63. Idiopathic thrombocytopenic purpura Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 391 / Drugs : 235 - (DrugBank : 50) / Drug target genes : 49 - Drug target pathways : 139
Idiopathic thrombocytopenic purpura and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
63 | Idiopathic thrombocytopenic purpura | - |
13 | Multiple sclerosis/Neuromyelitis optica | 25.292 |
299 | Cystic fibrosis | 24.470 |
46 | Malignant rheumatoid arthritis | 19.023 |
236 | Pseudohypoparathyroidism | 16.920 |
226 | Interstitial cystitis with Hunners ulcer | 15.797 |
246 | Methylmalonic acidemia | 15.393 |
96 | Crohn disease | 14.400 |
2 | Amyotrophic lateral sclerosis | 14.363 |
6 | Parkinson disease | 11.051 |
97 | Ulcerative colitis | 10.443 |
64 | Thrombotic thrombocytopenic purpura | 9.800 |
60 | Aplastic anemia | 9.617 |
49 | Systemic lupus erythematosus | 8.905 |
65 | Primary immunodeficiency | 7.522 |
61 | Autoimmune hemolytic anemia | 7.424 |
51 | Scleroderma | 7.149 |
162 | Pemphigoid | 6.400 |
66 | IgA nephropathy | 6.217 |
39 | Toxic epidermal necrolysis | 6.206 |
265 | Lipodystrophy | 6.205 |
56 | Behcet disease | 6.133 |
62 | Paroxysmal nocturnal hemoglobinuria | 5.926 |
285 | Fanconi anemia | 5.736 |
283 | Acquired pure red cell aplasia | 5.400 |
107 | Juvenile idiopathic arthritis | 5.231 |
53 | Sjogren syndrome | 5.120 |
302 | Leber hereditary optic neuropathy | 5.000 |
222 | Primary nephrotic syndrome | 4.931 |
78 | Hypopituitarism | 4.767 |
21 | Mitochondrial disease | 4.634 |
50 | Dermatomyositis | 4.594 |
160 | Congenital ichthyosis | 4.346 |
85 | Idiopathic interstitial pneumonia | 4.267 |
151 | Rasmussen encephalitis | 4.259 |
224 | Purpura nephritis | 3.847 |
228 | Bronchiolitis obliterans | 3.764 |
113 | Muscular dystrophy | 3.540 |
55 | Relapsing polychondritis | 3.400 |
45 | Eosinophilic granulomatosis with Polyangiitis | 3.388 |
271 | Ankylosing spondylitis | 3.380 |
286 | Hereditary sideroblastic anemia | 3.333 |
294 | Congenital diaphragmatic hernia | 3.271 |
94 | Primary sclerosing cholangitis | 3.267 |
36 | Epidermolysis bullosa | 3.122 |
274 | Osteogenesis Imperfecta | 3.029 |
284 | Diamond-Blackfan anemia | 2.970 |
93 | Primary biliary cholangitis | 2.926 |
38 | Stevens-Johnson syndrome | 2.880 |
269 | Pyogenic arthritis | 2.880 |
26 | HTLV-1-associated myelopathy | 2.807 |
83 | Addison disease | 2.785 |
28 | Systemic amyloidosis | 2.782 |
42 | Polyarteritis nodosa | 2.680 |
11 | Myasthenia gravis | 2.592 |
58 | Hypertrophic cardiomyopathy | 2.519 |
90 | Retinitis pigmentosa | 2.496 |
95 | Autoimmune hepatitis | 2.442 |
234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.407 |
41 | Giant cell arteritis | 2.343 |
164 | Oculocutaneous albinism | 2.306 |
71 | Idiopathic osteonecrosis of the femoral head | 2.300 |
158 | Tuberous sclerosis | 2.271 |
19 | Lysosomal storage disease | 2.185 |
227 | Osler disease | 2.157 |
84 | Sarcoidosis | 2.064 |
40 | Takayasu arteritis | 2.048 |
282 | Congenital dyserythropoietic anemia | 2.000 |
86 | Pulmonary arterial hypertension | 1.948 |
326 | Osteopetrosis | 1.944 |
16 | Crow-Fukase syndrome | 1.880 |
76 | Pituitary gonadotropin secretion hyperthyroidism | 1.600 |
20 | Adrenoleukodystrophy | 1.566 |
331 | Idiopathic multicentric castleman disease | 1.272 |
8 | Huntington disease | 1.171 |
288 | Autoimmune acquired coagulation factor deficiency | 1.165 |
98 | Eosinophilic gastrointestinal disease | 1.098 |
35 | Pemphigus | 1.018 |
137 | Focal cortical dysplasia | 1.000 |
192 | Cockayne syndrome | 1.000 |
277 | Lymphangiomatosis | 1.000 |
281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
52 | Mixed connective tissue disease | 1.000 |
220 | Rapidly progressive glomerulonephritis | 1.000 |
30 | Distal myopathy | 1.000 |