Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	African trypanosomiasis 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 African trypanosomiasis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 1. African trypanosomiasis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
2	African trypanosomiasis 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 African trypanosomiasis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 2. African trypanosomiasis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
3	Allograft rejection 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Allograft rejection × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 3. Allograft rejection × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
4	Allograft rejection 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Allograft rejection × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 4. Allograft rejection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
5	Amoebiasis 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Amoebiasis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 5. Amoebiasis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
6	Amoebiasis 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Amoebiasis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 6. Amoebiasis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
7	Antigen processing and presentation 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Antigen processing and presentation × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 7. Antigen processing and presentation × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
8	Antigen processing and presentation 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Antigen processing and presentation × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 8. Antigen processing and presentation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
9	Chagas disease 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Chagas disease × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 9. Chagas disease × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
10	Chagas disease 💬	[1] IFNG 💬 African trypanosomiasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Chagas disease × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 10. Chagas disease × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
11	Chagas disease 💬	[2] IFNGR1, IFNGR2 💬 Chagas disease × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Chagas disease × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 11. Chagas disease × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
12	Cytokine-cytokine receptor interaction 💬	[1] IFNG 💬 Cytokine-cytokine receptor interaction × Name Full Name IFNG interferon gamma	Emapalumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 12. Cytokine-cytokine receptor interaction × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
13	Cytokine-cytokine receptor interaction 💬	[1] IFNG 💬 Cytokine-cytokine receptor interaction × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 13. Cytokine-cytokine receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
14	Cytokine-cytokine receptor interaction 💬	[2] IFNGR1, IFNGR2 💬 Cytokine-cytokine receptor interaction × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Cytokine-cytokine receptor interaction × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 14. Cytokine-cytokine receptor interaction × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
15	Fluid shear stress and atherosclerosis 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Fluid shear stress and atherosclerosis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 15. Fluid shear stress and atherosclerosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
16	Fluid shear stress and atherosclerosis 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Fluid shear stress and atherosclerosis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 16. Fluid shear stress and atherosclerosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
17	Graft-versus-host disease 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Graft-versus-host disease × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 17. Graft-versus-host disease × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
18	Graft-versus-host disease 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Graft-versus-host disease × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 18. Graft-versus-host disease × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
19	Hepatitis C 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Hepatitis C × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 19. Hepatitis C × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
20	Hepatitis C 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Hepatitis C × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 20. Hepatitis C × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
21	Herpes simplex virus 1 infection 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Herpes simplex virus 1 infection × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 21. Herpes simplex virus 1 infection × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
22	Herpes simplex virus 1 infection 💬	[1] IFNG 💬 Fluid shear stress and atherosclerosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Herpes simplex virus 1 infection × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 22. Herpes simplex virus 1 infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
23	Herpes simplex virus 1 infection 💬	[2] IFNGR1, IFNGR2 💬 Herpes simplex virus 1 infection × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Herpes simplex virus 1 infection × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 23. Herpes simplex virus 1 infection × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
24	HIF-1 signaling pathway 💬	[1] IFNG 💬 HIF-1 signaling pathway × Name Full Name IFNG interferon gamma	Emapalumab 💬 HIF-1 signaling pathway × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 24. HIF-1 signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
25	HIF-1 signaling pathway 💬	[1] IFNG 💬 HIF-1 signaling pathway × Name Full Name IFNG interferon gamma	Fontolizumab 💬 HIF-1 signaling pathway × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 25. HIF-1 signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
26	HIF-1 signaling pathway 💬	[2] IFNGR1, IFNGR2 💬 HIF-1 signaling pathway × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 HIF-1 signaling pathway × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 26. HIF-1 signaling pathway × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
27	IL-17 signaling pathway 💬	[1] IFNG 💬 IL-17 signaling pathway × Name Full Name IFNG interferon gamma	Emapalumab 💬 IL-17 signaling pathway × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 27. IL-17 signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
28	IL-17 signaling pathway 💬	[1] IFNG 💬 IL-17 signaling pathway × Name Full Name IFNG interferon gamma	Fontolizumab 💬 IL-17 signaling pathway × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 28. IL-17 signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
29	Inflammatory bowel disease 💬	[1] IFNG 💬 IL-17 signaling pathway × Name Full Name IFNG interferon gamma	Emapalumab 💬 Inflammatory bowel disease × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 29. Inflammatory bowel disease × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
30	Inflammatory bowel disease 💬	[1] IFNG 💬 IL-17 signaling pathway × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Inflammatory bowel disease × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 30. Inflammatory bowel disease × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
31	Inflammatory bowel disease 💬	[2] IFNGR1, IFNGR2 💬 Inflammatory bowel disease × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Inflammatory bowel disease × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 31. Inflammatory bowel disease × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
32	Influenza A 💬	[1] IFNG 💬 Influenza A × Name Full Name IFNG interferon gamma	Emapalumab 💬 Influenza A × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 32. Influenza A × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
33	Influenza A 💬	[1] IFNG 💬 Influenza A × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Influenza A × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 33. Influenza A × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
34	Influenza A 💬	[2] IFNGR1, IFNGR2 💬 Influenza A × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Influenza A × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 34. Influenza A × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
35	JAK-STAT signaling pathway 💬	[1] IFNG 💬 JAK-STAT signaling pathway × Name Full Name IFNG interferon gamma	Emapalumab 💬 JAK-STAT signaling pathway × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 35. JAK-STAT signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
36	JAK-STAT signaling pathway 💬	[1] IFNG 💬 JAK-STAT signaling pathway × Name Full Name IFNG interferon gamma	Fontolizumab 💬 JAK-STAT signaling pathway × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 36. JAK-STAT signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
37	JAK-STAT signaling pathway 💬	[2] IFNGR1, IFNGR2 💬 JAK-STAT signaling pathway × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 JAK-STAT signaling pathway × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 37. JAK-STAT signaling pathway × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
38	Kaposi sarcoma-associated herpesvirus infection 💬	[1] IFNGR1 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name IFNGR1 interferon gamma receptor 1	Interferon gamma-1b 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 37. JAK-STAT signaling pathway × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
39	Leishmaniasis 💬	[1] IFNG 💬 Leishmaniasis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Leishmaniasis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 39. Leishmaniasis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
40	Leishmaniasis 💬	[1] IFNG 💬 Leishmaniasis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Leishmaniasis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 40. Leishmaniasis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
41	Leishmaniasis 💬	[2] IFNGR1, IFNGR2 💬 Leishmaniasis × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Leishmaniasis × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 41. Leishmaniasis × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
42	Malaria 💬	[1] IFNG 💬 Malaria × Name Full Name IFNG interferon gamma	Emapalumab 💬 Malaria × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 42. Malaria × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
43	Malaria 💬	[1] IFNG 💬 Malaria × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Malaria × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 43. Malaria × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
44	Natural killer cell mediated cytotoxicity 💬	[1] IFNG 💬 Malaria × Name Full Name IFNG interferon gamma	Emapalumab 💬 Natural killer cell mediated cytotoxicity × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 44. Natural killer cell mediated cytotoxicity × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
45	Natural killer cell mediated cytotoxicity 💬	[1] IFNG 💬 Malaria × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Natural killer cell mediated cytotoxicity × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 45. Natural killer cell mediated cytotoxicity × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
46	Natural killer cell mediated cytotoxicity 💬	[2] IFNGR1, IFNGR2 💬 Natural killer cell mediated cytotoxicity × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Natural killer cell mediated cytotoxicity × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 46. Natural killer cell mediated cytotoxicity × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
47	Necroptosis 💬	[1] IFNG 💬 Necroptosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Necroptosis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 47. Necroptosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
48	Necroptosis 💬	[1] IFNG 💬 Necroptosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Necroptosis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 48. Necroptosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Necroptosis 💬	[2] IFNGR1, IFNGR2 💬 Necroptosis × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Necroptosis × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 49. Necroptosis × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
50	Osteoclast differentiation 💬	[1] IFNG 💬 Osteoclast differentiation × Name Full Name IFNG interferon gamma	Emapalumab 💬 Osteoclast differentiation × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 50. Osteoclast differentiation × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
51	Osteoclast differentiation 💬	[1] IFNG 💬 Osteoclast differentiation × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Osteoclast differentiation × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 51. Osteoclast differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
52	Osteoclast differentiation 💬	[2] IFNGR1, IFNGR2 💬 Osteoclast differentiation × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Osteoclast differentiation × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 52. Osteoclast differentiation × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
53	Pathways in cancer 💬	[1] IFNG 💬 Pathways in cancer × Name Full Name IFNG interferon gamma	Emapalumab 💬 Pathways in cancer × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 53. Pathways in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
54	Pathways in cancer 💬	[1] IFNG 💬 Pathways in cancer × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Pathways in cancer × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 54. Pathways in cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
55	Pathways in cancer 💬	[2] IFNGR1, IFNGR2 💬 Pathways in cancer × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Pathways in cancer × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 55. Pathways in cancer × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
56	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] IFNG 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name IFNG interferon gamma	Emapalumab 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 56. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
57	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] IFNG 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name IFNG interferon gamma	Fontolizumab 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 57. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
58	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[2] IFNGR1, IFNGR2 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 PD-L1 expression and PD-1 checkpoint pathway in cancer × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 58. PD-L1 expression and PD-1 checkpoint pathway in cancer × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
59	Proteasome 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 Proteasome × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 59. Proteasome × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
60	Proteasome 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Proteasome × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 60. Proteasome × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
61	Rheumatoid arthritis 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 Rheumatoid arthritis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 61. Rheumatoid arthritis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
62	Rheumatoid arthritis 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Rheumatoid arthritis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 62. Rheumatoid arthritis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
63	Systemic lupus erythematosus 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 Systemic lupus erythematosus × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 63. Systemic lupus erythematosus × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
64	Systemic lupus erythematosus 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Systemic lupus erythematosus × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 64. Systemic lupus erythematosus × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
65	T cell receptor signaling pathway 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 T cell receptor signaling pathway × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 65. T cell receptor signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
66	T cell receptor signaling pathway 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 T cell receptor signaling pathway × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 66. T cell receptor signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
67	TGF-beta signaling pathway 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 TGF-beta signaling pathway × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 67. TGF-beta signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
68	TGF-beta signaling pathway 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 TGF-beta signaling pathway × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 68. TGF-beta signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
69	Th1 and Th2 cell differentiation 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Emapalumab 💬 Th1 and Th2 cell differentiation × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 69. Th1 and Th2 cell differentiation × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
70	Th1 and Th2 cell differentiation 💬	[1] IFNG 💬 Proteasome × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Th1 and Th2 cell differentiation × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 70. Th1 and Th2 cell differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
71	Th1 and Th2 cell differentiation 💬	[2] IFNGR1, IFNGR2 💬 Th1 and Th2 cell differentiation × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Th1 and Th2 cell differentiation × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 71. Th1 and Th2 cell differentiation × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
72	Th17 cell differentiation 💬	[1] IFNG 💬 Th17 cell differentiation × Name Full Name IFNG interferon gamma	Emapalumab 💬 Th17 cell differentiation × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 72. Th17 cell differentiation × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
73	Th17 cell differentiation 💬	[1] IFNG 💬 Th17 cell differentiation × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Th17 cell differentiation × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 73. Th17 cell differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
74	Th17 cell differentiation 💬	[2] IFNGR1, IFNGR2 💬 Th17 cell differentiation × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Th17 cell differentiation × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 74. Th17 cell differentiation × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
75	Toxoplasmosis 💬	[1] IFNG 💬 Toxoplasmosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Toxoplasmosis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 75. Toxoplasmosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
76	Toxoplasmosis 💬	[1] IFNG 💬 Toxoplasmosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Toxoplasmosis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 76. Toxoplasmosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
77	Toxoplasmosis 💬	[2] IFNGR1, IFNGR2 💬 Toxoplasmosis × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Toxoplasmosis × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 77. Toxoplasmosis × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
78	Tuberculosis 💬	[1] IFNG 💬 Tuberculosis × Name Full Name IFNG interferon gamma	Emapalumab 💬 Tuberculosis × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 78. Tuberculosis × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
79	Tuberculosis 💬	[1] IFNG 💬 Tuberculosis × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Tuberculosis × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 79. Tuberculosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
80	Tuberculosis 💬	[2] IFNGR1, IFNGR2 💬 Tuberculosis × Name Full Name IFNGR1 interferon gamma receptor 1 IFNGR2 interferon gamma receptor 2	Interferon gamma-1b 💬 Tuberculosis × Name Other Names Interferon gamma-1b Interferon gamma-1b (USAN/INN) Actimmune (TN)	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 80. Tuberculosis × Disease ID Name 18 Spinocerebellar degeneration;SCD; 65 Primary immunodeficiency; 85 Idiopathic interstitial pneumonia;IIPs; 228 Bronchiolitis obliterans;Obliterating bronchiolitis; 299 Cystic fibrosis; 301 Macular dystrophy; 326 Osteopetrosis;
81	Type I diabetes mellitus 💬	[1] IFNG 💬 Type I diabetes mellitus × Name Full Name IFNG interferon gamma	Emapalumab 💬 Type I diabetes mellitus × Name Other Names Emapalumab Emapalumab (USAN/INN) Emapalumab (genetical recombination) (JAN) Emapalumab-lzsg Gamifant (TN)	Emapalumab	[3] 49, 65, 107 💬 81. Type I diabetes mellitus × Disease ID Name 49 Systemic lupus erythematosus;SLE; 65 Primary immunodeficiency; 107 Juvenile idiopathic arthritis;JIA;
82	Type I diabetes mellitus 💬	[1] IFNG 💬 Type I diabetes mellitus × Name Full Name IFNG interferon gamma	Fontolizumab 💬 Type I diabetes mellitus × Name Other Names Fontolizumab Fontolizumab (USAN/INN)	Fontolizumab	[1] 46 💬 82. Type I diabetes mellitus × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;

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