167. Marfan syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 26 / Drugs : 50 - (DrugBank : 11) / Drug target genes : 10 - Drug target pathways : 52
Marfan syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 167 | Marfan syndrome | - |
| 96 | Crohn disease | 8.148 |
| 86 | Pulmonary arterial hypertension | 6.528 |
| 6 | Parkinson disease | 6.468 |
| 67 | Polycystic kidney disease | 5.287 |
| 58 | Hypertrophic cardiomyopathy | 5.206 |
| 70 | Spinal stenosis | 5.123 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.825 |
| 97 | Ulcerative colitis | 3.701 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 3.654 |
| 193 | Prader-Willi syndrome | 2.745 |
| 17 | Multiple system atrophy | 2.705 |
| 57 | Idiopathic dilated cardiomyopathy | 2.667 |
| 46 | Malignant rheumatoid arthritis | 2.568 |
| 81 | Congenital adrenal hyperplasia | 2.400 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 2.160 |
| 215 | Tetralogy of Fallot | 2.133 |
| 272 | Fibrodysplasia ossificans progressiva | 1.969 |
| 140 | Dorabe syndrome | 1.800 |
| 50 | Dermatomyositis | 1.800 |
| 144 | Lennox-Gastaut syndrome | 1.796 |
| 90 | Retinitis pigmentosa | 1.796 |
| 298 | Hereditary pancreatitis | 1.781 |
| 113 | Muscular dystrophy | 1.763 |
| 156 | Rett syndrome | 1.725 |
| 51 | Scleroderma | 1.685 |
| 169 | Menkes disease | 1.600 |
| 170 | Occipital horn syndrome | 1.600 |
| 227 | Osler disease | 1.174 |
| 22 | Moyamoya disease | 1.125 |
| 210 | Single Ventricle | 1.097 |
| 66 | IgA nephropathy | 1.080 |
| 158 | Tuberous sclerosis | 1.080 |
| 296 | Biliary atresia | 1.040 |
| 11 | Myasthenia gravis | 1.040 |
| 157 | Sturge-Weber syndrome | 1.040 |
| 222 | Primary nephrotic syndrome | 1.003 |
| 111 | Congenital myopathy | 1.000 |