Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Adherens junction × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 1. Adherens junction × Disease ID Name 232 Carney complex;CNC;
2	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Adherens junction × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 2. Adherens junction × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
3	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Adherens junction × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 2. Adherens junction × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
4	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Adherens junction × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 4. Adherens junction × Disease ID Name 49 Systemic lupus erythematosus;SLE;
5	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 AMPK signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 5. AMPK signaling pathway × Disease ID Name 232 Carney complex;CNC;
6	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 AMPK signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 6. AMPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
7	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 AMPK signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 6. AMPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
8	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 AMPK signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 8. AMPK signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
9	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Autophagy - animal × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 9. Autophagy - animal × Disease ID Name 232 Carney complex;CNC;
10	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Autophagy - animal × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 10. Autophagy - animal × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
11	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Autophagy - animal × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 10. Autophagy - animal × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
12	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Autophagy - animal × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 12. Autophagy - animal × Disease ID Name 49 Systemic lupus erythematosus;SLE;
13	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Breast cancer × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 13. Breast cancer × Disease ID Name 232 Carney complex;CNC;
14	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Breast cancer × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 14. Breast cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
15	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Breast cancer × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 14. Breast cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
16	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Breast cancer × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 16. Breast cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE;
17	Cadherin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Cadherin signaling × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 17. Cadherin signaling × Disease ID Name 232 Carney complex;CNC;
18	Cadherin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Cadherin signaling × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 18. Cadherin signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
19	Cadherin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Cadherin signaling × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 18. Cadherin signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
20	Cadherin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Cadherin signaling × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 20. Cadherin signaling × Disease ID Name 49 Systemic lupus erythematosus;SLE;
21	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Endocytosis × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 21. Endocytosis × Disease ID Name 232 Carney complex;CNC;
22	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Endocytosis × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 22. Endocytosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
23	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Endocytosis × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 22. Endocytosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
24	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Endocytosis × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 24. Endocytosis × Disease ID Name 49 Systemic lupus erythematosus;SLE;
25	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Focal adhesion × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 25. Focal adhesion × Disease ID Name 232 Carney complex;CNC;
26	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Focal adhesion × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 26. Focal adhesion × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
27	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Focal adhesion × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 26. Focal adhesion × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
28	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Focal adhesion × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 28. Focal adhesion × Disease ID Name 49 Systemic lupus erythematosus;SLE;
29	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 FoxO signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 29. FoxO signaling pathway × Disease ID Name 232 Carney complex;CNC;
30	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 FoxO signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 30. FoxO signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
31	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 FoxO signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 30. FoxO signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
32	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 FoxO signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 32. FoxO signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
33	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Glioma × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 33. Glioma × Disease ID Name 232 Carney complex;CNC;
34	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Glioma × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 34. Glioma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
35	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Glioma × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 34. Glioma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
36	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Glioma × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 36. Glioma × Disease ID Name 49 Systemic lupus erythematosus;SLE;
37	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Hepatocellular carcinoma × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 37. Hepatocellular carcinoma × Disease ID Name 232 Carney complex;CNC;
38	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Hepatocellular carcinoma × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 38. Hepatocellular carcinoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
39	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Hepatocellular carcinoma × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 38. Hepatocellular carcinoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
40	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Hepatocellular carcinoma × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 40. Hepatocellular carcinoma × Disease ID Name 49 Systemic lupus erythematosus;SLE;
41	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 HIF-1 signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 41. HIF-1 signaling pathway × Disease ID Name 232 Carney complex;CNC;
42	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 HIF-1 signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 42. HIF-1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
43	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 HIF-1 signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 42. HIF-1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
44	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 HIF-1 signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 44. HIF-1 signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
45	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Hormone signaling × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 45. Hormone signaling × Disease ID Name 232 Carney complex;CNC;
46	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Hormone signaling × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 46. Hormone signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
47	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Hormone signaling × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 46. Hormone signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
48	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Hormone signaling × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 48. Hormone signaling × Disease ID Name 49 Systemic lupus erythematosus;SLE;
49	Integrin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Integrin signaling × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 49. Integrin signaling × Disease ID Name 232 Carney complex;CNC;
50	Integrin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Integrin signaling × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 50. Integrin signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
51	Integrin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Integrin signaling × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 50. Integrin signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
52	Integrin signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Integrin signaling × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 52. Integrin signaling × Disease ID Name 49 Systemic lupus erythematosus;SLE;
53	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Long-term depression × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 53. Long-term depression × Disease ID Name 232 Carney complex;CNC;
54	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Long-term depression × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 54. Long-term depression × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
55	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Long-term depression × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 54. Long-term depression × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
56	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Long-term depression × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 56. Long-term depression × Disease ID Name 49 Systemic lupus erythematosus;SLE;
57	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Longevity regulating pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 57. Longevity regulating pathway × Disease ID Name 232 Carney complex;CNC;
58	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Longevity regulating pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 58. Longevity regulating pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
59	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Longevity regulating pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 58. Longevity regulating pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
60	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Longevity regulating pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 60. Longevity regulating pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
61	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Longevity regulating pathway - multiple species × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 61. Longevity regulating pathway - multiple species × Disease ID Name 232 Carney complex;CNC;
62	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Longevity regulating pathway - multiple species × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 62. Longevity regulating pathway - multiple species × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
63	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Longevity regulating pathway - multiple species × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 62. Longevity regulating pathway - multiple species × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
64	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Longevity regulating pathway - multiple species × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 64. Longevity regulating pathway - multiple species × Disease ID Name 49 Systemic lupus erythematosus;SLE;
65	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 MAPK signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 65. MAPK signaling pathway × Disease ID Name 232 Carney complex;CNC;
66	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 MAPK signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 66. MAPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
67	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 MAPK signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 66. MAPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
68	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 MAPK signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 68. MAPK signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
69	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Melanoma × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 69. Melanoma × Disease ID Name 232 Carney complex;CNC;
70	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Melanoma × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 70. Melanoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
71	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Melanoma × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 70. Melanoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
72	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Melanoma × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 72. Melanoma × Disease ID Name 49 Systemic lupus erythematosus;SLE;
73	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 mTOR signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 73. mTOR signaling pathway × Disease ID Name 232 Carney complex;CNC;
74	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 mTOR signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 74. mTOR signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
75	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 mTOR signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 74. mTOR signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
76	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 mTOR signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 76. mTOR signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
77	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Oocyte meiosis × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 77. Oocyte meiosis × Disease ID Name 232 Carney complex;CNC;
78	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Oocyte meiosis × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 78. Oocyte meiosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
79	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Oocyte meiosis × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 78. Oocyte meiosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
80	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Oocyte meiosis × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 80. Oocyte meiosis × Disease ID Name 49 Systemic lupus erythematosus;SLE;
81	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Ovarian steroidogenesis × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 81. Ovarian steroidogenesis × Disease ID Name 232 Carney complex;CNC;
82	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Ovarian steroidogenesis × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 82. Ovarian steroidogenesis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
83	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Ovarian steroidogenesis × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 82. Ovarian steroidogenesis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
84	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Ovarian steroidogenesis × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 84. Ovarian steroidogenesis × Disease ID Name 49 Systemic lupus erythematosus;SLE;
85	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Pathways in cancer × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 85. Pathways in cancer × Disease ID Name 232 Carney complex;CNC;
86	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Pathways in cancer × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 86. Pathways in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
87	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Pathways in cancer × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 86. Pathways in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
88	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Pathways in cancer × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 88. Pathways in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE;
89	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 PI3K-Akt signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 89. PI3K-Akt signaling pathway × Disease ID Name 232 Carney complex;CNC;
90	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 PI3K-Akt signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 90. PI3K-Akt signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
91	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 PI3K-Akt signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 90. PI3K-Akt signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
92	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 PI3K-Akt signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 92. PI3K-Akt signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
93	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Progesterone-mediated oocyte maturation × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 93. Progesterone-mediated oocyte maturation × Disease ID Name 232 Carney complex;CNC;
94	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Progesterone-mediated oocyte maturation × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 94. Progesterone-mediated oocyte maturation × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
95	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Progesterone-mediated oocyte maturation × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 94. Progesterone-mediated oocyte maturation × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
96	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Progesterone-mediated oocyte maturation × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 96. Progesterone-mediated oocyte maturation × Disease ID Name 49 Systemic lupus erythematosus;SLE;
97	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Prostate cancer × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 97. Prostate cancer × Disease ID Name 232 Carney complex;CNC;
98	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Prostate cancer × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 98. Prostate cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
99	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Prostate cancer × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 98. Prostate cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
100	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Prostate cancer × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 100. Prostate cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE;
101	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Proteoglycans in cancer × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 101. Proteoglycans in cancer × Disease ID Name 232 Carney complex;CNC;
102	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Proteoglycans in cancer × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 102. Proteoglycans in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
103	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Proteoglycans in cancer × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 102. Proteoglycans in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
104	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Proteoglycans in cancer × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 104. Proteoglycans in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE;
105	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Rap1 signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 105. Rap1 signaling pathway × Disease ID Name 232 Carney complex;CNC;
106	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Rap1 signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 106. Rap1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
107	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Rap1 signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 106. Rap1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
108	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Rap1 signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 108. Rap1 signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
109	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Ras signaling pathway × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 109. Ras signaling pathway × Disease ID Name 232 Carney complex;CNC;
110	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Ras signaling pathway × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 110. Ras signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
111	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Ras signaling pathway × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 110. Ras signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
112	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Ras signaling pathway × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 112. Ras signaling pathway × Disease ID Name 49 Systemic lupus erythematosus;SLE;
113	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 113. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 232 Carney complex;CNC;
114	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 114. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
115	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 114. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
116	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 116. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 49 Systemic lupus erythematosus;SLE;
117	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Linsitinib 💬 Transcriptional misregulation in cancer × Name Other Names Linsitinib Linsitinib	Linsitinib	[1] 232 💬 117. Transcriptional misregulation in cancer × Disease ID Name 232 Carney complex;CNC;
118	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin 💬 Transcriptional misregulation in cancer × Name Other Names Mecasermin Increlex Myotrophin	Mecasermin	[4] 96, 168, 265, 299 💬 118. Transcriptional misregulation in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
119	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Mecasermin rinfabate 💬 Transcriptional misregulation in cancer × Name Other Names Mecasermin rinfabate Iplex	Mecasermin	[4] 96, 168, 265, 299 💬 118. Transcriptional misregulation in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
120	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin-like growth factor 1 receptor isoform 1 precursor	Teprotumumab 💬 Transcriptional misregulation in cancer × Name Other Names Teprotumumab Teprotumumab-trbw Tepezza	Teprotumumab	[1] 49 💬 120. Transcriptional misregulation in cancer × Disease ID Name 49 Systemic lupus erythematosus;SLE;

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