Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
2 Acute myeloid leukemia 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Alcoholism 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
4 Alcoholism 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
5 Alzheimer disease 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
6 Alzheimer disease 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
7 Apelin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
8 Apelin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
9 Apoptosis 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
10 Apoptosis 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
11 Autophagy - animal 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
12 Autophagy - animal 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
13 Axon guidance 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
14 Axon guidance 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
15 B cell receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
16 B cell receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
17 Bladder cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
18 Bladder cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
19 Breast cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
20 Breast cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
21 C-type lectin receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
22 C-type lectin receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
23 cAMP signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
24 cAMP signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
25 Cellular senescence 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
26 Cellular senescence 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
27 Central carbon metabolism in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
28 Central carbon metabolism in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
29 cGMP-PKG signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
30 cGMP-PKG signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
31 Chemical carcinogenesis - reactive oxygen species 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
32 Chemical carcinogenesis - reactive oxygen species 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
33 Chemical carcinogenesis - receptor activation 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
34 Chemical carcinogenesis - receptor activation 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
35 Chemokine signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
36 Chemokine signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
37 Choline metabolism in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
38 Choline metabolism in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
39 Chronic myeloid leukemia 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
40 Chronic myeloid leukemia 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
41 Colorectal cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
42 Colorectal cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
43 Endometrial cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
44 Endometrial cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
45 ErbB signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
46 ErbB signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
47 Estrogen signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
48 Estrogen signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
49 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
50 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
51 Fc gamma R-mediated phagocytosis 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
52 Fc gamma R-mediated phagocytosis 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
53 Focal adhesion 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
54 Focal adhesion 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
55 FoxO signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
56 FoxO signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
57 Gap junction 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
58 Gap junction 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
59 Gastric cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
60 Gastric cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
61 Glioma 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
62 Glioma 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
63 GnRH secretion 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
64 GnRH secretion 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
65 GnRH signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
66 GnRH signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
67 Growth hormone synthesis, secretion and action 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
68 Growth hormone synthesis, secretion and action 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
69 Hepatitis B 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
70 Hepatitis B 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
71 Hepatitis C 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
72 Hepatitis C 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
73 Hepatocellular carcinoma 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
74 Hepatocellular carcinoma 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
75 Human cytomegalovirus infection 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
76 Human cytomegalovirus infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
77 Human immunodeficiency virus 1 infection 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
78 Human immunodeficiency virus 1 infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
79 Human papillomavirus infection 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
80 Human papillomavirus infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
81 Influenza A 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
82 Influenza A 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
83 Insulin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
84 Insulin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
85 JAK-STAT signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
86 JAK-STAT signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
87 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
88 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
89 Long-term depression 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
90 Long-term depression 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
91 Long-term potentiation 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
92 Long-term potentiation 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
93 MAPK signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
94 MAPK signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
95 Melanogenesis 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
96 Melanogenesis 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
97 Melanoma 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
98 Melanoma 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
99 MicroRNAs in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
100 MicroRNAs in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
101 mTOR signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
102 mTOR signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
103 Natural killer cell mediated cytotoxicity 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
104 Natural killer cell mediated cytotoxicity 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
105 Neurotrophin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
106 Neurotrophin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
107 Neutrophil extracellular trap formation 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
108 Neutrophil extracellular trap formation 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
109 Non-small cell lung cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
110 Non-small cell lung cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
111 Oxytocin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
112 Oxytocin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
113 Pancreatic cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
114 Pancreatic cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
115 Parathyroid hormone synthesis, secretion and action 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
116 Parathyroid hormone synthesis, secretion and action 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
117 Pathways in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
118 Pathways in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
119 Pathways of neurodegeneration - multiple diseases 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
120 Pathways of neurodegeneration - multiple diseases 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
121 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
122 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
123 Phospholipase D signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
124 Phospholipase D signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
125 PI3K-Akt signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
126 PI3K-Akt signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
127 Progesterone-mediated oocyte maturation 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
128 Progesterone-mediated oocyte maturation 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
129 Prolactin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
130 Prolactin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
131 Prostate cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
132 Prostate cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
133 Proteoglycans in cancer 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
134 Proteoglycans in cancer 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
135 Rap1 signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
136 Rap1 signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
137 Ras signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
138 Ras signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
139 Regulation of actin cytoskeleton 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
140 Regulation of actin cytoskeleton 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
141 Relaxin signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
142 Relaxin signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
143 Renal cell carcinoma 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
144 Renal cell carcinoma 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
145 Salmonella infection 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
146 Salmonella infection 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
147 Serotonergic synapse 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
148 Serotonergic synapse 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
149 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
150 Signaling pathways regulating pluripotency of stem cells 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
151 Sphingolipid signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
152 Sphingolipid signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
153 T cell receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
154 T cell receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
155 Thyroid hormone signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
156 Thyroid hormone signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
157 Tuberculosis 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
158 Tuberculosis 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
159 Vascular smooth muscle contraction 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
160 Vascular smooth muscle contraction 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
161 VEGF signaling pathway 💬
 [1] RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
162 VEGF signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬

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