Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Adherens junction × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 1. Adherens junction × Disease ID Name 232 Carney complex;CNC;
2	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Adherens junction × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 2. Adherens junction × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
3	Adherens junction 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Adherens junction × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 2. Adherens junction × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
4	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 AMPK signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 4. AMPK signaling pathway × Disease ID Name 232 Carney complex;CNC;
5	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 AMPK signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 5. AMPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
6	AMPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 AMPK signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 5. AMPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
7	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Autophagy - animal × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 7. Autophagy - animal × Disease ID Name 232 Carney complex;CNC;
8	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Autophagy - animal × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 8. Autophagy - animal × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
9	Autophagy - animal 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Autophagy - animal × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 8. Autophagy - animal × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
10	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Breast cancer × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 10. Breast cancer × Disease ID Name 232 Carney complex;CNC;
11	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Breast cancer × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 11. Breast cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
12	Breast cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Breast cancer × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 11. Breast cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
13	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Endocytosis × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 13. Endocytosis × Disease ID Name 232 Carney complex;CNC;
14	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Endocytosis × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 14. Endocytosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
15	Endocytosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Endocytosis × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 14. Endocytosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
16	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Focal adhesion × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 16. Focal adhesion × Disease ID Name 232 Carney complex;CNC;
17	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Focal adhesion × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 17. Focal adhesion × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
18	Focal adhesion 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Focal adhesion × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 17. Focal adhesion × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
19	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 FoxO signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 19. FoxO signaling pathway × Disease ID Name 232 Carney complex;CNC;
20	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 FoxO signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 20. FoxO signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
21	FoxO signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 FoxO signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 20. FoxO signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
22	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Glioma × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 22. Glioma × Disease ID Name 232 Carney complex;CNC;
23	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Glioma × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 23. Glioma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
24	Glioma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Glioma × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 23. Glioma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
25	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Hepatocellular carcinoma × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 25. Hepatocellular carcinoma × Disease ID Name 232 Carney complex;CNC;
26	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Hepatocellular carcinoma × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 26. Hepatocellular carcinoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
27	Hepatocellular carcinoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Hepatocellular carcinoma × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 26. Hepatocellular carcinoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
28	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 HIF-1 signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 28. HIF-1 signaling pathway × Disease ID Name 232 Carney complex;CNC;
29	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 HIF-1 signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 29. HIF-1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
30	HIF-1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 HIF-1 signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 29. HIF-1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
31	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Hormone signaling × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 31. Hormone signaling × Disease ID Name 232 Carney complex;CNC;
32	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Hormone signaling × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 32. Hormone signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
33	Hormone signaling 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Hormone signaling × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 32. Hormone signaling × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
34	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Long-term depression × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 34. Long-term depression × Disease ID Name 232 Carney complex;CNC;
35	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Long-term depression × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 35. Long-term depression × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
36	Long-term depression 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Long-term depression × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 35. Long-term depression × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
37	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Longevity regulating pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 37. Longevity regulating pathway × Disease ID Name 232 Carney complex;CNC;
38	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Longevity regulating pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 38. Longevity regulating pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
39	Longevity regulating pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Longevity regulating pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 38. Longevity regulating pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
40	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Longevity regulating pathway - multiple species × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 40. Longevity regulating pathway - multiple species × Disease ID Name 232 Carney complex;CNC;
41	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Longevity regulating pathway - multiple species × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 41. Longevity regulating pathway - multiple species × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
42	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Longevity regulating pathway - multiple species × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 41. Longevity regulating pathway - multiple species × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
43	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 MAPK signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 43. MAPK signaling pathway × Disease ID Name 232 Carney complex;CNC;
44	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 MAPK signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 44. MAPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
45	MAPK signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 MAPK signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 44. MAPK signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
46	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Melanoma × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 46. Melanoma × Disease ID Name 232 Carney complex;CNC;
47	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Melanoma × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 47. Melanoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
48	Melanoma 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Melanoma × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 47. Melanoma × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
49	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 mTOR signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 49. mTOR signaling pathway × Disease ID Name 232 Carney complex;CNC;
50	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 mTOR signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 50. mTOR signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
51	mTOR signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 mTOR signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 50. mTOR signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
52	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Oocyte meiosis × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 52. Oocyte meiosis × Disease ID Name 232 Carney complex;CNC;
53	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Oocyte meiosis × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 53. Oocyte meiosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
54	Oocyte meiosis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Oocyte meiosis × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 53. Oocyte meiosis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
55	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Ovarian steroidogenesis × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 55. Ovarian steroidogenesis × Disease ID Name 232 Carney complex;CNC;
56	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Ovarian steroidogenesis × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 56. Ovarian steroidogenesis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
57	Ovarian steroidogenesis 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Ovarian steroidogenesis × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 56. Ovarian steroidogenesis × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
58	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Pathways in cancer × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 58. Pathways in cancer × Disease ID Name 232 Carney complex;CNC;
59	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Pathways in cancer × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 59. Pathways in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
60	Pathways in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Pathways in cancer × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 59. Pathways in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
61	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 PI3K-Akt signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 61. PI3K-Akt signaling pathway × Disease ID Name 232 Carney complex;CNC;
62	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 PI3K-Akt signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 62. PI3K-Akt signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
63	PI3K-Akt signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 PI3K-Akt signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 62. PI3K-Akt signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
64	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Progesterone-mediated oocyte maturation × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 64. Progesterone-mediated oocyte maturation × Disease ID Name 232 Carney complex;CNC;
65	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Progesterone-mediated oocyte maturation × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 65. Progesterone-mediated oocyte maturation × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
66	Progesterone-mediated oocyte maturation 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Progesterone-mediated oocyte maturation × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 65. Progesterone-mediated oocyte maturation × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
67	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Prostate cancer × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 67. Prostate cancer × Disease ID Name 232 Carney complex;CNC;
68	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Prostate cancer × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 68. Prostate cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
69	Prostate cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Prostate cancer × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 68. Prostate cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
70	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Proteoglycans in cancer × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 70. Proteoglycans in cancer × Disease ID Name 232 Carney complex;CNC;
71	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Proteoglycans in cancer × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 71. Proteoglycans in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
72	Proteoglycans in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Proteoglycans in cancer × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 71. Proteoglycans in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
73	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Rap1 signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 73. Rap1 signaling pathway × Disease ID Name 232 Carney complex;CNC;
74	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Rap1 signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 74. Rap1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
75	Rap1 signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Rap1 signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 74. Rap1 signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
76	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Ras signaling pathway × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 76. Ras signaling pathway × Disease ID Name 232 Carney complex;CNC;
77	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Ras signaling pathway × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 77. Ras signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
78	Ras signaling pathway 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Ras signaling pathway × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 77. Ras signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
79	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 79. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 232 Carney complex;CNC;
80	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 80. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
81	Signaling pathways regulating pluripotency of stem cells 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Signaling pathways regulating pluripotency of stem cells × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 80. Signaling pathways regulating pluripotency of stem cells × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
82	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Linsitinib 💬 Transcriptional misregulation in cancer × Name Other Names Linsitinib Linsitinib (USAN/INN)	Linsitinib	[1] 232 💬 82. Transcriptional misregulation in cancer × Disease ID Name 232 Carney complex;CNC;
83	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin 💬 Transcriptional misregulation in cancer × Name Other Names Mecasermin Mecasermin (USAN/INN) Mecasermin (genetical recombination) (JAN) Increlex (TN) Myotrophin (TN) INCRELEX	Mecasermin	[4] 96, 168, 265, 299 💬 83. Transcriptional misregulation in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;
84	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬 Adherens junction × Name Full Name IGF1R insulin like growth factor 1 receptor	Mecasermin rinfabate 💬 Transcriptional misregulation in cancer × Name Other Names Mecasermin rinfabate Mecasermin rinfabate (USAN/INN) Iplex (TN)	Mecasermin	[4] 96, 168, 265, 299 💬 83. Transcriptional misregulation in cancer × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 265 Lipodystrophy; 299 Cystic fibrosis;CF;

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