254. Porphyria Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 85 / Drugs : 67 - (DrugBank : 18) / Drug target genes : 18 - Drug target pathways : 28
Porphyria and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 254 | Porphyria | - |
| 2 | Amyotrophic lateral sclerosis | 10.616 |
| 6 | Parkinson disease | 9.179 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 7.778 |
| 5 | Progressive supranuclear palsy | 4.919 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.947 |
| 8 | Huntington disease | 3.810 |
| 86 | Pulmonary arterial hypertension | 3.739 |
| 98 | Eosinophilic gastro-intestinal disorder | 3.334 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 156 | Rett syndrome | 2.981 |
| 299 | Cystic fibrosis | 2.151 |
| 46 | Malignant rheumatoid arthritis | 2.028 |
| 26 | HTLV-1-associated myelopathy | 1.801 |
| 296 | Biliary atresia | 1.725 |
| 21 | Mitochondrial disease | 1.708 |
| 206 | Fragile X syndrome | 1.657 |
| 53 | Sjogren syndrome | 1.651 |
| 17 | Multiple system atrophy | 1.618 |
| 70 | Spinal stenosis | 1.595 |
| 19 | Lysosomal storage disease | 1.583 |
| 4 | Primary lateral sclerosis | 1.507 |
| 212 | Tricuspid atresia | 1.421 |
| 118 | Myelomeningocele | 1.421 |
| 187 | Kabuki syndrome | 1.404 |
| 169 | Menkes disease | 1.316 |
| 170 | Occipital horn syndrome | 1.316 |
| 11 | Myasthenia gravis | 1.123 |
| 140 | Dorabe syndrome | 1.105 |
| 90 | Retinitis pigmentosa | 1.100 |
| 107 | Juvenile idiopathic arthritis | 1.085 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 1.015 |