Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
2 Calcium signaling pathway 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
3 Calcium signaling pathway 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
4 Calcium signaling pathway 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
5 Calcium signaling pathway 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
6 Calcium signaling pathway 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
7 Calcium signaling pathway 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
8 Metabolic pathways 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
9 Metabolic pathways 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
10 Metabolic pathways 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
11 Metabolic pathways 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
12 Metabolic pathways 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
13 Metabolic pathways 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
14 Metabolic pathways 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
15 Morphine addiction 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
16 Morphine addiction 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
17 Morphine addiction 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
18 Morphine addiction 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
19 Morphine addiction 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
20 Morphine addiction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
21 Morphine addiction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
22 Olfactory transduction 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
23 Olfactory transduction 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
24 Olfactory transduction 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
25 Olfactory transduction 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
26 Olfactory transduction 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
27 Olfactory transduction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
28 Olfactory transduction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
29 Purine metabolism 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
30 Purine metabolism 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
31 Purine metabolism 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
32 Purine metabolism 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
33 Purine metabolism 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
34 Purine metabolism 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
35 Purine metabolism 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
36 Renin secretion 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
37 Renin secretion 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
38 Renin secretion 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
39 Renin secretion 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
40 Renin secretion 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
41 Renin secretion 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
42 Renin secretion 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
43 Taste transduction 💬
 [1] PDE1B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
44 Taste transduction 💬
 [1] PDE1B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
45 Taste transduction 💬
 [1] PDE1B 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
46 Taste transduction 💬
 [1] PDE1B 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
47 Taste transduction 💬
 [1] PDE1B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
48 Taste transduction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
49 Taste transduction 💬
 [1] PDE1B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬

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