41. Giant cell arteritis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 160 / Drugs : 183 - (DrugBank : 35) / Drug target genes : 32 - Drug target pathways : 125
Giant cell arteritis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 41 | Giant cell arteritis | - |
| 46 | Malignant rheumatoid arthritis | 29.436 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 22.589 |
| 50 | Dermatomyositis | 22.096 |
| 97 | Ulcerative colitis | 21.488 |
| 51 | Scleroderma | 20.280 |
| 96 | Crohn disease | 19.841 |
| 49 | Systemic lupus erythematosus | 18.833 |
| 40 | Takayasu arteritis | 17.065 |
| 65 | Primary immunodeficiency | 16.459 |
| 53 | Sjogren syndrome | 16.279 |
| 107 | Juvenile idiopathic arthritis | 15.152 |
| 84 | Sarcoidosis | 14.043 |
| 56 | Behcet disease | 13.909 |
| 269 | Pyogenic arthritis | 13.463 |
| 162 | Pemphigoid | 13.004 |
| 93 | Primary biliary cholangitis | 12.761 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 12.209 |
| 271 | Ankylosing spondylitis | 12.175 |
| 55 | Relapsing polychondritis | 12.000 |
| 42 | Polyarteritis nodosa | 11.538 |
| 85 | Idiopathic interstitial pneumonia | 11.306 |
| 285 | Fanconi anemia | 10.909 |
| 60 | Aplastic anemia | 10.898 |
| 19 | Lysosomal storage disease | 10.788 |
| 284 | Diamond-Blackfan anemia | 9.777 |
| 11 | Myasthenia gravis | 9.545 |
| 160 | Congenital ichthyosis | 9.455 |
| 164 | Oculocutaneous albinism | 9.258 |
| 44 | Wegener granulomatosis | 8.727 |
| 222 | Primary nephrotic syndrome | 7.789 |
| 228 | Bronchiolitis obliterans | 7.140 |
| 283 | Acquired pure red cell aplasia | 6.902 |
| 95 | Autoimmune hepatitis | 6.699 |
| 28 | Systemic amyloidosis | 6.673 |
| 43 | Microscopic polyangiitis | 6.662 |
| 6 | Parkinson disease | 6.540 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 6.349 |
| 286 | Hereditary sideroblastic anemia | 6.311 |
| 151 | Rasmussen encephalitis | 6.000 |
| 38 | Stevens-Johnson syndrome | 5.172 |
| 66 | IgA nephropathy | 5.022 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 39 | Toxic epidermal necrolysis | 4.994 |
| 326 | Osteopetrosis | 4.970 |
| 299 | Cystic fibrosis | 4.507 |
| 36 | Epidermolysis bullosa | 4.453 |
| 37 | Generalised pustular psoriasis | 4.364 |
| 274 | Osteogenesis Imperfecta | 4.242 |
| 113 | Muscular dystrophy | 4.212 |
| 2 | Amyotrophic lateral sclerosis | 4.136 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.119 |
| 26 | HTLV-1-associated myelopathy | 4.005 |
| 64 | Thrombotic thrombocytopenic purpura | 3.898 |
| 331 | Idiopathic multicentric castleman disease | 3.503 |
| 20 | Adrenoleukodystrophy | 3.240 |
| 227 | Osler disease | 3.163 |
| 224 | Purpura nephritis | 3.055 |
| 61 | Autoimmune hemolytic anemia | 3.029 |
| 58 | Hypertrophic cardiomyopathy | 2.949 |
| 270 | Chronic recurrent multifocal osteomyelitis | 2.828 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.525 |
| 35 | Pemphigus | 2.430 |
| 86 | Pulmonary arterial hypertension | 2.424 |
| 63 | Idiopathic thrombocytopenic purpura | 2.343 |
| 106 | Cryopyrin-associated periodic syndrome | 2.318 |
| 300 | IgG4-related disease | 2.172 |
| 256 | Muscle glycogenosis | 2.041 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 158 | Tuberous sclerosis | 1.932 |
| 34 | Neurofibromatosis | 1.929 |
| 211 | Hypoplastic left heart syndrome | 1.909 |
| 16 | Crow-Fukase syndrome | 1.909 |
| 90 | Retinitis pigmentosa | 1.692 |
| 298 | Hereditary pancreatitis | 1.647 |
| 47 | Buerger disease | 1.636 |
| 266 | Familial mediterranean fever | 1.489 |
| 25 | Progressive multifocal leukoencephalopathy | 1.442 |
| 229 | Autoimmune pulmonary alveolar proteinosis | 1.374 |
| 172 | Hypophosphatasia | 1.374 |
| 235 | Hypoparathyroidism | 1.061 |
| 10 | Charcot-Marie-Tooth disease | 1.017 |
| 15 | Inclusion body myositis | 1.017 |
| 108 | TNF receptor-associated periodic syndrome | 1.000 |
| 267 | Hyper-IgD syndrome | 1.000 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |