Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
2 Acute myeloid leukemia 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
3 Acute myeloid leukemia 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
4 Acute myeloid leukemia 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
5 Acute myeloid leukemia 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6 Acute myeloid leukemia 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
7 Acute myeloid leukemia 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
8 Acute myeloid leukemia 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
9 Acute myeloid leukemia 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
10 Acute myeloid leukemia 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
11 Acute myeloid leukemia 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
12 Acute myeloid leukemia 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
13 Acute myeloid leukemia 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
14 Breast cancer 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
15 Breast cancer 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
16 Breast cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
17 Breast cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
18 Breast cancer 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
19 Breast cancer 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
20 Breast cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
21 Breast cancer 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
22 Breast cancer 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
23 Breast cancer 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
24 Breast cancer 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
25 Breast cancer 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
26 Breast cancer 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
27 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
28 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
29 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
30 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
31 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
32 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
33 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
34 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
35 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
36 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
37 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
38 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
39 Central carbon metabolism in cancer 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
40 Hematopoietic cell lineage 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
41 Hematopoietic cell lineage 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
42 Hematopoietic cell lineage 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
43 Hematopoietic cell lineage 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
44 Hematopoietic cell lineage 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
45 Hematopoietic cell lineage 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
46 Hematopoietic cell lineage 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
47 Hematopoietic cell lineage 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
48 Hematopoietic cell lineage 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
49 Hematopoietic cell lineage 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
50 Hematopoietic cell lineage 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
51 Hematopoietic cell lineage 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
52 Hematopoietic cell lineage 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
53 MAPK signaling pathway 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
54 MAPK signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
55 MAPK signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
56 MAPK signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
57 MAPK signaling pathway 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
58 MAPK signaling pathway 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
59 MAPK signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
60 MAPK signaling pathway 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
61 MAPK signaling pathway 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
62 MAPK signaling pathway 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
63 MAPK signaling pathway 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
64 MAPK signaling pathway 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
65 MAPK signaling pathway 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
66 Melanogenesis 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
67 Melanogenesis 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
68 Melanogenesis 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
69 Melanogenesis 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
70 Melanogenesis 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
71 Melanogenesis 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
72 Melanogenesis 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
73 Melanogenesis 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
74 Melanogenesis 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
75 Melanogenesis 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
76 Melanogenesis 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
77 Melanogenesis 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
78 Melanogenesis 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
79 Pathways in cancer 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
80 Pathways in cancer 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
81 Pathways in cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
82 Pathways in cancer 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
83 Pathways in cancer 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
84 Pathways in cancer 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
85 Pathways in cancer 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
86 Pathways in cancer 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
87 Pathways in cancer 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
88 Pathways in cancer 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
89 Pathways in cancer 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
90 Pathways in cancer 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
91 Pathways in cancer 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
92 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
93 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
94 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
95 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
96 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
97 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
98 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
99 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
100 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
101 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
102 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
103 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
104 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
105 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
106 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
107 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
108 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
109 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
110 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
111 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
112 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
113 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
114 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
115 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
116 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
117 PI3K-Akt signaling pathway 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
118 Rap1 signaling pathway 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
119 Rap1 signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
120 Rap1 signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
121 Rap1 signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
122 Rap1 signaling pathway 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
123 Rap1 signaling pathway 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
124 Rap1 signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
125 Rap1 signaling pathway 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
126 Rap1 signaling pathway 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
127 Rap1 signaling pathway 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
128 Rap1 signaling pathway 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
129 Rap1 signaling pathway 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
130 Rap1 signaling pathway 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
131 Ras signaling pathway 💬
 [1] KIT 💬 Catequentinib 💬 Anlotinib [1] 85 💬
132 Ras signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
133 Ras signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
134 Ras signaling pathway 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
135 Ras signaling pathway 💬
 [1] KIT 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
136 Ras signaling pathway 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
137 Ras signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
138 Ras signaling pathway 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
139 Ras signaling pathway 💬
 [1] KIT 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
140 Ras signaling pathway 💬
 [1] KIT 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
141 Ras signaling pathway 💬
 [1] KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
142 Ras signaling pathway 💬
 [1] KIT 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
143 Ras signaling pathway 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬

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