Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetylcysteine 4件: ACETYLCYSTEINE; N acetyl cysteine; N-acetyl cysteine; N-acetylcysteine1件: Acetylcysteine 💬 --25件: 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
2 Alanine 2件: Alanine; L-alanine1件: Alanine 💬 --8件: 6, 13, 70, 94, 97, 251, 298, 299 💬
3 Aldafermin 1件: Aldafermin1件: Aldafermin 💬 1件: FGF19 💬 10件: Breast cancer, Calcium signaling pathway, Gastric cancer, MAPK signaling pathway, Melanoma, PI3K-Akt signaling pathway, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬1件: 94 💬
4 Amoxicillin 2件: Amoxicilina; AMOXICILLIN3件: Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--9件: 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
5 Aramchol 1件: Aramchol---2件: 94, 265 💬
6 Azathioprine 2件: Azathioprine; AZATIOPRINA2件: Azathioprine ,
Azathioprine sodium 💬 		--26件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
7 Bexotegrast 1件: Bexotegrast1件: Bexotegrast 💬 3件: ITGA5,
ITGB1,
ITGB6 💬 		33件: Arrhythmogenic right ventricular cardiomyopathy, Axon guidance, Bacterial invasion of epithelial cells, Cell adhesion molecule (CAM) interaction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IgSF CAM signaling, Integrin signaling, Leishmaniasis, Leukocyte transendothelial migration, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Phagocytosis, Platelet activation, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Small cell lung cancer, Tight junction, Toxoplasmosis, Virion - Herpesvirus, Virion - Rotavirus, Yersinia infection 💬1件: 94 💬
8 Bezafibrate 1件: Bezafibrate1件: Bezafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
9 Budesonide 1件: BUDESONIDE1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
10 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
11 Capecitabine 1件: Capecitabine1件: Capecitabine 💬 1件: TYMS 💬 3件: Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬1件: 94 💬
12 Cenicriviroc 1件: Cenicriviroc2件: Cenicriviroc ,
Cenicriviroc mesylate 💬 		2件: CCR2,
CCR5 💬 		11件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬1件: 94 💬
13 Cilofexor 1件: Cilofexor---2件: 93, 94 💬
14 Cladribine 2件: CLADRIBINA; CLADRIBINE1件: Cladribine 💬 1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94 💬
15 CM-101 1件: CM-101---2件: 51, 94 💬
16 Curcumin 1件: Curcumin---12件: 2, 13, 34, 36, 46, 67, 74, 94, 96, 97, 139, 299 💬
17 Elafibranor 1件: ELAFIBRANOR1件: Elafibranor 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
18 Erlotinib 1件: Erlotinib2件: Erlotinib hydrochloride ,
Erlotinib 💬 		1件: EGFR 💬 49件: Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬2件: 94, 160 💬
19 Fecal microbiota 3件: Fecal microbial transplantation; Fecal microbiota; Fecal Microbiota Transplantation---14件: 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
20 Fenofibrate 1件: Fenofibrate1件: Fenofibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
21 Hymecromone 1件: Hymecromone1件: Hymecromone 💬 --2件: 85, 94 💬
22 LB-P8 1件: LB-P8---2件: 46, 94 💬
23 Meglumine 1件: Meglumine1件: Meglumine 💬 --4件: 28, 53, 85, 94 💬
24 Methionine 2件: L-methionine; Methionine1件: Methionine 💬 --9件: 34, 75, 84, 93, 94, 229, 298, 300, 337 💬
25 Metronidazole 2件: Metronidazol; METRONIDAZOLE2件: Metronidazole ,
Metronidazole hydrochloride 💬 		--7件: 46, 51, 63, 94, 96, 97, 291 💬
26 Minocycline 2件: Minocycline; MINOCYCLINE HYDROCHLORIDE2件: Minocycline hydrochloride ,
Minocycline 💬 		--14件: 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
27 Mitomycin 2件: Mitomycin; Mitomycin C1件: Mitomycin 💬 --3件: 94, 162, 329 💬
28 Mizoribine 1件: Mizoribine1件: Mizoribine 💬 2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
29 norUrsodeoxycholic acid 2件: Norucholic acid; NorUrsodeoxycholic Acid1件: Norucholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬1件: 94 💬
30 Potassium 1件: Potassium1件: Potassium 💬 --17件: 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
31 Proline 1件: Proline1件: Proline 💬 --3件: 66, 94, 97 💬
32 Ritivixibat 1件: Ritivixibat---1件: 94 💬
33 Rituximab 1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
34 Rosuvastatin 2件: Rosuvastatin; ROSUVASTATIN CALCIUM2件: Rosuvastatin calcium ,
Rosuvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬16件: 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
35 Seladelpar 1件: SELADELPAR2件: Seladelpar ,
Seladelpar lysine 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
36 Simtuzumab 2件: GS-6624; Simtuzumab---2件: 85, 94 💬
37 Simvastatin 2件: Simvastatin; Simvastatine1件: Simvastatin 💬 1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬22件: 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
38 Siplizumab 1件: Siplizumab1件: Siplizumab 💬 1件: CD2 💬 3件: Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage, IgSF CAM signaling 💬2件: 94, 95 💬
39 Sulfasalazine 2件: Sulfasalazine; Sulphasalazine1件: Sulfasalazine 💬 --7件: 46, 49, 86, 94, 107, 270, 271 💬
40 Thalidomide 1件: Thalidomide1件: Thalidomide 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬22件: 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
41 Ursodeoxycholic acid 3件: UDCA; Ursodeoxycholic Acid; Ursodiol1件: Ursodiol 💬 1件: NR1H4 💬 1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
42 Ursolic acid 1件: Ursolic acid---1件: 94 💬
43 Vancomycin 1件: Vancomycin2件: Vancomycin ,
Vancomycin hydrochloride 💬 		--9件: 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
44 Vedolizumab 1件: VEDOLIZUMAB1件: Vedolizumab 💬 2件: ITGA4,
ITGB7 💬 		18件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecule (CAM) interaction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, IgSF CAM signaling, Integrin signaling, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97 💬
45 Vidofludimus 2件: Vidofludimus; Vidofludimus calcium2件: Vidofludimus ,
Vidofludimus calcium 💬 		1件: DHODH 💬 1件: Pyrimidine metabolism 💬5件: 13, 46, 94, 96, 97 💬
46 Volixibat 2件: Volixibat; Volixibat potassium2件: Volixibat potassium ,
Volixibat 💬 		--2件: 93, 94 💬