Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
2 Calcium signaling pathway 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
3 Calcium signaling pathway 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
4 Calcium signaling pathway 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
5 Calcium signaling pathway 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
6 Calcium signaling pathway 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
7 Calcium signaling pathway 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
8 Calcium signaling pathway 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
9 Calcium signaling pathway 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
10 Calcium signaling pathway 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
11 Calcium signaling pathway 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
12 Calcium signaling pathway 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
13 Calcium signaling pathway 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
14 Calcium signaling pathway 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
15 Calcium signaling pathway 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
16 Calcium signaling pathway 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
17 Gap junction 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
18 Gap junction 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
19 Gap junction 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
20 Gap junction 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
21 Gap junction 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
22 Gap junction 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
23 Gap junction 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
24 Gap junction 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
25 Gap junction 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
26 Gap junction 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
27 Gap junction 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
28 Gap junction 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
29 Gap junction 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
30 Gap junction 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
31 Gap junction 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
32 Gap junction 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
33 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
34 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
35 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
36 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
37 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
38 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
39 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
40 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
41 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
42 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
43 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
44 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
45 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
46 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
47 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
48 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
49 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
50 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
51 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
52 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
53 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
54 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
55 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
56 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
57 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
58 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
59 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
60 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
61 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
62 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
63 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
64 Neuroactive ligand signaling 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
65 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
66 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
67 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
68 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
69 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
70 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
71 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
72 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
73 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
74 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
75 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
76 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
77 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
78 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
79 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
80 Neuroactive ligand-receptor interaction 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
81 Serotonergic synapse 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
82 Serotonergic synapse 💬
 [1] HTR2C 💬 Bexicaserin 💬 Bexicaserin [2] 140, 144 💬
83 Serotonergic synapse 💬
 [1] HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [2] 120, 254 💬
84 Serotonergic synapse 💬
 [1] HTR2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [2] 120, 254 💬
85 Serotonergic synapse 💬
 [1] HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
86 Serotonergic synapse 💬
 [1] HTR2C 💬 Fenfluramine hydrochloride 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
87 Serotonergic synapse 💬
 [1] HTR2C 💬 Fenfluramine 💬 Fenfluramine [6] 140, 143, 144, 145, 149, 156 💬
88 Serotonergic synapse 💬
 [1] HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
89 Serotonergic synapse 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride 💬 Lorcaserin [1] 140 💬
90 Serotonergic synapse 💬
 [1] HTR2C 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin [1] 140 💬
91 Serotonergic synapse 💬
 [1] HTR2C 💬 Mirtazapine 💬 Mirtazapine [4]  6 , 85, 97, 156 💬
92 Serotonergic synapse 💬
 [1] HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
93 Serotonergic synapse 💬
 [1] HTR2C 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
94 Serotonergic synapse 💬
 [1] HTR2C 💬 Pimavanserin tartrate 💬 Pimavanserin [1]  6  💬
95 Serotonergic synapse 💬
 [1] HTR2C 💬 Trazodone hydrochloride 💬 Trazodone [1]  2  💬
96 Serotonergic synapse 💬
 [1] HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬

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