Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
2 Adherens junction 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
3 Adherens junction 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
4 Adherens junction 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
5 Axon guidance 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
6 Axon guidance 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
7 Axon guidance 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
8 Axon guidance 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
9 Cadherin signaling 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
10 Cadherin signaling 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
11 Cadherin signaling 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
12 Cadherin signaling 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
13 cAMP signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
14 cAMP signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
15 cAMP signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
16 cAMP signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
17 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
18 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
19 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
20 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
21 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
22 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
23 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
24 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
25 Focal adhesion 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
26 Focal adhesion 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
27 Focal adhesion 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
28 Focal adhesion 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
29 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
30 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
31 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
32 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
33 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
34 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
35 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
36 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
37 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
38 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
39 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
40 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
41 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
42 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
43 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
44 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
45 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
46 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
47 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
48 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
49 Pathways in cancer 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
50 Pathways in cancer 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
51 Pathways in cancer 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
52 Pathways in cancer 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
53 Platelet activation 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
54 Platelet activation 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
55 Platelet activation 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
56 Platelet activation 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
57 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
58 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
59 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
60 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
61 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
62 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
63 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
64 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
65 Salmonella infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
66 Salmonella infection 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
67 Salmonella infection 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
68 Salmonella infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
69 Shigellosis 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
70 Shigellosis 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
71 Shigellosis 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
72 Shigellosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
73 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
74 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
75 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
76 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
77 Tight junction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
78 Tight junction 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
79 Tight junction 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
80 Tight junction 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
81 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
82 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
83 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
84 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
85 Wnt signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
86 Wnt signaling pathway 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
87 Wnt signaling pathway 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
88 Wnt signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
89 Yersinia infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
90 Yersinia infection 💬
 [1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
91 Yersinia infection 💬
 [1] ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
92 Yersinia infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬

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