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
38 Gap junction 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
39 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
40 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
41 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
42 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
43 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
44 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
45 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
46 Gap junction 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
47 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
48 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
49 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
50 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
51 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
52 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
53 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
54 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
55 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
56 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
57 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
58 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
59 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
60 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
61 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
62 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
63 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
64 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
65 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
66 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
67 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
68 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
69 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
70 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
71 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
72 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
73 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
74 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
75 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
76 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
77 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
78 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
79 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
80 Neuroactive ligand signaling 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
81 Neuroactive ligand signaling 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
82 Neuroactive ligand signaling 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
83 Neuroactive ligand signaling 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
84 Neuroactive ligand signaling 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
85 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
86 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
87 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
88 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
89 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
90 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
91 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
92 Neuroactive ligand signaling 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
93 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
94 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
95 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
96 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
97 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
98 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
99 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
100 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
101 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
102 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
103 Neuroactive ligand-receptor interaction 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
104 Neuroactive ligand-receptor interaction 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
105 Neuroactive ligand-receptor interaction 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
106 Neuroactive ligand-receptor interaction 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
107 Neuroactive ligand-receptor interaction 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
108 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
109 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
110 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
111 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
112 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
113 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
114 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
115 Neuroactive ligand-receptor interaction 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
116 Serotonergic synapse 💬
 [1] HTR2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬
117 Serotonergic synapse 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
118 Serotonergic synapse 💬
 [1] HTR2 💬 Cisapride 💬 Cisapride [1] 13 💬
119 Serotonergic synapse 💬
 [1] HTR2 💬 Nelotanserin 💬 Nelotanserin [1]  6  💬
120 Serotonergic synapse 💬
 [1] HTR2 💬 Psilocybin 💬 Psilocybin [4]  2 ,  6 , 13, 206 💬
121 Serotonergic synapse 💬
 [1] HTR2 💬 Quetiapine fumarate 💬 Quetiapine [1]  6  💬
122 Serotonergic synapse 💬
 [1] HTR2 💬 Quetiapine 💬 Quetiapine [1]  6  💬
123 Serotonergic synapse 💬
 [1] HTR2 💬 Risperidone 💬 Risperidone [3]  8 , 156, 187 💬
124 Serotonergic synapse 💬
 [1] HTR2 💬 Agomelatine 💬 Agomelatine [1]  6  💬
125 Serotonergic synapse 💬
 [1] HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
126 Serotonergic synapse 💬
 [1] HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
127 Serotonergic synapse 💬
 [2] HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
128 Serotonergic synapse 💬
 [2] HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
129 Serotonergic synapse 💬
 [2] HTR2, HTR2 💬 Clozapine 💬 Clozapine [1]  6  💬
130 Serotonergic synapse 💬
 [2] HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
131 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
132 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
133 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
134 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone [1]  6  💬
135 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
136 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone [1]  2  💬
137 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
138 Serotonergic synapse 💬
 [3] HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬

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