Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 B cell receptor signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
2 B cell receptor signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
3 B cell receptor signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
4 C-type lectin receptor signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
5 C-type lectin receptor signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
6 C-type lectin receptor signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
7 Coronavirus disease - COVID-19 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
8 Coronavirus disease - COVID-19 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
9 Coronavirus disease - COVID-19 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
10 Epstein-Barr virus infection 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
11 Epstein-Barr virus infection 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
12 Epstein-Barr virus infection 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
13 Fc epsilon RI signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
14 Fc epsilon RI signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
15 Fc epsilon RI signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
16 Fc gamma R-mediated phagocytosis 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
17 Fc gamma R-mediated phagocytosis 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
18 Fc gamma R-mediated phagocytosis 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
19 Herpes simplex virus 1 infection 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
20 Herpes simplex virus 1 infection 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
21 Herpes simplex virus 1 infection 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
22 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
23 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
24 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
25 Natural killer cell mediated cytotoxicity 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
26 Natural killer cell mediated cytotoxicity 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
27 Natural killer cell mediated cytotoxicity 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
28 Neutrophil extracellular trap formation 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
29 Neutrophil extracellular trap formation 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
30 Neutrophil extracellular trap formation 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
31 NF-kappa B signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
32 NF-kappa B signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
33 NF-kappa B signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
34 Osteoclast differentiation 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
35 Osteoclast differentiation 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
36 Osteoclast differentiation 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
37 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
38 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
39 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
40 PI3K-Akt signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
41 PI3K-Akt signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
42 PI3K-Akt signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
43 Platelet activation 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
44 Platelet activation 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
45 Platelet activation 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
46 Tuberculosis 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
47 Tuberculosis 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
48 Tuberculosis 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬
49 Viral carcinogenesis 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
50 Viral carcinogenesis 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
51 Viral carcinogenesis 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬

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