Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
2 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
3 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
4 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
5 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
6 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
7 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
8 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
9 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
10 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
11 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
12 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
13 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
14 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
15 cGMP-PKG signaling pathway 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
16 Hormone signaling 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
17 Hormone signaling 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
18 Hormone signaling 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
19 Hormone signaling 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
20 Hormone signaling 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
21 Hormone signaling 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
22 Hormone signaling 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
23 Hormone signaling 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
24 Hormone signaling 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
25 Hormone signaling 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
26 Hormone signaling 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
27 Hormone signaling 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
28 Hormone signaling 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
29 Hormone signaling 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
30 Hormone signaling 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
31 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
32 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
33 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
34 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
35 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
36 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
37 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
38 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
39 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
40 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
41 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
42 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
43 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
44 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
45 Neuroactive ligand signaling 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
46 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
47 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
48 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
49 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
50 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
51 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
52 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
53 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
54 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
55 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
56 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
57 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
58 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
59 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
60 Neuroactive ligand-receptor interaction 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
61 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
62 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
63 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
64 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
65 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
66 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
67 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
68 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
69 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
70 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
71 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
72 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
73 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
74 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
75 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬

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