Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Otis Clapp Valihist)		5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetic acid
(Synonym: Treagan Otic)		1件: Acetic acid1件: D00010 --1件: 97
3 Allantoin
(Synonym: Inflammation OTC Radiation Relief)		1件: ALLANTOIN1件: D00121 --1件: 36
4 Aloe vera leaf
(Synonym: C Ottways Lax Tab)		3件: Aloe; Aloe vera; Aloe vera gel---3件: 53, 97, 226
5 Apremilast
(Synonym: Otezla)		2件: APREMILAST; Otezla1件: D08860 (Name: Otezla (TN))4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
6 Betamethasone
(Synonym: Betamycin Ophthalmic/otic Solution)		1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
7 Calcium carbonate
(Synonym: Relief OTC antacid)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
8 Capsaicin
(Synonym: Pallerix OTC BIOfrequency Chip)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬5件: 2, 6, 19, 86, 226
9 Chlorpheniramine
(Synonym: Otis Clapp Valihist)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
10 Ciprofloxacin
(Synonym: Otovel)		2件: Ciprofloxacin; Ciprofloxacin hydrochloride2件: D00186 (Name: Otiprio (TN)),
D02216 (Name: CIPROFLOXACIN OTIC)		--5件: 2, 60, 96, 97, 299
11 Ethanol
(Synonym: hand sanitizer OTC)		3件: Alcohol; Ethanol; Prednisone4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
12 Fluocinolone acetonide
(Synonym: Flac Otic Oil)		2件: Fluocinolone Acetonide; Iluvien1件: D01825 (Name: FLAC OTIC OIL)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
13 Gentamicin
(Synonym: Betamycin Ophthalmic/otic Solution)		2件: Gentamicin; Gentamicin Sulfate2件: D01063 ,
D08013 		--3件: 36, 113, 299
14 Ginger
(Synonym: C Ottways Lax Tab)		1件: Ginger1件: D06744 --2件: 46, 271
15 Glycyrrhiza glabra
(Synonym: C Ottways Lax Tab)		3件: Glycyrrhiza; Glycyrrhiza glabra; GLYCYRRHIZA GLABRA ROOT---2件: 53, 97
16 Hydrocortisone
(Synonym: Oti Rx)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
17 Hydrocortisone acetate
(Synonym: Otizol HC Liq)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
18 Ibuprofen
(Synonym: Otis Clapp Ultraprin)		2件: Ibuprofen; IBUPROFEN 200MG4件: D00126 ,
D01122 ,
D04490 ,
D06606 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
19 Lidocaine
(Synonym: Otizol HC Liq)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
20 Methotrexate
(Synonym: Otrexup)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate2件: D00142 (Name: Otrexup (TN)),
D02115 		2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
21 Neomycin
(Synonym: Synalar Bi-otic Solution)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
22 Omeprazole
(Synonym: Prilosec OTC)		5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM4件: D00455 ,
D01207 ,
D05259 (Name: Prilosec OTC (TN)),
D05261 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
23 Otelixizumab 1件: Otelixizumab1件: D08959 (Name: Otelixizumab)3件: CD3D,
CD3E,
CD3G 💬		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46
24 Otilimab 1件: Otilimab1件: D11343 (Name: Otilimab)1件: CSF2 💬16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬2件: 46, 256
25 Phenylephrine
(Synonym: Otis Clapp Mygrex)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
26 Senna leaf
(Synonym: C Ottways Lax Tab)		1件: Senna1件: D06751 --1件: 291
27 Sodium bicarbonate
(Synonym: Zegerid OTC)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
28 Zinc acetate
(Synonym: Otozin)		2件: Wilzin; Zinc acetate1件: D06408 --2件: 171, 299