Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CDK4 2件: Tight junction, Viral carcinogenesis D10688 Abemaciclib 1件: 34
2 CFTR 2件: Tight junction, Vibrio cholerae infection D09916 Ivacaftor 1件: 299
3 CFTR 2件: Tight junction, Vibrio cholerae infection D10134 Lumacaftor 1件: 299
4 CFTR 2件: Tight junction, Vibrio cholerae infection D11041 Tezacaftor 1件: 299
5 CFTR 2件: Tight junction, Vibrio cholerae infection D11423 Deutivacaftor 1件: 299
6 CFTR 2件: Tight junction, Vibrio cholerae infection D11507 Elexacaftor 1件: 299
7 CFTR 2件: Tight junction, Vibrio cholerae infection D11724 Galicaftor 1件: 299
8 ERBB2 1件: Tight junction D04024 Lapatinib 3件: 34, 74, 75
9 ERBB2 1件: Tight junction D08108 Lapatinib 3件: 34, 74, 75
10 ERBB2 1件: Tight junction D11772 Tesevatinib 1件: 67
11 MAP3K5 2件: Tight junction, TNF signaling pathway D10988 Selonsertib 1件: 86
12 PRKAA1 1件: Tight junction D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
13 PRKAA1 1件: Tight junction D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
14 PRKAA2 1件: Tight junction D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
15 PRKAA2 1件: Tight junction D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
16 PRKCE 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D09671 Sotrastaurin 1件: 97
17 ROCK1 3件: Vascular smooth muscle contraction, Tight junction, Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
18 SRC 5件: VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib 2件: 2, 67
19 SRC 5件: VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib 2件: 51, 85
20 SRC 5件: VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib 2件: 51, 85
21 SRC 5件: VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib 3件: 6, 89, 272
22 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00349 Isradipine 1件: 6
23 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00437 Nifedipine 2件: 50, 81
24 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
25 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00615 Amlodipine 4件: 13, 51, 67, 298
26 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00616 Diltiazem 3件: 51, 58, 86
27 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00617 Nicardipine 2件: 70, 86
28 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00619 Verapamil 3件: 96, 140, 167
29 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01173 Cilnidipine 1件: 67
30 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01908 Nilvadipine 1件: 90
31 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D02356 Verapamil 3件: 96, 140, 167
32 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D02914 Amlodipine 4件: 13, 51, 67, 298
33 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D03830 Diltiazem 3件: 51, 58, 86
34 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D05442 Perhexiline 2件: 58, 272
35 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07450 Amlodipine 4件: 13, 51, 67, 298
36 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07845 Diltiazem 3件: 51, 58, 86
37 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08270 Nicardipine 2件: 70, 86
38 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08340 Perhexiline 2件: 58, 272
39 CACNA1D 3件: Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08441 Propiverine 1件: 226
40 ROCK2 4件: Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
41 ROCK2 4件: Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D11815 Belumosudil 1件: 51