210. Single Ventricle Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 56 / Drugs : 49 - (DrugBank : 25) / Drug target genes : 35 - Drug target pathways : 77
Single Ventricle and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 210 | Single Ventricle | - |
| 46 | Malignant rheumatoid arthritis | 17.335 |
| 85 | Idiopathic interstitial pneumonia | 11.557 |
| 49 | Systemic lupus erythematosus | 10.220 |
| 2 | Amyotrophic lateral sclerosis | 8.744 |
| 86 | Pulmonary arterial hypertension | 8.227 |
| 51 | Scleroderma | 8.089 |
| 28 | Systemic amyloidosis | 7.795 |
| 266 | Familial mediterranean fever | 6.690 |
| 93 | Primary biliary cholangitis | 5.089 |
| 42 | Polyarteritis nodosa | 4.770 |
| 34 | Neurofibromatosis | 4.694 |
| 65 | Primary immunodeficiency | 4.664 |
| 299 | Cystic fibrosis | 4.608 |
| 331 | Idiopathic multicentric castleman disease | 4.409 |
| 57 | Idiopathic dilated cardiomyopathy | 4.375 |
| 113 | Muscular dystrophy | 4.290 |
| 6 | Parkinson disease | 4.204 |
| 56 | Behcet disease | 4.148 |
| 26 | HTLV-1-associated myelopathy | 4.063 |
| 96 | Crohn disease | 3.534 |
| 212 | Tricuspid atresia | 3.418 |
| 13 | Multiple sclerosis | 3.383 |
| 169 | Menkes disease | 3.125 |
| 170 | Occipital horn syndrome | 3.125 |
| 58 | Hypertrophic cardiomyopathy | 3.000 |
| 22 | Moyamoya disease | 2.898 |
| 222 | Primary nephrotic syndrome | 2.787 |
| 70 | Spinal stenosis | 2.727 |
| 67 | Polycystic kidney disease | 2.539 |
| 11 | Myasthenia gravis | 2.382 |
| 118 | Myelomeningocele | 2.250 |
| 17 | Multiple system atrophy | 2.159 |
| 5 | Progressive supranuclear palsy | 2.120 |
| 337 | Homocystinuria | 2.000 |
| 139 | Congenital cerebral hypomyelination | 2.000 |
| 8 | Huntington disease | 1.987 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.953 |
| 211 | Hypoplastic left heart syndrome | 1.913 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 1.913 |
| 218 | Alport syndrome | 1.641 |
| 47 | Buerger disease | 1.641 |
| 88 | Chronic thromboembolic pulmonary hypertension | 1.577 |
| 225 | Congenital nephrogenic diabetes insipidus | 1.484 |
| 80 | Resistance to thyroid hormone | 1.375 |
| 78 | Hypopituitarism | 1.261 |
| 206 | Fragile X syndrome | 1.172 |
| 167 | Marfan syndrome | 1.097 |
| 251 | Urea cycle disorder | 1.062 |
| 111 | Congenital myopathy | 1.000 |