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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Calcium signaling pathway 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Calcium signaling pathway 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Calcium signaling pathway 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Calcium signaling pathway 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

cAMP signaling pathway 💬

[1] PDE10 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Cushing syndrome 💬

[1] PDE11 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Cushing syndrome 💬

[1] PDE11 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Cushing syndrome 💬

[1] PDE11 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Cushing syndrome 💬

[1] PDE11 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Cushing syndrome 💬

[1] PDE11 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Cushing syndrome 💬

[1] PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Cushing syndrome 💬

[1] PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Cushing syndrome 💬

[1] PDE11 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Morphine addiction 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Morphine addiction 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Morphine addiction 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Morphine addiction 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Olfactory transduction 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Olfactory transduction 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Olfactory transduction 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Olfactory transduction 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Purine metabolism 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Purine metabolism 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Purine metabolism 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Purine metabolism 💬

[5] PDE1, PDE1, PDE1, PDE10, PDE11 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Renin secretion 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Renin secretion 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Renin secretion 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Bucladesine 💬

Bucladesine

[1] 246 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline sodium glycinate 💬

Theophylline

[2] 236, 299 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline 💬

Aminophylline

[1] 63 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate hydrochloride 💬

Flavoxate

[1] 226 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Flavoxate 💬

Flavoxate

[1] 226 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Aminophylline dihydrate 💬

Aminophylline

[1] 63 💬

Renin secretion 💬

[3] PDE1, PDE1, PDE1 💬

Theophylline 💬

Theophylline

[2] 236, 299 💬

Taste transduction 💬

[1] PDE1 💬

Caffeine 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Taste transduction 💬

[1] PDE1 💬

Caffeine hydrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;

Taste transduction 💬

[1] PDE1 💬

Caffeine citrate 💬

Caffeine

[8] 2 , 6 , 13, 21, 46, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
21	Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV;
96	Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
97	Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Lipodystrophy;