Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Hormone signaling 💬
[1] OPRK1 💬 Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
2 Hormone signaling 💬
[1] OPRK1 💬 Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
3 Hormone signaling 💬
[1] OPRK1 💬 Dezocine 💬 Dezocine [1] 46 💬
4 Hormone signaling 💬
[1] OPRK1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
5 Hormone signaling 💬
[1] OPRK1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
6 Hormone signaling 💬
[1] OPRK1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
7 Hormone signaling 💬
[1] OPRK1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
8 Hormone signaling 💬
[1] OPRK1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
9 Hormone signaling 💬
[1] OPRK1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
10 Hormone signaling 💬
[1] OPRK1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
11 Hormone signaling 💬
[1] OPRK1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
12 Hormone signaling 💬
[1] OPRK1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
13 Hormone signaling 💬
[1] OPRK1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
14 Hormone signaling 💬
[1] OPRK1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
15 Hormone signaling 💬
[1] OPRK1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
16 Hormone signaling 💬
[1] OPRK1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
17 Hormone signaling 💬
[1] OPRK1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
18 Hormone signaling 💬
[1] OPRK1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
19 Hormone signaling 💬
[1] OPRK1 💬 Trimebutine maleate 💬 Trimebutine [1] 51 💬
20 Hormone signaling 💬
[1] OPRK1 💬 Trimebutine 💬 Trimebutine [1] 51 💬
21 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
22 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
23 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Dezocine 💬 Dezocine [1] 46 💬
24 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
25 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
26 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
27 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
28 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
29 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
30 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
31 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
32 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
33 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
34 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
35 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
36 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
37 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
38 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
39 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Trimebutine maleate 💬 Trimebutine [1] 51 💬
40 Neuroactive ligand signaling 💬
[1] OPRK1 💬 Trimebutine 💬 Trimebutine [1] 51 💬
41 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
42 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
43 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Dezocine 💬 Dezocine [1] 46 💬
44 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
45 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
46 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Nalbuphine hydrochloride 💬 Nalbuphine [1] 85 💬
47 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
48 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Nalmefene hydrochloride 💬 Nalmefene [2]  6 , 93 💬
49 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Nalmefene 💬 Nalmefene [2]  6 , 93 💬
50 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Nalmefene hydrochloride hydrate 💬 Nalmefene [2]  6 , 93 💬
51 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Naloxone hydrochloride 💬 Naloxone [2]  6 , 226 💬
52 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
53 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Naloxone hydrochloride dihydrate 💬 Naloxone [2]  6 , 226 💬
54 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Naltrexone hydrochloride 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
55 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Naltrexone 💬 Naltrexone [12]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
56 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Oxycodone hydrochloride 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
57 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Oxycodone terephthalate 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
58 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Oxycodone 💬 Oxycodone [6]  6 , 46, 70, 226, 231, 298 💬
59 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Trimebutine maleate 💬 Trimebutine [1] 51 💬
60 Neuroactive ligand-receptor interaction 💬
[1] OPRK1 💬 Trimebutine 💬 Trimebutine [1] 51 💬