22. Moyamoya disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 36 / Drugs : 44 - (DrugBank : 26) / Drug target genes : 36 - Drug target pathways : 37
Moyamoya disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 22 | Moyamoya disease | - |
| 70 | Spinal stenosis | 28.000 |
| 6 | Parkinson disease | 28.000 |
| 46 | Malignant rheumatoid arthritis | 28.000 |
| 96 | Crohn disease | 28.000 |
| 5 | Progressive supranuclear palsy | 26.436 |
| 17 | Multiple system atrophy | 23.419 |
| 2 | Amyotrophic lateral sclerosis | 22.711 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 22.573 |
| 206 | Fragile X syndrome | 22.095 |
| 158 | Tuberous sclerosis | 18.900 |
| 8 | Huntington disease | 18.520 |
| 21 | Mitochondrial disease | 18.096 |
| 34 | Neurofibromatosis | 17.017 |
| 296 | Biliary atresia | 16.825 |
| 231 | Alpha-1-antitrypsin deficiency | 16.208 |
| 152 | PCDH19-related syndrome | 16.000 |
| 3 | Spinal muscular atrophy | 15.082 |
| 201 | Angelman syndrome | 14.130 |
| 193 | Prader-Willi syndrome | 13.840 |
| 298 | Hereditary pancreatitis | 13.755 |
| 205 | Fragile X syndrome related disease | 13.531 |
| 272 | Fibrodysplasia ossificans progressiva | 13.363 |
| 145 | West syndrome | 13.206 |
| 155 | Acquired aphasia with convulsive disorder | 12.926 |
| 18 | Spinocerebellar degeneration | 12.844 |
| 97 | Ulcerative colitis | 12.381 |
| 98 | Eosinophilic gastro-intestinal disorder | 11.819 |
| 140 | Dorabe syndrome | 11.429 |
| 144 | Lennox-Gastaut syndrome | 11.382 |
| 36 | Epidermolysis bullosa | 11.382 |
| 75 | Cushing disease | 10.912 |
| 156 | Rett syndrome | 10.568 |
| 84 | Sarcoidosis | 10.481 |
| 169 | Menkes disease | 9.000 |
| 170 | Occipital horn syndrome | 9.000 |
| 118 | Myelomeningocele | 6.344 |
| 11 | Myasthenia gravis | 5.954 |
| 113 | Muscular dystrophy | 4.661 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 3.306 |
| 57 | Idiopathic dilated cardiomyopathy | 3.175 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 210 | Single Ventricle | 2.898 |
| 215 | Tetralogy of Fallot | 2.857 |
| 288 | Autoimmune acquired coagulation factor deficiency | 2.857 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.324 |
| 86 | Pulmonary arterial hypertension | 2.118 |
| 337 | Homocystinuria | 2.000 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 1.929 |
| 58 | Hypertrophic cardiomyopathy | 1.875 |
| 78 | Hypopituitarism | 1.360 |
| 212 | Tricuspid atresia | 1.326 |
| 107 | Juvenile idiopathic arthritis | 1.288 |
| 28 | Systemic amyloidosis | 1.204 |
| 167 | Marfan syndrome | 1.125 |
| 65 | Primary immunodeficiency | 1.121 |
| 85 | Idiopathic interstitial pneumonia | 1.100 |
| 251 | Urea cycle disorder | 1.071 |
| 111 | Congenital myopathy | 1.000 |