Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Axon guidance 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
2 Axon guidance 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
3 cAMP signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
4 cAMP signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
5 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
6 cGMP-PKG signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
7 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
8 Chemokine signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
9 Focal adhesion 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
10 Focal adhesion 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
11 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
12 Human cytomegalovirus infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
13 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
14 Leukocyte transendothelial migration 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
15 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
16 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
17 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
18 Oxytocin signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
19 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
20 Pathogenic Escherichia coli infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
21 Pathways in cancer 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
22 Pathways in cancer 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
23 Platelet activation 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
24 Platelet activation 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
25 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
26 Proteoglycans in cancer 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
27 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
28 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
29 Salmonella infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
30 Salmonella infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
31 Shigellosis 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
32 Shigellosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
33 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
34 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
35 Tight junction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
36 Tight junction 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
37 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
38 Vascular smooth muscle contraction 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
39 Wnt signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
40 Wnt signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
41 Yersinia infection 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬
42 Yersinia infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬

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