94. 原発性硬化性胆管炎 Disease details / Clinical trials / Drug dev / DR info


臨床試験数 : 177 / 薬物数 : 120 - (DrugBank : 48) / 標的遺伝子数 : 25 - 標的パスウェイ数 : 148

薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
11C-csar
   University of Aarhus
      2013   Phase 1   NCT01879735   Denmark
45 GY external radiations
   Azienda Ospedaliera di Padova
      2012   -   NCT01549795   Italy
Acetylcysteine
   POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
      2012   -   EUCTR2012-004170-26-IT   Italy
Acido deossicolico
   DR. FALK PHARMA GMBH
      2018   Phase 3   EUCTR2016-003367-19-IT   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Sweden;Switzerland;United Kingdom
Acido obeticolico
   INTERCEPT PHARMACEUTICALS INC.
      2015   Phase 2   EUCTR2014-002205-38-IT   Italy;United States
Alanine
   Nakamoto Nobuhiro
      2024   Phase 2   JPRN-jRCTs031230676   -
Aldafermin
   NGM Biopharmaceuticals, Inc
      2024   Phase 2/Phase 3   NCT06654726   United States
ALL-trans retinoic acid
   Yale University
      2018   Phase 2   NCT03359174   United States
      2011   Phase 1   NCT01456468   United States
Aramchol meglumine
   Galmed Pharmaceuticals Ltd
      2025   Phase 2   NCT06095986   United States
Atra
   Yale University
      2011   Phase 1   NCT01456468   United States
Azathioprine
   Osaka General Medical Center
      2012   -   JPRN-UMIN000029482   Japan
   Tajiri Hitoshi
      2012   Phase 2   JPRN-jRCTs051180120   -
AZT
   Tajiri Hitoshi
      2012   Phase 2   JPRN-jRCTs051180120   -
Befizal L.P. 400 MG, comprimé enrobé à LIBération prolongéE
   ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
      2020   Phase 3   EUCTR2019-001015-23-FR   France
Bexotegrast
   Pliant Therapeutics, Inc
      2021   Phase 2   EUCTR2020-001428-33-NL   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
      2021   Phase 2   EUCTR2020-001428-33-DE   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
      2020   Phase 2   EUCTR2020-001428-33-BE   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;Norway;United Kingdom;United States
      2020   Phase 2   EUCTR2020-001428-33-AT   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
Bezafibrate
   ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
      2020   Phase 3   EUCTR2019-001015-23-FR   France
   Academic Medical Center
      2017   Phase 2   EUCTR2014-001438-27-ES   Netherlands;Spain
   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
      2016   Phase 3   NCT02701166   Netherlands;Spain
Bezafibrate (400MG) IN addition TO standard 15-20 MG/KG/jour udca therapy
   Assistance Publique - Hôpitaux de Paris
      2021   Phase 3   NCT04309773   France
Bezalip
   Academic Medical Center
      2017   Phase 2   EUCTR2014-001438-27-ES   Netherlands;Spain
      2015   -   EUCTR2014-001438-27-NL   Netherlands
Blood draw FOR THE laboratory assessment
   Mayo Clinic
      2025   Phase 2   NCT06905054   United States
Bromlein
   National Nutrition and Food Technology Institute
      2024   -   NCT06351696   Iran, Islamic Republic of
BRS201
   Brigham and Women's Hospital
      2023   Phase 2   NCT05835505   United States
BTT1023
   University of Birmingham
      2015   Phase 2   NCT02239211   United Kingdom
BTT1023 IV infusion 20 MG/ML, 5 ML drug product
   University of Birmingham
      2015   Phase 2   EUCTR2014-002393-37-GB   United Kingdom
Budesonide
   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
      1997   Phase 1   NCT00004842   United States
C10ab02
   ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
      2020   Phase 3   EUCTR2019-001015-23-FR   France
Capecitabine
   Azienda Ospedaliera di Padova
      2012   -   NCT01549795   Italy
Cenicriviroc 150 MG
   Tobira Therapeutics, Inc.
      2016   Phase 2   NCT02653625   Canada;United States
Cilo
   Gilead Sciences
      2019   Phase 1   NCT04060147   United States
Cilofexor
   GILEAD SCIENCES INCORPORATED
      2019   Phase 3   EUCTR2019-000204-14-IT   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
   Gilead Sciences
      2019   Phase 3   NCT03890120   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;New Zealand;Spain;Switzerland;United Kingdom;United States
      2016   Phase 2   NCT02943460   Austria;Canada;United Kingdom;United States
      2016   Phase 1   NCT02808312   New Zealand;United States
   Gilead Sciences, Inc.
      2019   Phase 3   EUCTR2019-000204-14-GB   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-FR   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-FI   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-ES   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-DK   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-BE   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-AT   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
   Gilead Sciences, K.K.
      2019   Phase 3   JPRN-jRCT2080224728   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;New Zealand;Spain;Switzerland;US;United Kingdom
CIS-4-hydroxy-L-proline
   RIEMSER Arzneimittel AG
      2005   -   EUCTR2005-001454-24-LT   Lithuania
Cladribine
   National Center for Research Resources (NCRR)
      1994   Phase 2   NCT00004762   -
CM-101
   ChemomAb Ltd
      2022   Phase 2   EUCTR2019-002945-39-ES   Israel;Spain;United Kingdom
      2020   Phase 2   EUCTR2019-002945-39-GB   Israel;United Kingdom
   ChemomAb Ltd.
      2020   Phase 2   NCT04595825   Germany;Israel;Spain;United Kingdom;United States
      2019   Phase 1   NCT06037577   Israel
      2019   Phase 2   EUCTR2018-004258-77-GB   Israel;United Kingdom
Contrast media, magnetic resonance
   Massachusetts General Hospital
      2024   -   NCT06252610   United States
CS0159
   Cascade Pharmaceuticals, Inc
      2023   Phase 2   NCT05896137   China
      2021   Phase 1   NCT05082779   United States
Curcumin
   John E. Eaton
      2017   Phase 1/Phase 2   NCT02978339   United States
DHA
   Beth Israel Deaconess Medical Center
      2005   Phase 1   NCT00325013   United States
Docosahexaenoic acid
   Beth Israel Deaconess Medical Center
      2005   Phase 1   NCT00325013   United States
DUR-928
   Durect
      2018   Phase 2   NCT03394781   United States
Elafibranor
   Ipsen Bioscience, Inc.
      2023   Phase 2   EUCTR2022-002695-37-PT   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-ES   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-DE   Canada;Germany;Italy;Portugal;Spain;United Kingdom;United States
Elafibranor 120 MG
   Ipsen
      2022   Phase 2   NCT05627362   Canada;Germany;Italy;Portugal;Spain;United Kingdom;United States
Elafibranor 80 MG
   Ipsen
      2022   Phase 2   NCT05627362   Canada;Germany;Italy;Portugal;Spain;United Kingdom;United States
Endoluminal bile duct brachytherapy
   Azienda Ospedaliera di Padova
      2012   -   NCT01549795   Italy
Engineered recombinant human FGF19
   NGM Biopharmaceuticals, Inc.
      2016   Phase 2   EUCTR2015-003392-30-NL   France;Netherlands;United Kingdom;United States
      2016   Phase 2   EUCTR2015-003392-30-GB   France;Netherlands;United Kingdom;United States
Entyvio
   TAKEDA DEVELOPMENT CENTRE EUROPE LTD
      2016   Phase 3   EUCTR2014-003942-28-IT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
   Takeda Development Centre Europe, Ltd.
      2016   Phase 3   EUCTR2014-003942-28-SE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-PL   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-HU   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-GB   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-FR   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-ES   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-DE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-CZ   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-BE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-AT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
EP547
   Escient Pharmaceuticals, Inc
      2022   Phase 2   NCT05525520   Belgium;Canada;France;Israel;Netherlands;Spain;United Kingdom;United States
EP547 tablet 25MG
   Escient Pharmaceuticals, Inc.
      2022   Phase 2   EUCTR2021-002526-25-FR   Belgium;Canada;France;Israel;Netherlands;Spain;United Kingdom;United States
EP547 tablet 75MG
   Escient Pharmaceuticals, Inc.
      2022   Phase 2   EUCTR2021-002526-25-FR   Belgium;Canada;France;Israel;Netherlands;Spain;United Kingdom;United States
Erlotinib
   Mayo Clinic
      2009   Phase 1   NCT00955149   United States
Faecal microbiota transplant
   University of Birmingham
      2024   Phase 2   NCT06286709   United Kingdom
Fecal microbiota transplantation
   Brigham and Women's Hospital
      2016   Phase 1/Phase 2   NCT02424175   United States
   Keio University, School of Medicine
      2019   -   JPRN-UMIN000036121   Japan
Fenofibrate
   Mayo Clinic
      2025   Phase 2   NCT06905054   United States
   University of Miami
      2010   Phase 1/Phase 2   NCT01142323   United States
Fluimucil*20CPR EFF 600MG
   POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
      2012   -   EUCTR2012-004170-26-IT   Italy
Genetic analysis
   Mayo Clinic
      2002   -   NCT01161992   United States
GFT505
   Ipsen Bioscience, Inc.
      2023   Phase 2   EUCTR2022-002695-37-PT   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-ES   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-DE   Canada;Germany;Italy;Portugal;Spain;United Kingdom;United States
Gluten-free diet
   Institute for Clinical and Experimental Medicine
      2023   -   NCT06026449   Czechia
   Universitätsklinikum Hamburg-Eppendorf
      2017   -   NCT04006886   Germany
GS-6624
   Gilead Sciences Inc
      2013   Phase 2   EUCTR2012-002473-61-SE   Belgium;Canada;Denmark;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-NL   Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-IT   Belgium;Canada;Denmark;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-GB   Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-ES   Belgium;Canada;Denmark;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-DK   Belgium;Canada;Denmark;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-DE   Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
      2013   Phase 2   EUCTR2012-002473-61-BE   Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States
GS-9674
   GILEAD SCIENCES INCORPORATED
      2019   Phase 3   EUCTR2019-000204-14-IT   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
   Gilead Sciences, Inc.
      2019   Phase 3   EUCTR2019-000204-14-GB   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-FR   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-FI   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-ES   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-DK   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-BE   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2019   Phase 3   EUCTR2019-000204-14-AT   Australia;Austria;Belgium;Canada;Denmark;Finland;France;Germany;Israel;Italy;Japan;Netherlands;New Zealand;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 2   EUCTR2016-002442-23-GB   Austria;Canada;United Kingdom;United States
      2017   Phase 2   EUCTR2016-002442-23-AT   Austria;Canada;United Kingdom;United States
HK-660S
   CuromeBiosciences
      2021   Phase 2   NCT05866809   Korea, Republic of
HK-660S 100MG
   CuromeBiosciences
      2025   Phase 2   NCT06975150   -
HK-660S 200MG
   CuromeBiosciences
      2025   Phase 2   NCT06975150   -
HTD1801
   HighTide Biopharma Pty Ltd
      2021   Phase 2   NCT03678480   -
      2018   Phase 2   NCT03333928   Canada;United States
      2017   Phase 1   NCT03099603   Australia
Humanised IGG1 monoclonal antibody against human eotaxin-2
   ChemomAb Ltd
      2022   Phase 2   EUCTR2019-002945-39-ES   Israel;Spain;United Kingdom
      2020   Phase 2   EUCTR2019-002945-39-GB   Israel;United Kingdom
Hymecromone
   Aparna Goel
      2023   Phase 2   NCT05295680   United States
ICG
   University of Aarhus
      2013   Phase 1   NCT01879735   Denmark
INT-747, OCA
   INTERCEPT PHARMACEUTICALS INC.
      2015   Phase 2   EUCTR2014-002205-38-IT   Italy;United States
IPN60190
   Ipsen Bioscience, Inc.
      2023   Phase 2   EUCTR2022-002695-37-PT   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-ES   Canada;France;Germany;Italy;Portugal;Spain;United Kingdom;United States
      2023   Phase 2   EUCTR2022-002695-37-DE   Canada;Germany;Italy;Portugal;Spain;United Kingdom;United States
LB-P8 HIGH-dose
   LISCure Biosciences
      2025   Phase 2   NCT06699121   United States
LB-P8 LOW-dose
   LISCure Biosciences
      2025   Phase 2   NCT06699121   United States
Levovanox
   UNIVERSITÀ DEGLI STUDI MILANO BICOCCA
      2022   Phase 2   EUCTR2022-000875-37-IT   Italy
Liver transplantation
   Keio University Hospital
      2016   -   JPRN-UMIN000022897   Japan
LUM001
   Lumena Pharmaceuticals LLC
      2015   Phase 2   EUCTR2014-005558-21-GB   United Kingdom;United States
   Mirum Pharmaceuticals, Inc.
      2014   Phase 2   NCT02061540   Canada;United Kingdom;United States
MBX-8025
   CymaBay Therapeutics
      2019   Phase 2   EUCTR2019-001760-30-PL   Australia;Canada;Germany;Israel;Poland;United Kingdom;United States
      2019   Phase 2   EUCTR2019-001760-30-GB   Australia;Canada;Germany;Israel;Poland;United Kingdom;United States
Methionine
   Medical University of Warsaw
      2023   -   NCT06026865   Poland
Metronidazole
   Keio University, School of Medicine
      2016   -   JPRN-UMIN000021411   Japan
   Mayo Clinic
      2010   Phase 1   NCT01085760   United States
Minocycline
   Mayo Clinic
      2003   Phase 1   NCT00630942   United States
Mitomycin C
   Li, Zhiping, M.D.
      2012   Phase 2   NCT01688024   United States
Mizoribine
   Osaka General Medical Center
      2012   -   JPRN-UMIN000029482   Japan
   Tajiri Hitoshi
      2012   Phase 2   JPRN-jRCTs051180120   -
MLN0002
   TAKEDA DEVELOPMENT CENTRE EUROPE LTD
      2016   Phase 3   EUCTR2014-003942-28-IT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
   Takeda Development Centre Europe, Ltd.
      2016   Phase 3   EUCTR2014-003942-28-SE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-PL   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-HU   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-GB   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-FR   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-ES   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-DE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-CZ   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-BE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-AT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
NGM282
   NGM Biopharmaceuticals, Inc
      2016   Phase 2   NCT02704364   France;Netherlands;United Kingdom;United States
   NGM Biopharmaceuticals, Inc.
      2016   Phase 2   EUCTR2015-003392-30-NL   France;Netherlands;United Kingdom;United States
      2016   Phase 2   EUCTR2015-003392-30-GB   France;Netherlands;United Kingdom;United States
Normal saline
   Li, Zhiping, M.D.
      2012   Phase 2   NCT01688024   United States
Norucholic acid
   Dr. Falk Pharma GmbH
      2025   Phase 3   NCT06886360   -
      2019   Phase 3   EUCTR2016-003367-19-NL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-SE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-PL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-FI   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-DK   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-CZ   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-BE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-LT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-DE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-AT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      -   Phase 3   EUCTR2016-003367-19-NO   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
Norudca
   DR. FALK PHARMA GMBH
      2018   Phase 3   EUCTR2016-003367-19-IT   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Sweden;Switzerland;United Kingdom
   Dr. Falk Pharma GmbH
      2019   Phase 3   EUCTR2016-003367-19-NL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-SE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-PL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-GB   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-FR   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-FI   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-DK   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-CZ   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-BE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-LT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-HU   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-DE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-AT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2014   -   EUCTR2011-002754-31-BE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2013   Phase 2   EUCTR2011-002754-31-GB   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   Phase 2   NCT01755507   Austria;Germany;Norway
      2012   Phase 2   EUCTR2011-002754-31-SE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   Phase 2   EUCTR2011-002754-31-NO   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-NL   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-LT   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-HU   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-FI   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-ES   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-DK   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-DE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-AT   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2016-003367-19-NO   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      -   Phase 3   EUCTR2016-003367-19-IE   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Lithuania;Netherlands;Poland;Sweden;Switzerland;United Kingdom
Norursodeoxycholic acid
   DR. FALK PHARMA GMBH
      2018   Phase 3   EUCTR2016-003367-19-IT   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Sweden;Switzerland;United Kingdom
   Dr. Falk Pharma GmbH
      2018   Phase 3   NCT03872921   Austria;Germany
      2018   Phase 3   EUCTR2016-003367-19-GB   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-FR   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-HU   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2014   -   EUCTR2011-002754-31-BE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2013   Phase 2   EUCTR2011-002754-31-GB   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   Phase 2   EUCTR2011-002754-31-SE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   Phase 2   EUCTR2011-002754-31-NO   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-NL   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-LT   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-HU   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-FI   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-ES   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-DK   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-DE   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      2012   -   EUCTR2011-002754-31-AT   Austria;Belgium;Denmark;Finland;Germany;Hungary;Lithuania;Netherlands;Norway;Spain;Sweden;United Kingdom
      -   Phase 3   EUCTR2016-003367-19-IE   Austria;Belgium;Czech Republic;Denmark;Finland;France;Germany;Hungary;Ireland;Lithuania;Netherlands;Poland;Sweden;Switzerland;United Kingdom
Norursodeoxycholic acid, NCA
   Dr. Falk Pharma GmbH
      2019   Phase 3   EUCTR2016-003367-19-NL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-SE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-PL   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-FI   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-DK   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-CZ   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2018   Phase 3   EUCTR2016-003367-19-BE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-LT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-DE   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      2017   Phase 3   EUCTR2016-003367-19-AT   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
      -   Phase 3   EUCTR2016-003367-19-NO   Austria;Belgium;Czech Republic;Czechia;Denmark;Finland;France;Germany;Hungary;Ireland;Italy;Lithuania;Netherlands;Norway;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom
OCA
   Intercept Pharmaceuticals
      2015   Phase 2   NCT02177136   Austria;Belgium;France;Germany;Italy;Netherlands;Norway;Sweden;United Kingdom;United States
OCA 1,5 MG
   INTERCEPT PHARMACEUTICALS INC.
      2015   Phase 2   EUCTR2014-002205-38-IT   Italy;United States
OCA 5 MG
   INTERCEPT PHARMACEUTICALS INC.
      2015   Phase 2   EUCTR2014-002205-38-IT   Italy;United States
Oral vancomycin
   Sacramento Pediatric Gastroenterology
      2010   Phase 1   NCT02137668   United States
   Stanford University
      2012   Phase 3   NCT01802073   United States
   University Hospital Birmingham NHS Foundation Trust
      2022   -   NCT05376228   United Kingdom
   University of Milano Bicocca
      2023   Phase 2   NCT05876182   Italy
Oral vancomycin and oral amoxicillin
   University of Minnesota
      2024   Early Phase 1   NCT06197308   United States
Orbcel-C
   University of Birmingham
      2018   Phase 1/Phase 2   NCT02997878   United Kingdom
Phenylbutyrate
   Juntendo University
      2014   -   JPRN-UMIN000012782   Japan
   Saiseikai Yokohama City Tobu Hospital
      2010   -   JPRN-UMIN000003802   Japan
PLN-74809
   Pliant Therapeutics, Inc
      2021   Phase 2   EUCTR2020-001428-33-NL   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
      2021   Phase 2   EUCTR2020-001428-33-FR   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
      2021   Phase 2   EUCTR2020-001428-33-DE   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
      2020   Phase 2   EUCTR2020-001428-33-GB   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;Norway;United Kingdom;United States
      2020   Phase 2   EUCTR2020-001428-33-BE   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;Norway;United Kingdom;United States
      2020   Phase 2   EUCTR2020-001428-33-AT   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
   Pliant Therapeutics, Inc.
      2020   Phase 2   NCT04480840   Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom;United States
PRE liver transplantation laparoscopic hand assisted staging
   Azienda Ospedaliera di Padova
      2012   -   NCT01549795   Italy
Probiotics
   UMC Utrecht
      2005   Phase 3   NCT00161148   Netherlands
Radiotracer injection
   Massachusetts General Hospital
      2024   -   NCT06252610   United States
REC-H-FGF19
   NGM Biopharmaceuticals, Inc.
      2016   Phase 2   EUCTR2015-003392-30-NL   France;Netherlands;United Kingdom;United States
      2016   Phase 2   EUCTR2015-003392-30-GB   France;Netherlands;United Kingdom;United States
Ritivixibat
   Albireo, an Ipsen Company
      2023   Phase 2   NCT05642468   France;Italy;Poland;Spain
Rituximab
   Keio University Hospital
      2016   -   JPRN-UMIN000022897   Japan
Rosuvastatin
   Stanford University
      2023   Early Phase 1   NCT05912387   United States
Same
   Medical University of Warsaw
      2023   -   NCT06026865   Poland
Seladelpar
   CymaBay Therapeutics
      2019   Phase 2   EUCTR2019-001760-30-PL   Australia;Canada;Germany;Israel;Poland;United Kingdom;United States
      2019   Phase 2   EUCTR2019-001760-30-GB   Australia;Canada;Germany;Israel;Poland;United Kingdom;United States
   Gilead Sciences
      2019   Phase 2   NCT04024813   Canada;Poland;United States
Simtuzimab
   Gilead Sciences Inc
      2013   Phase 2   EUCTR2012-002473-61-IT   Belgium;Canada;Denmark;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
Simtuzumab
   Gilead Sciences
      2013   Phase 2   NCT01672853   Belgium;Canada;Denmark;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
   Gilead Sciences Inc
      2013   Phase 2   EUCTR2012-002473-61-IT   Belgium;Canada;Denmark;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom;United States
Simvastatin 40MG
   Annika Bergquist
      2020   Phase 3   NCT04133792   Sweden
Siplizumab
   Elizabeth C. Verna
      2024   Phase 1   NCT06455280   United States
Sulfasalazine
   Brigham and Women's Hospital
      2018   Phase 2   NCT03561584   United States
TBC
   ChemomAb Ltd
      2022   Phase 2   EUCTR2019-002945-39-ES   Israel;Spain;United Kingdom
      2020   Phase 2   EUCTR2019-002945-39-GB   Israel;United Kingdom
Thalidomide
   Mayo Clinic
      2006   Phase 2   NCT00953615   United States
Ucmsc
   Fuzhou General Hospital
      2017   Phase 1/Phase 2   NCT03516006   -
Udca
   Fuzhou General Hospital
      2017   Phase 1/Phase 2   NCT03516006   -
   University of Tennessee
      2010   Phase 1   NCT01088607   Canada;United States
Ursodeoxycholic acid
   HighTide Biopharma Pty Ltd
      2021   Phase 2   NCT03678480   -
   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
      2003   Phase 2/Phase 3   NCT00059202   United States
   University of Tennessee
      2010   Phase 1   NCT01088607   Canada;United States
Ursofalk
   Sahlgrenska Academy
      2015   Phase 3   EUCTR2015-003310-24-SE   Sweden
Ursolic acid
   University of California, Davis
      2017   Phase 1   NCT03216876   United States
Vancomicina cloridrato
   UNIVERSITÀ DEGLI STUDI MILANO BICOCCA
      2022   Phase 2   EUCTR2022-000875-37-IT   Italy
Vancomycin
   Elizabeth Carey
      2020   Phase 2/Phase 3   NCT03710122   Canada;United States
   Karolinska Institutet
      2013   -   EUCTR2009-018034-11-SE   Sweden
   Mayo Clinic
      2010   Phase 1   NCT01085760   United States
   Ochsner Health System
      2016   -   NCT03046901   United States
   Stanford University
      2007   Phase 1   NCT01322386   -
   Tehran University of Medical Sciences
      2015   Phase 4   NCT02605213   Iran, Islamic Republic of
   University of Minnesota
      2015   Phase 1   NCT02464020   United States
Vedolizumab
   Takeda
      2017   Phase 3   NCT03035058   -
Vedolizumab IV
   Takeda Development Centre Europe, Ltd.
      2016   Phase 3   EUCTR2014-003942-28-SE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-PL   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-HU   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-GB   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-FR   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-ES   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-DE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-CZ   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-BE   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
      2016   Phase 3   EUCTR2014-003942-28-AT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Denmark;Finland;France;Germany;Hungary;Israel;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States
Vidofludimus calcium
   Elizabeth Carey
      2019   Phase 2   NCT03722576   United States
Volixibat
   Mirum Pharmaceuticals, Inc.
      2020   Phase 2   NCT04663308   Argentina;Australia;Belgium;Brazil;Canada;France;Germany;Israel;Italy;Netherlands;Spain;Switzerland;United Kingdom;United States
Volixibat potassium
   Mirum Pharmaceuticals, Inc.
      2021   Phase 2   EUCTR2020-003027-41-DE   Canada;Germany;Israel;United Kingdom;United States
Xifaxan
   Mayo Clinic
      2012   Phase 1   NCT01695174   United States