Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alcoholic liver disease 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Alcoholic liver disease × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
2	Chagas disease 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Chagas disease × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
3	Coronavirus disease - COVID-19 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Coronavirus disease - COVID-19 × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
4	Cytokine-cytokine receptor interaction 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Cytokine-cytokine receptor interaction × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
5	Cytosolic DNA-sensing pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Cytosolic DNA-sensing pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
6	Epstein-Barr virus infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Epstein-Barr virus infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
7	Hepatitis B 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Hepatitis B × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
8	Hepatitis C 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Hepatitis C × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
9	Herpes simplex virus 1 infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Herpes simplex virus 1 infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
10	Human cytomegalovirus infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Human cytomegalovirus infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
11	Human immunodeficiency virus 1 infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Human immunodeficiency virus 1 infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
12	Human papillomavirus infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Human papillomavirus infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
13	Influenza A 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Influenza A × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
14	JAK-STAT signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 JAK-STAT signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
15	Kaposi sarcoma-associated herpesvirus infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
16	Lipid and atherosclerosis 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Lipid and atherosclerosis × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
17	Measles 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Measles × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
18	Natural killer cell mediated cytotoxicity 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Natural killer cell mediated cytotoxicity × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
19	Necroptosis 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Necroptosis × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
20	NOD-like receptor signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 NOD-like receptor signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
21	Osteoclast differentiation 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Osteoclast differentiation × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
22	PI3K-Akt signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 PI3K-Akt signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
23	RIG-I-like receptor signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 RIG-I-like receptor signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
24	Shigellosis 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Shigellosis × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
25	TNF signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 TNF signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
26	Toll-like receptor signaling pathway 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Toll-like receptor signaling pathway × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
27	Tuberculosis 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Tuberculosis × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;
28	Yersinia infection 💬	[1] IFNB 💬 Alcoholic liver disease × Name Full Name IFNB	Dazukibart 💬 Yersinia infection × Name Other Names Dazukibart Dazukibart (USAN)	Dazukibart	[1] 50 💬 1. Alcoholic liver disease × Disease ID Name 50 Dermatomyositis;Polymyositis;

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