Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
2 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
3 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
4 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
5 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
6 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
7 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
8 Alzheimer disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
9 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
10 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
11 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
12 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
13 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
14 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
15 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
16 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
17 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
18 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
19 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
20 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
21 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
22 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
23 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
24 Gap junction 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
25 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
26 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
27 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
28 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
29 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
30 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
31 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
32 Huntington disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
33 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
34 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
35 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
36 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
37 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
38 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
39 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
40 Motor proteins 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
41 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
42 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
43 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
44 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
45 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
46 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
47 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
48 Parkinson disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
49 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
50 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
51 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
52 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
53 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
54 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
55 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
56 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
57 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
58 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
59 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
60 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
61 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
62 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
63 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
64 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
65 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
66 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
67 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
68 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
69 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
70 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
71 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
72 Phagosome 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
73 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
74 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
75 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
76 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
77 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬
78 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
79 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
80 Prion disease 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
81 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine [3] 26, 34, 331 💬
82 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine [3] 34, 63, 65 💬
83 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine [3] 34, 63, 65 💬
84 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel [1] 85 💬
85 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin [1] 28 💬
86 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine [3] 26, 34, 331 💬
87 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine [9]  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
88 Salmonella infection 💬
 [9] TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin [2] 49, 51 💬

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