274. Osteogenesis Imperfecta Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 108 / Drugs : 113 - (DrugBank : 18) / Drug target genes : 9 - Drug target pathways : 51
Osteogenesis Imperfecta and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 274 | Osteogenesis Imperfecta | - |
| 46 | Malignant rheumatoid arthritis | 7.297 |
| 222 | Primary nephrotic syndrome | 6.260 |
| 65 | Primary immunodeficiency | 6.107 |
| 85 | Idiopathic interstitial pneumonia | 6.078 |
| 51 | Scleroderma | 6.042 |
| 96 | Crohn disease | 5.958 |
| 93 | Primary biliary cholangitis | 5.355 |
| 50 | Dermatomyositis | 5.143 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 19 | Lysosomal storage disease | 4.969 |
| 299 | Cystic fibrosis | 4.857 |
| 95 | Autoimmune hepatitis | 4.789 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 4.675 |
| 151 | Rasmussen encephalitis | 4.464 |
| 55 | Relapsing polychondritis | 4.286 |
| 41 | Giant cell arteritis | 4.242 |
| 66 | IgA nephropathy | 4.200 |
| 107 | Juvenile idiopathic arthritis | 3.971 |
| 113 | Muscular dystrophy | 3.915 |
| 64 | Thrombotic thrombocytopenic purpura | 3.857 |
| 326 | Osteopetrosis | 3.857 |
| 286 | Hereditary sideroblastic anemia | 3.795 |
| 49 | Systemic lupus erythematosus | 3.715 |
| 283 | Acquired pure red cell aplasia | 3.714 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 3.714 |
| 6 | Parkinson disease | 3.630 |
| 284 | Diamond-Blackfan anemia | 3.506 |
| 61 | Autoimmune hemolytic anemia | 3.394 |
| 42 | Polyarteritis nodosa | 3.363 |
| 285 | Fanconi anemia | 3.257 |
| 39 | Toxic epidermal necrolysis | 3.247 |
| 162 | Pemphigoid | 3.195 |
| 56 | Behcet disease | 3.143 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 3.125 |
| 60 | Aplastic anemia | 3.061 |
| 63 | Idiopathic thrombocytopenic purpura | 3.029 |
| 11 | Myasthenia gravis | 3.029 |
| 36 | Epidermolysis bullosa | 2.991 |
| 53 | Sjogren syndrome | 2.945 |
| 38 | Stevens-Johnson syndrome | 2.857 |
| 269 | Pyogenic arthritis | 2.857 |
| 224 | Purpura nephritis | 2.857 |
| 97 | Ulcerative colitis | 2.715 |
| 2 | Amyotrophic lateral sclerosis | 2.691 |
| 160 | Congenital ichthyosis | 2.679 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 2.551 |
| 20 | Adrenoleukodystrophy | 2.516 |
| 227 | Osler disease | 2.484 |
| 40 | Takayasu arteritis | 2.429 |
| 228 | Bronchiolitis obliterans | 2.273 |
| 164 | Oculocutaneous albinism | 2.258 |
| 158 | Tuberous sclerosis | 2.245 |
| 26 | HTLV-1-associated myelopathy | 2.209 |
| 58 | Hypertrophic cardiomyopathy | 2.121 |
| 90 | Retinitis pigmentosa | 2.114 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.037 |
| 28 | Systemic amyloidosis | 2.029 |
| 191 | Werner syndrome | 1.000 |
| 68 | Ossification of the ligamentum flavum | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |