140. Dorabe syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 116 / Drugs : 65 - (DrugBank : 17) / Drug target genes : 50 - Drug target pathways : 64
Dorabe syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
140 | Dorabe syndrome | - |
6 | Parkinson disease | 46.266 |
144 | Lennox-Gastaut syndrome | 41.250 |
156 | Rett syndrome | 38.205 |
2 | Amyotrophic lateral sclerosis | 38.032 |
13 | Multiple sclerosis/Neuromyelitis optica | 37.579 |
97 | Ulcerative colitis | 36.735 |
193 | Prader-Willi syndrome | 35.982 |
8 | Huntington disease | 35.083 |
17 | Multiple system atrophy | 26.929 |
206 | Fragile X syndrome | 26.324 |
201 | Angelman syndrome | 22.000 |
298 | Hereditary pancreatitis | 21.205 |
18 | Spinocerebellar degeneration | 20.969 |
5 | Progressive supranuclear palsy | 20.094 |
145 | West syndrome | 19.793 |
70 | Spinal stenosis | 18.778 |
3 | Spinal muscular atrophy | 18.671 |
272 | Fibrodysplasia ossificans progressiva | 17.308 |
96 | Crohn disease | 17.086 |
36 | Epidermolysis bullosa | 16.644 |
231 | Alpha-1-antitrypsin deficiency | 16.275 |
152 | PCDH19 related syndrome | 16.000 |
46 | Malignant rheumatoid arthritis | 14.640 |
155 | Acquired aphasia with convulsive disorder | 13.733 |
158 | Tuberous sclerosis | 12.536 |
84 | Sarcoidosis | 12.213 |
205 | Fragile X syndrome related disease | 12.160 |
34 | Neurofibromatosis | 12.039 |
22 | Moyamoya disease | 11.429 |
21 | Mitochondrial disease | 11.059 |
98 | Eosinophilic gastrointestinal disease | 10.573 |
296 | Biliary atresia | 9.126 |
75 | Cushing disease | 9.031 |
203 | 22q11.2 deletion syndrome | 6.388 |
86 | Pulmonary arterial hypertension | 6.234 |
90 | Retinitis pigmentosa | 5.204 |
226 | Interstitial cystitis with Hunners ulcer | 4.688 |
51 | Scleroderma | 3.346 |
114 | Non-dystrophic myotonia syndrome | 3.346 |
58 | Hypertrophic cardiomyopathy | 3.059 |
7 | Corticobasal degeneration | 3.009 |
168 | Ehlers-Danlos syndrome | 3.009 |
1 | Spinal and bulbar muscular atrophy | 2.760 |
149 | Hemiconvulsion hemiplegia epilepsy syndrome | 2.603 |
10 | Charcot-Marie-Tooth disease | 2.557 |
4 | Primary lateral sclerosis | 2.408 |
309 | Progressive myoclonus epilepsy | 2.297 |
127 | Frontotemporal lobar degeneration | 2.067 |
38 | Stevens-Johnson syndrome | 2.014 |
74 | Prolactin secreting pituitary adenoma | 1.921 |
167 | Marfan syndrome | 1.800 |
164 | Oculocutaneous albinism | 1.676 |
81 | Congenital adrenal hyperplasia | 1.556 |
299 | Cystic fibrosis | 1.457 |
187 | Kabuki syndrome | 1.361 |
256 | Muscle glycogenosis | 1.243 |
179 | Williams syndrome | 1.125 |
254 | Porphyria | 1.105 |