Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Alcoholism × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 1. Alcoholism × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
2	Alcoholism 💬	[1] DRD2 💬 Alcoholism × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Alcoholism × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 1. Alcoholism × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
3	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬 Alzheimer disease × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine 💬 Alzheimer disease × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 3. Alzheimer disease × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
4	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬 Alzheimer disease × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine hydrochloride 💬 Alzheimer disease × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 3. Alzheimer disease × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
5	Calcium signaling pathway 💬	[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Calcium signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5 HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Calcium signaling pathway × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 5. Calcium signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
6	Calcium signaling pathway 💬	[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Calcium signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5 HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Calcium signaling pathway × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 5. Calcium signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
7	Calcium signaling pathway 💬	[1] HRH2 💬 Calcium signaling pathway × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine 💬 Calcium signaling pathway × Name Other Names Cimetidine Tagamet	Cimetidine	[2]  2 , 254 💬 7. Calcium signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
8	Calcium signaling pathway 💬	[1] HRH2 💬 Calcium signaling pathway × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine hydrochloride 💬 Calcium signaling pathway × Name Other Names Cimetidine hydrochloride Cimetidine hydrochloride	Cimetidine	[2]  2 , 254 💬 7. Calcium signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
9	cAMP signaling pathway 💬	[3] CHRM1, CHRM2, DRD2 💬 cAMP signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 cAMP signaling pathway × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 9. cAMP signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
10	cAMP signaling pathway 💬	[3] CHRM1, CHRM2, DRD2 💬 cAMP signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 cAMP signaling pathway × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 9. cAMP signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
11	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Chlorpromazine 💬 cGMP-PKG signaling pathway × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 11. cGMP-PKG signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
12	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Chlorpromazine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 11. cGMP-PKG signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
13	Cholinergic synapse 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Cholinergic synapse × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine 💬 Cholinergic synapse × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 13. Cholinergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
14	Cholinergic synapse 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Cholinergic synapse × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine hydrochloride 💬 Cholinergic synapse × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 13. Cholinergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
15	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Cocaine addiction × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 15. Cocaine addiction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
16	Cocaine addiction 💬	[1] DRD2 💬 Cocaine addiction × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Cocaine addiction × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 15. Cocaine addiction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
17	Dopaminergic synapse 💬	[1] DRD2 💬 Dopaminergic synapse × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Dopaminergic synapse × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 17. Dopaminergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
18	Dopaminergic synapse 💬	[1] DRD2 💬 Dopaminergic synapse × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Dopaminergic synapse × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 17. Dopaminergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
19	Gap junction 💬	[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Gap junction × Name Full Name DRD2 D(2) dopamine receptor isoform long HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Gap junction × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 19. Gap junction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
20	Gap junction 💬	[4] DRD2, HTR2A, HTR2B, HTR2C 💬 Gap junction × Name Full Name DRD2 D(2) dopamine receptor isoform long HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Gap junction × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 19. Gap junction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
21	Gastric acid secretion 💬	[1] CHRM3 💬 Gastric acid secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine 💬 Gastric acid secretion × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 21. Gastric acid secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
22	Gastric acid secretion 💬	[1] CHRM3 💬 Gastric acid secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine hydrochloride 💬 Gastric acid secretion × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 21. Gastric acid secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
23	Gastric acid secretion 💬	[1] HRH2 💬 Gastric acid secretion × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine 💬 Gastric acid secretion × Name Other Names Cimetidine Tagamet	Cimetidine	[2]  2 , 254 💬 23. Gastric acid secretion × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
24	Gastric acid secretion 💬	[1] HRH2 💬 Gastric acid secretion × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine hydrochloride 💬 Gastric acid secretion × Name Other Names Cimetidine hydrochloride Cimetidine hydrochloride	Cimetidine	[2]  2 , 254 💬 23. Gastric acid secretion × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
25	Glycine, serine and threonine metabolism 💬	[1] ALAS1 💬 Glycine, serine and threonine metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor	Givosiran 💬 Glycine, serine and threonine metabolism × Name Other Names Givosiran Givosiran	Givosiran	[1] 254 💬 25. Glycine, serine and threonine metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
26	Glycine, serine and threonine metabolism 💬	[1] ALAS1 💬 Glycine, serine and threonine metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor	Givosiran sodium 💬 Glycine, serine and threonine metabolism × Name Other Names Givosiran sodium Givlaari	Givosiran	[1] 254 💬 25. Glycine, serine and threonine metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
27	Glycine, serine and threonine metabolism 💬	[2] ALAS1, ALAS2 💬 Glycine, serine and threonine metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor ALAS2 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform a precursor	Hemin 💬 Glycine, serine and threonine metabolism × Name Other Names Hemin Normosang Panhematin	Hemin	[1] 254 💬 27. Glycine, serine and threonine metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
28	Hormone signaling 💬	[4] ADRA2A, ADRA2B, ADRA2C, DRD2 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Hormone signaling × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 28. Hormone signaling × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
29	Hormone signaling 💬	[4] ADRA2A, ADRA2B, ADRA2C, DRD2 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Hormone signaling × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 28. Hormone signaling × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
30	Hormone signaling 💬	[1] MC1R 💬 Hormone signaling × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide 💬 Hormone signaling × Name Other Names Afamelanotide Scenesse	Afamelanotide	[2] 159, 254 💬 30. Hormone signaling × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
31	Hormone signaling 💬	[1] MC1R 💬 Hormone signaling × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide acetate 💬 Hormone signaling × Name Other Names Afamelanotide acetate Scenesse	Afamelanotide	[2] 159, 254 💬 30. Hormone signaling × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
32	Hormone signaling 💬	[1] MC1R 💬 Hormone signaling × Name Full Name MC1R melanocyte-stimulating hormone receptor	Dersimelagon 💬 Hormone signaling × Name Other Names Dersimelagon Dersimelagon	Dersimelagon	[2] 51, 254 💬 32. Hormone signaling × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
33	Inflammatory mediator regulation of TRP channels 💬	[4] HRH1, HTR2A, HTR2B, HTR2C 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 33. Inflammatory mediator regulation of TRP channels × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
34	Inflammatory mediator regulation of TRP channels 💬	[4] HRH1, HTR2A, HTR2B, HTR2C 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 33. Inflammatory mediator regulation of TRP channels × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
35	Insulin secretion 💬	[1] CHRM3 💬 Insulin secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine 💬 Insulin secretion × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 35. Insulin secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
36	Insulin secretion 💬	[1] CHRM3 💬 Insulin secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine hydrochloride 💬 Insulin secretion × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 35. Insulin secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
37	Melanogenesis 💬	[1] MC1R 💬 Melanogenesis × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide 💬 Melanogenesis × Name Other Names Afamelanotide Scenesse	Afamelanotide	[2] 159, 254 💬 37. Melanogenesis × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
38	Melanogenesis 💬	[1] MC1R 💬 Melanogenesis × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide acetate 💬 Melanogenesis × Name Other Names Afamelanotide acetate Scenesse	Afamelanotide	[2] 159, 254 💬 37. Melanogenesis × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
39	Melanogenesis 💬	[1] MC1R 💬 Melanogenesis × Name Full Name MC1R melanocyte-stimulating hormone receptor	Dersimelagon 💬 Melanogenesis × Name Other Names Dersimelagon Dersimelagon	Dersimelagon	[2] 51, 254 💬 39. Melanogenesis × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
40	Neuroactive ligand signaling 💬	[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 DRD2 D(2) dopamine receptor isoform long HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Neuroactive ligand signaling × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 40. Neuroactive ligand signaling × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
41	Neuroactive ligand signaling 💬	[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 DRD2 D(2) dopamine receptor isoform long HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 40. Neuroactive ligand signaling × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
42	Neuroactive ligand signaling 💬	[1] HRH2 💬 Neuroactive ligand signaling × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine 💬 Neuroactive ligand signaling × Name Other Names Cimetidine Tagamet	Cimetidine	[2]  2 , 254 💬 42. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
43	Neuroactive ligand signaling 💬	[1] HRH2 💬 Neuroactive ligand signaling × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Cimetidine hydrochloride Cimetidine hydrochloride	Cimetidine	[2]  2 , 254 💬 42. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
44	Neuroactive ligand signaling 💬	[1] SLC6A9 💬 Neuroactive ligand signaling × Name Full Name SLC6A9 sodium- and chloride-dependent glycine transporter 1 isoform 2	Bitopertin 💬 Neuroactive ligand signaling × Name Other Names Bitopertin Paliflutine	Bitopertin	[2] 254, 284 💬 44. Neuroactive ligand signaling × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP; 284 Diamond-Blackfan anemia;
45	Neuroactive ligand-receptor interaction 💬	[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 DRD2 D(2) dopamine receptor isoform long HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Neuroactive ligand-receptor interaction × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 45. Neuroactive ligand-receptor interaction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
46	Neuroactive ligand-receptor interaction 💬	[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 DRD2 D(2) dopamine receptor isoform long HRH1 histamine H1 receptor HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 45. Neuroactive ligand-receptor interaction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
47	Neuroactive ligand-receptor interaction 💬	[1] HRH2 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine 💬 Neuroactive ligand-receptor interaction × Name Other Names Cimetidine Tagamet	Cimetidine	[2]  2 , 254 💬 47. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
48	Neuroactive ligand-receptor interaction 💬	[1] HRH2 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH2 histamine H2 receptor isoform 1	Cimetidine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Cimetidine hydrochloride Cimetidine hydrochloride	Cimetidine	[2]  2 , 254 💬 47. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
49	Neuroactive ligand-receptor interaction 💬	[1] MC1R 💬 Neuroactive ligand-receptor interaction × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide 💬 Neuroactive ligand-receptor interaction × Name Other Names Afamelanotide Scenesse	Afamelanotide	[2] 159, 254 💬 49. Neuroactive ligand-receptor interaction × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
50	Neuroactive ligand-receptor interaction 💬	[1] MC1R 💬 Neuroactive ligand-receptor interaction × Name Full Name MC1R melanocyte-stimulating hormone receptor	Afamelanotide acetate 💬 Neuroactive ligand-receptor interaction × Name Other Names Afamelanotide acetate Scenesse	Afamelanotide	[2] 159, 254 💬 49. Neuroactive ligand-receptor interaction × Disease ID Name 159 Xeroderma pigmentosum;XP; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
51	Neuroactive ligand-receptor interaction 💬	[1] MC1R 💬 Neuroactive ligand-receptor interaction × Name Full Name MC1R melanocyte-stimulating hormone receptor	Dersimelagon 💬 Neuroactive ligand-receptor interaction × Name Other Names Dersimelagon Dersimelagon	Dersimelagon	[2] 51, 254 💬 51. Neuroactive ligand-receptor interaction × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
52	Pancreatic secretion 💬	[1] CHRM3 💬 Pancreatic secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine 💬 Pancreatic secretion × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 52. Pancreatic secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
53	Pancreatic secretion 💬	[1] CHRM3 💬 Pancreatic secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine hydrochloride 💬 Pancreatic secretion × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 52. Pancreatic secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
54	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Parkinson disease × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 54. Parkinson disease × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
55	Parkinson disease 💬	[1] DRD2 💬 Parkinson disease × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Parkinson disease × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 54. Parkinson disease × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
56	Pathways of neurodegeneration - multiple diseases 💬	[3] CHRM1, CHRM3, CHRM5 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 56. Pathways of neurodegeneration - multiple diseases × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
57	Pathways of neurodegeneration - multiple diseases 💬	[3] CHRM1, CHRM3, CHRM5 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine hydrochloride 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 56. Pathways of neurodegeneration - multiple diseases × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
58	PI3K-Akt signaling pathway 💬	[2] CHRM1, CHRM2 💬 PI3K-Akt signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2	Chlorpromazine 💬 PI3K-Akt signaling pathway × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 58. PI3K-Akt signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
59	PI3K-Akt signaling pathway 💬	[2] CHRM1, CHRM2 💬 PI3K-Akt signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2	Chlorpromazine hydrochloride 💬 PI3K-Akt signaling pathway × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 58. PI3K-Akt signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
60	Porphyrin metabolism 💬	[1] ALAS1 💬 Porphyrin metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor	Givosiran 💬 Porphyrin metabolism × Name Other Names Givosiran Givosiran	Givosiran	[1] 254 💬 60. Porphyrin metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
61	Porphyrin metabolism 💬	[1] ALAS1 💬 Porphyrin metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor	Givosiran sodium 💬 Porphyrin metabolism × Name Other Names Givosiran sodium Givlaari	Givosiran	[1] 254 💬 60. Porphyrin metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
62	Porphyrin metabolism 💬	[2] ALAS1, ALAS2 💬 Porphyrin metabolism × Name Full Name ALAS1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 precursor ALAS2 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform a precursor	Hemin 💬 Porphyrin metabolism × Name Other Names Hemin Normosang Panhematin	Hemin	[1] 254 💬 62. Porphyrin metabolism × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
63	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine 💬 Rap1 signaling pathway × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 63. Rap1 signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
64	Rap1 signaling pathway 💬	[1] DRD2 💬 Rap1 signaling pathway × Name Full Name DRD2 D(2) dopamine receptor isoform long	Chlorpromazine hydrochloride 💬 Rap1 signaling pathway × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 63. Rap1 signaling pathway × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
65	Regulation of actin cytoskeleton 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Regulation of actin cytoskeleton × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine 💬 Regulation of actin cytoskeleton × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 65. Regulation of actin cytoskeleton × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
66	Regulation of actin cytoskeleton 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Regulation of actin cytoskeleton × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5	Chlorpromazine hydrochloride 💬 Regulation of actin cytoskeleton × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 65. Regulation of actin cytoskeleton × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
67	Salivary secretion 💬	[1] CHRM3 💬 Salivary secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine 💬 Salivary secretion × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 67. Salivary secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
68	Salivary secretion 💬	[1] CHRM3 💬 Salivary secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine hydrochloride 💬 Salivary secretion × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 67. Salivary secretion × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
69	Serotonergic synapse 💬	[3] HTR2A, HTR2B, HTR2C 💬 Serotonergic synapse × Name Full Name HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine 💬 Serotonergic synapse × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 69. Serotonergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
70	Serotonergic synapse 💬	[3] HTR2A, HTR2B, HTR2C 💬 Serotonergic synapse × Name Full Name HTR2A 5-hydroxytryptamine receptor 2A isoform 1 HTR2B 5-hydroxytryptamine receptor 2B isoform 1 HTR2C 5-hydroxytryptamine receptor 2C isoform a precursor	Chlorpromazine hydrochloride 💬 Serotonergic synapse × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 69. Serotonergic synapse × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
71	Synaptic vesicle cycle 💬	[1] SLC6A9 💬 Synaptic vesicle cycle × Name Full Name SLC6A9 sodium- and chloride-dependent glycine transporter 1 isoform 2	Bitopertin 💬 Synaptic vesicle cycle × Name Other Names Bitopertin Paliflutine	Bitopertin	[2] 254, 284 💬 71. Synaptic vesicle cycle × Disease ID Name 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP; 284 Diamond-Blackfan anemia;
72	Taste transduction 💬	[1] CHRM3 💬 Taste transduction × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine 💬 Taste transduction × Name Other Names Chlorpromazine Thorazine	Chlorpromazine	[2] 120, 254 💬 72. Taste transduction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;
73	Taste transduction 💬	[1] CHRM3 💬 Taste transduction × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Chlorpromazine hydrochloride 💬 Taste transduction × Name Other Names Chlorpromazine hydrochloride Sonazine	Chlorpromazine	[2] 120, 254 💬 72. Taste transduction × Disease ID Name 120 Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome; 254 Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;

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