156. Rett syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 63 / Drugs : 79 - (DrugBank : 29) / Drug target genes : 100 - Drug target pathways : 116
Rett syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 156 | Rett syndrome | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 75.295 |
| 2 | Amyotrophic lateral sclerosis | 60.189 |
| 96 | Crohn disease | 47.218 |
| 6 | Parkinson disease | 43.883 |
| 140 | Dorabe syndrome | 38.205 |
| 97 | Ulcerative colitis | 37.287 |
| 144 | Lennox-Gastaut syndrome | 36.470 |
| 8 | Huntington disease | 33.733 |
| 193 | Prader-Willi syndrome | 33.094 |
| 206 | Fragile X syndrome | 32.297 |
| 5 | Progressive supranuclear palsy | 28.720 |
| 18 | Spinocerebellar degeneration | 27.971 |
| 17 | Multiple system atrophy | 25.596 |
| 3 | Spinal muscular atrophy | 23.313 |
| 70 | Spinal stenosis | 21.179 |
| 298 | Hereditary pancreatitis | 19.595 |
| 205 | Fragile X syndrome related disease | 18.556 |
| 46 | Malignant rheumatoid arthritis | 18.502 |
| 21 | Mitochondrial disease | 17.097 |
| 272 | Fibrodysplasia ossificans progressiva | 16.583 |
| 145 | West syndrome | 16.162 |
| 152 | PCDH19-related syndrome | 16.000 |
| 98 | Eosinophilic gastro-intestinal disorder | 15.919 |
| 231 | Alpha-1-antitrypsin deficiency | 14.891 |
| 36 | Epidermolysis bullosa | 14.441 |
| 203 | 22q11.2 deletion syndrome | 14.000 |
| 201 | Angelman syndrome | 13.989 |
| 296 | Biliary atresia | 12.855 |
| 155 | Acquired aphasia with convulsive disorder | 12.768 |
| 158 | Tuberous sclerosis | 12.458 |
| 84 | Sarcoidosis | 11.394 |
| 34 | Neurofibromatosis | 11.134 |
| 22 | Moyamoya disease | 10.568 |
| 226 | Interstitial cystitis with Hunners ulcer | 8.087 |
| 86 | Pulmonary arterial hypertension | 7.408 |
| 75 | Cushing disease | 7.385 |
| 127 | Frontotemporal lobar degeneration | 5.706 |
| 113 | Muscular dystrophy | 3.329 |
| 299 | Cystic fibrosis | 3.136 |
| 58 | Hypertrophic cardiomyopathy | 3.111 |
| 114 | Non-dystrophic myotonia syndrome | 3.111 |
| 254 | Porphyria | 2.981 |
| 51 | Scleroderma | 2.946 |
| 168 | Ehlers-Danlos syndrome | 2.922 |
| 53 | Sjogren syndrome | 2.881 |
| 78 | Hypopituitarism | 2.678 |
| 1 | Spinal and bulbar muscular atrophy | 2.662 |
| 10 | Charcot-Marie-Tooth disease | 2.450 |
| 4 | Primary lateral sclerosis | 2.215 |
| 120 | Hereditary dystonia | 2.000 |
| 179 | Williams syndrome | 1.893 |
| 38 | Stevens-Johnson syndrome | 1.883 |
| 167 | Marfan syndrome | 1.725 |
| 49 | Systemic lupus erythematosus | 1.679 |
| 215 | Tetralogy of Fallot | 1.623 |
| 90 | Retinitis pigmentosa | 1.545 |
| 256 | Muscle glycogenosis | 1.538 |
| 81 | Congenital adrenal hyperplasia | 1.472 |
| 187 | Kabuki syndrome | 1.351 |
| 50 | Dermatomyositis | 1.159 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 1.100 |
| 85 | Idiopathic interstitial pneumonia | 1.086 |