Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Alemtuzumab [1] Alemtuzumab[1] Alemtuzumab 💬 --[20] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
2 Amifostine [2] Amifostine; Amifostine trihydrate[1] Amifostine 💬 --[2] 28, 63 💬
3 Aminophylline [1] Aminophylline[2] Aminophylline ,
Aminophylline dihydrate 💬
[18] ADORA1,
ADORA2B,
PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63 💬
4 Amoxicillin [2] Amoxicilina; Amoxicillin[3] Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬
--[6] 19, 46, 63, 96, 97, 299 💬
5 Atorvastatin [2] Atorvastatin; Atorvastatin calcium[2] Atorvastatin calcium ,
Atorvastatin 💬
[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
6 Avatrombopag [2] Avatrombopag; Avatrombopag maleate[2] Avatrombopag ,
Avatrombopag maleate 💬
[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
7 Azathioprine [2] Azathioprine; Azatioprina[2] Azathioprine ,
Azathioprine sodium 💬
--[22] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
8 Belimumab [1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[14] 11, 13, 43, 44, 46, 48, 49, 51, 53, 63, 66, 95, 222, 296 💬
9 Bevifimod [1] Staphylococcal protein A---[1] 63 💬
10 Blisibimod [1] Blisibimod[1] Blisibimod 💬 --[5] 43, 44, 49, 63, 66 💬
11 Bortezomib [1] Bortezomib[1] Bortezomib 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[18] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
12 Caplacizumab [1] Caplacizumab[1] Caplacizumab 💬 [1] VWF 💬 [8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬[2] 63, 64 💬
13 Clarithromycin [1] Clarithromycin[1] Clarithromycin 💬 --[9] 6, 13, 46, 63, 84, 96, 97, 228, 299 💬
14 Cyclosporine [6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[1] Cyclosporine 💬 [5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[42] 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Danazol [1] Danazol[1] Danazol 💬 [3] AR,
ESR1,
PGR 💬
[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
16 Daratumumab [1] Daratumumab[1] Daratumumab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[10] 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
17 Decitabine [1] Decitabine[1] Decitabine 💬 [3] DNMT1,
DNMT3A,
DNMT3B 💬
[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬[3] 13, 60, 63 💬
18 Dexamethasone [2] Dexamethasone; Dexamethasone sodium phosphate[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
19 Dexamethasone palmitate [1] Dexamethasone palmitate[1] Dexamethasone palmitate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 63 💬
20 Efgartigimod alfa [1] Efgartigimod alfa[1] Efgartigimod alfa 💬 --[7] 11, 13, 14, 35, 53, 63, 162 💬
21 Eltrombopag [2] Eltrombopag; Eltrombopag olamine[2] Eltrombopag olamine ,
Eltrombopag choline 💬
[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
22 Ethanolamine [1] Ethanolamine[1] Monoethanolamine 💬 --[2] 63, 279 💬
23 Fecal microbiota [1] Fecal microbiota---[12] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 271 💬
24 Fostamatinib [2] Fostamatinib; Fostamatinib disodium[2] Fostamatinib ,
Fostamatinib disodium 💬
[1] SYK 💬 [17] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[5] 46, 49, 61, 63, 66 💬
25 Glycyrrhiza glabra [1] Glycyrrhiza---[3] 53, 63, 97 💬
26 Hetrombopag [1] Hetrombopag---[2] 60, 63 💬
27 Human immunoglobulin G [6] Human immunoglobulin G; Human normal immunoglobulin; Immune globulin; Immunoglobulin; Immunoglobulin G; Intravenous immunoglobulin[1] Globulin, immune 💬 --[9] 11, 13, 14, 43, 45, 50, 51, 63, 65 💬
28 Hydroxychloroquine [2] Hydroxychloroquine; Hydroxychloroquine sulfate[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬
--[27] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
29 Ianalumab [1] Ianalumab[1] Ianalumab 💬 [1] TNFRSF13C 💬 [5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[8] 35, 46, 49, 51, 53, 61, 63, 95 💬
30 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬 [2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[6] 63, 71, 85, 166, 222, 299 💬
31 Lusutrombopag [1] Lusutrombopag[1] Lusutrombopag 💬 [1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
32 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[2] Methylprednisolone ,
Methylprednisolone acetate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
33 Metronidazole [2] Metronidazol; Metronidazole[2] Metronidazole ,
Metronidazole hydrochloride 💬
--[7] 46, 51, 63, 94, 96, 97, 291 💬
34 Mezagitamab [1] Mezagitamab[1] Mezagitamab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 63, 66 💬
35 Montelukast [2] Montelukast; Montelukast sodium[2] Montelukast sodium ,
Montelukast 💬
[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[9] 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
36 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬
[2] IMPDH,
IMPDH 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
37 Mycophenolic acid [5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] Mycophenolate sodium ,
Mycophenolic acid 💬
[2] IMPDH,
IMPDH 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
38 Natural Killer Cell [1] NK cells---[3] 26, 49, 63 💬
39 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[20] 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
40 Obinutuzumab [1] Obinutuzumab[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[5] 43, 44, 49, 63, 222 💬
41 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63 💬
42 Povetacicept [1] Povetacicept[1] Povetacicept 💬 [1] TNFRSF13B 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬[3] 61, 63, 222 💬
43 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[41] 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
44 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
45 Prednisone acetate [2] Cortancyl; Prednisone acetate[1] Prednisone acetate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 40, 41, 46, 49, 63, 162, 222, 224 💬
46 PRTX-100 [1] PRTX-100---[2] 46, 63 💬
47 Recombinant Human Thrombopoietin [2] Recombinant human thrombopoietin; Rhtpo---[2] 60, 63 💬
48 Rilzabrutinib [1] Rilzabrutinib[1] Rilzabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 35, 61, 63, 222, 300 💬
49 Rituximab [1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
50 Romiplostim [1] Romiplostim[1] Romiplostim 💬 [1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65 💬
51 Rozanolixizumab [2] Rozanolixizumab; UCB7665[1] Rozanolixizumab 💬 --[3] 11, 14, 63 💬
52 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
53 Telitacicept [1] Telitacicept---[11] 11, 13, 46, 48, 49, 51, 53, 63, 66, 222, 300 💬
54 Teriflunomide [1] Teriflunomide[1] Teriflunomide 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[4] 13, 25, 26, 63 💬
55 Thrombopoietin [1] Thrombopoietin---[3] 47, 61, 63 💬
56 Toralizumab [1] ANTI-CD40L[1] Toralizumab 💬 [1] TNFSF5 💬 [14] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬[1] 63 💬
57 Tretinoin [3] Atra; Tretinoin; Tretinoina[1] Tretinoin 💬 [3] PML,
RARA,
RARB 💬
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231 💬
58 Veltuzumab [1] Veltuzumab[1] Veltuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[2] 46, 63 💬
59 Vinblastine [2] Vinblastine; Vinblastine sulfate[2] Vinblastine sulfate ,
Vinblastine 💬
[9] TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB 💬
[11] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[3] 34, 63, 65 💬
60 Von Willebrand factor human [3] Factor VON willebrand; Human VON willebrand factor; VON willebrand factor---[2] 63, 288 💬
61 Vonoprazan [1] Vonoprazan[1] Vonoprazan 💬 [2] ATP4A,
ATP4B 💬
[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[3] 63, 97, 98 💬
62 Water [1] Water[1] Water 💬 --[28] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 64, 66, 67, 72, 85, 96, 97, 206, 225, 226, 230, 274, 278, 299 💬
63 Zanubrutinib [1] Zanubrutinib[1] Zanubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[6] 13, 61, 63, 222, 300, 331 💬
64 ZUBERITAMAB [1] Zuberitamab---[2] 63, 222 💬