Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Tabalumab 1件: Tabalumab1件: D10083 1件: TNFSF13B 💬4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬2件: 46, 49
2 Tacrine 0件: 2件: D02068 ,
D08555 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 46, 271, 299
3 Tacrolimus 2件: Prograf; Tacrolimus2件: D00107 ,
D08556 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
4 Tadalafil 4件: Adcirca; CIALIS; TADALAFIL; TADALAFILO1件: D02008 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
5 Tadekinig alfa 1件: TADEKINIG ALFA---1件: 65
6 Tafamidis 2件: Tafamidis; Vyndaqel1件: D09673 1件: TTR 💬1件: Thyroid hormone synthesis 💬1件: 28
7 Tafluprost 1件: TAFLUPROST1件: D06274 1件: PTGFR 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 299
8 TAK-475 1件: TAK-475---1件: 79
9 TAK-715 1件: TAK-715---1件: 46
10 TAK-831 1件: TAK-831---1件: 18
11 Taladegib 1件: Taladegib1件: D10671 1件: SMO 💬5件: Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬1件: 85
12 Talampanel 1件: Talampanel1件: D02696 4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬2件: 2, 6
13 Taliglucerase alfa 3件: Elelyso; PrGCD; TALIGLUCERASE ALFA1件: D09675 1件: GBA 💬4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19
14 Talniflumate 1件: Talniflumate1件: D02701 --1件: 299
15 Tamibarotene 1件: Tamibarotene1件: D01418 1件: RARA 💬5件: Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬2件: 26, 96
16 Tamoxifen 2件: Tamoxifen; TAMOXIFEN CITRATE2件: D00966 ,
D08559 		2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 2, 86, 113, 227
17 Tanezumab 1件: Tanezumab1件: D09387 1件: NGF 💬9件: Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 226, 298
18 Tarenflurbil 2件: FLURBIPROFEN; Tarenflurbil1件: D09010 4件: APH1A,
NCSTN,
PSEN1,
PSENEN 💬		6件: Alzheimer disease, Human papillomavirus infection, Neurotrophin signaling pathway, Notch signaling pathway, Pathways of neurodegeneration - multiple diseases, Wnt signaling pathway 💬1件: 13
19 Tasimelteon 1件: Tasimelteon1件: D09388 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬1件: 202
20 Taurine 1件: Taurine1件: D00047 --2件: 13, 337
21 Tauroursodeoxycholic acid 2件: TAUROURSODEOXYCHOLIC ACID; TUDCA1件: D11836 --4件: 2, 13, 93, 299
22 Tavapadon 2件: PF-06649751; TAVAPADON1件: D11431 2件: DRD1,
DRD5 💬		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6
23 Tazobactam 1件: TAZOBACTAM1件: D00660 --1件: 299
24 TD-139 0件: ---1件: 85
25 Tea leaf 1件: Tea leaf---3件: 17, 46, 271
26 Technetium Tc-99m 1件: Technetium Tc 99M---2件: 46, 98
27 Technetium Tc-99m exametazime 1件: Ceretec---1件: 6
28 Technetium Tc-99m tilmanocept 1件: Technetium Tc 99m Tilmanocept---1件: 46
29 Tedizolid 1件: Tedizolid1件: D09685 --1件: 299
30 Teduglutide 1件: Teduglutide1件: D06053 1件: GLP2R 💬1件: Neuroactive ligand-receptor interaction 💬1件: 96
31 Tefibazumab 1件: Tefibazumab1件: D06054 --1件: 299
32 Tegafur 0件: 1件: D01244 1件: TYMS 💬4件: Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism 💬1件: 46
33 Teicoplanin 1件: Teicoplanin1件: D02142 --2件: 70, 299
34 Telavancin 1件: Telavancin---1件: 299
35 Telbivudine 0件: 1件: D06675 --1件: 65
36 Telmisartan 1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
37 Telotristat 1件: Telotristat1件: D09973 2件: TPH1,
TPH2 💬		4件: Folate biosynthesis, Metabolic pathways, Serotonergic synapse, Tryptophan metabolism 💬1件: 97
38 Temelimab 1件: TEMELIMAB---1件: 13
39 Temozolomide 1件: Temozolomide1件: D06067 --1件: 34
40 Temsirolimus 1件: Temsirolimus1件: D06068 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬4件: 13, 34, 89, 331
41 Tenamfetamine 0件: ---1件: 46
42 Tenofovir 1件: Tenofovir1件: D06074 --6件: 2, 13, 25, 93, 265, 325
43 Tenofovir alafenamide 1件: Tenofovir alafenamide1件: D10428 --2件: 2, 13
44 Tenofovir disoproxil 4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA1件: D01982 --2件: 93, 265
45 Teprotumumab 1件: TEPEZZA1件: D09680 1件: IGF1R 💬29件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬1件: 51
46 Terazosin 1件: Terazosin2件: D00610 ,
D08569 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
47 Terbinafine 1件: Terbinafine2件: D02219 ,
D02375 		--3件: 96, 97, 271
48 Terbutaline 1件: Terbutaline2件: D00688 ,
D08570 		1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 118
49 Terguride 1件: Terguride1件: D01348 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 51, 86
50 Teriflunomide 2件: AUBAGIO; TERIFLUNOMIDE1件: D10172 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬3件: 13, 25, 26
51 Teriparatide 4件: Forsteo; Forteo; PTH 1-34; Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬7件: 46, 65, 68, 70, 71, 235, 274
52 Terlipressin 1件: TERLIPRESSIN1件: D06672 3件: AVPR1A,
AVPR1B,
AVPR2 💬		5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 299
53 Tesamorelin 2件: GHRH; Tesamorelin1件: D06655 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
54 Tesevatinib 1件: Tesevatinib1件: D11772 5件: EGFR,
EPHB4,
ERBB2,
FLT4,
KDR 💬		53件: Adherens junction, Axon guidance, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, VEGF signaling pathway 💬1件: 67
55 Tesofensine 1件: TESOFENSINE---2件: 6, 193
56 Testosterone 1件: Testosterone6件: D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087 		1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
57 Testosterone decanoate 1件: Testosterone decanoate1件: D08573 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
58 Testosterone enanthate 2件: Testosterone Enanthate; Xyosted1件: D00958 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 13, 113
59 Testosterone isocaproate 1件: Testosterone isocaproate---1件: 113
60 Testosterone phenylpropionate 1件: Testosterone phenylpropionate1件: D08574 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
61 Testosterone propionate 1件: Testosterone propionate1件: D00959 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
62 Testosterone undecanoate 1件: Testosterone undecanoate1件: D06087 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 13, 60
63 Tetomilast 1件: Tetomilast---2件: 96, 97
64 Tetrabenazine 2件: Tetrabenazine; Xenazine1件: D08575 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
65 Tetracosactide 4件: Cosyntropin; SYNACTHEN DEPOT; TETRACOSACTIDE; Tetracosactrin1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222
66 Tetracycline 2件: Tetracyclin; Tetracycline1件: D00201 --5件: 13, 36, 46, 53, 97
67 Tetradecyl hydrogen sulfate (ester) 0件: ---1件: 279
68 Tetrandrine 1件: Tetrandrine---2件: 46, 85
69 Tetrathiomolybdate 1件: Tetrathiomolybdate---3件: 85, 93, 171
70 Tezacaftor 5件: Kaftrio; Symdeko; Symkevi; TEZACAFTOR; Trikafta1件: D11041 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
71 Tezosentan 1件: Tezosentan---1件: 86
72 Thalidomide 1件: Thalidomide1件: D00754 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
73 Theophylline 1件: Theophylline5件: D00371 ,
D01712 ,
D02017 ,
D06103 ,
D06104 		19件: ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		24件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299
74 Thiamine 2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
75 Thiotepa 1件: Thiotepa1件: D00583 --12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
76 Threonine 1件: Threonine1件: D00041 --3件: 86, 96, 97
77 Thrombin 1件: Thrombin1件: D00090 --2件: 86, 88
78 Thrombomodulin Alfa 1件: Thrombomodulin Alfa1件: D06410 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬1件: 85
79 Thrombopoietin 1件: Thrombopoietin---3件: 47, 60, 63
80 Thymalfasin 1件: THYMALFASIN1件: D06116 --2件: 65, 299
81 Thymidine 1件: Thymidine---1件: 215
82 Thymidine monophosphate 0件: ---1件: 299
83 Thymol 1件: Thymol1件: D01039 --1件: 13
84 Thymosin beta-4 1件: Thymosin Beta 4---2件: 36, 53
85 Thyroid, porcine 1件: Thyroid---1件: 78
86 Thyrotropin 1件: Thyrotropin---1件: 80
87 Tiapride 0件: 1件: D08590 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 8
88 Tibulizumab 1件: Tibulizumab1件: D11127 2件: IL17A,
TNFSF13B 💬		8件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis, Th17 cell differentiation 💬1件: 53
89 Ticagrelor 1件: Ticagrelor1件: D09017 1件: P2RY12 💬1件: Platelet activation 💬3件: 36, 46, 85
90 Ticarcillin 1件: Ticarcillin1件: D08593 --1件: 299
91 Tick-borne encephalitis vaccine (whole virus, inactivated) 0件: ---1件: 46
92 Tideglusib 1件: Tideglusib---2件: 5, 113
93 Tigecycline 1件: Tigecycline1件: D01079 --1件: 93
94 Tilactase 1件: Beta-Galactosidase1件: D03348 --1件: 19
95 Tilarginine 1件: NG-Monomethyl-L-arginine---1件: 67
96 Tildrakizumab 2件: Ilumetri; Tildrakizumab1件: D10400 1件: IL23A 💬9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬2件: 162, 271
97 Tilmanocept 2件: Lymphoseek; TILMANOCEPT---1件: 46
98 Timolol 2件: Timolol; TIMOLOL MALEATE3件: D00378 ,
D00603 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
99 Timrepigene emparvovec 1件: Timrepigene emparvovec---1件: 90
100 Tioguanine 0件: 2件: D06109 ,
D08603 		1件: HPRT1 💬3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬2件: 13, 37
101 Tiotropium 3件: Spiriva; Spiriva Respimat; Tiotropium---3件: 55, 85, 299
102 Tipelukast 1件: Tipelukast1件: D06659 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 85
103 Tipifarnib 1件: Tipifarnib1件: D03720 2件: FNTA,
FNTB 💬		1件: Terpenoid backbone biosynthesis 💬1件: 34
104 Tipranavir 1件: Tipranavir2件: D03843 ,
D08605 		--1件: 265
105 Tirabrutinib 1件: Tirabrutinib---3件: 35, 46, 53
106 Tirasemtiv 1件: Tirasemtiv1件: D10327 --1件: 2
107 Tiratricol 1件: Tiratricol1件: D07214 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬2件: 78, 139
108 Titanium 2件: Titan; Titanium---3件: 46, 69, 70
109 Tizanidine 1件: Tizanidine2件: D00776 ,
D08611 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 13
110 TMP 1件: TMP---1件: 299
111 Tobacco leaf 1件: Tobacco---1件: 299
112 Tobramycin 9件: Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum2件: D00063 ,
D02542 		--1件: 299
113 Tocilizumab 3件: Actemra; RoActemra; TOCILIZUMAB1件: D02596 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
114 Tocofersolan 1件: VEDROP1件: D06174 --1件: 299
115 Tocopherol 2件: Tocoferol; Tocopherol1件: D02332 --6件: 13, 49, 90, 206, 257, 298
116 Tocotrienol 1件: Tocotrienol---3件: 21, 156, 299
117 Tofacitinib 4件: Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR1件: D09970 4件: JAK1,
JAK2,
JAK3,
TYK2 💬		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
118 Tofersen 1件: Tofersen1件: D11811 1件: SOD1 💬8件: Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬1件: 2
119 Tolcapone 3件: Tasmar; Tolcapon; TOLCAPONE1件: D00786 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127
120 Tolfenamic acid 1件: Tolfenamic Acid1件: D01183 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
121 Tolperisone 1件: Tolperisone1件: D08617 --1件: 13
122 Tolterodine 1件: Tolterodine2件: D00646 ,
D01148 		1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53
123 Tolvaptan 3件: Jinarc; Samsca; Tolvaptan1件: D01213 1件: AVPR2 💬3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬3件: 67, 72, 225
124 TOP-1288 0件: ---1件: 97
125 Topiramate 2件: TOPAMAX; Topiramate1件: D00537 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
126 Topotecan 1件: Topotecan2件: D02168 ,
D08618 		1件: TOP1 💬-1件: 25
127 Topramezone 0件: ---8件: 6, 13, 46, 50, 53, 96, 97, 299
128 Toralizumab 1件: Anti-CD40L1件: D06193 1件: CD40LG 💬14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63
129 Tozadenant 1件: TOZADENANT1件: D10174 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
130 Trabectedin 2件: TRABECTEDINA; Yondelis1件: D06199 --1件: 159
131 Tralokinumab 1件: Tralokinumab1件: D09979 1件: IL13 💬8件: Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬2件: 85, 97
132 Tramadol 2件: Tramadol; Ultracet2件: D01355 ,
D08623 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
133 Trametinib 2件: Mekinist; Trametinib1件: D10175 2件: MAP2K1,
MAP2K2 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬4件: 2, 34, 279, 280
134 Tranexamic acid 1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬6件: 46, 70, 215, 227, 288, 299
135 Tranilast 1件: Tranilast1件: D02027 --4件: 46, 84, 106, 113
136 Trazodone 1件: Trazodone2件: D00820 ,
D08626 		4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 2
137 Tregalizumab 1件: Tregalizumab---1件: 46
138 Trehalose 2件: Cabaletta; Trehalose---3件: 2, 18, 113
139 Tremelimumab 1件: Ticilimumab1件: D06657 1件: CTLA4 💬4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 96
140 Treosulfan 2件: OVASTAT; Treosulfan1件: D07253 --6件: 13, 19, 62, 65, 283, 286
141 Treprostinil 4件: Remodulin; Treprostinil; Treprostinilo; Tyvaso1件: D06213 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 51, 84, 85, 86, 88, 210
142 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
143 Triacetin 1件: Glyceryl triacetate1件: D00384 --1件: 307
144 Triamcinolone 4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
145 Tricaprylin 2件: Caprylic Triglyceride; Tricaprilin---2件: 13, 145
146 Trichloroethylene 0件: ---1件: 6
147 Tricyclazole 1件: Beam---2件: 6, 51
148 Triethylenetetramine 5件: Cufence; Cuprior; TETA; Trientine; Triethylenetetramine---3件: 50, 58, 171
149 Trifluoperazine 1件: Trifluoperazine3件: D00799 ,
D01448 ,
D08636 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284
150 Triheptanoin 1件: Triheptanoin1件: D11465 --10件: 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
151 Trihexyphenidyl 1件: Trihexyphenidyl2件: D00787 ,
D08638 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
152 Trimebutine 1件: Trimebutine1件: D08639 2件: OPRK1,
OPRM1 💬		3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 51
153 Trimetazidine 1件: Trimetazidine1件: D08642 --3件: 2, 58, 86
154 Trimethaphan 1件: Trimethaphan1件: D00612 1件: CHRNA10 💬1件: Neuroactive ligand-receptor interaction 💬1件: 17
155 Trimethobenzamide 3件: Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride2件: D02733 ,
D08643 		--1件: 6
156 Trimethoprim 2件: Bactrim; Trimethoprim2件: D00145 ,
D06236 		--8件: 36, 44, 49, 60, 61, 85, 298, 299
157 Tripterygium wilfordii whole 2件: Tripterygium; Tripterygium Wilfordii---8件: 46, 66, 67, 96, 162, 222, 224, 271
158 Triptolide 1件: Triptolide---1件: 67
159 Triptorelin 2件: GnRH; Triptorelin1件: D06247 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬2件: 49, 76
160 TRO19622 1件: TRO19622---3件: 2, 3, 13
161 Trofinetide 1件: Trofinetide---1件: 156
162 Tromethamine 4件: Tham; Tris; Trometamol; Tromethamine1件: D00396 --5件: 51, 96, 97, 226, 299
163 Tropicamide 1件: Tropicamide1件: D00397 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 19
164 Tropifexor 1件: Tropifexor1件: D11548 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
165 TRU-015 1件: TRU-015---3件: 46, 49, 222
166 Tryptophan 2件: Propanoic acid; Tryptophan1件: D00020 --2件: 6, 75
167 TU-100 1件: TU-100---1件: 96
168 Tulobuterol 1件: Tulobuterol1件: D02151 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
169 Turmeric 3件: Curcuma Longa; Curcuma Longa Extract; Turmeric---5件: 96, 140, 144, 158, 299
170 Typhoid Vaccine Live 1件: Vivotif---1件: 97
171 Tyramine 1件: Tyramine---1件: 6
172 Tyrosine 4件: Alanine; L-tyrosine; Propanoic acid; Tyrosine1件: D00022 --5件: 6, 75, 86, 111, 298