Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
2 Adherens junction 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
3 Adherens junction 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
4 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
5 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
6 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
7 Alzheimer disease 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
8 Alzheimer disease 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
9 Alzheimer disease 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
10 AMPK signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
11 AMPK signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
12 AMPK signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
13 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
14 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
15 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
16 Diabetic cardiomyopathy 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
17 Diabetic cardiomyopathy 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
18 Diabetic cardiomyopathy 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
19 FoxO signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
20 FoxO signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
21 FoxO signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
22 HIF-1 signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
23 HIF-1 signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
24 HIF-1 signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
25 Hormone signaling 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
26 Hormone signaling 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
27 Hormone signaling 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
28 Insulin resistance 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
29 Insulin resistance 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
30 Insulin resistance 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
31 Insulin signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
32 Insulin signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
33 Insulin signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
34 Longevity regulating pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
35 Longevity regulating pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
36 Longevity regulating pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
37 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
38 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
39 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
40 MAPK signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
41 MAPK signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
42 MAPK signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
43 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
44 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
45 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
46 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
47 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
48 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
49 Ovarian steroidogenesis 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
50 Ovarian steroidogenesis 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
51 Ovarian steroidogenesis 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
52 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
53 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
54 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
55 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
56 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
57 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
58 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
59 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
60 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
61 Ras signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
62 Ras signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
63 Ras signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
64 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
65 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
66 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
67 Type II diabetes mellitus 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
68 Type II diabetes mellitus 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [2] 35, 299 💬
69 Type II diabetes mellitus 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬

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