205. Fragile X syndrome related disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 5 / Drugs : 11 - (DrugBank : 7) / Drug target genes : 25 - Drug target pathways : 31
Fragile X syndrome related disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 205 | Fragile X syndrome related disease | - |
| 2 | Amyotrophic lateral sclerosis | 21.406 |
| 46 | Malignant rheumatoid arthritis | 21.389 |
| 13 | Multiple sclerosis | 21.319 |
| 18 | Spinocerebellar degeneration | 20.651 |
| 3 | Spinal muscular atrophy | 20.456 |
| 70 | Spinal stenosis | 20.240 |
| 97 | Ulcerative colitis | 19.766 |
| 96 | Crohn disease | 19.706 |
| 6 | Parkinson disease | 19.669 |
| 21 | Mitochondrial disease | 19.141 |
| 206 | Fragile X syndrome | 18.947 |
| 17 | Multiple system atrophy | 18.797 |
| 5 | Progressive supranuclear palsy | 18.726 |
| 156 | Rett syndrome | 18.556 |
| 8 | Huntington disease | 18.480 |
| 75 | Cushing disease | 17.290 |
| 145 | West syndrome | 16.320 |
| 152 | PCDH19 related syndrome | 16.000 |
| 201 | Angelman syndrome | 14.429 |
| 84 | Sarcoidosis | 14.066 |
| 98 | Eosinophilic gastro-intestinal disorder | 13.816 |
| 272 | Fibrodysplasia ossificans progressiva | 13.785 |
| 296 | Biliary atresia | 13.615 |
| 22 | Moyamoya disease | 13.531 |
| 155 | Acquired aphasia with convulsive disorder | 13.418 |
| 193 | Prader-Willi syndrome | 13.373 |
| 298 | Hereditary pancreatitis | 13.305 |
| 231 | Alpha-1-antitrypsin deficiency | 12.873 |
| 158 | Tuberous sclerosis | 12.873 |
| 140 | Dorabe syndrome | 12.160 |
| 36 | Epidermolysis bullosa | 12.121 |
| 144 | Lennox-Gastaut syndrome | 12.121 |
| 34 | Neurofibromatosis | 11.299 |
| 78 | Hypopituitarism | 2.762 |
| 113 | Muscular dystrophy | 2.558 |
| 203 | 22q11.2 deletion syndrome | 2.429 |
| 49 | Systemic lupus erythematosus | 2.269 |
| 127 | Frontotemporal lobar degeneration | 2.124 |
| 215 | Tetralogy of Fallot | 2.111 |
| 4 | Primary lateral sclerosis | 2.053 |
| 85 | Idiopathic interstitial pneumonia | 1.716 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |