86. 肺動脈性肺高血圧症 Disease details / Clinical trials / Drug dev / DR info

10-nitro-9(E)-octadec-9-enoic acid
   Complexa Inc.
      2019   Phase 2   EUCTR2019-002414-40-GB   United Kingdom;United States
11C-acetate
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
120 MG sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2011   Phase 1   NCT01409122   United States
129XE hyperpolarized
   Bastiaan Driehuys
      2025   Phase 2   NCT06351345   United States
      2024   Phase 2   NCT06104228   United States
      2021   Phase 2   NCT04991454   United States
15 MG sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2011   Phase 1   NCT01409122   United States
150MG CXA-10
   Complexa, Inc.
      2018   Phase 2   NCT03449524   United Kingdom;United States
18F-fgln PET imaging
   Stephen Y. Chan
      2022   Early Phase 1   NCT05452889   United States
2-(4-[5,6-diphenylpyrazin-2-YL)(isopropyl)amino]butoxy)-N-(methylsulfonyl)actamide
   Actelion Pharmaceuticals Ltd
      2008   -   EUCTR2007-003328-39-HU   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   Nippon Shinyaku Co., LTD
      2009   -   EUCTR2007-003328-39-AT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-003328-39-FR   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
2-hoba
   Vanderbilt University Medical Center
      2025   Phase 2   NCT06176118   -
2-{4-[(5,6-diphenylpyrazin-2-YL)(isopropyl)amino]butoxy}-N-(methylsulfonyl) acetamide
   Actelion Pharmaceuticals Ltd
      2008   Phase 2   EUCTR2007-006453-12-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   Nippon Shinyaku Co., Ltd.
      2008   Phase 2   EUCTR2007-006453-12-FR   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
20 MG/ML treprostinil
   AOP Orphan Pharmaceuticals GmbH
      2021   Phase 2   EUCTR2021-004002-21-AT   Austria
25% MTD sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2011   Phase 1   NCT01409122   United States
400 MG BIA 5-1058
   Bial - Portela C S.A.
      2017   Phase 1   NCT04991181   Netherlands
45 MG sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2011   Phase 1   NCT01409122   United States
4au76
   GlaxoSmithKline Research and Development Limited
      2011   -   EUCTR2011-002943-92-NL   Canada;Netherlands;United States
6-minute walk distance (6MWD) test
   University of Zurich
      2023   -   NCT06003244   Switzerland
6-minute walk distance (6MWD) test ON ambient AIR
   University of Zurich
      2024   -   NCT06384534   Switzerland
6-minute walk distance test with supplemental oxygen
   University of Zurich
      2024   -   NCT06384534   Switzerland
66215-101
   ICIN
      2010   -   EUCTR2008-004533-21-NL   Netherlands
6R-BH4
   Vanderbilt University
      2008   Phase 1   NCT00435331   United States
75MG CXA-10
   Complexa, Inc.
      2018   Phase 2   NCT03449524   United Kingdom;United States
90 MG sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2011   Phase 1   NCT01409122   United States
Access program - sildenafil citrate, viagra, revatio
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2011   -   NCT01582438   India
ACE-011
   ACCELERON PHARMA INC.
      2022   Phase 3   EUCTR2021-001498-21-IT   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-000199-12-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
   Acceleron Pharma Inc.
      2022   Phase 2   EUCTR2021-003020-32-ES   Belgium;Canada;France;Germany;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2022   Phase 3   EUCTR2021-000199-12-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 2   EUCTR2021-003020-32-FR   Belgium;Canada;France;Germany;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-FR   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-ES   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-FR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-ES   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-FR   Argentina;Australia;Austria;Belgium;Brazil;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-ES   Argentina;Australia;Austria;Belgium;Brazil;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 2   EUCTR2017-004738-27-BE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-GB   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-ES   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-DE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2021-000199-12-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2021-000199-12-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
ACE-011 / ??-7962
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      -   Phase 3   EUCTR2020-005061-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
ACE-011 / MK - 7962
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
ACE-011 / MK-7962
   Acceleron Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2021-001498-21-DE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-NL   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-BE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron, Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
ACE-011/ MK-7962
   Acceleron Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2021-001498-21-DE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
Acetaminophen
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
ACT - 064992
   Actelion Pharmaceuticals Ltd.
      2008   -   EUCTR2007-002440-14-IT   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
ACT-050089
   Actelion Pharmaceuticals Ltd.
      2009   Phase 2   EUCTR2009-012450-20-FR   France
   Idorsia Pharmaceuticals Ltd.
      2010   Phase 2   NCT01094067   France;Japan;United States
ACT-064992
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   ACTELION Pharmaceuticals France
      2015   Phase 4   EUCTR2015-002078-19-FR   France
   ACTELION Pharmaceuticals Ltd
      2017   Phase 3   EUCTR2016-001062-28-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Finland;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
      2017   Phase 3   EUCTR2016-001062-28-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2016-001062-28-FR   Australia;Austria;Canada;China;Colombia;Finland;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2014   Phase 3   EUCTR2013-003489-15-ES   Italy;Spain
      2014   -   EUCTR2013-003462-14-ES   Spain
      2013   Phase 3   EUCTR2013-003489-15-IT   Italy;Spain
      2013   Phase 3   EUCTR2013-003462-14-IT   Italy;Spain
   ACTELION Pharmacteuticals Ltd.
      -   Phase 1   EUCTR2022-002754-74-PL   Germany;Poland
      -   Phase 1   EUCTR2022-002754-74-DE   Germany;Poland
   Actelion
      2008   Phase 3   NCT00660179   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Czech Republic;Denmark;Finland;Former Serbia and Montenegro;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Norway;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
      2018   Phase 3   EUCTR2017-003934-10-FR   Belgium;France;Poland
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2007-003694-27-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2011   -   EUCTR2007-003694-27-GB   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-IT   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-DE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-AT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2015   Phase 4   EUCTR2014-004066-20-NL   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-GB   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-DE   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2009   Phase 3   EUCTR2007-003694-27-DK   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-SK   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-PT   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-NL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-FR   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-FI   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Poland;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-003694-27-BE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-002440-14-SK   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Portugal;Slovakia;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Norway;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2008   -   EUCTR2007-002440-14-PT   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-NL   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-002440-14-GB   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Portugal;Slovakia;Sweden;United Kingdom
      2008   Phase 3   EUCTR2007-002440-14-FR   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Portugal;Slovakia;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-FI   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-DK   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-DE   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-BG   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Norway;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-002440-14-BE   Austria;Belgium;Bulgaria;Denmark;Finland;France;Germany;Italy;Netherlands;Portugal;Slovakia;Sweden;United Kingdom
      2008   -   EUCTR2007-002440-14-AT   Austria;Belgium;Bulgaria;Finland;France;Germany;Italy;Netherlands;Portugal;Sweden;United Kingdom
      -   Phase 3   EUCTR2007-003694-27-PL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Nippon Shinyaku co.,LTD./Actelion Pharmaceuticals Japan Ltd.
      2012   Phase 2-3   JPRN-jRCT2080221941   -
ACT-064992 / JNJ-67896062
   ACTELION Pharmaceuticals Ltd
      2017   Phase 3   EUCTR2016-001062-28-PT   Argentina;Australia;Austria;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Romania;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      2017   Phase 3   EUCTR2016-001062-28-AT   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2016-001062-28-PL   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
ACT-064992/ JNJ-67896062
   ACTELION Pharmaceuticals Ltd
      2019   Phase 3   EUCTR2016-001062-28-FI   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      2017   Phase 3   EUCTR2016-001062-28-PT   Argentina;Australia;Austria;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Romania;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
   Janssen Pharmaceutical K.K.
      -   Phase 3   EUCTR2023-000984-30-Outside-EU/EEA   Japan
ACT-064992D
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   Janssen Pharmaceutical K.K.
      2020   Phase 3   JPRN-jRCT2080224886   Europe;Japan;South America
ACT-178418
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
ACT-293987
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-002817-21-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 4   EUCTR2019-004783-22-NL   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-GB   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-FR   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-DE   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
   Actelion
      2010   Phase 3   NCT01112306   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2018   Phase 2   EUCTR2018-000145-39-HU   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-GB   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-FR   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-DE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 4   EUCTR2017-000216-42-PT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 4   EUCTR2017-000216-42-FR   Austria;France;Germany;Ireland;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-SE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-IE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-GB   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-DE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-AT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004035-21-DE   Germany;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2009-014992-31-GB   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   Phase 3   EUCTR2009-014992-31-SK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   Phase 3   EUCTR2009-014992-31-NL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   -   EUCTR2009-014490-41-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Slovakia;Spain;Sweden;United Kingdom
      2011   -   EUCTR2009-014490-41-NL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-SE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-PL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-IT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-IE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-HU   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Poland;Slovakia;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2009-014992-31-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Poland;Slovakia;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2009-014992-31-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Poland;Slovakia;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2009-014992-31-DK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-DE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-CZ   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-BE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-AT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-SE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-IT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-IE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-GR   Austria;Belgium;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Slovakia;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-014490-41-GB   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Slovakia;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-014490-41-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Hungary;Ireland;Italy;Netherlands;Slovakia;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-014490-41-DE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-CZ   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014490-41-BE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-AT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2009   -   EUCTR2009-014490-41-DK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2008   Phase 2   EUCTR2007-006453-12-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-006453-12-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-006453-12-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-HU   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      -   Phase 2   EUCTR2018-000145-39-PL   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      -   Phase 2   EUCTR2018-000145-39-BE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
   Actelion Pharmaceuticals Ltd.
      2021   Phase 3   EUCTR2019-002817-21-FI   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-PT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-LT   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-HU   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-ES   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-DE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-BE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2019   Phase 3   EUCTR2019-002817-21-PL   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2010   -   EUCTR2009-014490-41-HU   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2009   Phase 2   EUCTR2007-006453-12-AT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      -   Phase 3   EUCTR2019-002817-21-SE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2019-002817-21-IE   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-FR   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
ACT-385781A
   ACTELION Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-NL   Belgium;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-NL   Belgium;Canada;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-ES   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   Phase 3   EUCTR2010-018322-40-FR   Belgium;France;Italy;Netherlands;Spain
      2010   Phase 3   EUCTR2010-018322-40-BE   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   -   EUCTR2010-018320-10-BE   Belgium;Canada;France;Italy;Netherlands;Spain
   Actelion
      2010   Phase 4   NCT01105117   United States
      2010   Phase 4   NCT01105091   United States
   Actelion Pharmaceuticals Japan Ltd.
      2014   Phase 3   JPRN-jRCT2080222671   -
      2014   Phase 3   JPRN-jRCT2080222670   -
      2013   Phase 4   JPRN-jRCT1080222096   -
      2012   Phase 3   JPRN-jRCT1080221971   -
   Actelion Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-ES   Belgium;Canada;France;Italy;Netherlands;Spain
Actriia-IGG1FC
   ACCELERON PHARMA INC.
      2022   Phase 3   EUCTR2021-000199-12-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma Inc.
      2022   Phase 3   EUCTR2021-000199-12-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-FR   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-ES   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-FR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-ES   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-ES   Argentina;Australia;Austria;Belgium;Brazil;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 2   EUCTR2017-004738-27-BE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-GB   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-ES   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-DE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
   Acceleron Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2021-001498-21-DE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2020-005061-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-NL   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-BE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron, Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
Adcirca
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   ACTELION Pharmaceuticals France
      2015   Phase 4   EUCTR2015-002078-19-FR   France
   Actelion Pharmaceuticals Ltd
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
Adcirca 20 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas
   Bayer
      2021   -   NCT04813926   Puerto Rico;United States
      2017   Phase 4   NCT02891850   Australia;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   NCT02759419   France;Italy;Korea, Republic of;Poland;Thailand
      2015   Phase 3   NCT02562235   Belgium;Brazil;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2015   -   NCT02428985   Japan
      2014   Phase 4   NCT02191137   Puerto Rico;United States
      2014   Phase 3   NCT02007629   Belgium;Canada;Czech Republic;Czechia;France;Germany;Italy;Switzerland;United Kingdom;United States
      2010   Phase 2   NCT01179334   Austria;Czech Republic;Germany;Italy;New Zealand;Poland;Spain;United Kingdom;United States
      2008   Phase 3   NCT00810693   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-DE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-CZ   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 2;Phase 3   EUCTR2013-001759-10-BE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer Yakuhin, Ltd.
      2017   Phase 3   JPRN-jRCT2080223235   Asia except Japan;Europe;Japan;North America;South America
   Justus Liebig Universität Gießen
      2016   Phase 2   EUCTR2015-002835-17-DE   Germany
Adempas 0.5 MG
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Adempas 1 MG film coated tablet
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
Adempas 1.0 MG
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Adempas 1.5 MG
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Adempas 1.5 MG film coated tablet
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
Adempas 2 MG film coated tablet
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
Adempas 2.0 MG
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Adempas 2.5 MG
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Adempas 2.5 MG film coated tablet
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
Adempas filmtabletten
   Humanis Saglik Anonim Sirketi
      2023   Phase 1   NCT06180096   India
Adempas® 0.5 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas® 1.0 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas® 1.5 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas® 2.0 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas® 2.5 MG FILM-coated tablets
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas¿ 0.5 MG compressa rivestita CON film
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas¿ 1.0
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas¿ 1.5 MG
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas¿ 2.0 MG
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adempas¿ 2.5 MG
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Adipose derived mesenchymal stem cells
   Liaocheng People's Hospital
      2019   Phase 1/Phase 2   NCT04055415   China
AER-901 solution FOR nebulization
   Aerami Therapeutics
      2021   Phase 1   NCT04903730   Australia
Aerosolized iloprost
   Hannover Medical School
      2004   Phase 4   NCT00120380   Germany
AIR001
   Aires Pharmaceuticals, Inc.
      2013   Phase 2   NCT01725269   Australia;Hungary;United States
      2012   Phase 2   NCT01725256   Australia;Hungary;United States
AIR001 inhalation solution
   Aires Pharmaceuticals Inc
      2013   -   EUCTR2012-000166-37-PL   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000166-37-HU   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000166-37-DE   Australia;Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Poland;Romania;Serbia;United States
      2013   -   EUCTR2012-000166-37-CZ   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
   Aires Pharmaceuticals, Inc
      2013   -   EUCTR2012-000153-31-PL   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   Phase 2   EUCTR2012-000153-31-IT   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000153-31-HU   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000153-31-DE   Australia;Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Poland;Romania;Serbia;United States
      2013   -   EUCTR2012-000153-31-CZ   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
   Aires Pharmaceuticals, Inc.
      2008   Phase 1   NCT00814645   United States
Albuterol
   American Medical Association Foundation
      2014   Phase 2   NCT02108743   United States
   University of Miami
      2017   Phase 2   NCT03270332   United States
Allogeneic human cardiosphere-derived stem cells
   Cedars-Sinai Medical Center
      2017   Phase 1   NCT03145298   United States
Ambrisentan
   Brigham and Women's Hospital
      2008   Phase 4   NCT01338636   United States
   Gilead Sciences
      2008   Phase 4   NCT00617305   United States
      2005   Phase 2   NCT00423592   -
      2004   Phase 3   NCT00578786   Argentina;Brazil;Chile;Mexico
      2004   Phase 3   NCT00091598   Australia;Canada;United States
      2003   Phase 2   NCT00424021   -
      2003   Phase 3   NCT00423748   -
      2003   Phase 3   NCT00423202   -
   GlaxoSmithKline
      2012   Phase 3   NCT01808313   China
      2011   Phase 2   NCT01342952   Argentina;Brazil;Canada;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Russian Federation;Spain;United States
      2010   -   NCT01406327   -
      2010   Phase 3   NCT01178073   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline Research & Development Limited
      -   Phase 2   EUCTR2010-021572-29-FR   France;Germany;Greece;Hungary;Italy;Japan;Netherlands;Spain;United States
      -   -   EUCTR2010-019547-19-Outside-EU/EEA   Argentina;Brazil;Canada;Japan;Mexico;Russian Federation;United States
   GlaxoSmithKline Research & Development, Ltd
      2011   -   EUCTR2010-021572-29-NL   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-IT   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-HU   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   Phase 3   EUCTR2010-021572-29-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021572-29-GR   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-NL   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-IT   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-HU   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-GR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-FR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline, S.A
      2011   Phase 3   EUCTR2010-021572-29-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline, S.A.
      2010   Phase 2   EUCTR2010-019547-19-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline,S.A.
      2010   -   EUCTR2009-011150-17-ES   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
   Hamamatsu University School of Medicine
      2011   -   JPRN-UMIN000005464   Japan
   Heidelberg University
      2014   Phase 2   NCT02290613   Germany
   MYOGEN INC.
      2005   -   EUCTR2005-000812-29-IT   Belgium;Germany;Hungary;Italy;Spain
   Medical University of South Carolina
      2016   Phase 4   NCT02885012   United States
   Myogen Inc.
      2005   Phase 2   EUCTR2005-001564-31-DE   Belgium;Germany
      2005   -   EUCTR2005-001564-31-BE   Belgium;Germany
   Myogen, Inc
      2005   -   EUCTR2005-001193-28-AT   Austria
      2005   Phase 3   EUCTR2005-000812-29-ES   Austria;Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-DE   Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-BE   Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-AT   Austria;Belgium;Germany;Hungary;Italy;Spain
   Myogen, Inc.
      2005   Phase 3   EUCTR2005-000812-29-HU   Austria;Belgium;Germany;Hungary;Italy;Spain
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2061200058   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic Of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden
   Nanjing First Hospital, Nanjing Medical University
      2025   -   NCT06987097   -
      2022   -   NCT04972656   China
   National Jewish Health
      2012   -   NCT02169752   United States
   RenJi Hospital
      2020   Phase 1/Phase 2   NCT04528056   China
   Shanghai Pulmonary Hospital
      2015   -   ChiCTR-OON-17013521   China
   Thoraxklinik-Heidelberg gGmbH
      2014   Phase 2   EUCTR2014-001882-28-DE   Germany
   University of Alabama at Birmingham
      2011   Phase 4   NCT01330108   United States
Ambrisentan - high dose
   GlaxoSmithKline
      2011   Phase 2   NCT01332331   Argentina;Brazil;Canada;France;Germany;Greece;Hungary;Italy;Japan;Mexico;Netherlands;Russian Federation;Spain;United States
Ambrisentan - LOW dose
   GlaxoSmithKline
      2011   Phase 2   NCT01332331   Argentina;Brazil;Canada;France;Germany;Greece;Hungary;Italy;Japan;Mexico;Netherlands;Russian Federation;Spain;United States
Ambrisentan 5 MG FILM-coated tablets
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-SE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   Phase 4   EUCTR2009-011150-17-NL   Austria;Belgium;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-GR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   Phase 4   EUCTR2009-011150-17-GB   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-DE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-BE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-AT   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline Research & Development Limited
      2010   Phase 4   EUCTR2009-011150-17-FR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
Ambrisentan mimic
   Second Affiliated Hospital, School of Medicine, Zhejiang University
      2025   -   NCT06968962   -
Ambrisentan plus spironolactone
   Brigham and Women's Hospital
      2015   Phase 4   NCT02253394   United States
Ambrisentan tablet
   GlaxoSmithKline Research and Development Ltd
      2019   Phase 1   EUCTR2019-001699-12-GB   United Kingdom
AMN107
   NOVARTIS FARMA
      2010   -   EUCTR2010-019883-36-IT   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;United States
   Novartis Pharma AG
      2010   -   EUCTR2010-019883-36-HU   Germany;Hungary
   Novartis Pharma Services AG
      2011   -   EUCTR2010-019883-36-DE   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;Switzerland;United States
Anakinra
   Virginia Commonwealth University
      2016   Phase 1   NCT03057028   United States
Anastrozole
   University of Pennsylvania
      2017   Phase 2   NCT03229499   United States
      2012   Phase 2   NCT01545336   United States
Apabetalone
   Laval University
      2023   Phase 2   NCT04915300   Canada
   Steeve Provencher
      2019   Early Phase 1   NCT03655704   Canada
APD811
   Arena Pharmaceuticals, Inc.
      2023   Phase 3   EUCTR2018-001189-40-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2018-001187-33-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-RO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 2   EUCTR2014-000667-40-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2016   Phase 2   EUCTR2014-003042-27-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   -   EUCTR2014-000667-40-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-CZ   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
   UNITED THERAPEUTICS CORPORATION
      2020   Phase 3   EUCTR2019-003309-88-IT   Argentina;Australia;Austria;Belgium;Brazil;Czechia;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
   United Therapeutics
      2014   Phase 2   NCT02279160   Australia;Bulgaria;Czech Republic;Czechia;Hungary;Poland;Romania;Serbia;Spain;United States
   United Therapeutics Corporation
      2022   Phase 3   EUCTR2019-003309-88-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Singapore;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-PL   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-GB   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-ES   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-DE   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-SE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-RO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Türkiye;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-GB   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-SE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;Germany;Greece;Hungary;Israel;Korea, Republic of;Mexico;Netherlands;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-GB   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2018-001187-33-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2014-003042-27-CZ   Australia;Bulgaria;Czech Republic;Czechia;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
Apelin
   Golden Jubilee National Hospital
      2012   -   NCT01457170   United Kingdom
   Imperial College London
      2012   Phase 1   NCT01590108   United Kingdom
APL-9796
   Apollo Therapeutics Ltd
      2025   Phase 2   NCT06846554   United Kingdom
AR392830
   Arena Pharmaceuticals, Inc.
      2017   Phase 2   EUCTR2014-000667-40-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2016   Phase 2   EUCTR2014-003042-27-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   -   EUCTR2014-000667-40-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-CZ   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
   UNITED THERAPEUTICS CORPORATION
      2020   Phase 3   EUCTR2019-003309-88-IT   Argentina;Australia;Austria;Belgium;Brazil;Czechia;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
   United Therapeutics Corporation
      2022   Phase 3   EUCTR2019-003309-88-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Singapore;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-PL   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-GB   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-ES   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-DE   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-RO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Türkiye;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-SE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;Germany;Greece;Hungary;Israel;Korea, Republic of;Mexico;Netherlands;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2018-001187-33-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2014-003042-27-CZ   Australia;Bulgaria;Czech Republic;Czechia;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
Artesunate
   Joseph C. Wu
      2026   Phase 1   NCT06872112   United States
Aspirin
   Kawut, Steven, MD
      2002   Phase 2   NCT00105209   United States
   University of Pennsylvania
      2006   Phase 2   NCT00384865   United States
Assigned pulmonary hypertension medication
   Bayer
      2015   -   NCT02576002   United States
AV-101
   Aerovate Therapeutics
      2022   Phase 3   NCT05557942   Argentina;Australia;Belgium;Canada;Chile;China;Colombia;France;Germany;Israel;Italy;Latvia;Mexico;Poland;Portugal;Singapore;South Africa;Spain;United Kingdom;United States
      2021   Phase 2/Phase 3   NCT05036135   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Czechia;France;Germany;Greece;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
   Aerovate Therapeutics, Inc.
      2023   Phase 3   EUCTR2021-006864-25-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-LV   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-IE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-FR   Argentina;Australia;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-LV   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-IE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-FR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-ES   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czechia;France;Germany;Greece;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
Aviptadil
   MONDOGEN AG
      2008   -   EUCTR2007-003621-24-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
   MondoGEN AG
      2009   -   EUCTR2007-003621-24-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   Phase 2   EUCTR2007-003621-24-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   Phase 2   EUCTR2007-003621-24-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
AZD4831
   University of Cologne
      2020   Phase 2   EUCTR2020-002788-80-DE   Germany
Background PAH therapy
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
      2021   Phase 3   NCT04576988   Argentina;Australia;Belgium;Brazil;Canada;Czechia;France;Germany;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
   Merck Sharp & Dohme LLC
      2025   Phase 2   NCT06925750   Colombia;United Kingdom
      2024   Phase 2   NCT06664801   Argentina;Australia;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Singapore;Spain;Taiwan;Thailand;United Kingdom;United States
Bardoxolone methyl
   Reata Pharmaceuticals, Inc.
      2016   Phase 3   JPRN-UMIN000025158   Japan,North America,South America,Australia,Europe
      2016   Phase 3   EUCTR2016-000196-24-NL   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-GB   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-ES   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-DE   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-CZ   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-BE   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Spain;United Kingdom;United States
   Reata, a wholly owned subsidiary of Biogen
      2014   Phase 2   NCT02036970   Germany;Spain;United Kingdom;United States
Bardoxolone methyl capsules
   Reata, a wholly owned subsidiary of Biogen
      2016   Phase 3   NCT02657356   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Czechia;Germany;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
BAY 63-2521
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
   Bayer HealthCare AG
      2009   -   EUCTR2008-003610-94-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2009   -   EUCTR2008-003482-68-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
   Thoraxklinik Heidelberg gGmbH
      2022   Phase 2   EUCTR2021-001633-40-DE   Austria;France;Germany;Italy;Norway;Switzerland;United Kingdom
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
BAY 63-2521 coated tablets 0.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 1 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 1.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 2 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 2.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY 63-2521 IR tablets 0.5 MG
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
BAY 63-2521 IR tablets 1 MG
   Bayer HealthCare AG
      2011   -   EUCTR2011-001893-24-DE   Germany
BAY 63-2521 IR tablets 1.0 MG
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   Phase 2   EUCTR2010-018863-40-GB   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
BAY 63-2521 IR tablets 1.5 MG
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   Phase 2   EUCTR2010-018863-40-GB   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
BAY 63-2521 IR tablets 2.0 MG
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   Phase 2   EUCTR2010-018863-40-GB   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
BAY 63-2521 IR tablets 2.5 MG
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
BAY 63-2521 tablet
   Bayer AG
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-DE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-CZ   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
   Bayer HealthCare AG
      2014   Phase 3   EUCTR2013-001759-10-IT   Belgium;Canada;Czech Republic;Germany;Italy;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-FR   Belgium;Canada;Czech Republic;France;Germany;Italy;Switzerland;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2013-001759-10-BE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
BAY 63-2521 tablets 0.5 MG
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
BAY 63-2521 tablets 1 MG
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
BAY 63-2521 tablets 1.5 MG
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
BAY 63-2521 tablets 2 MG
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
BAY 63-2521 tablets 2.5 MG
   Bayer HealthCare AG
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
BAY Q 6256
   Bayer AG
      2013   Phase 1;Phase 2   EUCTR2013-002783-12-AT   Austria;Germany
   Bayer HealthCare AG
      2014   Phase 1;Phase 2   EUCTR2013-002783-12-DE   Austria;Germany
BAY1237592
   Bayer
      2019   Phase 1   NCT03754660   Austria;Czechia;Germany;Poland
BAY63-2521
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer
      2021   -   NCT04813926   Puerto Rico;United States
      2017   Phase 4   NCT02891850   Australia;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   NCT02759419   France;Italy;Korea, Republic of;Poland;Thailand
      2015   Phase 3   NCT02562235   Belgium;Brazil;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2015   -   NCT02428985   Japan
      2014   Phase 4   NCT02191137   Puerto Rico;United States
      2014   Phase 3   NCT02007629   Belgium;Canada;Czech Republic;Czechia;France;Germany;Italy;Switzerland;United Kingdom;United States
      2010   Phase 2   NCT01179334   Austria;Czech Republic;Germany;Italy;New Zealand;Poland;Spain;United Kingdom;United States
      2009   Phase 3   NCT00863681   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   NCT00810693   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
   Bayer Yakuhin, Ltd.
      2017   Phase 3   JPRN-jRCT2080223235   Asia except Japan;Europe;Japan;North America;South America
Beetroot juice
   Uppsala University
      2013   -   NCT02000856   Sweden
Benzbromaron AL
   Medical University of Graz
      2015   Phase 2   EUCTR2015-000709-38-AT   Austria
Benzbromarone
   Medical University of Graz
      2015   Phase 2   NCT02790450   Austria
      2015   Phase 2   EUCTR2015-000709-38-AT   Austria
Beraprost
   Hamamatsu University School of Medicine
      2017   -   JPRN-UMIN000025176   Japan
   Shanghai Pulmonary Hospital
      2009   -   ChiCTR-TCC-12002776   China
Beraprost sodium
   Dr. Soetomo General Hospital
      2017   Phase 4   NCT03431649   Indonesia
   Keio University
      2008   -   JPRN-UMIN000001350   Japan
Beraprost sodium 314D modified release tablets
   Lung Biotechnology Inc.
      2011   Phase 3   NCT01458236   -
   Lung Biotechnology PBC
      2013   Phase 3   NCT01908699   Israel;United States
Beraprost sodium modified release
   Lung Biotechnology PBC
      2010   Phase 2   NCT00989963   Belgium;Czech Republic;Czechia;Germany;Ireland;Romania;United States
      2009   Phase 2   NCT00990314   Belgium;Czech Republic;Czechia;Germany;Ireland;Romania;United States
      2009   Phase 2   NCT00792571   Belgium;Ireland;United States
      2009   Phase 2   NCT00781885   Belgium;Ireland;United States
   Lung LLC
      2010   -   EUCTR2009-014453-32-CZ   Belgium;Czech Republic;Germany;Ireland
      2010   Phase 2   EUCTR2009-014453-32-BE   Belgium;Czech Republic;Germany;Ireland;Romania;United States
      2009   -   EUCTR2008-006833-29-IE   Belgium;Ireland
      2009   Phase 2   EUCTR2008-006833-29-BE   Belgium;Ireland;United States
   Lung LLC Inc
      2010   -   EUCTR2009-014453-32-IE   Belgium;Czech Republic;Germany;Ireland
   Lung RX
      -   Phase 2   EUCTR2009-014453-32-DE   Belgium;Czech Republic;Germany;Ireland
   Lung Rx
      2010   -   EUCTR2009-014246-29-IE   Belgium;Czech Republic;Germany;Ireland
      2010   Phase 2   EUCTR2009-014246-29-DE   Belgium;Czech Republic;Germany;Ireland
      2009   -   EUCTR2008-003290-41-BE   Belgium;Ireland
   Lung Rx Inc
      2010   -   EUCTR2009-014246-29-CZ   Belgium;Czech Republic;Germany;Ireland
      2009   Phase 2   EUCTR2009-014246-29-BE   Belgium;Czech Republic;Germany;Ireland
   LungRx
      2009   -   EUCTR2008-003290-41-IE   Belgium;Ireland
BIA 5-1058
   BIAL-Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-IT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-IT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela & Ca, S.A
      2019   Phase 2   EUCTR2018-002796-18-GB   Austria;Belgium;Germany;Netherlands;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-GB   Austria;Germany;Netherlands;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-PT   Austria;Belgium;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002796-18-ES   Austria;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-DE   Austria;Belgium;France;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002796-18-AT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002448-10-PT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002448-10-ES   Austria;Portugal;Spain;Ukraine
      2018   Phase 2   EUCTR2018-002448-10-AT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela C S.A.
      2018   Phase 1   NCT04994860   Germany
      2018   Phase 1   NCT04994119   Germany
      2018   Phase 1   NCT04991207   Germany
      2018   Phase 1   NCT03708146   United Kingdom
      2018   Phase 1   NCT03489005   United Kingdom
      2015   Phase 1   NCT04991194   -
      2015   Phase 1   NCT04991155   -
BIA-5-1058
   BIAL-Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-IT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-PT   Austria;Belgium;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002796-18-ES   Austria;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002796-18-AT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
Biological dmards
   Hoffmann-La Roche
      2000   -   NCT02784808   -
Bisoprolol
   VU University Medical Center
      2011   Phase 1/Phase 2   NCT01246037   Netherlands
   VU medical center
      2011   -   EUCTR2010-020424-21-NL   Netherlands
Bosentan
   ACTELION PHARMACEUTICALS ITALIA
      2005   -   EUCTR2004-005157-63-IT   Italy;United Kingdom
      2005   -   EUCTR2004-000745-37-IT   Italy;Spain;United Kingdom
   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
      2013   Phase 2   NCT01827059   Netherlands
   Actelion
      2011   Phase 3   NCT01338415   Australia;Belarus;China;Czech Republic;Czechia;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   Phase 3   NCT01223352   Australia;Belarus;China;Czech Republic;Czechia;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2007   Phase 4   NCT00433329   United States
      2006   Phase 4   NCT00595049   Australia;United States
      2006   Phase 3   NCT00310830   France;Netherlands;United Kingdom;United States
      2006   Phase 4   NCT00303459   Brazil;Czech Republic;Denmark;Germany;Greece;Portugal;Saudi Arabia;Slovakia;Spain;Sweden;United Kingdom;United States
      2006   Phase 3   NCT00302211   United States
      2005   Phase 3   NCT00319267   France;Germany;Italy;Netherlands;Switzerland;United Kingdom;United States
      2005   Phase 3   NCT00319020   France;Germany;Italy;Netherlands;Switzerland;United Kingdom;United States
      2004   Phase 3   NCT00091715   Australia;Austria;Belgium;Canada;China;Czech Republic;France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;United States
      2003   Phase 4   NCT00317486   Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2003   Phase 4   NCT00082186   Australia;Brazil;Czech Republic;Hungary;United States
   Actelion Pharmaceuticals Japan Ltd.
      2013   Phase 3   JPRN-jRCT2080222109   -
      2013   Phase 3   JPRN-jRCT2080222108   -
      2012   Phase 3   JPRN-jRCT2080221952   -
   Actelion Pharmaceuticals Ltd
      2005   -   EUCTR2005-001967-70-IT   Germany;Italy;United Kingdom
      2004   -   EUCTR2004-000478-30-IT   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
   Actelion Pharmaceuticals Ltd.
      2011   -   EUCTR2010-021825-11-IT   Bulgaria;Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-IT   Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2008   -   EUCTR2005-005068-97-PT   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2005-005068-97-GR   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 4   EUCTR2005-005068-97-ES   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Slovakia;Spain;Sweden;United Kingdom
   Beijing Anzhen Hospital
      2011   -   ChiCTR-ONC-11001799   China
   Bial - Portela C S.A.
      2018   Phase 1   NCT04991207   Germany
   Fourth Military Medical University
      2012   Phase 3   NCT01712997   China
   Hamamatsu University School of Medicine
      2011   -   JPRN-UMIN000005464   Japan
   Hamilton Health Sciences Corporation
      2009   Phase 3   NCT00864201   Canada
   ICIN
      2010   -   EUCTR2008-004533-21-NL   Netherlands
   Medical University of Graz
      2008   -   NCT00909337   Austria
   NOVARTIS FARMA
      2011   -   EUCTR2010-021344-17-IT   Italy
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2061200058   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic Of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden
   Novartis Pharmaceuticals
      2011   Phase 3   NCT01392469   Australia;Belgium;Germany;Italy;Lithuania;Romania;Turkey;United Kingdom;United States
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2006   Phase 4   NCT00323297   Australia;Belgium;Czech Republic;Czechia;France;Germany;Greece;Israel;Italy;Taiwan;United Kingdom;United States
   Prof David S Celermajer
      2006   -   NCT01721564   -
   Rajan Saggar
      2007   Phase 4   NCT00625469   United States
   Royal Brompton and Harefield NHS Trust
      2008   Phase 4   EUCTR2007-001643-21-GB   United Kingdom
   Shanghai Pulmonary Hospital
      2015   -   ChiCTR-OON-17013521   China
   Stanford University
      2008   Phase 2   NCT00825266   United States
   Tokushima University
      2011   -   JPRN-UMIN000004369   Japan
   University of Cincinnati
      2008   Phase 2/Phase 3   NCT00581607   United States
   University of Edinburgh
      2009   Phase 0   NCT01100736   United Kingdom
   VU University Medical Center
      2013   Phase 4   NCT03236818   Netherlands
Bosentan administration
   Competence Network for Congenital Heart Defects
      2004   Phase 4   NCT00266162   Germany
Bosentan dispersible tablets
   Humanis Saglik Anonim Sirketi
      2024   Phase 1   NCT06484673   Jordan
Bosentan monohydrat
   Rigshospitalet
      2006   -   EUCTR2006-000021-57-DK   Denmark
Bosentan monohydrate
   Actelion Pharmaceuticals Ltd.
      2013   Phase 3   EUCTR2010-021825-11-BG   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021825-11-NL   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-NL   Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-HU   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-DE   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-CZ   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-HU   Bulgaria;Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021825-11-DE   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-CZ   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2009   -   EUCTR2005-005068-97-CZ   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2005-005068-97-BE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 4   EUCTR2005-005068-97-SK   Belgium;Brazil;Czech Republic;Denmark;Germany;Greece;Portugal;Saudi Arabia;Slovakia;Spain;Sweden;United Kingdom;United States
      2007   -   EUCTR2005-005068-97-SE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-GB   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-DK   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2006   -   EUCTR2004-004391-36-CZ   Czech Republic;Hungary
      2006   -   EUCTR2004-000745-37-GB   Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001967-70-GB   Germany;Italy;United Kingdom
      2005   Phase 3   EUCTR2004-005157-63-GB   Italy;United Kingdom
      2005   -   EUCTR2004-004391-36-HU   Czech Republic;Hungary
      2005   Phase 3   EUCTR2004-000478-30-ES   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 4   EUCTR2004-000745-37-ES   Italy;Spain;United Kingdom
      2004   -   EUCTR2004-000478-30-SE   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 3   EUCTR2004-000478-30-GB   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-DK   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-CZ   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-BE   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-AT   Austria;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2010-021825-11-FR   Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Spain
      -   Phase 3   EUCTR2010-021793-12-PL   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      -   Phase 3   EUCTR2010-021793-12-FR   Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      -   -   EUCTR2005-001967-70-DE   Germany;Italy;United Kingdom
   Actelion pharmaceuticals Ltd
      2012   -   EUCTR2011-004612-31-PT   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      2012   -   EUCTR2011-004106-16-PT   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      2012   Phase 3   EUCTR2011-004106-16-BG   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004612-31-NL   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004612-31-FR   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004106-16-NL   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;South Africa;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004106-16-FR   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
Bosentan, ambrisentan
   West Penn Allegheny Health System
      2005   -   NCT00593905   United States
BPS-314D-MR
   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
      2013   Phase 2   NCT01966302   United States
BPS-MR
   Lung LLC
      2010   -   EUCTR2009-014453-32-CZ   Belgium;Czech Republic;Germany;Ireland
      2010   Phase 2   EUCTR2009-014453-32-BE   Belgium;Czech Republic;Germany;Ireland;Romania;United States
      2009   -   EUCTR2008-006833-29-IE   Belgium;Ireland
      2009   Phase 2   EUCTR2008-006833-29-BE   Belgium;Ireland;United States
   Lung LLC Inc
      2010   -   EUCTR2009-014453-32-IE   Belgium;Czech Republic;Germany;Ireland
   Lung RX
      -   Phase 2   EUCTR2009-014453-32-DE   Belgium;Czech Republic;Germany;Ireland
   Lung Rx
      2010   -   EUCTR2009-014246-29-IE   Belgium;Czech Republic;Germany;Ireland
      2010   Phase 2   EUCTR2009-014246-29-DE   Belgium;Czech Republic;Germany;Ireland
      2009   -   EUCTR2008-003290-41-BE   Belgium;Ireland
   Lung Rx Inc
      2010   -   EUCTR2009-014246-29-CZ   Belgium;Czech Republic;Germany;Ireland
      2009   Phase 2   EUCTR2009-014246-29-BE   Belgium;Czech Republic;Germany;Ireland
   LungRx
      2009   -   EUCTR2008-003290-41-IE   Belgium;Ireland
Breelib nebulizer
   Bayer
      2018   -   NCT03293407   Germany
Bromure D'ipratropium
   ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
      2016   Phase 3   EUCTR2014-002590-10-FR   France
BSF 208075
   Gilead Sciences
      2002   Phase 2   NCT00046319   Australia;Belgium;France;Germany;Italy;United States
   MYOGEN INC.
      2005   -   EUCTR2005-000812-29-IT   Belgium;Germany;Hungary;Italy;Spain
   Myogen Inc.
      2005   Phase 2   EUCTR2005-001564-31-DE   Belgium;Germany
   Myogen, Inc
      2005   -   EUCTR2005-001193-28-AT   Austria
      2005   Phase 3   EUCTR2005-000812-29-ES   Austria;Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-DE   Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-BE   Belgium;Germany;Hungary;Italy;Spain
      2005   -   EUCTR2005-000812-29-AT   Austria;Belgium;Germany;Hungary;Italy;Spain
   Myogen, Inc.
      2005   Phase 3   EUCTR2005-000812-29-HU   Austria;Belgium;Germany;Hungary;Italy;Spain
BSF 208075 or LU 208075
   Myogen Inc.
      2005   -   EUCTR2005-001564-31-BE   Belgium;Germany
C07ab07
   VU medical center
      2011   -   EUCTR2010-020424-21-NL   Netherlands
C225
   VU University Medical Centre
      2006   -   EUCTR2006-002081-19-NL   Netherlands
Calcifediol oral capsule
   Parc de Salut Mar
      2024   Phase 4   NCT06258850   -
Capsaicin
   Imperial College London
      2011   -   EUCTR2011-001312-59-GB   United Kingdom
   University of Rochester
      2010   Phase 2   NCT01260454   United States
Captopril
   Hebei Medical University
      2005   Phase 1   NCT00240656   China
Carbon monoxide
   University of Illinois at Chicago
      2012   Phase 1/Phase 2   NCT01523548   United States
Cardiomems pulmonary artery pressure monitor
   Sheffield Teaching Hospitals NHS Foundation Trust
      2023   Phase 4   NCT05825417   United Kingdom
Carvedilol
   Hebei Medical University
      2005   Phase 1   NCT00240656   China
   The Cleveland Clinic
      2012   -   NCT01586156   United States
   The Hospital for Sick Children
      2012   Phase 1/Phase 2   NCT01723371   Canada
   University of Minnesota
      2016   Phase 2   NCT02507011   United States
      2014   Phase 1   NCT02120339   United States
   Virginia Commonwealth University
      2010   Phase 1/Phase 2   NCT00964678   United States
Cetuximab
   VU University Medical Centre
      2006   -   EUCTR2006-002081-19-NL   Netherlands
Chlorhexidine
   Department of cardiology, Keio University School of Medicine
      2011   -   JPRN-UMIN000005438   Japan
Cialis
   Eli Lilly and Company
      2006   -   EUCTR2005-002844-24-DE   Germany;Ireland;Italy;Spain;United Kingdom
   Eli Lilly and Company Limited
      2006   Phase 3;Phase 4   EUCTR2005-002844-24-BE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-SE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   Phase 4   EUCTR2009-011150-17-NL   Austria;Belgium;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-IT   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-GR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   Phase 4   EUCTR2009-011150-17-GB   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-DE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-BE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-AT   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline Research & Development Limited
      2010   Phase 4   EUCTR2009-011150-17-FR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
   Lilly ICOS LLC
      2006   -   EUCTR2005-002844-24-IE   Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002844-24-GB   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002844-24-ES   Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-IE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-GB   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-ES   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002692-33-DE   Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002692-33-BE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
Cialis 10 MG FILM-coated tablets
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Cialis 2.5 MG FILM-coated tablets
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Cialis 20 MG comprimidos recubiertos CON PELícula
   GlaxoSmithKline,S.A.
      2010   -   EUCTR2009-011150-17-ES   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
Cialis 20 MG FILM-coated tablets
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Cialis 5 MG FILM-coated tablets
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Cicletanine
   Gilead Sciences
      2009   Phase 2   NCT00832507   Australia;Austria;Belgium;Canada;Germany;Israel;Mexico;Spain;United Kingdom;United States
Cicletanine hydrochloride
   Gilead Sciences, Inc.
      2010   -   EUCTR2008-007455-26-AT   Austria;Belgium;Germany;Spain;United Kingdom
      2009   Phase 2   EUCTR2008-007455-26-GB   Austria;Belgium;Germany;Spain;United Kingdom
      2009   -   EUCTR2008-007455-26-ES   Austria;Belgium;Germany;Spain;United Kingdom
      2009   -   EUCTR2008-007455-26-DE   Australia;Austria;Belgium;Canada;Germany;Israel;Mexico;Spain;United Kingdom;United States
      2009   Phase 2   EUCTR2008-007455-26-BE   Austria;Belgium;Germany;Spain;United Kingdom
Clopidogrel
   Kawut, Steven, MD
      2002   Phase 2   NCT00105209   United States
Cmri
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
Coenzyme Q-10 IN normal control subjects
   The Cleveland Clinic
      2010   -   NCT01148836   United States
Coenzyme Q-10 IN pulmonary hypertension subjects
   The Cleveland Clinic
      2010   -   NCT01148836   United States
Confirm RX
   Sheffield Teaching Hospitals NHS Foundation Trust
      2023   Phase 4   NCT05825417   United Kingdom
Crono five ambulatory pump
   United Therapeutics
      2007   Phase 4   NCT00439946   United States
CS1
   Cereno Scientific AB
      2019   -   NCT06321705   Sweden
CS1 administration
   Cereno Scientific AB
      2022   Phase 2   NCT05224531   Sweden
CXA-10
   Complexa Inc.
      2019   Phase 2   EUCTR2019-002414-40-GB   United Kingdom;United States
   Complexa, Inc.
      2019   Phase 2   NCT04053543   United Kingdom;United States
   Gladwin, Mark, MD
      2019   Phase 2   NCT04125745   United States
D-glucose
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
D.3.6.2 - dose massima specificare: giornaliera
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
Dapagliflozin
   Mads Ersbøll
      2023   Phase 2   NCT05179356   Denmark
   Rigshospitalet The Heart Center
      2022   Phase 2   EUCTR2021-006787-25-DK   Denmark
Dhea tablet
   Rhode Island Hospital
      2019   Phase 2   NCT03648385   United States
Dichloroacetate sodium
   University of Alberta
      2010   Phase 1   NCT01083524   Canada;United Kingdom
Dietanolamina DE treprostinilo
   United Therapeutics Corporation
      2007   -   EUCTR2006-000804-18-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
Diltiazem hydrochloride
   University of South Florida
      2012   -   NCT01645826   United States
Dimethyl fumarate
   Robert Lafyatis
      2016   Phase 1   NCT02981082   United States
Diphenhydramine
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
Dobutamine test
   Shanghai Zhongshan Hospital
      2022   -   NCT05587400   China
Dose A KER-012
   Keros Therapeutics, Inc.
      2023   Phase 2   NCT05975905   Australia;Brazil;France;Germany;Korea, Republic of;Poland;Portugal;Spain;Taiwan;United Kingdom;United States
Dose B KER-012
   Keros Therapeutics, Inc.
      2023   Phase 2   NCT05975905   Australia;Brazil;France;Germany;Korea, Republic of;Poland;Portugal;Spain;Taiwan;United Kingdom;United States
Dose C KER-012
   Keros Therapeutics, Inc.
      2023   Phase 2   NCT05975905   Australia;Brazil;France;Germany;Korea, Republic of;Poland;Portugal;Spain;Taiwan;United Kingdom;United States
DUO-therapy with sildenafil + bosentan
   Johns Hopkins University
      2022   Phase 3   NCT04039464   Canada;United States
E-learning
   Amsterdam UMC, location VUmc
      2019   -   NCT05318950   Netherlands
EFI/ACT-385781A
   Actelion
      2011   Phase 3   NCT01431716   Belgium;Canada;France;Italy;Netherlands;Spain
Elafin
   Roham T. Zamanian
      2019   Phase 1   NCT03522935   United States
Emea/H/C/002677
   Amsterdam UMC, location VUmc
      2023   Phase 2   EUCTR2022-002400-20-NL   Netherlands
Empagliflozin
   Amsterdam UMC, location VUmc
      2023   Phase 2   EUCTR2022-002400-20-NL   Netherlands
Empagliflozin 10 MG
   Amsterdam UMC, location VUmc
      2023   Phase 2   NCT05493371   Netherlands
Empagliflozin IN treatment pulmonary aerterial hypertension
   China National Center for Cardiovascular Diseases
      2024   Phase 1   NCT06554301   China
Endogenous thrombin potential
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
Endothelin receptor antagonist therapy
   Actelion
      2015   -   NCT02309463   -
Endothelin receptor antagonists
   Brigham and Women's Hospital
      2021   -   NCT05039086   United States
Endothelin-3
   University of Edinburgh
      2009   Phase 0   NCT01100736   United Kingdom
Enos transfected epcs will BE delivered VIA A PA line
   Northern Therapeutics
      2006   Phase 1   NCT00469027   Canada
Epicatechin
   University of California, San Francisco
      2013   Phase 1   NCT01880866   United States
Epoprostenol
   Actelion
      2011   Phase 3   NCT01470144   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   Phase 4   NCT01105117   United States
      2010   Phase 4   NCT01105091   United States
   Actelion Pharmaceuticals Japan Ltd.
      2014   Phase 3   JPRN-jRCT2080222671   -
      2014   Phase 3   JPRN-jRCT2080222670   -
      2012   Phase 3   JPRN-jRCT1080221971   -
   GlaxoSmithKline Research and Development Limited
      2011   -   EUCTR2011-002943-92-NL   Canada;Netherlands;United States
Epoprostenol FOR injection
   ACTELION Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-NL   Belgium;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-NL   Belgium;Canada;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-ES   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   Phase 3   EUCTR2010-018322-40-BE   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   -   EUCTR2010-018320-10-BE   Belgium;Canada;France;Italy;Netherlands;Spain
   Actelion Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-ES   Belgium;Canada;France;Italy;Netherlands;Spain
   Actelion Pharmaceuticals Ltd.
      2011   -   EUCTR2010-018322-40-IT   Belgium;Canada;France;Italy;Netherlands;Spain
Epoprostenol sodico
   Actelion Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-ES   Belgium;Canada;France;Italy;Netherlands;Spain
Epoprostenol sodium
   ACTELION Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-NL   Belgium;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-NL   Belgium;Canada;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-ES   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   Phase 3   EUCTR2010-018322-40-FR   Belgium;France;Italy;Netherlands;Spain
      2010   Phase 3   EUCTR2010-018322-40-BE   Belgium;Canada;France;Italy;Netherlands;Spain
      2010   -   EUCTR2010-018320-10-BE   Belgium;Canada;France;Italy;Netherlands;Spain
   Actelion Pharmaceuticals Japan Ltd.
      2013   Phase 4   JPRN-jRCT1080222096   -
   Actelion Pharmaceuticals Ltd
      2011   -   EUCTR2010-018322-40-ES   Belgium;Canada;France;Italy;Netherlands;Spain
   Actelion Pharmaceuticals Ltd.
      2011   -   EUCTR2010-018320-10-IT   Belgium;Canada;Italy;Netherlands;Spain
Epoprostenol-actelion
   ACTELION Pharmaceuticals Ltd
      2010   Phase 3   EUCTR2010-018322-40-FR   Belgium;France;Italy;Netherlands;Spain
Epoprostenolo PER iniezione
   Actelion Pharmaceuticals Ltd.
      2011   -   EUCTR2010-018322-40-IT   Belgium;Canada;France;Italy;Netherlands;Spain
      2011   -   EUCTR2010-018320-10-IT   Belgium;Canada;Italy;Netherlands;Spain
ERA AS specific PAH treatment
   Eli Lilly and Company
      2014   Phase 3   NCT01824290   Austria;Belgium;Brazil;Canada;France;Germany;Israel;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;Turkey;United States
Erbitux
   VU University Medical Centre
      2006   -   EUCTR2006-002081-19-NL   Netherlands
Esomeprazole
   United Therapeutics
      2009   Phase 1   NCT00963027   United States
ESR-specific PET scan
   Vanderbilt University Medical Center
      2021   -   NCT04280523   United States
Esuberaprost
   Lung Biotechnology PBC
      2018   Phase 3   NCT03657095   Israel;United States
Eutonic treprostinil solution
   Jewish General Hospital
      2012   Phase 4   NCT01615627   Canada
Famotidine 20 MG
   University of Washington
      2019   Phase 2   NCT03554291   United States
FDC macitentan/tadalafil
   Actelion
      2019   Phase 3   NCT03904693   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   Janssen Pharmaceutical K.K.
      2020   Phase 3   JPRN-jRCT2080224886   Europe;Japan;South America
Ferinject
   Imperial College Academic Healthsciences Centre
      2016   Phase 2   EUCTR2010-024585-22-DE   Germany;United Kingdom
      2011   Phase 2   EUCTR2010-024585-22-GB   Germany;United Kingdom
   VU university medical center
      2010   -   EUCTR2010-023233-30-NL   Netherlands
Ferinject or cosmofer
   Imperial College London
      2011   Phase 2   NCT01447628   China;Germany;United Kingdom
Ferric carboxymaltose
   Imperial College Academic Healthsciences Centre
      2016   Phase 2   EUCTR2010-024585-22-DE   Germany;United Kingdom
      2011   Phase 2   EUCTR2010-024585-22-GB   Germany;United Kingdom
   VU university medical center
      2010   -   EUCTR2010-023233-30-NL   Netherlands
Ferricarboxymaltose
   VU University Medical Center
      2011   Phase 4   NCT01288651   Netherlands
FK506 level 2-3 NG/ML
   Edda Spiekerkoetter
      2012   Phase 2   NCT01647945   United States
FK506 level 3-5 NG/ML
   Edda Spiekerkoetter
      2012   Phase 2   NCT01647945   United States
FK506 level < 2 NG/ML
   Edda Spiekerkoetter
      2012   Phase 2   NCT01647945   United States
Flolan injection with currently marketed diluent
   GlaxoSmithKline
      2016   Phase 4   NCT02705807   Japan
Flolan injection with reformulated diluent
   GlaxoSmithKline
      2016   Phase 4   NCT02705807   Japan
Flolan TM and glycine diluent
   GlaxoSmithKline Research and Development Limited
      2011   -   EUCTR2011-002943-92-NL   Canada;Netherlands;United States
Flolan™ and glycine diluent
   GlaxoSmithKline Research and Development Limited
      2011   -   EUCTR2011-002943-92-NL   Canada;Netherlands;United States
Fluoxetine
   University of Texas Southwestern Medical Center
      2013   Phase 2   NCT03638908   United States
      2009   Phase 2   NCT00942708   United States
Forxiga
   Rigshospitalet The Heart Center
      2022   Phase 2   EUCTR2021-006787-25-DK   Denmark
Fulvestrant
   University of Pennsylvania
      2017   Phase 2   NCT02911844   United States
Furosemide
   Chinese Pulmonary Vascular Disease Research Group
      2021   -   NCT05569655   China
G04be03
   PFIZER
      2006   -   EUCTR2006-001464-23-IT   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
G04be08
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
Gadolinium
   Ottawa Heart Institute Research Corporation
      2018   Phase 4   NCT03344159   Canada
GB002
   GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
      2021   Phase 2   NCT04816604   Australia;Belgium;Czechia;France;Germany;Spain;United Kingdom;United States
      2020   Phase 2   NCT04456998   Australia;Austria;Belgium;Canada;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2020   Phase 1   NCT03926793   United Kingdom;United States
GB002 capsules
   GB002, Inc.
      2022   Phase 2   EUCTR2020-005169-15-BE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-ES   Australia;Austria;Belgium;Canada;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-AT   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-DE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-BE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-GB   Australia;Austria;Belgium;Canada;France;Germany;Israel;Serbia;Singapore;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-FR   Australia;Austria;Belgium;Canada;France;Germany;Israel;Serbia;Singapore;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-AT   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2019   Phase 1;Phase 2   EUCTR2018-003093-27-GB   Denmark;France;Netherlands;Sweden;United Kingdom;United States
Generic DRY powder inhaler
   GB002, Inc.
      2023   Phase 3   NCT05934526   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Romania;Saudi Arabia;Serbia;Singapore;Spain;United Kingdom;United States
   GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
      2021   Phase 2   NCT04816604   Australia;Belgium;Czechia;France;Germany;Spain;United Kingdom;United States
      2020   Phase 2   NCT04456998   Australia;Austria;Belgium;Canada;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2020   Phase 1   NCT03926793   United Kingdom;United States
Gereic DRY powder inhaler
   GB002, Inc.
      2024   Phase 3   NCT06274801   Argentina;Australia;Belgium;Chile;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Spain;United Kingdom;United States
Glivec
   NOVARTIS FARMA
      2011   -   EUCTR2010-021960-14-IT   Germany;Italy
      2011   -   EUCTR2010-021344-17-IT   Italy
      2010   -   EUCTR2009-018167-26-IT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2009   -   EUCTR2009-012057-38-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharma AG
      2011   -   EUCTR2010-021960-14-DE   Germany;Italy
      2010   Phase 3   EUCTR2009-018167-26-GB   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-FR   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-DE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   Phase 3   EUCTR2009-018167-26-BE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-012057-38-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharma Services AG
      2010   -   EUCTR2009-018167-26-AT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2009   -   EUCTR2009-012057-38-SE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2006   -   EUCTR2005-005569-12-GB   Austria;Germany;United Kingdom
      2006   -   EUCTR2005-005569-12-AT   Austria;Germany;United Kingdom
Glivec 100 MG comprimidos recubiertos CON PELícula
   Novartis Farmacéutica SA
      2009   -   EUCTR2009-012057-38-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Farmacéutica, S.A.
      2013   -   EUCTR2013-001100-10-ES   Australia;Spain;Switzerland;United States
Glivec 100 MG filmtabletten
   Novartis Pharma Services AG
      2006   -   EUCTR2005-005569-12-DE   Austria;Germany;United Kingdom
Glivec 100 MG hartkapsel
   Novartis Pharma Services AG
      2006   -   EUCTR2005-005569-12-DE   Austria;Germany;United Kingdom
Glivec® 100 MG filmtabletten
   Novartis Pharma Services AG
      2009   -   EUCTR2009-012057-38-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
GMA301 injection
   Gmax Biopharm Australia Pty Ltd.
      2020   Phase 1   NCT04505137   Australia
GS-4997 18 MG
   Gilead Sciences, Inc.
      2015   Phase 2   EUCTR2014-002131-34-NL   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-IT   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-GB   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-ES   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-DE   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
GS-4997 2 MG
   Gilead Sciences, Inc.
      2015   Phase 2   EUCTR2014-002131-34-NL   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-IT   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-GB   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-ES   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-DE   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
GS-4997 6 MG
   Gilead Sciences, Inc.
      2015   Phase 2   EUCTR2014-002131-34-NL   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-IT   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-GB   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-ES   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002131-34-DE   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
GSK1325760
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-SE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   Phase 4   EUCTR2009-011150-17-NL   Austria;Belgium;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-IT   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-GR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   Phase 4   EUCTR2009-011150-17-GB   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-DE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-BE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-AT   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline Research & Development Limited
      2010   Phase 4   EUCTR2009-011150-17-FR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      -   Phase 2   EUCTR2010-021572-29-FR   France;Germany;Greece;Hungary;Italy;Japan;Netherlands;Spain;United States
      -   -   EUCTR2010-019547-19-Outside-EU/EEA   Argentina;Brazil;Canada;Japan;Mexico;Russian Federation;United States
   GlaxoSmithKline Research & Development, Ltd
      2011   -   EUCTR2010-021572-29-NL   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-IT   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-HU   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   Phase 3   EUCTR2010-021572-29-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021572-29-GR   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-NL   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-IT   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-HU   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-GR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-FR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline Research and Development Ltd
      2019   Phase 1   EUCTR2019-001699-12-GB   United Kingdom
   GlaxoSmithKline, S.A
      2011   Phase 3   EUCTR2010-021572-29-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline, S.A.
      2010   Phase 2   EUCTR2010-019547-19-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
GSK1325760A
   GlaxoSmithKline
      2008   Phase 3   NCT00554619   Japan
      2007   Phase 2   NCT00540436   Japan
GSK2256098
   GlaxoSmithKline
      2015   Phase 1   NCT02551653   United Kingdom
GSK2586881
   GlaxoSmithKline
      2018   Phase 2   NCT03177603   Germany;Spain;United States
   GlaxoSmithKline Research & Development Ltd
      2017   Phase 2   EUCTR2017-000212-41-DE   Germany;Spain;United States
   GlaxoSmithKline, S.A.
      2017   Phase 2   EUCTR2017-000212-41-ES   Germany;Spain;United States
HGP1206
   Hanmi Pharmaceutical Company Limited
      2013   Phase 1   NCT01864863   Korea, Republic of
HS135
   35Pharma Inc
      2024   Phase 1   NCT06493461   Canada;Germany
Hydroxyurea
   National Heart, Lung, and Blood Institute (NHLBI)
      2013   Early Phase 1   NCT01950585   United States
Hyperpolarized 129XE
   Bastiaan Driehuys
      2023   Phase 2   NCT04778046   United States
Hyperpolarized 13C-pyruvate
   University of Texas Southwestern Medical Center
      2022   -   NCT04968210   United States
Hyperpolarized XE129
   University of Kansas Medical Center
      2022   -   NCT05339386   United States
Hypotonictreprostinil solution
   Jewish General Hospital
      2012   Phase 4   NCT01615627   Canada
I-NEB AAD system
   Bayer
      2016   -   NCT02826252   Germany
I.V. selexipag
   Actelion
      2017   Phase 3   NCT03187678   Germany;United States
IKT-001PRO
   Inhibikase Therapeutics, Inc.
      2025   Phase 2   NCT06643143   -
IL-6
   Zhongda Hospital Affiliated to Southeast University
      2020   -   ChiCTR1900028152   China
Ilomedin 20
   Bayer AG
      2013   Phase 1;Phase 2   EUCTR2013-002783-12-AT   Austria;Germany
   Bayer HealthCare AG
      2014   Phase 1;Phase 2   EUCTR2013-002783-12-DE   Austria;Germany
Iloprost
   Actelion
      2009   -   NCT00902603   United States
      2008   Phase 3   NCT00709956   Austria;Germany;United States
      2008   Phase 3   NCT00709098   Austria;Germany;United States
      2006   Phase 2   NCT00453414   United States
      2006   Phase 3   NCT00302211   United States
      2004   Phase 2   NCT00086463   United States
   Actelion Pharmaceuticals Ltd
      2009   -   EUCTR2009-010703-80-DE   Austria;Germany
      2009   -   EUCTR2009-010703-80-AT   Austria;Germany
   Actelion Pharmaceuticals Ltd.
      2009   -   EUCTR2009-011013-24-AT   Austria
   Actelion Pharmaceuticals US, Inc.
      2006   -   EUCTR2005-006192-13-GB   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   -   EUCTR2005-006192-13-DE   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   -   EUCTR2005-006192-13-AT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   Bayer
      2018   -   NCT03293407   Germany
      2016   -   NCT02826252   Germany
      2016   -   NCT02825160   Japan
      2013   -   NCT01894035   Portugal
      2013   -   NCT01781052   France
      2012   Phase 3   NCT01469169   Japan
      2011   -   NCT01468545   Spain
      2010   -   NCT01355380   Poland
      2006   -   NCT01062282   Korea, Republic of
   Bayer AG
      2013   Phase 1;Phase 2   EUCTR2013-002783-12-AT   Austria;Germany
   Bayer HealthCare AG
      2014   Phase 1;Phase 2   EUCTR2013-002783-12-DE   Austria;Germany
   COTHERIX, INC.
      2006   Phase 3   EUCTR2005-006192-13-IT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   CoTherix, Inc
      2007   -   EUCTR2005-006192-13-PT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-006192-13-ES   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   Fourth Military Medical University
      2012   Phase 3   NCT01712997   China
   Gachon University Gil Medical Center
      2010   -   NCT01054105   Korea, Republic of
   Royal Brompton and Harefield NHS Foundation Trust
      2014   Phase 4   EUCTR2014-000091-25-GB   United Kingdom
   The University of Tokushima Graduate School of Health Biosciences
      2017   -   JPRN-UMIN000027284   Japan
   Univ.Clinic of Internal Medicine II, Department of Cardiology, Medical University of Vienna, Austria
      2008   -   EUCTR2007-002803-42-AT   Austria
   University of California, Los Angeles
      2011   -   NCT01319045   United States
   University of Cincinnati
      2006   Phase 4   NCT00403650   United States
   University of Giessen
      2017   -   NCT03365479   Germany
Iloprost PD-15
   Actelion
      2008   Phase 3   NCT00723554   United States
Iloprost PD-6
   Actelion
      2008   Phase 3   NCT00723554   United States
Imatinib
   Aerovate Therapeutics, Inc.
      2023   Phase 3   EUCTR2021-006864-25-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-LV   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-IE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-FR   Argentina;Australia;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2023   Phase 3   EUCTR2021-006864-25-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-LV   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2023   Phase 2;Phase 3   EUCTR2021-001910-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-IE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Latvia;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Singapore;South Africa;Spain;Sweden;Türkiye;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-FR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-ES   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czechia;France;Germany;Greece;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
   Medical Education Center
      2008   -   JPRN-UMIN000001578   Japan
   NOVARTIS FARMA
      2010   -   EUCTR2009-018167-26-IT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2009   -   EUCTR2009-012057-38-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Farmacéutica SA
      2009   -   EUCTR2009-012057-38-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharma K.K.
      2014   Phase 3   JPRN-jRCT2080222412   -
   Novartis Pharma Services AG
      2006   -   EUCTR2005-005569-12-GB   Austria;Germany;United Kingdom
      2006   -   EUCTR2005-005569-12-DE   Austria;Germany;United Kingdom
      2006   -   EUCTR2005-005569-12-AT   Austria;Germany;United Kingdom
   Novartis Pharmaceuticals
      2011   Phase 3   NCT01392495   Australia;Belgium;Germany;Italy;Lithuania;Turkey;United Kingdom;United States
      2011   Phase 3   NCT01392469   Australia;Belgium;Germany;Italy;Lithuania;Romania;Turkey;United Kingdom;United States
      2010   Phase 3   NCT01117987   Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
Imatinib mesilate
   Imperial College London
      2020   Phase 2   EUCTR2020-001157-48-GB   United Kingdom
   Novartis Farmacéutica, S.A.
      2013   -   EUCTR2013-001100-10-ES   Australia;Spain;Switzerland;United States
   Novartis Pharma AG
      2011   -   EUCTR2010-021960-14-DE   Germany;Italy
   Novartis Pharma Services AG
      2009   -   EUCTR2009-012057-38-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
Imatinib mesylate
   Imperial College London
      2021   Phase 2   NCT04416750   United Kingdom
   NOVARTIS FARMA
      2011   -   EUCTR2010-021960-14-IT   Germany;Italy
      2011   -   EUCTR2010-021344-17-IT   Italy
   Novartis Pharma AG
      2010   Phase 3   EUCTR2009-018167-26-GB   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-FR   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-DE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   Phase 3   EUCTR2009-018167-26-BE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-012057-38-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharma Services AG
      2010   -   EUCTR2009-018167-26-AT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2009   -   EUCTR2009-012057-38-SE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharmaceuticals
      2009   Phase 3   NCT00902174   Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2006   Phase 2/Phase 3   NCT00477269   Austria;Germany;United Kingdom;United States
Inhaled nitric oxide
   Bellerophon Pulse Technologies
      2016   Phase 3   NCT02652429   Canada;United States
   Geno LLC
      2015   Phase 3   NCT02436512   United States
      2011   Phase 2   NCT01265888   United States
   Shanghai Zhongshan Hospital
      2022   -   NCT05587400   China
Inhaled nitric oxide & inopulse delivery
   BELLEROPHON PULSE TECHNOLOGIES LLC
      2016   Phase 3   EUCTR2015-005223-90-IT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
   Bellerophon Pulse Technologies LLC
      2018   Phase 3   EUCTR2015-005223-90-BE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-NL   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-HR   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-AT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-PT   Australia;Austria;Belgium;Canada;Croatia;Czech Republic;France;Germany;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-GB   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-DE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-CZ   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
Inhaled nitric oxide 75 MCG/KG IBW/HR
   Bellerophon Pulse Technologies
      2016   Phase 3   NCT02725372   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czechia;France;Germany;Israel;Italy;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
Inhaled NO with pulsed delivery
   BELLEROPHON PULSE TECHNOLOGIES LLC
      2016   Phase 3   EUCTR2015-005223-90-IT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
   Bellerophon Pulse Technologies LLC
      2018   Phase 3   EUCTR2015-005223-90-BE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-NL   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-HR   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-AT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-PT   Australia;Austria;Belgium;Canada;Croatia;Czech Republic;France;Germany;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-GB   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-DE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-CZ   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
Inhaled prostacyclin
   United Therapeutics
      2010   -   NCT01266265   United States
Inhaled treprostinil
   United Therapeutics
      2012   Phase 3   NCT01557660   -
      2012   Phase 3   NCT01557647   -
      2008   Phase 4   NCT00741819   United States
      2005   Phase 3   NCT00147199   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Spain;United Kingdom;United States
INO
   BELLEROPHON PULSE TECHNOLOGIES LLC
      2016   Phase 3   EUCTR2015-005223-90-IT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
   Beijing Children's Hospital, Capital Medical University
      2023   Phase 0   ChiCTR2300070324   China
   Bellerophon Pulse Technologies
      2018   Phase 3   NCT03602781   Canada;United States
   Bellerophon Pulse Technologies LLC
      2018   Phase 3   EUCTR2015-005223-90-BE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-NL   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-HR   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2017   Phase 3   EUCTR2015-005223-90-AT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-PT   Australia;Austria;Belgium;Canada;Croatia;Czech Republic;France;Germany;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-GB   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-DE   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
      2016   Phase 3   EUCTR2015-005223-90-CZ   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
INS1009
   Fraz Ismat
      2023   Phase 2-3   JPRN-jRCT2061220089   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Phillipines;Spain;Switzerland;United Kingdom;United States
   INSMED INCORPORATED
      2023   Phase 2   EUCTR2022-001951-18-IT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-IT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;France;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
   Insmed Incorporated
      2023   Phase 2   EUCTR2022-001951-18-DE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2023   Phase 2   EUCTR2022-001951-18-AT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2022-001951-18-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
Intravenous administration OF ferric carboxymaltose
   University of Oxford
      2013   -   NCT01847352   United Kingdom
Intravenous infusion
   Actelion Pharmaceuticals Japan Ltd.
      2014   Phase 3   JPRN-jRCT2080222671   -
      2014   Phase 3   JPRN-jRCT2080222670   -
      2012   Phase 3   JPRN-jRCT1080221971   -
   VU University Medical Centre
      2006   -   EUCTR2006-002081-19-NL   Netherlands
Intravenous treprostinil
   United Therapeutics
      2005   Phase 4   NCT03055221   -
Intravenous/subcutaneous treprostinil
   United Therapeutics
      2019   Phase 4   NCT03497689   United States
Iron supplement
   The Cleveland Clinic
      2012   -   NCT01446848   United States
Jardiance
   Amsterdam UMC, location VUmc
      2023   Phase 2   EUCTR2022-002400-20-NL   Netherlands
JNJ-67896049
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-002817-21-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 4   EUCTR2019-004783-22-NL   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-GB   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-FR   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-DE   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
   Actelion
      2021   Phase 4   NCT04435782   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Italy;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2021   Phase 3   EUCTR2019-002817-21-FI   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-PT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-LT   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-HU   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-ES   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-DE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-BE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2019   Phase 3   EUCTR2019-002817-21-PL   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-SE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2019-002817-21-IE   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-FR   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
JNJ-67896062 / ACT-064992
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
   ACTELION Pharmacteuticals Ltd.
      2021   Phase 3   EUCTR2019-002533-11-BG   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Türkiye;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PL   Argentina;Australia;Austria;Belgium;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-NO   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-NL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-HU   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-GB   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-FR   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-DK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-DE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-CZ   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-BE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
JNJ-67896062/ACT-064922
   ACTELION Pharmacteuticals Ltd.
      -   Phase 1   EUCTR2022-002754-74-PL   Germany;Poland
      -   Phase 1   EUCTR2022-002754-74-DE   Germany;Poland
JTT-251
   Akros Pharma Inc.
      2019   Phase 2   NCT03789643   -
KAR5585 capsules
   Karos Pharmaceuticals
      2015   Phase 1   NCT02746237   United States
L-carnitine
   Vanderbilt University Medical Center
      2021   Phase 1   NCT04908397   United States
L-citrulline malate
   Masih Daneshvari Hospital
      2012   Phase 0   NCT01683981   Iran, Islamic Republic of
L01xe01
   Aerovate Therapeutics, Inc.
      2022   Phase 2;Phase 3   EUCTR2021-001910-13-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Colombia;Czech Republic;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Singapore;South Africa;Spain;Sweden;Turkey;United Kingdom;United States
L606 (liposomal treprostinil) inhalation solution 51UG
   Pharmosa Biopharm Inc.
      2018   Phase 1   NCT04041648   United States
L606 inhalation system
   Pharmosa Biopharm Inc.
      2018   Phase 1   NCT04041648   United States
L608 inhalation solution
   Pharmosa Biopharm Inc.
      2023   Phase 1   NCT05938946   Australia
L608 liposomal inhalation solution
   Pharmosa Biopharm Inc.
      2024   Phase 1   NCT06429930   New Zealand
Levitra
   Rabin Medical Center
      2012   Phase 4   NCT01649739   Israel
Lidocaine
   Jewish General Hospital
      2012   Phase 4   NCT01433328   Canada
Light transmission aggregometry
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
LIQ861 100 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-FR   France;Germany
LIQ861 106 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
LIQ861 25 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-FR   France;Germany
LIQ861 26.5 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
LIQ861 50 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-FR   France;Germany
LIQ861 53 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
LIQ861 75 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-FR   France;Germany
LIQ861 79.5 µG
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
LIQ861 inhaled treprostinil
   Liquidia Technologies, Inc.
      2019   Phase 3   NCT03992755   United States
      2018   Phase 3   NCT03399604   United States
Lisuride
   Sinoxa Pharma GmbH
      2012   -   EUCTR2012-001675-37-DE   Austria;Germany
      2012   -   EUCTR2012-001675-37-AT   Austria;Germany
LTP
   Novartis Pharmaceuticals
      2024   Phase 1/Phase 2   NCT06649110   United States
LTP001
   Novartis Farmacéutica, S.A.
      2022   Phase 2   EUCTR2021-000670-28-ES   Argentina;Germany;Netherlands;Poland;Russian Federation;Spain;United Kingdom;United States
   Novartis Pharma AG
      2023   Phase 2   EUCTR2022-002007-38-NL   Argentina;Germany;Netherlands;Poland;Spain;United Kingdom;United States
      2022   Phase 2   EUCTR2021-000670-28-NL   Argentina;Germany;Netherlands;Poland;Russian Federation;Spain;United Kingdom;United States
      2022   Phase 2   EUCTR2021-000670-28-DE   Argentina;Germany;Netherlands;Poland;Russian Federation;Spain;United Kingdom;United States
   Novartis Pharmaceuticals
      2023   Phase 2   NCT05764265   Argentina;Germany;Netherlands;Poland;Spain;United Kingdom;United States
      2022   Phase 2   NCT05135000   Argentina;Germany;Netherlands;Poland;Spain;United Kingdom;United States
LY450190
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Macitentan
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   ACTELION Pharmaceuticals France
      2015   Phase 4   EUCTR2015-002078-19-FR   France
   ACTELION Pharmaceuticals Ltd
      2019   Phase 3   EUCTR2016-001062-28-FI   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      2017   Phase 3   EUCTR2016-001062-28-PT   Argentina;Australia;Austria;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Romania;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      2017   Phase 3   EUCTR2016-001062-28-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Finland;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
      2017   Phase 3   EUCTR2016-001062-28-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
      2017   Phase 3   EUCTR2016-001062-28-AT   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2016-001062-28-PL   Australia;Austria;Brazil;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2016-001062-28-FR   Australia;Austria;Canada;China;Colombia;Finland;France;Germany;Hungary;Israel;Korea, Republic of;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2014   Phase 3   EUCTR2013-003489-15-ES   Italy;Spain
      2014   -   EUCTR2013-003462-14-ES   Spain
      2013   Phase 3   EUCTR2013-003489-15-IT   Italy;Spain
      2013   Phase 3   EUCTR2013-003462-14-IT   Italy;Spain
   ACTELION Pharmacteuticals Ltd.
      2020   Phase 3   EUCTR2019-002533-11-AT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      -   Phase 1   EUCTR2022-002754-74-PL   Germany;Poland
      -   Phase 1   EUCTR2022-002754-74-DE   Germany;Poland
   Actelion
      2024   Phase 1   NCT05731492   Germany;Poland
      2018   Phase 3   NCT03422328   Belarus;Belgium;France;Poland;Russian Federation;Turkey;Ukraine
      2017   Phase 3   NCT02932410   Argentina;Australia;Austria;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
      2016   Phase 3   NCT02558231   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2015   Phase 4   NCT02968901   France
      2015   Phase 4   NCT02310672   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2014   -   NCT02126943   Puerto Rico;United States
      2014   Phase 3   NCT02112487   France;Italy;Spain
      2014   Phase 3   NCT02081690   France;Italy;Spain
      2013   Phase 3   NCT01847014   United States
      2013   Phase 3   NCT01841762   United States
      2008   Phase 3   NCT00667823   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Czech Republic;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   NCT00660179   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Czech Republic;Denmark;Finland;Former Serbia and Montenegro;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Norway;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
      2018   Phase 3   EUCTR2017-003934-10-FR   Belgium;France;Poland
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2007-003694-27-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2011   -   EUCTR2007-003694-27-GB   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-DE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-AT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2015   Phase 4   EUCTR2014-004066-20-NL   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-GB   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-DE   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-NL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      2008   Phase 3   EUCTR2007-003694-27-BE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
      -   Phase 3   EUCTR2007-003694-27-PL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Janssen Pharmaceutical K.K.
      2022   Phase 3   NCT05167825   Japan
      -   Phase 3   EUCTR2023-000984-30-Outside-EU/EEA   Japan
   Justus Liebig Universität Gießen
      2016   Phase 2   EUCTR2015-002835-17-DE   Germany
   Nakano Masayoshi
      2022   Phase 3   JPRN-jRCT2011210057   -
   Nippon Shinyaku co.,LTD./Actelion Pharmaceuticals Japan Ltd.
      2012   Phase 2-3   JPRN-jRCT2080221941   -
   VU University Medical Center
      2013   Phase 4   NCT03236818   Netherlands
Macitentan 10 MG
   Actelion
      2020   Phase 3   NCT04273945   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Greece;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2019   Phase 3   NCT03904693   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2013   Phase 3   NCT01743001   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Greece;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Philippines;Poland;Portugal;Romania;Russian Federation;Serbia;South Africa;Spain;Taiwan;Turkey;United Kingdom;United States;Vietnam
      2013   Phase 3   NCT01739400   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Greece;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Philippines;Poland;Portugal;Romania;Russian Federation;Serbia;South Africa;Spain;Taiwan;Turkey;United Kingdom;United States;Vietnam
   Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
      2019   -   JPRN-UMIN000035389   Japan
   Janssen Pharmaceutical K.K.
      2020   Phase 3   JPRN-jRCT2080224886   Europe;Japan;South America
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2061200058   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic Of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden
Macitentan 37.5 MG
   Actelion
      2020   Phase 3   NCT04273945   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Greece;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2061200058   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic Of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden
Macitentan 75 MG
   Actelion
      2020   Phase 3   NCT04273945   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Greece;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;South Africa;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2061200058   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic Of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden
Macitentan compresse
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
Macitentan group
   University of Giessen
      2018   Phase 2   NCT03362047   Germany
Macitentan tablets
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
   ACTELION Pharmacteuticals Ltd.
      2021   Phase 3   EUCTR2019-002533-11-BG   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Türkiye;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PL   Argentina;Australia;Austria;Belgium;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-NO   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-NL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-HU   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-GB   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-FR   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-DK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-DE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-CZ   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-BE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
Macitentan tablets
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 3   EUCTR2019-004131-24-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
Medical AIR
   George Papanicolaou Hospital
      2018   -   NCT03683082   Greece
Melatonin
   Ain Shams University
      2024   Phase 3   NCT06685679   Egypt
Metformin
   Nantes University Hospital
      2011   Phase 2   NCT01352026   France
   Vanderbilt University Medical Center
      2018   Phase 2   NCT03617458   United States
Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   Phase 2   EUCTR2010-018863-40-GB   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-B]pyridine-3-YL]-5-pyrimidinyl(methyl)carb
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-B]pyridin-3-YL]-5-pyrimidinyl]meth
   Bayer HealthCare AG
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
Methylprednisolone
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
Mhealth intervention
   Vanderbilt University Medical Center
      2018   Phase 2   NCT03617458   United States
MK-4836
   Thoraxklinik Heidelberg gGmbH
      2023   Phase 2   EUCTR2021-001633-40-IT   Austria;France;Germany;Italy;Switzerland;United Kingdom
      2022   Phase 2   EUCTR2021-001633-40-DE   Austria;France;Germany;Italy;Norway;Switzerland;United Kingdom
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
MK-5475
   MERCK SHARP & DOHME CORP. UNA SUSSIDIARIA DI MERCK & CO. INC.
      2021   Phase 2;Phase 3   EUCTR2020-001108-40-IT   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Sweden;Turkey;United Kingdom;United States
   Merck Sharp & Dohme Corp.
      2019   Phase 1   NCT03744637   Moldova, Republic of
   Merck Sharp & Dohme Corp., a subsidiary of Merck &Co.,Inc
      2021   Phase 2;Phase 3   EUCTR2020-001108-40-GR   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;Mexico;New Zealand;Poland;Russian Federation;Sweden;Turkey;United Kingdom;United States
      2021   Phase 2;Phase 3   EUCTR2020-001108-40-FR   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Sweden;Turkey;United Kingdom;United States
   Merck Sharp & Dohme LLC
      2022   Phase 2;Phase 3   EUCTR2020-001108-40-BE   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;Mexico;New Zealand;Poland;Russian Federation;Sweden;Turkey;United Kingdom;United States
      2021   Phase 2/Phase 3   NCT04732221   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;Mexico;New Zealand;Poland;Russian Federation;Sweden;Turkey;United Kingdom;United States
      2021   Phase 2;Phase 3   EUCTR2020-001108-40-PL   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Sweden;Turkey;United Kingdom;United States
      2021   Phase 2;Phase 3   EUCTR2020-001108-40-DE   Argentina;Australia;Belgium;Canada;Colombia;France;Germany;Greece;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Sweden;Turkey;United Kingdom;United States
MK-7962
   Merck Sharp & Dohme LLC
      2023   Phase 2   EUCTR2022-000478-25-NL   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2022-000478-25-FR   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2022-000478-25-DE   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 2   EUCTR2022-000478-25-PL   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 2   EUCTR2022-000478-25-ES   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
   Tanaka Yoshiyuki
      2023   Phase 3   JPRN-jRCT2031230046   -
MK-8892
   Merck Sharp & Dohme Corp.
      2013   Phase 1   NCT01934647   Germany
      2013   Phase 1   NCT01926509   Bulgaria;Germany;Moldova, Republic of
      2013   Phase 1   NCT01798849   Belgium
MN-08 24 MG/DAY
   Guangzhou Magpie Pharmaceuticals Co., Ltd.
      2025   Phase 1   NCT05660863   -
MN-08 60 MG/DAY
   Guangzhou Magpie Pharmaceuticals Co., Ltd.
      2025   Phase 1   NCT05660863   -
MONO-therapy with sildenafil
   Johns Hopkins University
      2022   Phase 3   NCT04039464   Canada;United States
Morphine sulfate
   John Granton
      2017   Phase 2   NCT03401476   Canada
Moxifloxacin 400 MG
   Bial - Portela C S.A.
      2018   Phase 1   NCT03489005   United Kingdom
MTT with antibiotic preconditioning + fiber supplementation
   University of Minnesota
      2024   Phase 1   NCT06481852   United States
Multihance
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
Nebulized combination ipratropium bromide with salbutamol
   Assistance Publique - Hôpitaux de Paris
      2016   Phase 3   NCT02782052   -
Nebulized ipratropium bromide
   Assistance Publique - Hôpitaux de Paris
      2016   Phase 3   NCT02782052   -
NEW thermo stable formulation OF epoprostenol sodium
   GlaxoSmithKline
      2011   Phase 4   NCT01462565   Canada;Netherlands;United States
Nicardipine
   Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
      1999   -   JPRN-UMIN000020386   Japan
Nilotinib
   NOVARTIS FARMA
      2010   -   EUCTR2010-019883-36-IT   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;United States
   Novartis Pharma AG
      2010   -   EUCTR2010-019883-36-HU   Germany;Hungary
   Novartis Pharmaceuticals
      2010   Phase 2   NCT01179737   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;Switzerland;United States
Nilotinib 50 MG
   Novartis Pharma Services AG
      2011   -   EUCTR2010-019883-36-DE   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;Switzerland;United States
Nitric oxide
   Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
      2016   Phase 2   NCT02734953   United States
   Beijing Children's Hospital, Capital Medical University
      2023   Phase 0   ChiCTR2300070324   China
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
   Ogo Takeshi
      2022   Phase 2   JPRN-jRCT2051220042   -
   Wake Forest University Health Sciences
      2010   Phase 2   NCT01165047   United States
Nitric oxide FOR inhalation
   Mallinckrodt
      2004   Phase 3   NCT00626028   France;Netherlands;Spain;United Kingdom;United States
Nitric oxide generated BY THE geno nitrosyl delivery system
   Geno LLC
      2010   Phase 2   NCT01092559   United States
Nitric oxide plus oxygen
   Mallinckrodt
      2004   Phase 3   NCT00626028   France;Netherlands;Spain;United Kingdom;United States
NON-biologic dmards
   Hoffmann-La Roche
      2000   -   NCT02784808   -
Noninvasive actigraphy monitor
   University of Cincinnati
      2021   -   NCT04451850   United States
NS-304
   Actelion Pharmaceuticals Ltd
      2008   Phase 2   EUCTR2007-006453-12-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-006453-12-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-006453-12-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-HU   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-GB   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   Actelion Pharmaceuticals Ltd.
      2009   Phase 2   EUCTR2007-006453-12-AT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   NIPPON SHINYAKU CO., LTD.
      2008   Phase 2   EUCTR2007-006453-12-IT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   -   EUCTR2007-003328-39-IT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
      2011   Phase 2   JPRN-jRCT2080221493   -
   Nippon Shinyaku Co., LTD
      2009   -   EUCTR2007-003328-39-AT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-003328-39-FR   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
   Nippon Shinyaku Co., Ltd.
      2020   Phase 2   JPRN-jRCT2080225295   Japan
      2008   Phase 2   EUCTR2007-006453-12-FR   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
NX1011
   NITROX, LLC
      2006   Phase 2   NCT00323024   United States
Observational study with patients treated with tracleer, ventavis, veletri, opsumit and/or uptravi
   Actelion
      2011   -   NCT01389206   Puerto Rico;United States
Olaparib
   Laval University
      2019   Phase 1/Phase 2   NCT03782818   Canada
      2018   Early Phase 1   NCT03251872   Canada
Opsumit
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   ACTELION Pharmaceuticals France
      2015   Phase 4   EUCTR2015-002078-19-FR   France
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
   ACTELION Pharmacteuticals Ltd.
      2021   Phase 3   EUCTR2019-002533-11-BG   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-SE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Türkiye;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-PL   Argentina;Australia;Austria;Belgium;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-NO   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-NL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-HU   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-GB   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2020   Phase 3   EUCTR2019-002533-11-FR   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Romania;Russian Federation;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-002533-11-DK   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-DE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-CZ   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002533-11-BE   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
   Actelion
      2014   -   NCT02126943   Puerto Rico;United States
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
      2018   Phase 3   EUCTR2017-003934-10-FR   Belgium;France;Poland
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2012   Phase 3   EUCTR2007-003694-27-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2015   Phase 4   EUCTR2014-004066-20-NL   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-GB   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      2015   Phase 4   EUCTR2014-004066-20-DE   Australia;France;Germany;Hong Kong;Israel;Italy;Malaysia;Netherlands;Russian Federation;Singapore;United Kingdom;United States
      -   Phase 3   EUCTR2007-003694-27-PL   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;Chile;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hong Kong;Hungary;India;Israel;Italy;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;Slovakia;South Africa;Sweden;Taiwan;Thailand;Ukraine;United Kingdom;United States
   Justus Liebig Universität Gießen
      2016   Phase 2   EUCTR2015-002835-17-DE   Germany
Opsumit®
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 3   EUCTR2019-004131-24-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
   ACTELION Pharmacteuticals Ltd.
      2020   Phase 3   EUCTR2019-002533-11-AT   Argentina;Australia;Austria;Belarus;Belgium;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Portugal;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States;Viet Nam
Optional muscle biopsy
   Mayo Clinic
      2023   Phase 2   NCT05564637   United States
Oral anticoagulant treatment
   Centre Hospitalier Universitaire de Saint Etienne
      2017   -   NCT02800941   France
Oral ERA
   United Therapeutics
      2010   -   NCT01266265   United States
Oral ifetroban
   Cumberland Pharmaceuticals
      2017   Phase 2   NCT02682511   India;United States
Oral PDE5 inhibitors
   United Therapeutics
      2010   -   NCT01266265   United States
Oral sildenafil
   University of Chile
      2003   Phase 4   NCT00483626   Chile
Oral treprostinil
   United Therapeutics
      2022   Phase 4   NCT05203510   United States
      2019   Phase 4   NCT03497689   United States
      2017   -   NCT03045029   United States
      2017   Phase 2   NCT03016468   -
      2017   Phase 3   NCT02999906   -
      2014   Phase 2   NCT02276872   United States
Oral treprostinil (UT-15C) sustained release tablets
   United Therapeutics
      2006   Phase 3   NCT00325442   Australia;Austria;Belgium;Canada;France;Germany;Ireland;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
      2006   Phase 3   NCT00325403   Austria;Belgium;Canada;China;France;India;Israel;Italy;Mexico;Netherlands;Poland;Puerto Rico;United States
Oral zamicastat
   Bial - Portela C S.A.
      2019   Phase 2   NCT06009185   Austria;Germany;Italy;Portugal;Spain;United Kingdom
Ossido nitrico
   BELLEROPHON PULSE TECHNOLOGIES LLC
      2016   Phase 3   EUCTR2015-005223-90-IT   Australia;Austria;Belgium;Canada;Colombia;Croatia;Czech Republic;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Netherlands;Portugal;Serbia;Spain;Ukraine;United Kingdom;United States
Oxacom
   National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
      2024   Phase 2/Phase 3   NCT06683040   Russian Federation
Oxygen
   Heidelberg University
      2019   Phase 2   NCT04207593   Germany
   University of Zurich
      2023   -   NCT06003244   Switzerland
Oxygen supplementation
   George Papanicolaou Hospital
      2018   -   NCT03683082   Greece
Oxygen, liquid
   Thoraxklinik-Heidelberg gGmbH
      2019   Phase 2   EUCTR2018-001387-39-DE   Germany
PAH
   Tamura Yuichi
      2022   Phase 2   JPRN-jRCT2031210626   -
PAH medication
   Bayer
      2019   -   NCT03863990   Argentina
   Janssen-Cilag S.p.A.
      2020   -   NCT04567602   Italy
Parenteral remodulin (treprostinil) injection
   United Therapeutics
      2017   Phase 2   NCT03016468   -
Parenteral treprostinil
   United Therapeutics
      2022   Phase 4   NCT05203510   United States
Passive LEG raising
   Shanghai Zhongshan Hospital
      2022   -   NCT05587400   China
PB1046 subcutaneous injection
   PhaseBio Pharmaceuticals Inc.
      2017   Phase 1   NCT03315507   United States
PB1046, VIP-ELP1-120, vasomera
   PhaseBio Pharmaceuticals, Inc.
      2021   Phase 2   EUCTR2019-001598-10-AT   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-PL   Austria;Belgium;Bulgaria;Czechia;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-HU   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-GR   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-ES   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-BG   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
PDE5 inhibitor
   Brigham and Women's Hospital
      2021   -   NCT05039086   United States
Pemziviptadil (PB1046) injection
   PhaseBio Pharmaceuticals Inc.
      2019   Phase 2   NCT03795428   United States
PET-CT imaging with [89ZR]-bevacizumab
   Brigham and Women's Hospital
      2018   Phase 1/Phase 2   NCT03166306   United States
PET/CT scan: TWO PET scans using 1. C-11 HED and 2. N-13 ammonia or rubidium-82
   Ottawa Heart Institute Research Corporation
      2018   Phase 4   NCT03344159   Canada
PF-00489791
   Pfizer
      2009   Phase 2   NCT00853112   Belgium;Canada;Germany;India;Russian Federation;Spain;Sweden;Switzerland;United States
   Pfizer Ltd,Ramsgate Road,Sandwich,Kent CT13 9NJ
      2009   -   EUCTR2008-003572-21-SE   Belgium;Germany;Spain;Sweden
      2009   -   EUCTR2008-003572-21-BE   Belgium;Germany;Spain;Sweden
   Pfizer Ltd.
      2009   -   EUCTR2008-003572-21-DE   Belgium;Germany;Spain;Sweden
   Pfizer, S.A.
      2009   Phase 2   EUCTR2008-003572-21-ES   Belgium;Germany;Spain;Sweden
PF-07868489
   Pfizer
      2023   Phase 1/Phase 2   NCT06137742   China;Japan;Korea, Republic of;United Kingdom;United States
Pioglitazone
   Stanford University
      2008   Phase 2   NCT00825266   United States
Platelet function analyzer-100
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
PLX-PAD
   United Therapeutics
      2013   Phase 1   NCT01795950   Australia
Prednisone
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
Preservative-free parenteral treprostinil
   AOP Orphan Pharmaceuticals AG
      2024   Phase 3   NCT06350032   Austria;France;Hungary;Spain
Prostacyclin
   Hamamatsu University School of Medicine
      2017   -   JPRN-UMIN000025176   Japan
Prostacyclin receptor agonist
   Actelion
      2022   Phase 1   NCT05427162   United States
PURI-nethol
   VU University Medical Center
      2017   Phase 2   EUCTR2017-000137-31-NL   Netherlands
QCC374
   Novartis Pharmaceuticals
      2018   Phase 2   NCT02939599   Germany;United Kingdom;United States
      2017   Phase 2   NCT02927366   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
QCC374 0.015 MG
   Novartis Pharma AG
      2018   Phase 2   EUCTR2016-001411-20-GB   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001412-38-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001411-20-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
QCC374 0.06 MG
   Novartis Pharma AG
      2018   Phase 2   EUCTR2016-001411-20-GB   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001412-38-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001411-20-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
QTI571
   NOVARTIS FARMA
      2011   -   EUCTR2010-021960-14-IT   Germany;Italy
      2011   -   EUCTR2010-021344-17-IT   Italy
      2010   -   EUCTR2009-018167-26-IT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
   Novartis Farmacéutica, S.A.
      2013   -   EUCTR2013-001100-10-ES   Australia;Spain;Switzerland;United States
   Novartis Pharma AG
      2011   -   EUCTR2010-021960-14-DE   Germany;Italy
      2010   Phase 3   EUCTR2009-018167-26-GB   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-FR   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-018167-26-DE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   Phase 3   EUCTR2009-018167-26-BE   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2010   -   EUCTR2009-012057-38-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharma K.K.
      2014   Phase 3   JPRN-jRCT2080222412   -
   Novartis Pharma Services AG
      2010   -   EUCTR2009-018167-26-AT   Austria;Belgium;France;Germany;Italy;Spain;United Kingdom
      2009   -   EUCTR2009-012057-38-SE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-012057-38-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
   Novartis Pharmaceuticals
      2014   Phase 3   NCT02042014   Japan
Qutenza
   Imperial College London
      2011   Phase 2   NCT01393795   United Kingdom
      2011   -   EUCTR2011-001312-59-GB   United Kingdom
   University of Rochester
      2010   Phase 2   NCT01260454   United States
Ralinepag
   Arena Pharmaceuticals, Inc.
      2023   Phase 3   EUCTR2018-001189-40-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2018-001187-33-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-RO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2017   Phase 2   EUCTR2014-000667-40-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2016   Phase 2   EUCTR2014-003042-27-SK   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-003042-27-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   -   EUCTR2014-003042-27-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   -   EUCTR2014-000667-40-RO   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-PL   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-HU   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-ES   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
      2015   Phase 2   EUCTR2014-000667-40-CZ   Australia;Bulgaria;Czech Republic;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
   UNITED THERAPEUTICS CORPORATION
      2020   Phase 3   EUCTR2019-003309-88-IT   Argentina;Australia;Austria;Belgium;Brazil;Czechia;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
   United Therapeutics
      2021   Phase 3   NCT04084678   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Spain;United Kingdom;United States
      2019   Phase 3   NCT03683186   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czechia;Denmark;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   NCT03626688   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czechia;Denmark;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Spain;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2015   Phase 2   NCT02279745   Australia;Bulgaria;Czechia;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
   United Therapeutics Corporation
      2022   Phase 3   EUCTR2019-003309-88-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Singapore;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-PL   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-GB   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-ES   Argentina;Australia;Austria;Belgium;Brazil;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-DE   Argentina;Australia;Austria;Belgium;Brazil;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2019-003309-88-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Germany;Italy;Poland;Portugal;Spain;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2018-001189-40-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-SE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-RO   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Türkiye;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-GB   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001189-40-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-SE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Denmark;European Union;Germany;Greece;Hungary;Israel;Korea, Republic of;Mexico;Netherlands;Portugal;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-HR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-GB   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DK   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-001187-33-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   EUCTR2018-001187-33-CZ   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;Chile;China;Croatia;Czech Republic;Denmark;European Union;France;Germany;Greece;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Romania;Serbia;Singapore;Sweden;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2014-003042-27-CZ   Australia;Bulgaria;Czech Republic;Czechia;Hungary;Poland;Romania;Serbia;Slovakia;Spain;United States
Ranolazine
   Northwestern University
      2010   Phase 3   NCT01174173   United States
   University of Chicago
      2011   Phase 1   NCT01757808   United States
Rapamycin
   Aadi Bioscience, Inc.
      2017   Phase 1   NCT02587325   United States
Rapid dose titration group OF subcutaneous treprostinil
   United Therapeutics
      2017   Phase 4   NCT02893995   China
Recombinant human angiotensin-converting enzyme 2 (ACE2), APN01
   GlaxoSmithKline Research & Development Ltd
      2017   Phase 2   EUCTR2017-000212-41-DE   Germany;Spain;United States
   GlaxoSmithKline, S.A.
      2017   Phase 2   EUCTR2017-000212-41-ES   Germany;Spain;United States
Remodulin
   Medtronic Cardiac Rhythm and Heart Failure
      2020   -   NCT03833323   -
   United Therapeutics
      2012   Phase 4   NCT02847260   -
      2005   Phase 4   NCT00494533   India
Remodulin® (treprostinil) 1 MG/ML solution FOR infusion
   United Therapeutics Corp.
      2012   -   EUCTR2011-004631-31-DE   Germany
Remodulin® (treprostinil) 10 MG/ML solution FOR infusion
   United Therapeutics Corp.
      2012   -   EUCTR2011-004631-31-DE   Germany
Remodulin® (treprostinil) 2.5 MG/ML solution FOR infusion
   United Therapeutics Corp.
      2012   -   EUCTR2011-004631-31-DE   Germany
Remodulin® (treprostinil) 5 MG/ML solution FOR infusion
   United Therapeutics Corp.
      2012   -   EUCTR2011-004631-31-DE   Germany
Revatio
   Actelion Pharmaceuticals Ltd.
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
   Deutsches Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
      2007   -   EUCTR2007-002774-64-DE   Germany
   NOVARTIS FARMA
      2011   -   EUCTR2010-021344-17-IT   Italy
   PFIZER
      2008   -   EUCTR2006-006748-76-IT   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2014   -   EUCTR2013-004362-34-RO   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-PL   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-GR   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-ES   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2009   -   EUCTR2008-005886-78-BG   Bulgaria;Czech Republic
   Pfizer Japan Inc
      -   -   EUCTR2014-004167-20-Outside-EU/EEA   Japan
   Pfizer Limited, Ramsgate Road, Sandwich, Kent UK
      2009   Phase 3   EUCTR2008-005886-78-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2009   Phase 3   EUCTR2008-005887-14-SK   Bulgaria;Czech Republic;Slovakia
      2009   -   EUCTR2008-005887-14-BG   Bulgaria;Czech Republic
      2007   Phase 3   EUCTR2005-000963-25-SK   Finland;Slovakia;Sweden;United Kingdom
      2007   -   EUCTR2005-000963-25-FI   Finland;Sweden;United Kingdom
      2006   Phase 3   EUCTR2005-000963-25-GB   Finland;Slovakia;Sweden;United Kingdom
      2005   -   EUCTR2005-000963-25-SE   Brazil;Chile;Colombia;Costa Rica;Finland;Guatemala;Hungary;India;Italy;Malaysia;Mexico;Poland;Russian Federation;Sweden;Taiwan;Thailand;United Kingdom
      -   -   EUCTR2005-000963-25-Outside-EU/EEA   Brazil;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Russian Federation;Taiwan;United States
   Pfizer Ltd
      2006   Phase 4   EUCTR2006-001464-23-GB   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
      2007   Phase 3   EUCTR2006-002235-25-SK   Finland;Slovakia;United Kingdom
      2007   -   EUCTR2006-002235-25-FI   Finland;United Kingdom
      2006   Phase 3   EUCTR2006-002235-25-GB   Finland;Slovakia;United Kingdom
      -   -   EUCTR2006-002235-25-Outside-EU/EEA   Brazil;Canada;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Peru;Russian Federation;Taiwan;United States
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent UK
      2008   -   EUCTR2006-006748-76-DK   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-BE   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
      2009   -   EUCTR2006-006748-76-BG   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-LV   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   Phase 4   EUCTR2006-006748-76-GB   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2006   -   EUCTR2006-001464-23-DE   Australia;Belgium;Czech Republic;France;Germany;Greece;Israel;Italy;Taiwan;United Kingdom
   Pfizer Ltd,Ramsgate Road,Sandwich CT13 9NJ
      2008   -   EUCTR2006-001464-23-GR   Czech Republic;Germany;Greece;Italy;United Kingdom
      2006   -   EUCTR2006-001464-23-CZ   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer Ltd,Ramsgate Road,Sandwich,Kent CT13 9NJ
      2009   -   EUCTR2008-003572-21-SE   Belgium;Germany;Spain;Sweden
      2009   -   EUCTR2008-003572-21-BE   Belgium;Germany;Spain;Sweden
   Pfizer Ltd.
      2010   -   EUCTR2008-005887-14-CZ   Bulgaria;Czech Republic
      2010   Phase 3   EUCTR2008-005886-78-CZ   Bulgaria;Czech Republic
   Pfizer Ltd. Ramsgate Road, Sandwich, Kent, UK
      2008   -   EUCTR2006-006748-76-NL   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-GR   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer, Ltd.
      -   -   EUCTR2015-002238-37-Outside-EU/EEA   India
Revatio 10 MG/ML powder FOR oral suspension
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
Revatio 20 MG film coated tablets
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
Revatio 20 MG FILM-coated tablets
   Bayer AG
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Revatio 20 MG filmtabletten
   Pfizer Ltd.
      2009   -   EUCTR2008-003572-21-DE   Belgium;Germany;Spain;Sweden
Revatio 20 MG, comprimidos recubiertos CON PELícula
   Pfizer, S.A.
      2009   Phase 2   EUCTR2008-003572-21-ES   Belgium;Germany;Spain;Sweden
Revatio inyectable
   Fundacion para la investigación Biomédica del hospital Gregorio Marañón
      2014   -   EUCTR2011-002707-16-ES   Spain
Revatio oral
   Fundacion para la investigación Biomédica del hospital Gregorio Marañón
      2014   -   EUCTR2011-002707-16-ES   Spain
Revatio POS
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
Revatio tablets
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
Riciguat group
   University of Giessen
      2018   Phase 2   NCT03362047   Germany
Rifampin
   Pfizer
      2010   Phase 1   NCT01251835   -
Right heart catheterization (RHC) while exercising
   Mayo Clinic
      2023   Phase 2   NCT05564637   United States
Riociguat
   BAYER AG
      2016   Phase 4   EUCTR2016-001067-36-IT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer
      2021   -   NCT04813926   Puerto Rico;United States
      2017   Phase 4   NCT02891850   Australia;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   NCT02759419   France;Italy;Korea, Republic of;Poland;Thailand
      2015   Phase 3   NCT02562235   Belgium;Brazil;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2015   -   NCT02428985   Japan
      2014   Phase 4   NCT02191137   Puerto Rico;United States
      2014   Phase 3   NCT02007629   Belgium;Canada;Czech Republic;Czechia;France;Germany;Italy;Switzerland;United Kingdom;United States
      2010   Phase 2   NCT01179334   Austria;Czech Republic;Germany;Italy;New Zealand;Poland;Spain;United Kingdom;United States
      2009   Phase 3   NCT00863681   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   NCT00810693   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 3   EUCTR2014-003952-29-BE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-GB   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-DE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-CZ   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
   Bayer Health Care AG
      2011   -   EUCTR2010-018863-40-AT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-IT   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
   Bayer HealthCare AG
      2014   Phase 3   EUCTR2013-001759-10-IT   Belgium;Canada;Czech Republic;Germany;Italy;Switzerland;United Kingdom;United States
      2014   Phase 2;Phase 3   EUCTR2013-001759-10-FR   Belgium;Canada;Czech Republic;France;Germany;Italy;Switzerland;United Kingdom;United States
      2013   Phase 2;Phase 3   EUCTR2013-001759-10-BE   Belgium;Canada;Czech Republic;Germany;Switzerland;United Kingdom;United States
      2011   -   EUCTR2011-001893-24-DE   Germany
      2011   -   EUCTR2010-018863-40-PL   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   Phase 2   EUCTR2010-018863-40-GB   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2011   -   EUCTR2010-018863-40-ES   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-DE   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   -   EUCTR2010-018863-40-CZ   Austria;Czech Republic;Germany;Italy;Poland;Spain;United Kingdom
      2010   Phase 3   EUCTR2008-003610-94-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   -   EUCTR2008-003482-68-GR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003610-94-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003610-94-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003610-94-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2008-003482-68-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003482-68-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2008-003610-94-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003610-94-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
      2008   Phase 3   EUCTR2008-003482-68-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003482-68-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;Singapore;Spain;Sweden;Switzerland;Taiwan;Thailand;United Kingdom;United States
      2009   -   EUCTR2008-003482-68-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2008-003482-68-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2008-003482-68-SE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer Healthcare AG
      2009   -   EUCTR2008-003482-68-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Greece;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
   Bayer Yakuhin, Ltd.
      2017   Phase 3   JPRN-jRCT2080223235   Asia except Japan;Europe;Japan;North America;South America
   Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
      2019   -   JPRN-UMIN000035389   Japan
   Heidelberg University
      2022   Phase 4   NCT04954742   Germany
   Justus Liebig Universität Gießen
      2016   Phase 2   EUCTR2015-002835-17-DE   Germany
   Second Xiangya Hospital, Central South University
      2024   Phase 4   ChiCTR2500096733   China
   Sheffield Teaching Hospitals NHS Foundation Trust
      2023   Phase 4   NCT05825417   United Kingdom
   Thoraxklinik Heidelberg gGmbH
      2023   Phase 2   EUCTR2021-001633-40-IT   Austria;France;Germany;Italy;Switzerland;United Kingdom
      2022   Phase 2   EUCTR2021-001633-40-DE   Austria;France;Germany;Italy;Norway;Switzerland;United Kingdom
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
Riociguat 0.5 MG
   Bayer AG
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
Riociguat 1.0 MG
   Bayer AG
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
Riociguat 1.5 MG
   Bayer AG
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
Riociguat 2.0 MG
   Bayer AG
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
Riociguat 2.5 MG
   Bayer AG
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
Riociguat film coated tablets
   Humanis Saglik Anonim Sirketi
      2023   Phase 1   NCT06180096   India
Riociguat granules 0.3% FOR oral application
   Bayer AG
      2019   Phase 3   EUCTR2014-003952-29-RO   Belgium;Colombia;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-PL   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003952-29-DE   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-HU   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Taiwan;Turkey;United Kingdom;United States
      2015   Phase 3   EUCTR2014-003952-29-GB   Belgium;Colombia;France;Germany;Hungary;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom;United States
      -   Phase 3   EUCTR2014-003952-29-Outside-EU/EEA   Japan;Turkey
   Bayer Healthcare AG
      2016   Phase 3   EUCTR2014-003952-29-ES   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
      2015   Phase 3   EUCTR2014-003952-29-IT   Australia;Austria;Belgium;Canada;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      -   Phase 3   EUCTR2014-003952-29-FR   Belgium;France;Germany;Hungary;Italy;Japan;Netherlands;Poland;Spain;Turkey;United Kingdom
Riociguat oral product
   University of Calgary
      2016   Phase 4   NCT03809156   Canada
Riociguat oral tablet
   Heidelberg University
      2022   Phase 2   NCT05339087   Austria;France;Germany;Italy;Switzerland;United Kingdom
Riociguat pill
   University of Arizona
      2019   Phase 3   NCT04062565   United States
Ritonavir
   Pfizer
      2011   Phase 1   NCT01251848   -
Rituximab
   Chinese SLE Treatment And Research Group
      2023   Phase 4   NCT05828147   China
   National Institute of Allergy and Infectious Diseases (NIAID)
      2011   Phase 2   NCT01086540   United States
   The University of Tokyo Hospital
      2014   -   JPRN-UMIN000016320   Japan
RO 47-0203
   Actelion Pharmaceuticals Japan Ltd.
      2013   Phase 3   JPRN-jRCT2080222109   -
   Actelion Pharmaceuticals Ltd
      2005   -   EUCTR2005-001967-70-IT   Germany;Italy;United Kingdom
   Actelion Pharmaceuticals Ltd.
      2006   -   EUCTR2004-004391-36-CZ   Czech Republic;Hungary
      2006   -   EUCTR2004-000745-37-GB   Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001967-70-GB   Germany;Italy;United Kingdom
      2005   Phase 3   EUCTR2004-005157-63-GB   Italy;United Kingdom
      2005   -   EUCTR2004-004391-36-HU   Czech Republic;Hungary
      2005   Phase 3   EUCTR2004-000478-30-ES   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 4   EUCTR2004-000745-37-ES   Italy;Spain;United Kingdom
      2004   -   EUCTR2004-000478-30-SE   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 3   EUCTR2004-000478-30-GB   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-DK   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-CZ   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-BE   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-AT   Austria;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      -   -   EUCTR2005-001967-70-DE   Germany;Italy;United Kingdom
RO-47-0203
   Actelion Pharmaceuticals Ltd.
      2008   Phase 4   EUCTR2005-005068-97-ES   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Slovakia;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-DK   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
RO-47-0203/029
   Actelion Pharmaceuticals Ltd.
      2013   Phase 3   EUCTR2010-021825-11-BG   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021825-11-NL   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-NL   Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-HU   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-DE   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-CZ   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-HU   Bulgaria;Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021825-11-DE   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-CZ   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2009   -   EUCTR2005-005068-97-CZ   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2005-005068-97-BE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 4   EUCTR2005-005068-97-SK   Belgium;Brazil;Czech Republic;Denmark;Germany;Greece;Portugal;Saudi Arabia;Slovakia;Spain;Sweden;United Kingdom;United States
      2008   -   EUCTR2005-005068-97-PT   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2005-005068-97-GR   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-SE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-GB   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-DK   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2010-021825-11-FR   Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Spain
      -   Phase 3   EUCTR2010-021793-12-PL   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      -   Phase 3   EUCTR2010-021793-12-FR   Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
Roactemra
   Papworth Hospital NHS Foundation Trust
      2015   Phase 2   EUCTR2015-002799-26-GB   United Kingdom
Rodatristat ethyl
   Altavant Sciences GmbH
      2021   Phase 2   EUCTR2020-004971-42-PL   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-LV   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-IT   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-FR   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-ES   Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-DE   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-CZ   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-BG   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-BE   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-AT   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
Rodatristat ethyl 300 MG tablet BID
   Altavant Sciences GmbH
      2021   Phase 2   NCT04712669   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
Rodatristat ethyl 600 MG BID
   Altavant Sciences GmbH
      2021   Phase 2   NCT04712669   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
Rotational thromboelastometry
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
RT234 - vardenafil inhalation powder
   Respira Therapeutics, Inc.
      2020   Phase 2   NCT04266197   Serbia;United States
      2019   Phase 2   NCT05343637   Australia
RTA 402
   Reata Pharmaceuticals, Inc.
      2016   Phase 3   EUCTR2016-000196-24-NL   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-GB   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-ES   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-DE   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-CZ   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Philippines;Spain;United Kingdom;United States
      2016   Phase 3   EUCTR2016-000196-24-BE   Argentina;Australia;Belgium;Brazil;Canada;Chile;Czech Republic;Germany;Ireland;Israel;Japan;Mexico;Netherlands;Spain;United Kingdom;United States
RVG 33865
   VU university medical center
      2010   -   EUCTR2010-023233-30-NL   Netherlands
RVT-1201
   Altavant Sciences GmbH
      2021   Phase 2   EUCTR2020-004971-42-PL   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-LV   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-IT   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-FR   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-ES   Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-DE   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-CZ   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-BG   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-BE   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States
      2021   Phase 2   EUCTR2020-004971-42-AT   Austria;Belgium;Bosnia and Herzegovina;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Italy;Latvia;Moldova, Republic of;Poland;Serbia;Spain;Ukraine;United Kingdom;United States
      2019   Phase 2   NCT03924154   Canada;United States
Salbutamol
   ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
      2016   Phase 3   EUCTR2014-002590-10-FR   France
Saline
   American Medical Association Foundation
      2014   Phase 2   NCT02108743   United States
   Golden Jubilee National Hospital
      2012   -   NCT01457170   United Kingdom
   Imperial College London
      2012   Phase 1   NCT01590108   United Kingdom
      2011   Phase 2   NCT01447628   China;Germany;United Kingdom
Sapropterin
   Vanderbilt University
      2008   Phase 1   NCT00435331   United States
Saquinavir and ritonavir
   The Third Xiangya Hospital of Central South University
      2013   Phase 0   NCT02023450   China
Satralizumab
   International University of Health and Welfare
      2022   Phase 2   NCT05679570   Japan
   Tamura Yuichi
      2022   Phase 2   JPRN-jRCT2031210626   -
Sauerstoff
   Thoraxklinik-Heidelberg gGmbH
      2019   Phase 2   EUCTR2018-001387-39-DE   Germany
Selexipag
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-002817-21-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 4   EUCTR2019-004783-22-NL   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-GB   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-FR   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-DE   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
   Academic Medical Center - Cardiology
      2016   Phase 3   EUCTR2016-003495-53-NL   Netherlands
   Actelion
      2020   Phase 3   NCT04175600   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Croatia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2018   Phase 2   NCT03492177   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Malaysia;Poland;Romania;Russian Federation;Serbia;Taiwan;Ukraine;United Kingdom;United States
      2017   Phase 4   NCT03078907   Austria;France;Germany;Ireland;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   NCT02558231   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2015   Phase 3   NCT02471183   United States
      2009   Phase 3   NCT01106014   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2018   Phase 2   EUCTR2018-000145-39-HU   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-GB   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-FR   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-DE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 4   EUCTR2017-000216-42-PT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 4   EUCTR2017-000216-42-FR   Austria;France;Germany;Ireland;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-SE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-IE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-GB   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-DE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-AT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 3   EUCTR2016-004035-21-DE   Germany;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2009-014992-31-GB   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   Phase 3   EUCTR2009-014992-31-SK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   Phase 3   EUCTR2009-014992-31-NL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2011   -   EUCTR2009-014490-41-NL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-SE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-PL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-IT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-IE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-HU   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-DK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-DE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-CZ   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-BE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-AT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-SE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-IT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Russian Federation;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-IE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-GB   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-DE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-CZ   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014490-41-BE   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   -   EUCTR2009-014490-41-AT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2009   -   EUCTR2009-014490-41-DK   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2008   Phase 2   EUCTR2007-006453-12-DE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      2008   Phase 2   EUCTR2007-006453-12-BE   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      -   Phase 2   EUCTR2018-000145-39-PL   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      -   Phase 2   EUCTR2018-000145-39-BE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
   Actelion Pharmaceuticals Ltd.
      2021   Phase 3   EUCTR2019-002817-21-FI   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-PT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-LT   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-HU   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-ES   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-DE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-BE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2019   Phase 3   EUCTR2019-002817-21-PL   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2010   -   EUCTR2009-014490-41-HU   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2009   Phase 2   EUCTR2007-006453-12-AT   Austria;Belgium;France;Germany;Hungary;Italy;United Kingdom
      -   Phase 3   EUCTR2019-002817-21-SE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2019-002817-21-IE   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-FR   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
   Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science
      2019   -   JPRN-UMIN000035389   Japan
   Hamamatsu University School of Medicine
      2017   -   JPRN-UMIN000025176   Japan
   NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
      2011   Phase 2   JPRN-jRCT2080221493   -
   Nippon Shinyaku Co., Ltd.
      2020   Phase 2   JPRN-jRCT2080225295   Japan
   Sheffield Teaching Hospitals NHS Foundation Trust
      2023   Phase 4   NCT05825417   United Kingdom
   University of Sao Paulo General Hospital
      2020   Phase 2   NCT04589390   Brazil
Selexipag film coated tablets
   Humanis Saglik Anonim Sirketi
      2025   Phase 1   NCT06932198   Jordan
Selonsertib
   Gilead Sciences
      2014   Phase 2   NCT02234141   Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
Seralutinib
   GB002, Inc.
      2024   Phase 3   NCT06274801   Argentina;Australia;Belgium;Chile;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Serbia;Singapore;Spain;United Kingdom;United States
      2023   Phase 3   NCT05934526   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Romania;Saudi Arabia;Serbia;Singapore;Spain;United Kingdom;United States
      2022   Phase 2   EUCTR2020-005169-15-BE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-ES   Australia;Austria;Belgium;Canada;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2020-005169-15-AT   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-DE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-CZ   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2021   Phase 2   EUCTR2019-002669-37-BE   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-GB   Australia;Austria;Belgium;Canada;France;Germany;Israel;Serbia;Singapore;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-FR   Australia;Austria;Belgium;Canada;France;Germany;Israel;Serbia;Singapore;United Kingdom;United States
      2020   Phase 2   EUCTR2019-002669-37-AT   Australia;Austria;Belgium;Canada;Czech Republic;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
   GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
      2021   Phase 2   NCT04816604   Australia;Belgium;Czechia;France;Germany;Spain;United Kingdom;United States
      2020   Phase 2   NCT04456998   Australia;Austria;Belgium;Canada;Czechia;France;Germany;Israel;Serbia;Spain;United Kingdom;United States
Serine
   Medical Education Center, School of Medicine, Keio University
      2009   -   JPRN-UMIN000001709   Japan
Sham oxygen therapy
   University of Zurich
      2023   -   NCT06084559   Switzerland
Sham padn
   Nanjing First Hospital, Nanjing Medical University
      2014   Phase 4   NCT02284737   China
Sildenaf
   Bayer AG
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Sildenafil
   ASSOCIAZIONE ITALIANA PNEUMOLOGI OSPEDALIERI
      2010   -   EUCTR2010-020917-97-IT   Italy
   Actelion
      2007   Phase 4   NCT00433329   United States
      2006   Phase 3   NCT00302211   United States
   Actelion Pharmaceuticals Ltd
      2006   -   EUCTR2005-005066-37-IT   Germany;Italy;United Kingdom
   Actelion Pharmaceuticals Ltd.
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
   Bayer
      2017   Phase 4   NCT02891850   Australia;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2010   Phase 2   NCT01179334   Austria;Czech Republic;Germany;Italy;New Zealand;Poland;Spain;United Kingdom;United States
   Beijing Chaoyang Hospital affiliated to Capital Medical University
      2014   -   ChiCTR-TRC-14004894   -
   Bial - Portela C S.A.
      2018   Phase 1   NCT04994860   Germany
   Competence Network for Congenital Heart Defects
      2007   Phase 3   NCT00586794   Germany
   Deutsches Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
      2007   -   EUCTR2007-002774-64-DE   Germany
   Division of cardiovascular internal medicine, The University of Tokyo Hospital
      2007   Phase 2,3   JPRN-C000000340   Japan
   Gilead Sciences
      2008   Phase 4   NCT00617305   United States
   Hamamatsu University School of Medicine
      2011   -   JPRN-UMIN000005464   Japan
   Laval University
      2009   -   NCT01391104   Canada
   NOVARTIS FARMA
      2011   -   EUCTR2010-021344-17-IT   Italy
   Nanjing First Hospital, Nanjing Medical University
      2014   Phase 4   NCT02284737   China
   Novartis Pharmaceuticals
      2011   Phase 3   NCT01392469   Australia;Belgium;Germany;Italy;Lithuania;Romania;Turkey;United Kingdom;United States
   Osaka Medical College
      2010   -   JPRN-UMIN000012669   Japan
   PFIZER
      2008   -   EUCTR2006-006748-76-IT   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2006   -   EUCTR2006-001464-23-IT   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer
      2013   -   NCT01897740   Russian Federation
      2010   Phase 1   NCT01244620   Singapore
      2009   Phase 2   NCT00853112   Belgium;Canada;Germany;India;Russian Federation;Spain;Sweden;Switzerland;United States
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2007   Phase 3   EUCTR2005-000963-25-SK   Finland;Slovakia;Sweden;United Kingdom
      2007   -   EUCTR2005-000963-25-FI   Finland;Sweden;United Kingdom
      2006   Phase 3   EUCTR2005-000963-25-GB   Finland;Slovakia;Sweden;United Kingdom
      2005   -   EUCTR2005-000963-25-SE   Brazil;Chile;Colombia;Costa Rica;Finland;Guatemala;Hungary;India;Italy;Malaysia;Mexico;Poland;Russian Federation;Sweden;Taiwan;Thailand;United Kingdom
   Pfizer Ltd
      2006   Phase 4   EUCTR2006-001464-23-GB   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
      2006   -   EUCTR2006-001464-23-DE   Australia;Belgium;Czech Republic;France;Germany;Greece;Israel;Italy;Taiwan;United Kingdom
   Pfizer Ltd,Ramsgate Road,Sandwich CT13 9NJ
      2008   -   EUCTR2006-001464-23-GR   Czech Republic;Germany;Greece;Italy;United Kingdom
      2006   -   EUCTR2006-001464-23-CZ   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2012   Phase 4   NCT01642407   Japan
      2008   Phase 1   NCT00800592   Belgium
      2006   -   NCT00946114   Poland
      2002   Phase 3   NCT00644605   Australia;Belgium;Brazil;Czech Republic;Czechia;Denmark;France;Germany;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Norway;Poland;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
   Pfizer, S.A.
      2009   Phase 2   EUCTR2008-003572-21-ES   Belgium;Germany;Spain;Sweden
   Rigshospitalet
      2006   -   EUCTR2006-000021-57-DK   Denmark
   The Hospital for Sick Children
      2008   Phase 3   NCT00742014   Canada
   University Health Network, Toronto
      2012   Phase 2   NCT01517854   Canada
      2008   Phase 3   NCT00780728   Canada
   University of California, Los Angeles
      2007   Phase 4   NCT00625079   United States
   VU University Medical Center
      2013   Phase 4   NCT03236818   Netherlands
   Viatris Pharmaceuticals Japan Inc
      2017   -   NCT03364244   Japan
Sildenafil (revatio) 20 MG TID
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2008   -   NCT00866983   Brazil
Sildenafil 20MG and bosentan 62.5MG
   Postgraduate Institute of Medical Education and Research
      2016   Phase 4   NCT03053739   India
Sildenafil citrate
   ASSOCIAZIONE ITALIANA PNEUMOLOGI OSPEDALIERI
      2013   -   EUCTR2011-002018-35-IT   Italy
   Actelion Pharmaceuticals Ltd.
      2006   Phase 2   EUCTR2005-005066-37-GB   Belgium;Germany;Italy;United Kingdom
      2006   -   EUCTR2005-005066-37-DE   Germany;Italy;United Kingdom
      2006   -   EUCTR2005-005066-37-BE   Belgium;Germany;Italy;United Kingdom
   Dr. Soetomo General Hospital
      2017   Phase 4   NCT03431649   Indonesia
   Fundacion para la investigación Biomédica del hospital Gregorio Marañón
      2014   -   EUCTR2011-002707-16-ES   Spain
   Keio University
      2008   -   JPRN-UMIN000001350   Japan
   Pfizer
      2008   Phase 4   NCT00430716   Belgium;Brazil;Bulgaria;China;Denmark;Greece;India;Italy;Latvia;Malaysia;Netherlands;Panama;Philippines;Poland;Romania;Russian Federation;Thailand;United Kingdom;United States
      2007   Phase 3   NCT00454207   Japan
      2003   Phase 3   NCT00159913   Australia;Brazil;Canada;Chile;Colombia;Costa Rica;Guatemala;Hungary;India;Italy;Japan;Malaysia;Mexico;Panama;Peru;Poland;Russian Federation;Singapore;Sweden;Taiwan;United States
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2018   Phase 3;Phase 4   EUCTR2013-004362-34-LV   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-SE   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-PT   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Czechia;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-NL   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   -   EUCTR2013-004362-34-HR   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   -   EUCTR2013-004362-34-RO   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-PL   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-GR   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-ES   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-DE   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-CZ   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2014   Phase 3   EUCTR2013-004362-34-BE   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-AT   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2009   -   EUCTR2008-005886-78-BG   Bulgaria;Czech Republic
   Pfizer Japan Inc
      -   -   EUCTR2014-004167-20-Outside-EU/EEA   Japan
   Pfizer Limited, Ramsgate Road, Sandwich, Kent UK
      2009   Phase 3   EUCTR2008-005886-78-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2009   Phase 3   EUCTR2008-005887-14-SK   Bulgaria;Czech Republic;Slovakia
      2009   -   EUCTR2008-005887-14-BG   Bulgaria;Czech Republic
      -   -   EUCTR2005-000963-25-Outside-EU/EEA   Brazil;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Russian Federation;Taiwan;United States
   Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
      2007   Phase 3   EUCTR2006-002235-25-SK   Finland;Slovakia;United Kingdom
      2007   -   EUCTR2006-002235-25-FI   Finland;United Kingdom
      2006   Phase 3   EUCTR2006-002235-25-GB   Finland;Slovakia;United Kingdom
      -   -   EUCTR2006-002235-25-Outside-EU/EEA   Brazil;Canada;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Peru;Russian Federation;Taiwan;United States
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent UK
      2008   -   EUCTR2006-006748-76-DK   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-BE   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
      2009   -   EUCTR2006-006748-76-BG   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-LV   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   Phase 4   EUCTR2006-006748-76-GB   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer Ltd,Ramsgate Road,Sandwich,Kent CT13 9NJ
      2009   -   EUCTR2008-003572-21-BE   Belgium;Germany;Spain;Sweden
   Pfizer Ltd.
      2010   -   EUCTR2008-005887-14-CZ   Bulgaria;Czech Republic
      2010   Phase 3   EUCTR2008-005886-78-CZ   Bulgaria;Czech Republic
   Pfizer Ltd. Ramsgate Road, Sandwich, Kent, UK
      2008   -   EUCTR2006-006748-76-NL   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-GR   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
      2014   Phase 4   NCT02060487   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Czechia;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Thailand;Turkey;Ukraine;United States
      2011   -   NCT01365585   Germany;Ireland
      2009   -   NCT00878943   India
      2006   Phase 4   NCT00323297   Australia;Belgium;Czech Republic;Czechia;France;Germany;Greece;Israel;Italy;Taiwan;United Kingdom;United States
      2004   Phase 3   NCT00159874   Brazil;Canada;Chile;Colombia;Costa Rica;Guatemala;Hungary;India;Italy;Japan;Malaysia;Mexico;Panama;Poland;Russian Federation;Singapore;Sweden;Taiwan;United States
      2003   Phase 3   NCT00159861   Belgium;Canada;Czech Republic;Czechia;Denmark;France;Israel;Italy;Netherlands;Spain;United Kingdom;United States
      2002   Phase 3   NCT00159887   Australia;Belgium;Brazil;Czech Republic;Czechia;Denmark;France;Germany;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Singapore;South Africa;Spain;Sweden;United Kingdom;United States
   Pfizer, Inc.
      -   Phase 3   EUCTR2016-003978-41-Outside-EU/EEA   Japan
   Pfizer, Ltd.
      -   -   EUCTR2015-002238-37-Outside-EU/EEA   India
   Shanghai Pulmonary Hospital
      2009   -   ChiCTR-TCC-12002776   China
Sildenafil filmtabletten
   Pfizer Ltd.
      2009   -   EUCTR2008-003572-21-DE   Belgium;Germany;Spain;Sweden
Sildenafil singly or IN association with bosentan
   University of Sao Paulo General Hospital
      2011   -   NCT01548950   Brazil
Sildenafilo
   Pfizer, S.A.
      2009   Phase 2   EUCTR2008-003572-21-ES   Belgium;Germany;Spain;Sweden
Simvastatin
   University of Pennsylvania
      2006   Phase 2   NCT00384865   United States
Simvastatin 40 MG tablets
   Dept. of Internal Medicine II, University Hospital Giessen
      2006   -   EUCTR2005-004863-41-DE   Germany
Sirolimus
   Aadi Bioscience, Inc.
      2017   Phase 1   NCT02587325   United States
Sitaxentan
   Pfizer
      2011   Phase 1   NCT01251848   -
      2010   Phase 1   NCT01244620   Singapore
      2010   Phase 3   NCT01210443   Japan
      2010   Phase 3   NCT01204853   Japan
Sitaxentan sodium
   Pfizer
      2010   -   NCT00995566   Belgium;France;Germany;Sweden
      2009   -   NCT01445873   -
   Pfizer Japan Inc.
      2010   Phase 3   JPRN-jRCT2080221333   -
      2010   Phase 3   JPRN-jRCT2080221332   -
Sitaxsentan
   Pfizer
      2011   Phase 1   NCT01251848   -
      2010   Phase 1   NCT01244620   Singapore
      2008   Phase 3   NCT00795639   Argentina;Bulgaria;Chile;China;Colombia;Costa Rica;Czech Republic;Dominican Republic;Egypt;Guatemala;India;Jordan;Lebanon;Malaysia;Mexico;Peru;Philippines;Romania;Russian Federation;Saudi Arabia;Serbia;Slovakia;South Africa;Thailand;Turkey;Ukraine;United Arab Emirates;United States
      2003   Phase 3   NCT00811018   Argentina;Australia;Austria;Belgium;Brazil;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Poland;Spain;United Kingdom;United States
   University of Edinburgh
      2009   Phase 0   NCT01100736   United Kingdom
   West Penn Allegheny Health System
      2005   -   NCT00593905   United States
Sitaxsentan alone
   Pfizer
      2010   Phase 1   NCT01251835   -
Sitaxsentan and sildenafil
   Pfizer
      2010   Phase 3   NCT00796510   Argentina;Bulgaria;Chile;China;Colombia;Costa Rica;Czech Republic;Dominican Republic;India;Mexico;Peru;Philippines;Romania;Russian Federation;Saudi Arabia;Serbia;Slovakia;South Africa;Thailand;Ukraine;United States
      2009   Phase 3   NCT00796666   Argentina;Bulgaria;Chile;China;Colombia;Costa Rica;Czech Republic;Dominican Republic;India;Malaysia;Mexico;Peru;Philippines;Romania;Russian Federation;Saudi Arabia;Serbia;Slovakia;South Africa;Thailand;Turkey;Ukraine;United States
Sitaxsentan sodium
   Encysive Pharmaceuticals
      2003   Phase 3   NCT00080457   United States
   ICOS-Texas Biotechnology
      2002   Phase 2/Phase 3   NCT00034307   Canada;United States
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2009   -   EUCTR2008-005886-78-BG   Bulgaria;Czech Republic
      2009   -   EUCTR2008-005885-30-BG   Bulgaria;Czech Republic
   Pfizer Limited
      2009   Phase 3   EUCTR2008-005885-30-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent UK
      2009   Phase 3   EUCTR2008-005886-78-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2009   Phase 3   EUCTR2008-005887-14-SK   Bulgaria;Czech Republic;Slovakia
      2009   -   EUCTR2008-005887-14-BG   Bulgaria;Czech Republic
   Pfizer Ltd
      2010   -   EUCTR2008-005885-30-CZ   Bulgaria;Czech Republic
   Pfizer Ltd.
      2010   -   EUCTR2008-005887-14-CZ   Bulgaria;Czech Republic
      2010   Phase 3   EUCTR2008-005886-78-CZ   Bulgaria;Czech Republic
Slow dose titration group OF subcutaneous treprostinil
   United Therapeutics
      2017   Phase 4   NCT02893995   China
Sodium nitrite
   Aires Pharmaceuticals Inc
      2013   -   EUCTR2012-000166-37-PL   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000166-37-HU   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000166-37-DE   Australia;Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Poland;Romania;Serbia;United States
      2013   -   EUCTR2012-000166-37-CZ   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
   Aires Pharmaceuticals, Inc
      2013   -   EUCTR2012-000153-31-PL   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   Phase 2   EUCTR2012-000153-31-IT   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000153-31-HU   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
      2013   -   EUCTR2012-000153-31-DE   Australia;Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Poland;Romania;Serbia;United States
      2013   -   EUCTR2012-000153-31-CZ   Australia;Czech Republic;France;Germany;Hungary;Italy;Poland;Serbia;United States
Sodium nitrite inhalation solution
   Aires Pharmaceuticals, Inc.
      2012   Phase 2   NCT01725256   Australia;Hungary;United States
      2008   Phase 1   NCT00814645   United States
Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20MG sildenafil citrate BY mouth
   The First Affiliated Hospital of Guangzhou Medical University
      2013   Phase 2/Phase 3   NCT01637675   China
Sorafenib
   Medical Education Center, School of Medicine, Keio University
      2009   -   JPRN-UMIN000001709   Japan
   University of Chicago
      2007   Phase 1   NCT00452218   United States
Sotatercept
   ACCELERON PHARMA INC.
      2022   Phase 3   EUCTR2021-001498-21-IT   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2021-000199-12-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
   Acceleron Pharma Inc.
      2022   Phase 2   EUCTR2021-003020-32-ES   Belgium;Canada;France;Germany;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2022   Phase 3   EUCTR2021-000199-12-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 2   EUCTR2021-003020-32-FR   Belgium;Canada;France;Germany;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-FR   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-ES   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-FR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-ES   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czechia;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-FR   Argentina;Australia;Austria;Belgium;Brazil;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-ES   Argentina;Australia;Austria;Belgium;Brazil;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2021   Phase 3   EUCTR2020-004142-11-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;France;Germany;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 2   EUCTR2017-004738-27-BE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-GB   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-ES   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2017-004738-27-DE   Australia;Belgium;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
   Acceleron Pharma Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary of Merck & Co., Inc.)
      2018   Phase 2   NCT03496207   Australia;Brazil;France;Germany;Israel;Spain;United Kingdom;United States
   Acceleron Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2021-001498-21-DE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;South Africa;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
      2022   Phase 3   NCT04811092   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   NCT04896008   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   NCT04796337   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   NCT04576988   Argentina;Australia;Belgium;Brazil;Canada;Czechia;France;Germany;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Serbia;Spain;Sweden;Switzerland;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-NL   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-001498-21-BE   Australia;Belgium;Canada;France;Germany;Israel;Italy;Mexico;Netherlands;Spain;United Kingdom;United States
      2021   Phase 3   EUCTR2021-000199-12-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron, Pharma Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2021   Phase 3   EUCTR2021-000199-12-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Amsterdam UMC, location VUmc
      2025   Phase 4   NCT06658522   -
   Mayo Clinic
      2024   Phase 4   NCT06409026   United States
   Merck Sharp & Dohme LLC
      2025   Phase 2   NCT06925750   Colombia;United Kingdom
      2024   Phase 2   NCT06664801   Argentina;Australia;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Singapore;Spain;Taiwan;Thailand;United Kingdom;United States
      2023   Phase 3   NCT05818137   Japan
      2023   Phase 2   NCT05587712   Australia;Colombia;France;Germany;Israel;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2022-000478-25-NL   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2022-000478-25-FR   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2022-000478-25-DE   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 2   EUCTR2022-000478-25-PL   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 2   EUCTR2022-000478-25-ES   Australia;Colombia;France;Germany;Israel;Mexico;Netherlands;Poland;South Africa;Spain;Turkey;United Kingdom;United States
   Tanaka Yoshiyuki
      2023   Phase 3   JPRN-jRCT2031230046   -
Sotatercept - 45 MG/vial
   ACCELERON PHARMA INC.
      2022   Phase 3   EUCTR2020-005061-13-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma Inc.
      2022   Phase 3   EUCTR2020-005061-13-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      -   Phase 3   EUCTR2020-005061-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
Sotatercept - 60 MG/vial
   ACCELERON PHARMA INC.
      2022   Phase 3   EUCTR2020-005061-13-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma Inc.
      2022   Phase 3   EUCTR2020-005061-13-HR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      -   Phase 3   EUCTR2020-005061-13-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
   Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA
      2022   Phase 3   EUCTR2020-005061-13-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2022   Phase 3   EUCTR2020-005061-13-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
      2021   Phase 3   EUCTR2020-005061-13-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czech Republic;Czechia;Denmark;France;Germany;Greece;Ireland;Israel;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Serbia;Spain;Sweden;Switzerland;Taiwan;United Kingdom;United States
Spironolactone
   Baylor College of Medicine
      2011   Phase 4   NCT01468571   United States
   Hebei Medical University
      2005   Phase 1   NCT00240656   China
   National Institutes of Health Clinical Center (CC)
      2014   Phase 2   NCT01712620   United States
   Ottawa Heart Institute Research Corporation
      2018   Phase 4   NCT03344159   Canada
Spironolactone and conivaptan
   University of Colorado, Denver
      2009   -   NCT00811486   United States
Standard OF care - double oral
   AOP Orphan Pharmaceuticals AG
      2023   Phase 4   NCT06317805   Austria;Czechia;France;Germany;Hungary;Italy;Poland;Portugal;Romania;Spain
Standard-OF-care
   Actelion
      2017   Phase 3   NCT02932410   Argentina;Australia;Austria;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Hungary;Israel;Korea, Republic of;Malaysia;Mexico;Philippines;Poland;Portugal;Russian Federation;South Africa;Spain;Thailand;Ukraine;United States;Vietnam
Standardized meals
   United Therapeutics
      2009   Phase 1   NCT00963001   United States
STI571
   Novartis Pharma Services AG
      2006   -   EUCTR2005-005569-12-GB   Austria;Germany;United Kingdom
      2006   -   EUCTR2005-005569-12-DE   Austria;Germany;United Kingdom
      2006   -   EUCTR2005-005569-12-AT   Austria;Germany;United Kingdom
Subacute hypoxic exposures
   University of Oxford
      2013   -   NCT01847352   United Kingdom
Subcutaneous and intravenous prostacyclin
   United Therapeutics
      2010   -   NCT01266265   United States
Subcutaneous treprostinil
   Guangzhou Institute of Respiratory Disease
      2015   Phase 4   NCT06605326   -
   United Therapeutics
      2017   Phase 4   NCT02882126   China
Sugar pill
   Laval University
      2009   -   NCT01391104   Canada
   University of South Florida
      2012   -   NCT01645826   United States
Sulfasalazine
   RenJi Hospital
      2020   Phase 1/Phase 2   NCT04528056   China
Supplemental oxygen therapy
   University of Zurich
      2023   -   NCT06084559   Switzerland
Tadalafil
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2014-004786-25-IT   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   ACTELION Pharmaceuticals France
      2015   Phase 4   EUCTR2015-002078-19-FR   France
   Actelion
      2016   Phase 3   NCT02558231   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2015   Phase 4   NCT02968901   France
   Actelion Pharmaceuticals Ltd
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-ES   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-NO   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-FR   Australia;Austria;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2019   Phase 3   EUCTR2014-004786-25-PL   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Türkiye;United States
      2019   Phase 3   EUCTR2014-004786-25-ES   Australia;Brazil;Bulgaria;Canada;China;Czech Republic;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-DE   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
      2019   Phase 3   EUCTR2014-004786-25-BG   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   Bayer
      2017   Phase 4   NCT02891850   Australia;Austria;Belgium;Brazil;Canada;Czechia;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2019   Phase 4   EUCTR2016-001067-36-PL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-NL   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-GR   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DK   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-DE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-CZ   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2017   Phase 4   EUCTR2016-001067-36-BE   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-PT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-GB   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-ES   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Poland;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2016   Phase 4   EUCTR2016-001067-36-AT   Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Greece;Italy;Japan;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   ELI LILLY
      2006   -   EUCTR2005-002844-24-IT   Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002692-33-IT   Germany;Ireland;Italy;Spain;United Kingdom
   Eli Lilly Japan K.K.
      2017   Phase 3   JPRN-jRCT2080222307   Asia except Japan;Europe;Japan;North America;South America
   Eli Lilly and Company
      2014   Phase 3   NCT01824290   Austria;Belgium;Brazil;Canada;France;Germany;Israel;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;Turkey;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-GB   Canada;France;Poland;Spain;United Kingdom;United States
      2012   Phase 1;Phase 2   EUCTR2011-001873-24-ES   Canada;France;Poland;Spain;United Kingdom;United States
      2010   -   NCT01066845   -
      2006   -   EUCTR2005-002844-24-DE   Germany;Ireland;Italy;Spain;United Kingdom
      2005   Phase 3   NCT00549302   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Spain;United Kingdom;United States
      2005   Phase 3   NCT00125918   Belgium;Canada;France;Germany;Ireland;Italy;Japan;Spain;United Kingdom;United States
      -   Phase 1;Phase 2   EUCTR2011-001873-24-PL   Canada;France;Poland;Spain;United Kingdom;United States
   Eli Lilly and Company Limited
      2006   Phase 3;Phase 4   EUCTR2005-002844-24-BE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
   Gilead Sciences
      2008   Phase 4   NCT00617305   United States
   GlaxoSmithKline
      2010   Phase 3   NCT01178073   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-SE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   Phase 4   EUCTR2009-011150-17-NL   Austria;Belgium;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-IT   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-DE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-BE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-AT   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline,S.A.
      2010   -   EUCTR2009-011150-17-ES   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
   Hamamatsu University School of Medicine
      2011   -   JPRN-UMIN000005464   Japan
   Lilly ICOS LLC
      2006   -   EUCTR2005-002844-24-IE   Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002844-24-GB   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002844-24-ES   Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-IE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-GB   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-002692-33-ES   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002692-33-DE   Germany;Ireland;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002692-33-BE   Belgium;Germany;Ireland;Italy;Spain;United Kingdom
   National Cerebral and Cardiovascular Center
      2011   -   JPRN-UMIN000005973   Japan
   Pfizer
      2010   Phase 1   NCT01244620   Singapore
   Rabin Medical Center
      2008   Phase 4   NCT00705588   Israel
   Rhode Island Hospital
      2011   Phase 4   NCT01302444   United States
   Stanford University
      2010   Phase 4   NCT01305252   United States
   VU University Medical Center
      2013   Phase 4   NCT03236818   Netherlands
   Vigonvita Life Sciences
      2020   Phase 2   NCT04483115   China
Tadalafil 20 MG FILM-coated tablets
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-GR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   Phase 4   EUCTR2009-011150-17-GB   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
   GlaxoSmithKline Research & Development Limited
      2010   Phase 4   EUCTR2009-011150-17-FR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
Tadalafil 40 MG
   Actelion
      2019   Phase 3   NCT03904693   Australia;Brazil;Bulgaria;Canada;China;Czechia;Germany;Hungary;Italy;Japan;Malaysia;Mexico;Poland;Russian Federation;South Africa;Spain;Taiwan;Turkey;United States
   Janssen Pharmaceutical K.K.
      2020   Phase 3   JPRN-jRCT2080224886   Europe;Japan;South America
Tadalafil and ambrisentan upfront combination therapy
   Johns Hopkins University
      2010   Phase 4   NCT01042158   United States
Tadalafil mimic
   Second Affiliated Hospital, School of Medicine, Zhejiang University
      2025   -   NCT06968962   -
Tadalafil oral suspension
   Eli Lilly and Company
      2013   -   EUCTR2012-002354-23-RO   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-NL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-IT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-FR   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-DE   Austria;Belgium;Brazil;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Romania;Spain;Turkey;United Kingdom
      2013   Phase 3   EUCTR2012-002354-23-BE   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002354-23-AT   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-PL   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
      -   Phase 3   EUCTR2012-002354-23-GB   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
   Lilly S.A.
      2013   Phase 3   EUCTR2012-002354-23-ES   Austria;Belgium;Brazil;Canada;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Romania;Spain;Switzerland;United Kingdom;United States
Tadalafil- tablet or oral suspension
   Eli Lilly and Company
      2012   Phase 1/Phase 2   NCT01484431   Canada;France;Poland;Spain;United Kingdom;United States
Tadalafilo
   GlaxoSmithKline,S.A.
      2010   -   EUCTR2009-011150-17-ES   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
Tamoxifen
   Vanderbilt University Medical Center
      2018   Phase 2   NCT03528902   United States
Tasigna
   NOVARTIS FARMA
      2010   -   EUCTR2010-019883-36-IT   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;United States
   Novartis Pharma AG
      2010   -   EUCTR2010-019883-36-HU   Germany;Hungary
Tasigna® 150 MG
   Novartis Pharma Services AG
      2011   -   EUCTR2010-019883-36-DE   Canada;Germany;Hungary;Italy;Korea, Republic of;Singapore;Switzerland;United States
TBD
   Novartis Pharma AG
      2018   Phase 2   EUCTR2016-001411-20-GB   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001412-38-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
      2017   Phase 2   EUCTR2016-001411-20-DE   Germany;Korea, Republic of;Taiwan;United Kingdom;United States
Tegaderm
   Imperial College London
      2011   Phase 2   NCT01393795   United Kingdom
Terguride 0,5MG tablet
   Ergonex Pharma GmbH
      2008   -   EUCTR2007-003975-38-NL   Austria;Czech Republic;Germany;Netherlands
      2007   -   EUCTR2007-003975-38-DE   Austria;Czech Republic;Germany;Netherlands
Terguride 0.5 MG tablet
   Ergonex Pharma GmbH
      2010   -   EUCTR2007-003975-38-AT   Austria;Czech Republic;Germany;Netherlands
      2009   -   EUCTR2007-003975-38-CZ   Austria;Czech Republic;Germany;Netherlands
Tezosentan
   Actelion Pharmaceuticals Ltd.
      2009   Phase 2   EUCTR2009-012450-20-FR   France
   Idorsia Pharmaceuticals Ltd.
      2010   Phase 2   NCT01077297   France;Switzerland;United States
Thelin
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2009   -   EUCTR2008-005886-78-BG   Bulgaria;Czech Republic
      2009   -   EUCTR2008-005885-30-BG   Bulgaria;Czech Republic
   Pfizer Limited
      2009   Phase 3   EUCTR2008-005885-30-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent UK
      2009   Phase 3   EUCTR2008-005886-78-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2009   Phase 3   EUCTR2008-005887-14-SK   Bulgaria;Czech Republic;Slovakia
      2009   -   EUCTR2008-005887-14-BG   Bulgaria;Czech Republic
   Pfizer Ltd
      2010   -   EUCTR2008-005885-30-CZ   Bulgaria;Czech Republic
   Pfizer Ltd.
      2010   -   EUCTR2008-005887-14-CZ   Bulgaria;Czech Republic
      2010   Phase 3   EUCTR2008-005886-78-CZ   Bulgaria;Czech Republic
Threonine
   Medical Education Center, School of Medicine, Keio University
      2009   -   JPRN-UMIN000001709   Japan
Tocilizumab
   Papworth Hospital NHS Foundation Trust
      2016   Phase 2   NCT02676947   United Kingdom
      2015   Phase 2   EUCTR2015-002799-26-GB   United Kingdom
Tolvaptan
   Chinese Pulmonary Vascular Disease Research Group
      2021   -   NCT05569655   China
TPN171H
   Vigonvita Life Sciences
      2021   Phase 1   NCT05185011   China
      2020   Phase 2   NCT04483115   China
      2019   Phase 1   NCT05948644   China
TPN171H single dose
   Vigonvita Life Sciences
      2022   Phase 1   NCT05208814   China
Traclear
   Hanmi Pharmaceutical Company Limited
      2013   Phase 1   NCT01864863   Korea, Republic of
Tracleer
   ACTELION PHARMACEUTICALS ITALIA
      2005   -   EUCTR2004-005157-63-IT   Italy;United Kingdom
      2005   -   EUCTR2004-000745-37-IT   Italy;Spain;United Kingdom
   Actelion
      2004   Phase 4   NCT00367770   Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2013   Phase 3   EUCTR2010-021825-11-BG   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021825-11-NL   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021825-11-IT   Bulgaria;Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-NL   Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-IT   Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021793-12-HU   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-DE   Australia;Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2011   -   EUCTR2010-021793-12-CZ   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-HU   Bulgaria;Czech Republic;Germany;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021825-11-DE   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2010   -   EUCTR2010-021825-11-CZ   Australia;Belarus;Bulgaria;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      2009   -   EUCTR2005-005068-97-CZ   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2005-005068-97-BE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 4   EUCTR2005-005068-97-SK   Belgium;Brazil;Czech Republic;Denmark;Germany;Greece;Portugal;Saudi Arabia;Slovakia;Spain;Sweden;United Kingdom;United States
      2008   -   EUCTR2005-005068-97-PT   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   -   EUCTR2005-005068-97-GR   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 4   EUCTR2005-005068-97-ES   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Slovakia;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-SE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-GB   Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2005-005068-97-DK   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
      2006   -   EUCTR2004-004391-36-CZ   Czech Republic;Hungary
      2006   -   EUCTR2004-000745-37-GB   Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001967-70-GB   Germany;Italy;United Kingdom
      2005   -   EUCTR2004-004391-36-HU   Czech Republic;Hungary
      2005   Phase 3   EUCTR2004-000478-30-ES   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 4   EUCTR2004-000745-37-ES   Italy;Spain;United Kingdom
      2004   -   EUCTR2004-000478-30-SE   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   Phase 3   EUCTR2004-000478-30-GB   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-DK   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-CZ   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-BE   Austria;Belgium;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      2004   -   EUCTR2004-000478-30-AT   Austria;Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2010-021825-11-FR   Bulgaria;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Spain
      -   Phase 3   EUCTR2010-021793-12-PL   Belarus;China;Czech Republic;France;Germany;Hungary;India;Israel;Italy;Mexico;Netherlands;Poland;Russian Federation;Serbia;South Africa;Spain;Ukraine;United States
      -   Phase 3   EUCTR2010-021793-12-FR   Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
   Actelion pharmaceuticals Ltd
      2012   -   EUCTR2011-004612-31-PT   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      2012   -   EUCTR2011-004106-16-PT   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      2012   Phase 3   EUCTR2011-004106-16-BG   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004612-31-NL   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004612-31-FR   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004106-16-NL   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;South Africa;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2011-004106-16-FR   Argentina;Bulgaria;Chile;China;Colombia;Croatia;France;Guatemala;India;Malaysia;Mexico;Netherlands;Peru;Philippines;Portugal;Russian Federation;Serbia;Singapore;South Africa;Taiwan;Ukraine;United States;Vietnam
   ICIN
      2010   -   EUCTR2008-004533-21-NL   Netherlands
   NOVARTIS FARMA
      2011   -   EUCTR2010-021344-17-IT   Italy
   Rigshospitalet
      2006   -   EUCTR2006-000021-57-DK   Denmark
   Royal Brompton and Harefield NHS Trust
      2008   Phase 4   EUCTR2007-001643-21-GB   United Kingdom
      2007   -   EUCTR2007-001645-17-GB   United Kingdom
Tracleer tablet FOR oral suspension
   Humanis Saglik Anonim Sirketi
      2024   Phase 1   NCT06484673   Jordan
Tracleer*56CPR RIV 125MG
   Actelion Pharmaceuticals Ltd
      2004   -   EUCTR2004-000478-30-IT   Czech Republic;Denmark;Italy;Spain;Sweden;United Kingdom
Transdihydrolisuride
   Ergonex Pharma GmbH
      2010   -   EUCTR2007-003975-38-AT   Austria;Czech Republic;Germany;Netherlands
      2009   -   EUCTR2007-003975-38-CZ   Austria;Czech Republic;Germany;Netherlands
      2008   -   EUCTR2007-003975-38-NL   Austria;Czech Republic;Germany;Netherlands
      2007   -   EUCTR2007-003975-38-DE   Austria;Czech Republic;Germany;Netherlands
TRE
   United Therapeutics Corporation
      2005   -   EUCTR2004-003236-59-IT   Germany;Ireland;Italy;Spain;United Kingdom
Treprosinil diethanolamine
   United Therapeutics Corporation
      2007   Phase 3   EUCTR2006-000800-17-GB   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
Treprostin
   United Therapeutics Corporation
      2014   Phase 3   EUCTR2012-000097-26-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000097-26-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
Treprostinil
   Excelsior
      2025   -   NCT06603285   -
   Liquidia Technologies, Inc.
      2019   Phase 2   NCT03884465   France;Germany
   Los Angeles Biomedical Research Institute
      2010   Phase 4   NCT01268553   United States
   Magdi H. Yacoub
      2019   Phase 4   NCT03835676   Egypt
   Mayo Clinic
      2023   Phase 2   NCT05564637   United States
   Medtronic Cardiac Rhythm and Heart Failure
      2020   -   NCT03833323   -
   Mochida Pharmaceutical Co., Ltd.
      2019   Phase 2-3   JPRN-jRCT2080224582   Japan
   Rajan Saggar
      2008   Phase 2   NCT00705133   United States
   UNITED THERAPEUTICS
      2007   -   EUCTR2006-000801-50-IT   Austria;Belgium;France;Italy;Netherlands
   United Therapeutics
      2011   -   NCT01028651   United States
      2007   Phase 4   NCT00439946   United States
   United Therapeutics Corporation
      2007   -   EUCTR2006-000801-50-BE   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000800-17-BE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
Treprostinil dietanolamina
   United Therapeutics Corporation
      2009   Phase 3   EUCTR2009-009366-13-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
Treprostinil diethanolamine
   UNITED THERAPEUTICS
      2013   -   EUCTR2012-000098-21-IT   Australia;Austria;Brazil;Canada;Germany;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Taiwan;United Kingdom;United States
      2009   -   EUCTR2009-009366-13-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2006-000800-17-IT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
   United Therapeutics
      2013   Phase 3   NCT01934582   United States
      2012   Phase 3   NCT01560637   Argentina;Australia;Austria;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2010   Phase 1   NCT01172496   United States
      2010   Phase 1   NCT01165476   United States
      2010   Phase 1   NCT01153386   United States
      2010   Phase 1   NCT01131845   United States
      2009   Phase 1   NCT00963027   United States
      2009   Phase 1   NCT00963001   United States
      2006   Phase 3   NCT01027949   Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;India;Ireland;Israel;Italy;Mexico;Netherlands;Poland;Portugal;Puerto Rico;Spain;Sweden;United Kingdom;United States
   United Therapeutics Corporation
      2016   Phase 3   EUCTR2012-000098-21-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2016   Phase 3   EUCTR2012-000097-26-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2015   Phase 3   EUCTR2012-000098-21-FR   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000098-21-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000097-26-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000097-26-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2010   -   EUCTR2009-009366-13-PT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2006-000804-18-SE   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2006-000804-18-PT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-SE   Austria;Belgium;France;Germany;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2009-009366-13-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2006-000804-18-DE   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2008   -   EUCTR2006-000800-17-DE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-NL   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-IE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-GB   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-FR   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-BE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-AT   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000801-50-NL   Austria;Belgium;France;Italy;Netherlands
      2007   Phase 3   EUCTR2006-000801-50-FR   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000801-50-AT   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000800-17-NL   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   -   EUCTR2006-000800-17-IE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-GB   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-FR   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   -   EUCTR2006-000800-17-AT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      -   -   EUCTR2009-009366-13-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
Treprostinil diolamine
   United Therapeutics
      2012   Phase 3   NCT01560624   Argentina;Australia;Austria;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
Treprostinil inhalation powder
   Mannkind Corporation
      2018   Phase 1   NCT03464864   United States
   United Therapeutics
      2019   Phase 1   NCT03950739   United States
Treprostinil inhalations
   Stanford University
      2010   Phase 4   NCT01305252   United States
Treprostinil injectable product
   University of Arizona
      2019   Phase 3   NCT04062565   United States
Treprostinil palmitil
   F Ismat
      2022   Phase 2   JPRN-jRCT2071220033   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Phillipines;Spain;Switzerland;United Kingdom;United States
   Insmed Incorporated
      2023   Phase 2/Phase 3   NCT05649748   Argentina;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;United Kingdom;United States
      2022   Phase 2   NCT05147805   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   NCT04791514   United States
Treprostinil palmitil inhalation powder
   Fraz Ismat
      2023   Phase 2-3   JPRN-jRCT2061220089   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Phillipines;Spain;Switzerland;United Kingdom;United States
   INSMED INCORPORATED
      2023   Phase 2   EUCTR2022-001951-18-IT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-IT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;France;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
   Insmed Incorporated
      2023   Phase 2   EUCTR2022-001951-18-BE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-BE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
Treprostinil palmitil inhalation powder - 160 microgram
   Insmed Incorporated
      2023   Phase 2   EUCTR2022-001951-18-DE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2023   Phase 2   EUCTR2022-001951-18-AT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2022-001951-18-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
Treprostinil palmitil inhalation powder - 320 microgram
   Insmed Incorporated
      2023   Phase 2   EUCTR2022-001951-18-DE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2023   Phase 2   EUCTR2022-001951-18-AT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2022-001951-18-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
Treprostinil palmitil inhalation powder - 80 microgram
   Insmed Incorporated
      2023   Phase 2   EUCTR2022-001951-18-DE   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2023   Phase 2   EUCTR2022-001951-18-AT   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Peru;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2022-001951-18-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
      2022   Phase 2   EUCTR2021-001528-16-DK   Argentina;Australia;Austria;Belgium;Brazil;Denmark;Germany;Italy;Japan;Malaysia;Mexico;Philippines;Serbia;Spain;Switzerland;United Kingdom;United States
Treprostinil sodium
   AOP Orphan Pharmaceuticals AG
      2023   Phase 4   NCT06317805   Austria;Czechia;France;Germany;Hungary;Italy;Poland;Portugal;Romania;Spain
   AOP Orphan Pharmaceuticals GmbH
      2021   Phase 2   EUCTR2021-004002-21-AT   Austria
   Liquidia Technologies, Inc.
      2019   Phase 2   EUCTR2018-003414-40-FR   France;Germany
      2019   Phase 2   EUCTR2018-003414-40-DE   France;Germany
   United Therapeutics
      2008   Phase 4   NCT00643604   United States
      2007   Phase 4   NCT00458042   United States
      2006   Phase 4   NCT00373360   United States
      2005   Phase 4   NCT00494533   India
      2002   Phase 4   NCT00058929   United States
Treprostinil sodium solution FOR inhalation
   Lung Rx Inc.
      2005   -   EUCTR2004-003236-59-IE   Germany;Ireland;Italy;Spain;United Kingdom
   United Therapeutics Corporation
      2007   -   EUCTR2004-003236-59-ES   Germany;Ireland;Italy;Spain;United Kingdom
      2005   -   EUCTR2004-003236-59-IT   Germany;Ireland;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2004-003236-59-GB   Austria;Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2004-003236-59-BE   Austria;Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2005   -   EUCTR2004-003236-59-AT   Austria;Germany;Ireland;Italy;Spain;United Kingdom
      -   -   EUCTR2004-003236-59-DE   Germany;Ireland;Italy;Spain;United Kingdom
Treprostinil sodium, UT-15
   United Therapeutics Corp.
      2012   -   EUCTR2011-004631-31-DE   Germany
Treprostinil VIA implanted pump
   University Medicine Greifswald
      2020   -   NCT04309838   Germany
Treprostinil, UT-15, LRX-15, 15au81, BW A15AU, U-62, 840
   Lung Rx Inc.
      2005   -   EUCTR2004-003236-59-IE   Germany;Ireland;Italy;Spain;United Kingdom
   United Therapeutics Corporation
      2007   -   EUCTR2004-003236-59-ES   Germany;Ireland;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2004-003236-59-GB   Austria;Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2004-003236-59-BE   Austria;Belgium;Germany;Ireland;Italy;Spain;United Kingdom
      2005   -   EUCTR2004-003236-59-AT   Austria;Germany;Ireland;Italy;Spain;United Kingdom
      -   -   EUCTR2004-003236-59-DE   Germany;Ireland;Italy;Spain;United Kingdom
Trimetazidine
   Indonesia University
      2017   Phase 2/Phase 3   NCT03273387   Indonesia
Triple-combination therapy
   Guangdong Provincial People's Hospital
      2022   -   NCT06196801   China
TRK-100STP
   Lung LLC
      2010   -   EUCTR2009-014453-32-CZ   Belgium;Czech Republic;Germany;Ireland
      2010   Phase 2   EUCTR2009-014453-32-BE   Belgium;Czech Republic;Germany;Ireland;Romania;United States
      2009   -   EUCTR2008-006833-29-IE   Belgium;Ireland
      2009   Phase 2   EUCTR2008-006833-29-BE   Belgium;Ireland;United States
   Lung LLC Inc
      2010   -   EUCTR2009-014453-32-IE   Belgium;Czech Republic;Germany;Ireland
   Lung RX
      -   Phase 2   EUCTR2009-014453-32-DE   Belgium;Czech Republic;Germany;Ireland
   Lung Rx
      2009   -   EUCTR2008-003290-41-BE   Belgium;Ireland
   Lung Rx Inc
      2010   -   EUCTR2009-014246-29-CZ   Belgium;Czech Republic;Germany;Ireland
      2009   Phase 2   EUCTR2009-014246-29-BE   Belgium;Czech Republic;Germany;Ireland
   LungRx
      2009   -   EUCTR2008-003290-41-IE   Belgium;Ireland
Tyrosine
   Medical Education Center
      2008   -   JPRN-UMIN000001578   Japan
   Medical Education Center, School of Medicine, Keio University
      2009   -   JPRN-UMIN000001709   Japan
Tyvaso inhalation solution
   United Therapeutics
      2011   Phase 2   NCT01477333   United States
Ubenimex
   Eiger BioPharmaceuticals
      2016   Phase 2   NCT02736149   Canada;United States
      2016   Phase 2   NCT02664558   Canada;United States
Udenafil
   Dong-A ST Co., Ltd.
      2014   Phase 2/Phase 3   NCT02304198   Korea, Republic of
      2011   Phase 2   NCT01553721   Korea, Republic of
UK 092480
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2018   Phase 3;Phase 4   EUCTR2013-004362-34-LV   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-SE   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-PT   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Czechia;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   Phase 3;Phase 4   EUCTR2013-004362-34-NL   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2015   -   EUCTR2013-004362-34-HR   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   -   EUCTR2013-004362-34-RO   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-PL   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-GR   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 4   EUCTR2013-004362-34-ES   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-DE   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-CZ   Australia;Austria;Belgium;Bosnia and Herzegovina;Croatia;Czech Republic;Germany;Greece;Hong Kong;Israel;Latvia;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Thailand;Turkey;Ukraine;United States
      2014   Phase 3   EUCTR2013-004362-34-BE   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
      2014   Phase 3;Phase 4   EUCTR2013-004362-34-AT   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;Croatia;Czech Republic;Denmark;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Singapore;South Africa;Spain;Sweden;Taiwan;Thailand;Ukraine;United States
UK-92,480
   Pfizer
      2007   Phase 3   NCT00454207   Japan
   Pfizer Inc., 235 East 42nd Street, New York, NY 10017
      2009   -   EUCTR2008-005886-78-BG   Bulgaria;Czech Republic
   Pfizer Japan Inc
      -   -   EUCTR2014-004167-20-Outside-EU/EEA   Japan
   Pfizer Limited, Ramsgate Road, Sandwich, Kent UK
      2009   Phase 3   EUCTR2008-005886-78-SK   Bulgaria;Czech Republic;Slovakia
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      2009   Phase 3   EUCTR2008-005887-14-SK   Bulgaria;Czech Republic;Slovakia
      2009   -   EUCTR2008-005887-14-BG   Bulgaria;Czech Republic
      2007   Phase 3   EUCTR2005-000963-25-SK   Finland;Slovakia;Sweden;United Kingdom
      2007   -   EUCTR2005-000963-25-FI   Finland;Sweden;United Kingdom
      2006   Phase 3   EUCTR2005-000963-25-GB   Finland;Slovakia;Sweden;United Kingdom
      2005   -   EUCTR2005-000963-25-SE   Brazil;Chile;Colombia;Costa Rica;Finland;Guatemala;Hungary;India;Italy;Malaysia;Mexico;Poland;Russian Federation;Sweden;Taiwan;Thailand;United Kingdom
   Pfizer Ltd
      2006   Phase 4   EUCTR2006-001464-23-GB   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
      2007   Phase 3   EUCTR2006-002235-25-SK   Finland;Slovakia;United Kingdom
      2007   -   EUCTR2006-002235-25-FI   Finland;United Kingdom
      2006   Phase 3   EUCTR2006-002235-25-GB   Finland;Slovakia;United Kingdom
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent UK
      2008   -   EUCTR2006-006748-76-DK   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-BE   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer Ltd, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
      2009   -   EUCTR2006-006748-76-BG   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-LV   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   Phase 4   EUCTR2006-006748-76-GB   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2006   -   EUCTR2006-001464-23-DE   Australia;Belgium;Czech Republic;France;Germany;Greece;Israel;Italy;Taiwan;United Kingdom
   Pfizer Ltd,Ramsgate Road,Sandwich CT13 9NJ
      2008   -   EUCTR2006-001464-23-GR   Czech Republic;Germany;Greece;Italy;United Kingdom
      2006   -   EUCTR2006-001464-23-CZ   Czech Republic;Germany;Greece;Italy;United Kingdom
   Pfizer Ltd.
      2010   -   EUCTR2008-005887-14-CZ   Bulgaria;Czech Republic
      2010   Phase 3   EUCTR2008-005886-78-CZ   Bulgaria;Czech Republic
   Pfizer Ltd. Ramsgate Road, Sandwich, Kent, UK
      2008   -   EUCTR2006-006748-76-NL   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
      2008   -   EUCTR2006-006748-76-GR   Belgium;Bulgaria;Denmark;Greece;Italy;Latvia;Netherlands;United Kingdom
   Pfizer, Ltd.
      -   -   EUCTR2015-002238-37-Outside-EU/EEA   India
UK-92,480-10
   Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
      -   -   EUCTR2005-000963-25-Outside-EU/EEA   Brazil;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Russian Federation;Taiwan;United States
   Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
      -   -   EUCTR2006-002235-25-Outside-EU/EEA   Brazil;Canada;Chile;Colombia;Guatemala;India;Japan;Malaysia;Mexico;Peru;Russian Federation;Taiwan;United States
Ularitide
   Cardiorentis AG
      2021   Phase 2   EUCTR2020-004815-29-DE   Germany
Uptravi
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-002817-21-IT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 4   EUCTR2019-004783-22-NL   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-GB   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-FR   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Netherlands;Russian Federation;Saudi Arabia;United Arab Emirates;United Kingdom;United States
      2020   Phase 4   EUCTR2019-004783-22-DE   Argentina;Brazil;China;France;Germany;Hong Kong;Israel;Korea, Republic of;Malaysia;Netherlands;Russian Federation;Saudi Arabia;Singapore;United Arab Emirates;United Kingdom;United States
   Actelion
      2018   Phase 2   NCT03492177   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Malaysia;Poland;Romania;Russian Federation;Serbia;Taiwan;Ukraine;United Kingdom;United States
      2017   Phase 3   NCT03187678   Germany;United States
   Actelion Pharmaceuticals Ltd
      2018   Phase 2   EUCTR2018-000145-39-HU   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-GB   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-FR   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 2   EUCTR2018-000145-39-DE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      2018   Phase 4   EUCTR2017-000216-42-PT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 4   EUCTR2017-000216-42-FR   Austria;France;Germany;Ireland;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 3   EUCTR2015-003438-28-GB   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-SE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-IE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-GB   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-DE   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 4   EUCTR2017-000216-42-AT   Austria;France;Germany;Ireland;Netherlands;Norway;Portugal;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DK   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-DE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-BE   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2015-003438-28-AT   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Ireland;Italy;Netherlands;Norway;Spain;Sweden;Switzerland;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-PL   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-CZ   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2010   Phase 3   EUCTR2009-014992-31-AT   Argentina;Australia;Austria;Belarus;Belgium;Canada;Chile;China;Colombia;Czech Republic;Denmark;France;Germany;Greece;Hungary;India;Ireland;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Romania;Russian Federation;Serbia;Singapore;Slovakia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      -   Phase 2   EUCTR2018-000145-39-PL   Belarus;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
      -   Phase 2   EUCTR2018-000145-39-BE   Belarus;Belgium;Canada;China;France;Germany;Hungary;Israel;Italy;Malaysia;Netherlands;Poland;Romania;Russian Federation;Serbia;Singapore;Taiwan;Ukraine;United Kingdom;United States;Vietnam
   Actelion Pharmaceuticals Ltd.
      2021   Phase 3   EUCTR2019-002817-21-FI   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-PT   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-LT   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-HU   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-ES   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-DE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      2020   Phase 3   EUCTR2019-002817-21-BG   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2020   Phase 3   EUCTR2019-002817-21-BE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      2019   Phase 3   EUCTR2019-002817-21-PL   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-SE   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
      -   Phase 3   EUCTR2019-002817-21-IE   Australia;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Poland;Portugal;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Viet Nam
      -   Phase 3   EUCTR2019-002817-21-FR   Argentina;Australia;Austria;Belarus;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Denmark;Finland;France;Germany;Hungary;Ireland;Israel;Italy;Korea, Republic of;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Serbia;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United States;Vietnam
Uptravi® film coated tablets
   Humanis Saglik Anonim Sirketi
      2025   Phase 1   NCT06932198   Jordan
Urodilatin
   Cardiorentis AG
      2021   Phase 2   EUCTR2020-004815-29-DE   Germany
UT-15C
   United Therapeutics
      2012   Phase 3   NCT01560637   Argentina;Australia;Austria;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
UT-15C 0.25 MG
   United Therapeutics
      2008   Phase 3   NCT00760916   Australia;Mexico;United States
UT-15C 1 MG
   United Therapeutics
      2008   Phase 3   NCT00760916   Australia;Mexico;United States
UT-15C 5 MG
   United Therapeutics
      2008   Phase 3   NCT00760916   Australia;Mexico;United States
UT-15C LP
   United Therapeutics Corporation
      2007   -   EUCTR2006-000804-18-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
UT-15C SR
   UNITED THERAPEUTICS
      2013   -   EUCTR2012-000098-21-IT   Australia;Austria;Brazil;Canada;Germany;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Taiwan;United Kingdom;United States
      2009   -   EUCTR2009-009366-13-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-IT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   -   EUCTR2006-000801-50-IT   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000800-17-IT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
   United Therapeutics
      2013   Phase 3   NCT01934582   United States
      2012   Phase 2   NCT01588405   United States
      2011   Phase 2   NCT01477333   United States
      2010   Phase 1   NCT01131845   United States
      2009   Phase 3   NCT00887978   Belgium;Canada;France;Germany;Ireland;Israel;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States
   United Therapeutics Corporation
      2016   Phase 3   EUCTR2012-000098-21-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2016   Phase 3   EUCTR2012-000097-26-PL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2015   Phase 3   EUCTR2012-000098-21-FR   Australia;Austria;Belgium;Brazil;Canada;Denmark;France;Germany;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000098-21-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-SE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-GR   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2014   Phase 3   EUCTR2012-000097-26-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Peru;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000098-21-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000097-26-NL   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2013   Phase 3   EUCTR2012-000097-26-IT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000098-21-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-DE   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2012   Phase 3   EUCTR2012-000097-26-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;Chile;China;Denmark;France;Germany;Greece;India;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Singapore;Sweden;Taiwan;United Kingdom;United States
      2010   -   EUCTR2009-009366-13-PT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2006-000804-18-SE   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2010   Phase 3   EUCTR2006-000804-18-PT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-SE   Austria;Belgium;France;Germany;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2009-009366-13-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   Phase 3   EUCTR2009-009366-13-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2009   -   EUCTR2009-009366-13-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2008   Phase 3   EUCTR2006-000804-18-DE   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2008   -   EUCTR2006-000800-17-DE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-NL   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-IE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-GB   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-FR   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-BE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000804-18-AT   Austria;Belgium;France;Germany;Ireland;Israel;Italy;Mexico;Netherlands;Portugal;Puerto Rico;Spain;Sweden;United Kingdom
      2007   Phase 3   EUCTR2006-000801-50-NL   Austria;Belgium;France;Italy;Netherlands
      2007   Phase 3   EUCTR2006-000801-50-FR   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000801-50-BE   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000801-50-AT   Austria;Belgium;France;Italy;Netherlands
      2007   -   EUCTR2006-000800-17-NL   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   -   EUCTR2006-000800-17-IE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-GB   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-FR   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   Phase 3   EUCTR2006-000800-17-ES   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   -   EUCTR2006-000800-17-BE   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      2007   -   EUCTR2006-000800-17-AT   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
      -   -   EUCTR2009-009366-13-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Sweden;United Kingdom
UT-15C-SR
   United Therapeutics Corporation
      2007   Phase 3   EUCTR2006-000800-17-GB   Austria;Belgium;France;Germany;Ireland;Italy;Netherlands;Spain;United Kingdom
Valsartan 40 MG
   University of Washington
      2024   Phase 2   NCT06053580   United States
Vardenafil
   Rabin Medical Center
      2008   Phase 4   NCT00705588   Israel
   Tongji University
      2008   Phase 3   NCT00718952   China
Vasomera (PB1046) injection
   PhaseBio Pharmaceuticals, Inc.
      2021   Phase 2   EUCTR2019-001598-10-AT   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-PL   Austria;Belgium;Bulgaria;Czechia;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-HU   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-GR   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-ES   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
      2020   Phase 2   EUCTR2019-001598-10-BG   Austria;Belgium;Bulgaria;Czech Republic;Germany;Greece;Hungary;Italy;Poland;Romania;Serbia;Spain;United States
Ventavis
   Actelion
      2009   -   NCT00902603   United States
      2006   Phase 2   NCT00453414   United States
   Actelion Pharmaceuticals Ltd
      2009   -   EUCTR2009-010703-80-DE   Austria;Germany
      2009   -   EUCTR2009-010703-80-AT   Austria;Germany
   Actelion Pharmaceuticals Ltd.
      2009   -   EUCTR2009-011013-24-AT   Austria
   Actelion Pharmaceuticals US, Inc.
      2006   -   EUCTR2005-006192-13-GB   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   -   EUCTR2005-006192-13-DE   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   -   EUCTR2005-006192-13-AT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   Bayer
      2018   -   NCT03293407   Germany
      2016   -   NCT02826252   Germany
      2016   -   NCT02825160   Japan
      2014   Phase 1/Phase 2   NCT02032836   Austria;Germany
      2013   -   NCT01894035   Portugal
      2013   -   NCT01781052   France
      2012   Phase 3   NCT01469169   Japan
      2011   -   NCT01468545   Spain
      2010   -   NCT01355380   Poland
      2006   -   NCT01062282   Korea, Republic of
   COTHERIX, INC.
      2006   Phase 3   EUCTR2005-006192-13-IT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   CoTherix, Inc
      2007   -   EUCTR2005-006192-13-PT   Austria;Germany;Italy;Portugal;Spain;United Kingdom
      2006   Phase 3   EUCTR2005-006192-13-ES   Austria;Germany;Italy;Portugal;Spain;United Kingdom
   Royal Brompton and Harefield NHS Foundation Trust
      2014   Phase 4   EUCTR2014-000091-25-GB   United Kingdom
   Univ.Clinic of Internal Medicine II, Department of Cardiology, Medical University of Vienna, Austria
      2008   -   EUCTR2007-002803-42-AT   Austria
Ventavis 10
   Bayer AG
      2013   Phase 1;Phase 2   EUCTR2013-002783-12-AT   Austria;Germany
   Bayer HealthCare AG
      2014   Phase 1;Phase 2   EUCTR2013-002783-12-DE   Austria;Germany
Vericiguat
   Finn Gustafsson
      2024   Phase 4   NCT06671990   -
Viagra
   Actelion Pharmaceuticals Ltd.
      2006   Phase 2   EUCTR2005-005066-37-GB   Belgium;Germany;Italy;United Kingdom
      2006   -   EUCTR2005-005066-37-BE   Belgium;Germany;Italy;United Kingdom
      -   -   EUCTR2005-005068-97-DE   Belgium;Czech Republic;Denmark;Germany;Greece;Portugal;Spain;Sweden;United Kingdom
   Rigshospitalet
      2006   -   EUCTR2006-000021-57-DK   Denmark
VIP
   MONDOGEN AG
      2008   -   EUCTR2007-003621-24-IT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
   MondoGEN AG
      2009   -   EUCTR2007-003621-24-AT   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-NL   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   Phase 2   EUCTR2007-003621-24-GB   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   Phase 2   EUCTR2007-003621-24-FR   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-ES   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-DE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
      2008   -   EUCTR2007-003621-24-BE   Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
Volibris
   GlaxoSmithKline R&D Ltd
      2010   -   EUCTR2009-011150-17-SE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   Phase 4   EUCTR2009-011150-17-NL   Austria;Belgium;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-IT   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-GR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   Phase 4   EUCTR2009-011150-17-GB   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      2010   -   EUCTR2009-011150-17-DE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-BE   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2010   -   EUCTR2009-011150-17-AT   Australia;Austria;Belgium;Canada;France;Germany;Greece;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
   GlaxoSmithKline Research & Development Limited
      2010   Phase 4   EUCTR2009-011150-17-FR   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
      -   Phase 2   EUCTR2010-021572-29-FR   France;Germany;Greece;Hungary;Italy;Japan;Netherlands;Spain;United States
   GlaxoSmithKline Research & Development, Ltd
      2011   -   EUCTR2010-021572-29-NL   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-IT   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   -   EUCTR2010-021572-29-HU   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2011   Phase 3   EUCTR2010-021572-29-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-021572-29-GR   Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-NL   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-IT   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-HU   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   -   EUCTR2010-019547-19-GR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-FR   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
      2010   Phase 2   EUCTR2010-019547-19-DE   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline Research and Development Ltd
      2019   Phase 1   EUCTR2019-001699-12-GB   United Kingdom
   Thoraxklinik-Heidelberg gGmbH
      2014   Phase 2   EUCTR2014-001882-28-DE   Germany
Volibris 10 MG comprimidos recubiertos CON PELícula
   GlaxoSmithKline, S.A
      2011   Phase 3   EUCTR2010-021572-29-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline, S.A.
      2010   Phase 2   EUCTR2010-019547-19-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
Volibris 5 MG comprimidos recubiertos CON PELícula
   GlaxoSmithKline, S.A
      2011   Phase 3   EUCTR2010-021572-29-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline, S.A.
      2010   Phase 2   EUCTR2010-019547-19-ES   France;Germany;Greece;Hungary;Italy;Netherlands;Spain
   GlaxoSmithKline,S.A.
      2010   -   EUCTR2009-011150-17-ES   Austria;Belgium;France;Germany;Greece;Italy;Netherlands;Spain;Sweden;United Kingdom
Volibris™ tablets
   GlaxoSmithKline Research & Development Limited
      -   -   EUCTR2010-019547-19-Outside-EU/EEA   Argentina;Brazil;Canada;Japan;Mexico;Russian Federation;United States
Warfarin
   Bial - Portela C S.A.
      2018   Phase 1   NCT04994119   Germany
Zamicastat
   BIAL-Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-IT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-IT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela & Ca, S.A
      2019   Phase 2   EUCTR2018-002796-18-GB   Austria;Belgium;Germany;Netherlands;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-GB   Austria;Germany;Netherlands;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela & Ca, S.A.
      2019   Phase 2   EUCTR2018-002796-18-PT   Austria;Belgium;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002796-18-ES   Austria;Portugal;Spain;Ukraine;United Kingdom
      2019   Phase 2   EUCTR2018-002448-10-DE   Austria;Belgium;France;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002796-18-AT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002448-10-PT   Austria;Belgium;France;Germany;Italy;Netherlands;Portugal;Spain;Ukraine;United Kingdom
      2018   Phase 2   EUCTR2018-002448-10-ES   Austria;Portugal;Spain;Ukraine
      2018   Phase 2   EUCTR2018-002448-10-AT   Austria;Germany;Italy;Portugal;Spain;Ukraine;United Kingdom
   Bial - Portela C S.A.
      2019   Phase 2   NCT04316143   Spain