Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Allograft rejection 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
2 Allograft rejection 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
3 Allograft rejection 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
4 Asthma 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
5 Asthma 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
6 Asthma 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
7 Autoimmune thyroid disease 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
8 Autoimmune thyroid disease 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
9 Autoimmune thyroid disease 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
10 Cell adhesion molecules 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
11 Cell adhesion molecules 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
12 Cell adhesion molecules 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
13 Cytokine-cytokine receptor interaction 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
14 Cytokine-cytokine receptor interaction 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
15 Cytokine-cytokine receptor interaction 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
16 Epstein-Barr virus infection 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
17 Epstein-Barr virus infection 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
18 Epstein-Barr virus infection 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
19 Human T-cell leukemia virus 1 infection 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
20 Human T-cell leukemia virus 1 infection 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
21 Human T-cell leukemia virus 1 infection 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
22 Intestinal immune network for IgA production 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
23 Intestinal immune network for IgA production 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
24 Intestinal immune network for IgA production 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
25 Lipid and atherosclerosis 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
26 Lipid and atherosclerosis 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
27 Lipid and atherosclerosis 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
28 Malaria 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
29 Malaria 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
30 Malaria 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
31 NF-kappa B signaling pathway 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
32 NF-kappa B signaling pathway 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
33 NF-kappa B signaling pathway 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
34 Primary immunodeficiency 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
35 Primary immunodeficiency 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
36 Primary immunodeficiency 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
37 Systemic lupus erythematosus 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
38 Systemic lupus erythematosus 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
39 Systemic lupus erythematosus 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
40 Toll-like receptor signaling pathway 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
41 Toll-like receptor signaling pathway 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
42 Toll-like receptor signaling pathway 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
43 Toxoplasmosis 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
44 Toxoplasmosis 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
45 Toxoplasmosis 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
46 Transcriptional misregulation in cancer 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
47 Transcriptional misregulation in cancer 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
48 Transcriptional misregulation in cancer 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
49 Viral myocarditis 💬
 [1] TNFRSF5 💬 Bleselumab 💬 Bleselumab [1] 222 💬
50 Viral myocarditis 💬
 [1] TNFRSF5 💬 Iscalimab 💬 Iscalimab [2] 49, 53 💬
51 Viral myocarditis 💬
 [1] TNFRSF5 💬 Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬

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