Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
2 Calcium signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
3 Calcium signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
4 Calcium signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
5 Calcium signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
6 Calcium signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
7 Calcium signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
8 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
9 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
10 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
11 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
12 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
13 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
14 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
15 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
16 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
17 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
18 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
19 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
20 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
21 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
22 Focal adhesion 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
23 Focal adhesion 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
24 Focal adhesion 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
25 Focal adhesion 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
26 Focal adhesion 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
27 Focal adhesion 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
28 Focal adhesion 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
29 MAPK signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
30 MAPK signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
31 MAPK signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
32 MAPK signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
33 MAPK signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
34 MAPK signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
35 MAPK signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
36 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
37 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
38 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
39 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
40 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
41 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
42 PI3K-Akt signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
43 Proteoglycans in cancer 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
44 Proteoglycans in cancer 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
45 Proteoglycans in cancer 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
46 Proteoglycans in cancer 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
47 Proteoglycans in cancer 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
48 Proteoglycans in cancer 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
49 Proteoglycans in cancer 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
50 Rap1 signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
51 Rap1 signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
52 Rap1 signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
53 Rap1 signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
54 Rap1 signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
55 Rap1 signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
56 Rap1 signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
57 Ras signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
58 Ras signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
59 Ras signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
60 Ras signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
61 Ras signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
62 Ras signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
63 Ras signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
64 VEGF signaling pathway 💬
 [1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
65 VEGF signaling pathway 💬
 [1] KDR 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
66 VEGF signaling pathway 💬
 [1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
67 VEGF signaling pathway 💬
 [1] KDR 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
68 VEGF signaling pathway 💬
 [1] KDR 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
69 VEGF signaling pathway 💬
 [1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
70 VEGF signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬

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