88. 慢性血栓塞栓性肺高血圧症 Disease details / Clinical trials / Drug dev / DR info

11C-acetate
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
6-minute walk distance (6MWD) test
   University of Zurich
      2023   -   NCT06003244   Switzerland
6-minute walk distance (6MWD) test ON ambient AIR
   University of Zurich
      2024   -   NCT06384534   Switzerland
6-minute walk distance test with supplemental oxygen
   University of Zurich
      2024   -   NCT06384534   Switzerland
ACT-064992
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
   Actelion Pharmaceuticals Ltd.
      2015   Phase 2   EUCTR2013-003457-25-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-003457-25-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-002950-56-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-003457-25-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-GB   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-FR   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-CZ   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-BE   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-AT   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-GB   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-CZ   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-BE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-AT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
ACT-293987
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2018-002823-41-IT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2019   Phase 3   EUCTR2018-002823-41-PT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-NL   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-HU   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-GB   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DK   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-CZ   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BG   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-AT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
Adempas
   Bayer
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2014   -   NCT02117791   Japan
      2013   -   NCT01784562   Austria;Belgium;Canada;Colombia;Czech Republic;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00910429   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00855465   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Chinese University of Hong Kong
      2024   Phase 4   NCT06715280   Hong Kong
   International CTEPH Association (ICA)
      2018   Phase 2   EUCTR2017-001121-40-GB   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-FR   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-DE   France;Germany;United Kingdom;United States
Ambrisentan
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001646-18-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001646-18-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001642-17-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   Phase 3   EUCTR2012-001642-17-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-001642-17-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline, S.A.
      2013   -   EUCTR2012-001646-18-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
Ambrisentan 5 MG
   GlaxoSmithKline
      2014   Phase 3   NCT01894022   Argentina;Austria;Canada;China;Czech Republic;Czechia;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States
      2013   Phase 3   NCT01884675   Argentina;Austria;Canada;China;Czech Republic;Germany;Israel;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;United Kingdom;United States
Ammonia
   Ottawa Heart Institute Research Corporation
      2014   Phase 2   NCT02094001   Canada
Atorvastatin
   Tongji Hospital of Tongji University
      2008   -   ChiCTR-TNRC-08000263   China
Ballon pulmonary angioplasty
   Medical University of Vienna
      2017   -   NCT03074539   Austria
Balloon pulmonary angioplasty
   Assistance Publique - Hôpitaux de Paris
      2016   -   NCT02634203   France
   Dr Sudarshan Rajagopal
      2025   Phase 3   NCT05140525   United States
   International CTEPH Association
      2023   -   NCT05629052   Argentina;Austria;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;Germany;India;Italy;Japan;Mexico;Poland;Singapore;Spain;Turkey;United Kingdom;United States
   Shimokawahara Hiroto
      2021   Phase 2   JPRN-jRCTs041200052   -
Barnascan
   IDIBAPS
      2016   Phase 2   EUCTR2016-000347-14-ES   Spain
BAY 63-2521
   Bayer HealthCare AG
      2008   Phase 3   EUCTR2007-000072-16-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
   International CTEPH Association (ICA)
      2018   Phase 2   EUCTR2017-001121-40-GB   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-FR   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-DE   France;Germany;United Kingdom;United States
   Thoraxklinik Heidelberg gGmbH
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
BAY 63-2521 coated tablets 0.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 1 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 1.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 2 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 coated tablets 2.5 MG
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 IR coated tablet 1.0 MG
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR coated tablet 1.5 MG
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR coated tablet 2.0 MG
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR coated tablet 2.5 MG
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR tablet 0.5 MG
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR tablet 1.0 MG
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-SE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR tablet 1.5 MG
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-SE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR tablet 2.0 MG
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-SE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 IR tablet 2.5 MG
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-SE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
BAY 63-2521 tablets 0.5 MG
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2007-000072-16-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 tablets 1 MG
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2007-000072-16-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 tablets 1.5 MG
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2007-000072-16-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
BAY 63-2521 tablets 2 MG
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
BAY 63-2521 tablets 2.5 MG
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
BAY1237592
   Bayer
      2019   Phase 1   NCT03754660   Austria;Czechia;Germany;Poland
BAY63-2521
   Bayer
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2014   -   NCT02117791   Japan
      2013   -   NCT01784562   Austria;Belgium;Canada;Colombia;Czech Republic;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00910429   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00855465   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Blood sample
   Centre Hospitalier Universitaire de Saint Etienne
      2022   -   NCT05340023   France
Bosentan
   ACTELION PHARMACEUTICALS ITALIA
      2006   -   EUCTR2005-002900-40-IT   Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-IT   Germany;Italy;Spain;United Kingdom
   Actelion
      2006   Phase 3   NCT00319111   Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States
      2005   Phase 3   NCT00313222   Australia;Austria;Belgium;Canada;Czech Republic;France;Germany;Italy;Netherlands;Poland;Spain;United Kingdom;United States
   Actelion Pharmaceuticals Ltd.
      2006   -   EUCTR2005-002900-40-DE   Czech Republic;Germany;Italy;Spain;United Kingdom
Bosentan monohydrate
   Actelion Pharmaceuticals Ltd.
      2006   Phase 3   EUCTR2005-002900-40-GB   Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-CZ   Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-BE   Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-002900-40-AT   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-GB   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-DE   Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-CZ   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-AT   Austria;Germany;Italy;Spain;United Kingdom
BPA
   Assistance Publique - Hôpitaux de Paris
      2016   -   NCT02634203   France
   Fukuda Keiichi
      2016   -   JPRN-jRCTs031180239   -
   Keio University School of Medicine
      2016   -   JPRN-UMIN000019549   Japan
   Shanghai Pulmonary Hospital
      2021   Phase 0   ChiCTR2000032403   China
   Shimokawahara Hiroto
      2021   Phase 2   JPRN-jRCTs041200052   -
Catheter directed therapy
   University of Arizona
      2022   -   NCT05133713   United States
Computed tomography lung subtraction iodine mapping
   University of Sheffield
      2019   -   NCT03806907   -
D-glucose
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
Dapagliflozin
   Mads Ersbøll
      2023   Phase 2   NCT05179356   Denmark
   Rigshospitalet The Heart Center
      2022   Phase 2   EUCTR2021-006787-25-DK   Denmark
Diltiazem
   Beijing Chao-Yang Hospital, Capital Medical University
      2025   -   ChiCTR2500102519   China
Edoxaban
   Abe Kohtaro
      2021   Phase 3   JPRN-jRCT2071200098   -
   Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
      2016   Phase 4   JPRN-UMIN000018520   Japan
   Kyushu University
      2021   Phase 3   NCT04730037   Japan
Endogenous thrombin potential
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
Fludeoxyglucose
   IDIBAPS
      2016   Phase 2   EUCTR2016-000347-14-ES   Spain
Forxiga
   Rigshospitalet The Heart Center
      2022   Phase 2   EUCTR2021-006787-25-DK   Denmark
GSK1325760
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001646-18-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001646-18-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001642-17-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   Phase 3   EUCTR2012-001642-17-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-001642-17-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline, S.A.
      2013   -   EUCTR2012-001646-18-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
Hyperpolarized XE129
   Bastiaan Driehuys
      2024   Phase 2   NCT06038630   United States
Imatinib mesilate
   Imperial College London
      2020   Phase 2   EUCTR2020-001157-48-GB   United Kingdom
JNJ-67896062 / ACT-064992
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
Light transmission aggregometry
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
Long term oxygen therapy
   University of Zurich
      2013   Phase 3   NCT01884012   Switzerland
Macitentan
   Actelion
      2020   Phase 3   NCT04271475   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2018   Phase 3   NCT03422328   Belarus;Belgium;France;Poland;Russian Federation;Turkey;Ukraine
      2015   Phase 2   NCT02060721   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   NCT02021292   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Italy;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Turkey;Ukraine;United Kingdom;United States;Vietnam
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
   Actelion Pharmaceuticals Ltd.
      2015   Phase 2   EUCTR2013-003457-25-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-003457-25-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-002950-56-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-003457-25-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-GB   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-FR   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-CZ   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-BE   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-AT   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-GB   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-CZ   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-BE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-AT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
Macitentan 10 MG
   Actelion
      2019   Phase 3   NCT03809650   Japan
   Nakano Masayoshi
      2021   Phase 3   JPRN-jRCT2051200150   Germany;Hungary;Japan;South Korea;USA
Macitentan 10MG
   Assistance Publique - Hôpitaux de Paris
      2021   Phase 2/Phase 3   NCT04780932   France
Macitentan compresse
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
Macitentan tablets
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
   Dr Sudarshan Rajagopal
      2025   Phase 3   NCT05140525   United States
Macitentan tablets
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 3   EUCTR2019-004131-24-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
Methyl 4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-B]pyridine-3-YL]-5-pyrimidinyl(methyl)carb
   Bayer AG
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2007-000072-16-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
Methyl [4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-B]pyridin-3-YL]-5-pyrimidinyl]meth
   Bayer HealthCare AG
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
MK-4836
   Thoraxklinik Heidelberg gGmbH
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
Multihance
   Brigham and Women's Hospital
      2013   Phase 2   NCT01953965   United States
N-acetyl cysteine
   Instituto Nacional de Cardiologia Ignacio Chavez
      2019   -   NCT04081012   Mexico
Nitric oxide
   Ogo Takeshi
      2022   Phase 2   JPRN-jRCT2051220042   -
   Sato Shuji
      2022   -   JPRN-jRCT1030220553   -
Opsumit
   ACTELION PHARMACEUTICALS LTD
      2020   Phase 3   EUCTR2019-004131-24-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
   ACTELION Pharmaceuticals Ltd.
      2022   Phase 3   EUCTR2019-004131-24-PT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2022   Phase 3   EUCTR2019-004131-24-DK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2021   Phase 3   EUCTR2019-004131-24-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-SK   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-PL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-LT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-HU   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
      2020   Phase 3   EUCTR2019-004131-24-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2021   Phase 3   EUCTR2017-003934-10-PL   Belarus;Belgium;France;Germany;Poland;Russian Federation;Turkey;Ukraine
   Actelion Pharmaceuticals Ltd.
      2015   Phase 2   EUCTR2013-003457-25-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-003457-25-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2015   Phase 2   EUCTR2013-002950-56-LT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-003457-25-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-GB   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-FR   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;Czechia;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-CZ   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-BE   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-003457-25-AT   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-NL   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-HU   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-GB   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-DE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-CZ   Austria;Belgium;Bulgaria;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Italy;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Sweden;Switzerland;Thailand;Ukraine;United Kingdom;United States
      2014   Phase 2   EUCTR2013-002950-56-BE   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
      2014   Phase 2   EUCTR2013-002950-56-AT   Austria;Belgium;Canada;Chile;China;Czech Republic;France;Germany;Hungary;Korea, Republic of;Lithuania;Mexico;Netherlands;Poland;Russian Federation;South Africa;Switzerland;Thailand;Ukraine;United Kingdom;United States;Vietnam
Opsumit®
   ACTELION Pharmaceuticals Ltd.
      2020   Phase 3   EUCTR2019-004131-24-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Japan;Korea, Republic of;Lithuania;Mexico;Poland;Portugal;Romania;Russian Federation;Saudi Arabia;Serbia;Singapore;Slovakia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States
Oxygen
   Heidelberg University
      2019   Phase 2   NCT04207593   Germany
   University of Zurich
      2023   -   NCT06003244   Switzerland
Oxygen administration
   Bastiaan Driehuys
      2024   Phase 2   NCT06038630   United States
   Department of Cardiology, Hospital Organization Okayama Medical Center
      2015   -   JPRN-UMIN000026882   Japan
Oxygen, liquid
   Thoraxklinik-Heidelberg gGmbH
      2019   Phase 2   EUCTR2018-001387-39-DE   Germany
Platelet function analyzer-100
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
Pulmonary endarterectomy
   International CTEPH Association
      2023   -   NCT05629052   Argentina;Austria;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;Germany;India;Italy;Japan;Mexico;Poland;Singapore;Spain;Turkey;United Kingdom;United States
      2018   Phase 2   NCT03273257   France;Germany;United Kingdom;United States
Pulmonary endarteriectomy
   Medical University of Vienna
      2017   -   NCT03074539   Austria
Pulmonary hypertension (PH)-specific medication
   International CTEPH Association
      2023   -   NCT05629052   Argentina;Austria;Belgium;Brazil;Canada;China;Colombia;Czech Republic;Denmark;Germany;India;Italy;Japan;Mexico;Poland;Singapore;Spain;Turkey;United Kingdom;United States
Remodulin 10MG/ML 20ML
   MRN-Medical Research Network GmbH
      2010   -   EUCTR2008-006441-10-DE   Austria;Czech Republic;Germany
Remodulin 1MG/ML 20ML
   MRN-Medical Research Network GmbH
      2010   -   EUCTR2008-006441-10-DE   Austria;Czech Republic;Germany
Remodulin 2.5MG/ML 20ML
   MRN-Medical Research Network GmbH
      2010   -   EUCTR2008-006441-10-DE   Austria;Czech Republic;Germany
Remodulin 5MG/ML 20ML
   MRN-Medical Research Network GmbH
      2010   -   EUCTR2008-006441-10-DE   Austria;Czech Republic;Germany
Respiratory and exercise therapy with supplemental oxygen
   University of Zurich
      2015   -   NCT02558582   Switzerland
Riociguat
   Adachi Shiro
      2021   -   JPRN-jRCT1041210122   -
   Assistance Publique - Hôpitaux de Paris
      2016   -   NCT02634203   France
   Bayer
      2015   -   NCT02545465   Belgium;Canada;Colombia;Denmark;Germany;Japan;Sweden;Turkey;United Kingdom
      2014   -   NCT02117791   Japan
      2013   -   NCT01784562   Austria;Belgium;Canada;Colombia;Czech Republic;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00910429   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   NCT00855465   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2009   Phase 3   EUCTR2008-003539-19-PT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer AG
      2013   Phase 3   EUCTR2012-002104-40-PT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-DE   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2010   Phase 3   EUCTR2008-003539-19-SK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Bayer HealthCare AG
      2013   Phase 3   EUCTR2012-002104-40-SE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-NL   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-IT   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-GB   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-ES   Austria;Belgium;Brazil;Canada;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-DK   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-CZ   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-002104-40-BE   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-002104-40-AT   Austria;Belgium;Brazil;Canada;Colombia;Czech Republic;Denmark;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States
      2010   Phase 3   EUCTR2008-003539-19-DK   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2010   -   EUCTR2007-000072-16-DK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-CZ   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-BE   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2008-003539-19-AT   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
      2009   Phase 3   EUCTR2007-000072-16-SK   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-PT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-IE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2007-000072-16-CZ   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-BE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   Phase 3   EUCTR2007-000072-16-AT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-IT   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2008   Phase 3   EUCTR2007-000072-16-ES   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2006   Phase 1;Phase 2   EUCTR2006-003520-10-DE   Germany
      -   -   EUCTR2007-000072-16-DE   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, Bayer Vital GmbH, D-51368 Leverkusen
      2009   Phase 3   EUCTR2008-003539-19-NL   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
      2009   -   EUCTR2008-003539-19-IE   Austria;Belgium;Czech Republic;France;Germany;Ireland;Italy;Netherlands;Portugal;Spain;United Kingdom
      2009   Phase 3   EUCTR2008-003539-19-FR   Austria;Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Portugal;Slovakia;Spain;United Kingdom
   Bayer HealthCare AG, D-51368 Leverkusen
      2009   Phase 3   EUCTR2007-000072-16-GB   Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Ireland;Israel;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Slovakia;Spain;Switzerland;Taiwan;Turkey;United Kingdom;United States
   Beijing Chao-Yang Hospital, Capital Medical University
      2025   -   ChiCTR2500102519   China
      2025   Phase 4   ChiCTR2500099401   China
   Chinese University of Hong Kong
      2024   Phase 4   NCT06715280   Hong Kong
   Dr Sudarshan Rajagopal
      2025   Phase 3   NCT05140525   United States
   Fukuda Keiichi
      2016   -   JPRN-jRCTs031180239   -
   Heidelberg University
      2022   Phase 4   NCT04954742   Germany
   International CTEPH Association
      2018   Phase 2   NCT03273257   France;Germany;United Kingdom;United States
   International CTEPH Association (ICA)
      2018   Phase 2   EUCTR2017-001121-40-GB   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-FR   France;Germany;United Kingdom;United States
      2018   Phase 2   EUCTR2017-001121-40-DE   France;Germany;United Kingdom;United States
   Keio University School of Medicine
      2016   -   JPRN-UMIN000019549   Japan
   Medical University of Vienna
      2017   -   NCT03074539   Austria
   Shanghai Pulmonary Hospital
      2021   Phase 0   ChiCTR2000032403   China
   Shimokawahara Hiroto
      2021   Phase 2   JPRN-jRCTs041200052   -
   Suqiao Yang
      2025   Phase 3   NCT06922240   China
   Thoraxklinik Heidelberg gGmbH
      2021   Phase 4   EUCTR2020-005462-34-DE   Germany
Riociguat oral tablet
   National Hospital Organization Okayama Medical Center
      2020   Phase 2   NCT04600492   Japan
RO 47-0203
   Actelion Pharmaceuticals Ltd.
      2006   Phase 3   EUCTR2005-002900-40-GB   Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-DE   Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-CZ   Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-BE   Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-002900-40-AT   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-GB   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-DE   Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-CZ   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-AT   Austria;Germany;Italy;Spain;United Kingdom
Rotational thromboelastometry
   National and Kapodistrian University of Athens
      2015   -   NCT03195543   Greece
Routine treatment
   Beijing Chao-Yang Hospital, Capital Medical University
      2025   Phase 4   ChiCTR2500099401   China
   Suqiao Yang
      2025   Phase 3   NCT06922240   China
Sauerstoff
   Thoraxklinik-Heidelberg gGmbH
      2019   Phase 2   EUCTR2018-001387-39-DE   Germany
Selexipag
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2018-002823-41-IT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion
      2019   Phase 3   NCT03689244   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czechia;Denmark;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2019   Phase 3   EUCTR2018-002823-41-PT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-NL   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-HU   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-GB   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DK   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-CZ   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BG   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-AT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Adachi Shiro
      2021   -   JPRN-jRCT1041210122   -
   NIPPON SHINYAKU CO., LTD.
      2013   Phase 2   JPRN-jRCT2080222113   -
   NIPPON SHINYAKU CO., LTD. / Actelion Pharmaceuticals Japan Ltd.
      2011   Phase 2   JPRN-jRCT2080221626   -
      2011   Phase 2   JPRN-jRCT2080221625   -
   Nippon Shinyaku Co., Ltd.
      2016   Phase 3   JPRN-jRCT2080223224   Japan
Sham oxygen therapy
   University of Zurich
      2023   -   NCT06084559   Switzerland
Supplemental oxygen therapy
   University of Zurich
      2023   -   NCT06084559   Switzerland
Supplemental oxygen VIA A mask
   University of Zurich
      2012   Phase 2   NCT01748474   Switzerland
Systemic anticoagulation
   University of Arizona
      2022   -   NCT05133713   United States
Tracleer
   ACTELION PHARMACEUTICALS ITALIA
      2005   -   EUCTR2005-001965-33-IT   Germany;Italy;Spain;United Kingdom
   Actelion Pharmaceuticals Ltd.
      2006   Phase 3   EUCTR2005-002900-40-GB   Austria;Belgium;Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-DE   Czech Republic;Germany;Italy;Spain;United Kingdom
      2006   -   EUCTR2005-002900-40-CZ   Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-002900-40-AT   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-GB   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-DE   Germany;Italy;Spain;United Kingdom
      2005   Phase 3   EUCTR2005-001965-33-CZ   Austria;Czech Republic;Germany;Italy;Spain;United Kingdom
      2005   -   EUCTR2005-001965-33-AT   Austria;Germany;Italy;Spain;United Kingdom
Tracleer*56CPR RIV 125MG
   ACTELION PHARMACEUTICALS ITALIA
      2006   -   EUCTR2005-002900-40-IT   Czech Republic;Germany;Italy;Spain;United Kingdom
Treprostinil sodium
   MRN-Medical Research Network GmbH
      2010   -   EUCTR2008-006441-10-DE   Austria;Czech Republic;Germany
   SCIPHARM SáRL
      2009   Phase 3   EUCTR2008-006441-10-CZ   Austria;Czech Republic;Germany;Poland;Slovakia
      2009   Phase 3   EUCTR2008-006441-10-AT   Austria;Czech Republic;Germany;Poland;Slovakia
   SciPharm SàRL
      2009   Phase 3   NCT01416636   Austria;Czech Republic;Czechia;Germany;Poland
Uptravi
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 3   EUCTR2018-002823-41-IT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Democratic People's Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
   Actelion Pharmaceuticals Ltd
      2019   Phase 3   EUCTR2018-002823-41-PT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-NL   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-HU   Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-GB   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DK   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-DE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-CZ   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Finland;Germany;Hungary;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BG   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-BE   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Czechia;Denmark;Finland;Germany;Hungary;India;Israel;Italy;Korea, Republic of;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002823-41-AT   Argentina;Australia;Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Estonia;Finland;Germany;Greece;Hong Kong;Hungary;Israel;Italy;Korea, Republic of;Latvia;Lithuania;Mexico;Netherlands;Poland;Portugal;Russian Federation;Singapore;Slovakia;South Africa;Spain;Sweden;Switzerland;Taiwan;Thailand;Turkey;Ukraine;United Kingdom;United States
Volibris
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001646-18-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001646-18-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom
      2013   -   EUCTR2012-001646-18-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline Research & Developement Ltd
      2014   Phase 3   EUCTR2012-001642-17-IT   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Israel;Italy;Japan;Korea, Democratic People's Republic of;Mexico;Netherlands;Russian Federation;Spain;Turkey;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-NL   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   Phase 3   EUCTR2012-001642-17-GB   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-DE   Argentina;Austria;Brazil;Canada;China;Czech Republic;Germany;Italy;Japan;Mexico;Netherlands;Russian Federation;Saudi Arabia;Spain;Turkey;United Kingdom;United States
      2013   Phase 3   EUCTR2012-001642-17-CZ   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
      2013   -   EUCTR2012-001642-17-AT   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;United Kingdom
   GlaxoSmithKline, S.A.
      2013   -   EUCTR2012-001646-18-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      2013   -   EUCTR2012-001642-17-ES   Argentina;Austria;Brazil;Canada;China;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
Warfarin
   Abe Kohtaro
      2021   Phase 3   JPRN-jRCT2071200098   -
   Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine
      2016   Phase 4   JPRN-UMIN000018520   Japan
Warfarin potassium
   Kyushu University
      2021   Phase 3   NCT04730037   Japan