265. Lipodystrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 133 / Drugs : 176 - (DrugBank : 58) / Drug target genes : 30 - Drug target pathways : 102
Lipodystrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 265 | Lipodystrophy | - |
| 46 | Malignant rheumatoid arthritis | 15.884 |
| 96 | Crohn disease | 14.463 |
| 299 | Cystic fibrosis | 13.500 |
| 97 | Ulcerative colitis | 13.159 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 12.836 |
| 78 | Hypopituitarism | 12.084 |
| 2 | Amyotrophic lateral sclerosis | 10.419 |
| 6 | Parkinson disease | 10.370 |
| 236 | Pseudohypoparathyroidism | 8.144 |
| 63 | Idiopathic thrombocytopenic purpura | 6.205 |
| 21 | Mitochondrial disease | 6.139 |
| 246 | Methylmalonic acidemia | 5.068 |
| 65 | Primary immunodeficiency | 4.530 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.943 |
| 84 | Sarcoidosis | 3.761 |
| 49 | Systemic lupus erythematosus | 3.580 |
| 8 | Huntington disease | 2.989 |
| 162 | Pemphigoid | 2.970 |
| 51 | Scleroderma | 2.854 |
| 271 | Ankylosing spondylitis | 2.758 |
| 50 | Dermatomyositis | 2.631 |
| 107 | Juvenile idiopathic arthritis | 2.573 |
| 93 | Primary biliary cholangitis | 2.176 |
| 77 | Growth hormone secreting pituitary adenoma | 2.000 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 195 | Noonan syndrome | 2.000 |
| 263 | Cerebrotendinous xanthomatosis | 2.000 |
| 294 | Congenital diaphragmatic hernia | 1.938 |
| 81 | Congenital adrenal hyperplasia | 1.744 |
| 86 | Pulmonary arterial hypertension | 1.662 |
| 56 | Behcet disease | 1.522 |
| 67 | Polycystic kidney disease | 1.493 |
| 310 | Congenital anomalies syndrome | 1.385 |
| 94 | Primary sclerosing cholangitis | 1.328 |
| 113 | Muscular dystrophy | 1.304 |
| 75 | Cushing disease | 1.287 |
| 301 | Macular dystrophy | 1.231 |
| 225 | Congenital nephrogenic diabetes insipidus | 1.067 |
| 232 | Carney complex | 1.000 |
| 324 | Methylglutaconic aciduria | 1.000 |
| 191 | Werner syndrome | 1.000 |