283. Acquired pure red cell aplasia Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 21 / Drugs : 35 - (DrugBank : 20) / Drug target genes : 27 - Drug target pathways : 110
Acquired pure red cell aplasia and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 283 | Acquired pure red cell aplasia | - |
| 13 | Multiple sclerosis | 18.000 |
| 46 | Malignant rheumatoid arthritis | 16.142 |
| 51 | Scleroderma | 14.474 |
| 49 | Systemic lupus erythematosus | 14.472 |
| 96 | Crohn disease | 14.392 |
| 284 | Diamond-Blackfan anemia | 14.205 |
| 60 | Aplastic anemia | 13.393 |
| 65 | Primary immunodeficiency | 12.917 |
| 285 | Fanconi anemia | 12.341 |
| 11 | Myasthenia gravis | 11.857 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 11.624 |
| 19 | Lysosomal storage disease | 11.520 |
| 164 | Oculocutaneous albinism | 10.770 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 10.667 |
| 61 | Autoimmune hemolytic anemia | 9.920 |
| 42 | Polyarteritis nodosa | 9.846 |
| 2 | Amyotrophic lateral sclerosis | 9.662 |
| 66 | IgA nephropathy | 9.371 |
| 85 | Idiopathic interstitial pneumonia | 8.485 |
| 162 | Pemphigoid | 8.148 |
| 228 | Bronchiolitis obliterans | 8.148 |
| 93 | Primary biliary cholangitis | 8.067 |
| 286 | Hereditary sideroblastic anemia | 8.000 |
| 36 | Epidermolysis bullosa | 7.683 |
| 53 | Sjogren syndrome | 7.578 |
| 222 | Primary nephrotic syndrome | 7.494 |
| 28 | Systemic amyloidosis | 7.435 |
| 40 | Takayasu arteritis | 7.333 |
| 97 | Ulcerative colitis | 7.051 |
| 6 | Parkinson disease | 6.973 |
| 41 | Giant cell arteritis | 6.902 |
| 56 | Behcet disease | 6.790 |
| 95 | Autoimmune hepatitis | 6.632 |
| 55 | Relapsing polychondritis | 6.519 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 6.519 |
| 50 | Dermatomyositis | 6.481 |
| 20 | Adrenoleukodystrophy | 6.341 |
| 35 | Pemphigus | 6.341 |
| 224 | Purpura nephritis | 5.926 |
| 64 | Thrombotic thrombocytopenic purpura | 5.778 |
| 326 | Osteopetrosis | 5.778 |
| 63 | Idiopathic thrombocytopenic purpura | 5.400 |
| 107 | Juvenile idiopathic arthritis | 5.279 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 38 | Stevens-Johnson syndrome | 4.719 |
| 26 | HTLV-1-associated myelopathy | 4.491 |
| 151 | Rasmussen encephalitis | 4.398 |
| 39 | Toxic epidermal necrolysis | 4.182 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.111 |
| 43 | Microscopic polyangiitis | 3.714 |
| 274 | Osteogenesis Imperfecta | 3.714 |
| 331 | Idiopathic multicentric castleman disease | 3.688 |
| 269 | Pyogenic arthritis | 3.600 |
| 90 | Retinitis pigmentosa | 3.333 |
| 113 | Muscular dystrophy | 3.230 |
| 44 | Wegener granulomatosis | 3.143 |
| 84 | Sarcoidosis | 3.087 |
| 299 | Cystic fibrosis | 3.034 |
| 256 | Muscle glycogenosis | 2.774 |
| 158 | Tuberous sclerosis | 2.686 |
| 160 | Congenital ichthyosis | 2.392 |
| 94 | Primary sclerosing cholangitis | 2.339 |
| 227 | Osler disease | 2.174 |
| 16 | Crow-Fukase syndrome | 2.000 |
| 58 | Hypertrophic cardiomyopathy | 1.765 |
| 300 | IgG4-related disease | 1.719 |
| 172 | Hypophosphatasia | 1.407 |
| 127 | Frontotemporal lobar degeneration | 1.200 |
| 271 | Ankylosing spondylitis | 1.192 |
| 34 | Neurofibromatosis | 1.032 |
| 86 | Pulmonary arterial hypertension | 1.013 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |