Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Neuroactive ligand signaling 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
2 Neuroactive ligand signaling 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
3 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron 💬 Dolasetron [1] 46 💬
4 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
5 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
6 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron mesylate 💬 Dolasetron [1] 46 💬
7 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
8 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron 💬 Ramosetron [1] 97 💬
9 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Clozapine 💬 Clozapine [1]  6  💬
10 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron hydrochloride hydrate 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
11 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
12 Neuroactive ligand signaling 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
13 Serotonergic synapse 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
14 Serotonergic synapse 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
15 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron 💬 Ramosetron [1] 97 💬
16 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Clozapine 💬 Clozapine [1]  6  💬
17 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
18 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
19 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron mesylate 💬 Dolasetron [1] 46 💬
20 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
21 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron 💬 Dolasetron [1] 46 💬
22 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron hydrochloride hydrate 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
23 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
24 Serotonergic synapse 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
25 Taste transduction 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
26 Taste transduction 💬
[1] HTR3 💬 Cisapride 💬 Cisapride [1] 13 💬
27 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine 💬 Vortioxetine [2]  6 , 127 💬
28 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron 💬 Dolasetron [1] 46 💬
29 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine hydrobromide 💬 Vortioxetine [2]  6 , 127 💬
30 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron mesylate 💬 Dolasetron [1] 46 💬
31 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron hydrochloride hydrate 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
32 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
33 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron 💬 Ramosetron [1] 97 💬
34 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Mirtazapine 💬 Mirtazapine [3]  6 , 85, 97 💬
35 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron 💬 Ondansetron [5]  6 , 97, 98, 107, 231 💬
36 Taste transduction 💬
[5] HTR3, HTR3, HTR3, HTR3, HTR3 💬 Clozapine 💬 Clozapine [1]  6  💬