Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [2] Abacavir; Abacavir sulfate[2] Abacavir sulfate ,
Abacavir 💬 		--[5] 2, 49, 135, 265, 325 💬
2 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
3 Acetylcarnitine [2] Acetyl-l-carnitine; Acetylcarnitine---[3] 2, 97, 265 💬
4 Acipimox [1] Acipimox[1] Acipimox 💬 --[2] 78, 265 💬
5 Amprenavir [1] Amprenavir[1] Amprenavir 💬 --[1] 265 💬
6 Aramchol [1] Aramchol---[2] 94, 265 💬
7 Atazanavir [1] Atazanavir[2] Atazanavir sulfate ,
Atazanavir 💬 		--[1] 265 💬
8 Atorvastatin [3] Atorvastatin; Atorvastatin calcium; Atorvastatina[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Baricitinib [1] Baricitinib[1] Baricitinib 💬 [2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
10 Berberine [2] Berberine; Berberine Chloride[1] Coptis rhizome 💬 --[3] 46, 97, 265 💬
11 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine citrate 💬 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
12 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
13 Cholic Acid [1] CHOLIC ACID[1] Cholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
14 Cyclophosphamide [5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
15 Didanosine [1] Didanosine[1] Didanosine 💬 --[2] 25, 265 💬
16 Diosmin [1] Diosmin[1] Diosmin 💬 --[4] 46, 51, 97, 265 💬
17 Dolutegravir [1] Dolutegravir[2] Dolutegravir ,
Dolutegravir sodium 💬 		--[3] 2, 26, 265 💬
18 Doravirine [1] Doravirine[1] Doravirine 💬 --[1] 265 💬
19 Efavirenz [1] Efavirenz[1] Efavirenz 💬 --[3] 23, 67, 265 💬
20 Emtricitabine [1] Emtricitabine[1] Emtricitabine 💬 --[5] 13, 25, 93, 265, 325 💬
21 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide 💬 --[2] 25, 265 💬
22 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
23 Gemcabene [1] Gemcabene---[2] 79, 265 💬
24 Indinavir [1] Indinavir[3] Indinavir sulfate ,
Indinavir sulfate ethanolate ,
Indinavir 💬 		--[1] 265 💬
25 L-Lactic acid [2] L-Lactic acid; Lactic acid---[1] 265 💬
26 Lactic acid [1] Lactic acid[2] Lactic acid ,
Sodium lactate 💬 		--[3] 46, 265, 299 💬
27 Lamivudine [1] Lamivudine[1] Lamivudine 💬 --[10] 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
28 Leptin [1] Leptin---[2] 6, 265 💬
29 Lopinavir [1] Lopinavir[1] Lopinavir 💬 --[1] 265 💬
30 Mecasermin [1] Mecasermin[2] Mecasermin ,
Mecasermin rinfabate 💬 		[2] GHR,
IGF1R 💬 		[34] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[4] 96, 168, 265, 299 💬
31 Melatonin [1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
32 Metformin [4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
33 Metreleptin [2] METRELEPTIN; R-metHuLeptin[1] Metreleptin 💬 [1] LEPR 💬 [7] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265 💬
34 Mibavademab [1] Mibavademab---[1] 265 💬
35 Nelfinavir [2] Nelfinavir; Nelfinavir mesylate[2] Nelfinavir mesylate ,
Nelfinavir 💬 		--[3] 49, 265, 331 💬
36 Nevirapine [1] Nevirapine[1] Nevirapine 💬 --[1] 265 💬
37 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬 --[4] 6, 46, 79, 265 💬
38 Obeticholic acid [1] Obeticholic Acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
39 Pegvisomant [1] Pegvisomant[1] Pegvisomant 💬 [1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 77, 265 💬
40 Pioglitazone [1] Pioglitazone[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
41 Pravastatin [2] Pravastatin; Pravastatin sodium[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
42 Raltegravir [1] Raltegravir[2] Raltegravir ,
Raltegravir potassium 💬 		--[4] 13, 26, 93, 265 💬
43 Riboflavin [2] Riboflavin; Vitamin B2[1] Riboflavin 💬 --[8] 13, 38, 46, 96, 97, 162, 168, 265 💬
44 Ritonavir [1] Ritonavir[1] Ritonavir 💬 --[3] 2, 86, 265 💬
45 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[2] Rosiglitazone maleate ,
Rosiglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[7] 46, 57, 75, 77, 97, 222, 265 💬
46 Saquinavir [1] Saquinavir[2] Saquinavir ,
Saquinavir mesylate 💬 		--[4] 86, 222, 223, 265 💬
47 Setmelanotide [1] Setmelanotide[2] Setmelanotide ,
Setmelanotide acetate 💬 		[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
48 Simvastatin [2] Simvastatin; Simvastatine[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
49 Stavudine [1] Stavudine[1] Stavudine 💬 --[1] 265 💬
50 Tenofovir [1] Tenofovir[1] Tenofovir 💬 --[8] 2, 6, 13, 25, 26, 93, 265, 325 💬
51 Tenofovir disoproxil [2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate[3] Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--[3] 6, 93, 265 💬
52 Tesamorelin [1] Tesamorelin[2] Tesamorelin ,
Tesamorelin acetate 💬 		[1] GHRHR 💬 [3] Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 265 💬
53 Testosterone [1] Testosterone[1] Testosterone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
54 Thiamine [1] THIAMINE[3] Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[5] 8, 13, 93, 265, 340 💬
55 Tipranavir [1] Tipranavir[2] Tipranavir disodium ,
Tipranavir 💬 		--[1] 265 💬
56 Tirzepatide [1] Tirzepatide[1] Tirzepatide 💬 [2] GIPR,
GLP1R 💬 		[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 67, 96, 97, 193, 233, 265 💬
57 Volanesorsen [1] Volanesorsen[2] Volanesorsen ,
Volanesorsen sodium 💬 		[1] APOC3 💬 [2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬
58 Zidovudine [1] Zidovudine[1] Zidovudine 💬 --[6] 25, 26, 135, 265, 325, 331 💬