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215. Tetralogy of Fallot Disease details / Clinical trials / Drug dev / DR info

Clinical trials : 28 / Drugs : 55 - (DrugBank : 19) / Drug target genes : 16 - Drug target pathways : 50

Drugs, Primary sponsors and Trial info (Enrollment year, Phase, Trial ID, Countries)

Alpha-tocopherol
   Dr Cipto Mangunkusumo General Hospital
      2022   Early Phase 1   NCT07194304   Indonesia
Blood cardioplegia
   SUNDER LAL NEGI
      2014   Phase 4   NCT02646254   -
Blood draw
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Calcium gluconate
   National Center for Research Resources (NCRR)
      1995   -   NCT00004361   -
Cellvizio 100 series system with confocal miniprobes
   Aditya Kaza
      2019   Phase 2   NCT04017975   United States
Central venous line placement
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Chest X-RAY
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Cold cadioplegia
   Ain Shams University
      2021   Early Phase 1   NCT05176782   Egypt
Dapagliflozin
   The University of Hong Kong
      2025   Phase 4   NCT06668389   Hong Kong
DEL nido cardioplegia
   SUNDER LAL NEGI
      2014   Phase 4   NCT02646254   -
Dexmedetomidine
   Athena Zuppa
      2004   Phase 1   NCT00573066   -
   HealthCore-NERI
      2014   Phase 1   NCT01915277   United States
   Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
      2016   -   ChiCTR-IOR-16008571   China
Dexmedetomidine HCL 100 MCG/ML INJ
   National Cardiovascular Center Harapan Kita Hospital Indonesia
      2022   Phase 2/Phase 3   NCT05579964   Indonesia
Dobutamin
   Competence Network for Congenital Heart Defects
      2007   Phase 3   NCT00564993   Germany
Dobutamine
   Deutsche Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler
      2007   -   EUCTR2007-003461-41-DE   Germany
   University Hospital Tuebingen
      2007   -   NCT00557934   Germany
Echocardiogram
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States
Electrocardiogram
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Eplerenone
   Washington University School of Medicine
      2013   Phase 4   NCT01971593   United States
Fentanyl (LOW dose) + dexmedetomidine
   Nationwide Children's Hospital
      2008   Phase 2   NCT00848393   United States
Fluid administration
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Fluorescite
   Aditya Kaza
      2019   Phase 2   NCT04017975   United States
HTK cardioplegia
   Ain Shams University
      2021   Early Phase 1   NCT05176782   Egypt
Ketamine
   Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
      2016   -   ChiCTR-IOR-16008571   China
Losartan
   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
      2013   Phase 2   NCT02010905   Netherlands
Losartan potassium
   Academisch medisch centrum
      2014   -   EUCTR2013-002091-41-NL   Netherlands
N-thymidine
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States
N15-thymidine
   Weill Medical College of Cornell University
      2026   -   NCT06587165   United States
Physical exam
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States
Pregnancy test
   University of Wisconsin, Madison
      2014   -   NCT02967315   United States
Propranolol hydrochloride
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States
SGLT2 inhibitors
   Leiden University Medical Center
      2023   -   NCT06932081   Germany;Netherlands;North Macedonia;United Kingdom;United States
Sodium chloride
   Shanghai Children's Hospital
      2025   -   ChiCTR2500102350   China
   Shanghai Jiao Tong University School of Medicine
      2013   -   NCT01941576   China
Sodium citrate
   National Center for Research Resources (NCRR)
      1995   -   NCT00004361   -
Specimen collection
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States
Sterile water FOR injection
   Dr Cipto Mangunkusumo General Hospital
      2022   Early Phase 1   NCT07194304   Indonesia
Sulfur hexafluoride
   Nemours Children's Clinic
      2022   Phase 1/Phase 2   NCT05186415   United States
Tranexamic acid
   National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
      2018   -   ChiCTR1800019578   China
Urine collection
   Weill Medical College of Cornell University
      2022   Phase 1   NCT04713657   United States