Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetic acid C-11 1件: 11C-acetate---3件: 13, 86, 88 💬
2 Ambrisentan 1件: Ambrisentan1件: Ambrisentan 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 51, 66, 84, 85, 86, 88, 210, 211 💬
3 Ammonia 1件: Ammonia1件: Ammonia solution, strong 💬 --3件: 88, 251, 296 💬
4 Atorvastatin 2件: Atorvastatin; Atorvastatin calcium2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬20件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
5 Bisphenol A 0件: ---1件: 88 💬
6 Bosentan 2件: Bosentan; Bosentan monohydrate2件: Bosentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
7 D-glucose 1件: D-glucose---2件: 86, 88 💬
8 Dapagliflozin 1件: Dapagliflozin1件: Dapagliflozin 💬 --13件: 6, 19, 28, 49, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
9 Diltiazem 2件: Diltiazem; Diltiazem hydrochloride3件: Diltiazem hydrochloride ,
Diltiazem malate ,
Diltiazem 💬 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 58, 86, 88 💬
10 Edoxaban 1件: Edoxaban3件: Edoxaban tosilate hydrate ,
Edoxaban ,
Edoxaban tosylate 💬 		1件: F10 💬 1件: Complement and coagulation cascades 💬2件: 46, 88 💬
11 Fludeoxyglucose 1件: Fludeoxyglucose---2件: 34, 88 💬
12 Imatinib 2件: Imatinib; Imatinib mesylate2件: Imatinib mesylate ,
Imatinib 💬 		3件: ABL1,
KIT,
PDGFRA 💬 		31件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
13 Macitentan 1件: Macitentan1件: Macitentan 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 51, 85, 86, 88, 210 💬
14 Nitric Oxide 1件: Nitric oxide1件: Nitric oxide 💬 --9件: 51, 85, 86, 88, 97, 210, 251, 294, 299 💬
15 Oxygen 1件: Oxygen1件: Oxygen 💬 --18件: 6, 19, 22, 49, 70, 85, 86, 88, 96, 97, 149, 168, 211, 235, 271, 298, 299, 330 💬
16 Riociguat 1件: Riociguat1件: Riociguat 💬 3件: GUCY1A,
GUCY1A,
GUCY1B 💬 		10件: Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬6件: 51, 84, 86, 88, 225, 299 💬
17 Selexipag 1件: Selexipag1件: Selexipag 💬 1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 47, 51, 70, 84, 86, 88 💬
18 Treprostinil 3件: Treprostinil; Treprostinil diolamine; Treprostinil sodium3件: Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 85, 86, 88, 210 💬
19 Warfarin 3件: Warfarin; Warfarin potassium; Warfarin sodium3件: Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬12件: 6, 8, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬