63. Idiopathic thrombocytopenic purpura Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 868 / Drugs : 544 - (DrugBank : 96) / Drug target genes : 82 - Drug target pathways : 195
Idiopathic thrombocytopenic purpura and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 63 | Idiopathic thrombocytopenic purpura | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 25.292 |
| 299 | Cystic fibrosis | 24.470 |
| 46 | Malignant rheumatoid arthritis | 19.023 |
| 236 | Pseudohypoparathyroidism | 16.920 |
| 226 | Interstitial cystitis with Hunners ulcer | 15.797 |
| 246 | Methylmalonic acidemia | 15.393 |
| 96 | Crohn disease | 14.400 |
| 2 | Amyotrophic lateral sclerosis | 14.363 |
| 6 | Parkinson disease | 11.051 |
| 97 | Ulcerative colitis | 10.443 |
| 64 | Thrombotic thrombocytopenic purpura | 9.800 |
| 60 | Aplastic anemia | 9.617 |
| 49 | Systemic lupus erythematosus | 8.905 |
| 65 | Primary immunodeficiency | 7.522 |
| 61 | Autoimmune hemolytic anemia | 7.424 |
| 51 | Scleroderma | 7.149 |
| 162 | Pemphigoid | 6.400 |
| 66 | IgA nephropathy | 6.217 |
| 39 | Toxic epidermal necrolysis | 6.206 |
| 265 | Lipodystrophy | 6.205 |
| 56 | Behcet disease | 6.133 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 5.926 |
| 285 | Fanconi anemia | 5.736 |
| 283 | Acquired pure red cell aplasia | 5.400 |
| 107 | Juvenile idiopathic arthritis | 5.231 |
| 53 | Sjogren syndrome | 5.120 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 222 | Primary nephrotic syndrome | 4.931 |
| 78 | Hypopituitarism | 4.767 |
| 21 | Mitochondrial disease | 4.634 |
| 50 | Dermatomyositis | 4.594 |
| 160 | Congenital ichthyosis | 4.346 |
| 85 | Idiopathic interstitial pneumonia | 4.267 |
| 151 | Rasmussen encephalitis | 4.259 |
| 224 | Purpura nephritis | 3.847 |
| 228 | Bronchiolitis obliterans | 3.764 |
| 113 | Muscular dystrophy | 3.540 |
| 55 | Relapsing polychondritis | 3.400 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 3.388 |
| 271 | Ankylosing spondylitis | 3.380 |
| 286 | Hereditary sideroblastic anemia | 3.333 |
| 294 | Congenital diaphragmatic hernia | 3.271 |
| 94 | Primary sclerosing cholangitis | 3.267 |
| 36 | Epidermolysis bullosa | 3.122 |
| 274 | Osteogenesis Imperfecta | 3.029 |
| 284 | Diamond-Blackfan anemia | 2.970 |
| 93 | Primary biliary cholangitis | 2.926 |
| 38 | Stevens-Johnson syndrome | 2.880 |
| 269 | Pyogenic arthritis | 2.880 |
| 26 | HTLV-1-associated myelopathy | 2.807 |
| 83 | Addison disease | 2.785 |
| 28 | Systemic amyloidosis | 2.782 |
| 42 | Polyarteritis nodosa | 2.680 |
| 11 | Myasthenia gravis | 2.592 |
| 58 | Hypertrophic cardiomyopathy | 2.519 |
| 90 | Retinitis pigmentosa | 2.496 |
| 95 | Autoimmune hepatitis | 2.442 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.407 |
| 41 | Giant cell arteritis | 2.343 |
| 164 | Oculocutaneous albinism | 2.306 |
| 71 | Idiopathic osteonecrosis of the femoral head | 2.300 |
| 158 | Tuberous sclerosis | 2.271 |
| 19 | Lysosomal storage disease | 2.185 |
| 227 | Osler disease | 2.157 |
| 84 | Sarcoidosis | 2.064 |
| 40 | Takayasu arteritis | 2.048 |
| 282 | Congenital dyserythropoietic anemia | 2.000 |
| 86 | Pulmonary arterial hypertension | 1.948 |
| 326 | Osteopetrosis | 1.944 |
| 16 | Crow-Fukase syndrome | 1.880 |
| 76 | Pituitary gonadotropin secretion hyperthyroidism | 1.600 |
| 20 | Adrenoleukodystrophy | 1.566 |
| 331 | Idiopathic multicentric castleman disease | 1.272 |
| 8 | Huntington disease | 1.171 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.165 |
| 98 | Eosinophilic gastro-intestinal disorder | 1.098 |
| 35 | Pemphigus | 1.018 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |