Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Adipocytokine signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
2	Alcoholic liver disease 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Alcoholic liver disease × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
3	Alzheimer disease 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Alzheimer disease × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
4	Amyotrophic lateral sclerosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Amyotrophic lateral sclerosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
5	Apoptosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Apoptosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
6	Apoptosis - multiple species 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Apoptosis - multiple species × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
7	Chagas disease 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Chagas disease × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
8	Coronavirus disease 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Coronavirus disease × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
9	Cytokine-cytokine receptor interaction 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Cytokine-cytokine receptor interaction × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
10	Fluid shear stress and atherosclerosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Fluid shear stress and atherosclerosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
11	Hepatitis C 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Hepatitis C × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
12	Herpes simplex virus 1 infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Herpes simplex virus 1 infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
13	Human cytomegalovirus infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Human cytomegalovirus infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
14	Human immunodeficiency virus 1 infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Human immunodeficiency virus 1 infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
15	Human papillomavirus infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Human papillomavirus infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
16	Human T-cell leukemia virus 1 infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Human T-cell leukemia virus 1 infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
17	Influenza A 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Influenza A × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
18	Insulin resistance 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Insulin resistance × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
19	Kaposi sarcoma-associated herpesvirus infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
20	Lipid and atherosclerosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Lipid and atherosclerosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
21	MAPK signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 MAPK signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
22	mTOR signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 mTOR signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
23	Necroptosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Necroptosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
24	NF-kappa B signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 NF-kappa B signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
25	Non-alcoholic fatty liver disease 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Non-alcoholic fatty liver disease × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
26	Osteoclast differentiation 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Osteoclast differentiation × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
27	Pathogenic Escherichia coli infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Pathogenic Escherichia coli infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
28	Pathways of neurodegeneration - multiple diseases 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
29	Salmonella infection 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Salmonella infection × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
30	Shigellosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Shigellosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
31	Sphingolipid signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Sphingolipid signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
32	TNF signaling pathway 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 TNF signaling pathway × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
33	Toxoplasmosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Toxoplasmosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
34	Tuberculosis 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Tuberculosis × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
35	Viral protein interaction with cytokine and cytokine receptor 💬	[1] TNFRSF1A 💬 Adipocytokine signaling pathway × Name Full Name TNFRSF1A tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	Balinatunfib 💬 Viral protein interaction with cytokine and cytokine receptor × Name Other Names Balinatunfib Balinatunfib	Balinatunfib	[2] 96, 97 💬 1. Adipocytokine signaling pathway × Disease ID Name 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;

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